Instructions for use of vaginal and rectal suppositories geneferon - composition, side effects and analogues. Genferon candles reviews Properly administer candles Genferon

Tradename

GENFERON® LIGHT

International non-proprietary name

Dosage form

Suppositories 125,000 IU, 250,000 IU for vaginal or rectal administration

Compound

One suppository contains

active substances:

Excipients: dextran 60,000, macrogol 1500, polysorbate 80, T2 emulsifier, sodium hydrocitrate, citric acid, purified water, hard fat.

Description

Suppositories of white or white color with a yellowish tint are cylindrical in shape with a pointed end, uniform on a longitudinal section. An air rod or a funnel-shaped recess is allowed on the cut.

Pharmacotherapeutic group

Immunomodulators. Immunostimulants

ATX code L03A

Pharmacological properties

Pharmacokinetics

With rectal administration of the drug, a high bioavailability (more than 80%) of interferon is noted, and therefore both local and pronounced systemic immunomodulatory effects are achieved. When intra vaginal application due to the high concentration in the focus of infection and fixation on the cells of the mucous membrane, a pronounced local antiviral, antiproliferative and antibacterial effect is achieved, while the systemic effect, due to the low absorption capacity of the vaginal mucosa, is insignificant.

The maximum concentration of interferon in the blood serum is reached 5 hours after rectal or vaginal administration of the drug. The main route of excretion of α-interferon is renal catabolism. The half-life is 12 hours, which necessitates the use of the drug 2 times a day.

Pharmacodynamics

GENFERON® LIGHT - combination drug, the action of which is due to the components that make up its composition. It has a local and systemic effect.

The composition of the drug GENFERON® LIGHT includes a recombinant human interferon alpha-2b, produced by a strain of the bacterium Escherichia coli, into which the human interferon alpha-2b gene has been introduced by genetic engineering.

Activation under the influence of interferon of leukocytes contained in all layers of the mucous membrane ensures their active participation in the elimination of pathological foci; in addition, due to the influence of interferon, the production of secretory immunoglobulin A is restored. The antibacterial effect is mediated by reactions immune system enhanced by interferon.

Taurine contributes to the normalization of metabolic processes and tissue regeneration, has a membrane-stabilizing and immunomodulatory effect. Being a strong antioxidant, taurine directly interacts with reactive oxygen species, the excess accumulation of which contributes to the development of pathological processes. Taurine helps to preserve the biological activity of interferon, enhancing the therapeutic effect of the drug.

Indications for use

as a component complex therapy- for the treatment of acute respiratory viral infections and other infectious diseases of bacterial and viral etiology in children

for the treatment of infectious and inflammatory diseases of the urogenital tract in children and women, including pregnant women, against the background of specific therapy prescribed and controlled by a physician

Dosage and administration

The drug can be used in adults both vaginally and rectally:

in children - only rectally!

The route of administration, dosage and duration of the course depend on the age, specific clinical situation and are determined by the attending physician.

In adults and children over 7 years of age, GENFERON® LIGHT is used at a dosage of 250,000 IU. In children from birth to 7 years of age, it is safe to use the drug at a dosage of 125,000 IU of interferon alfa-2b per suppository. In women who are 13-40 weeks pregnant, the drug is used at a dosage of 250,000 IU of interferon alfa-2b per suppository.

Acute infectious and inflammatory diseases of the urogenital tract in children: 1 suppository rectally 2 times a day with a 12-hour interval for 10 days against the background of specific therapy prescribed and controlled by a doctor.

Infectious and inflammatory diseases of the urogenital tract in pregnant women: 1 suppository (250,000 IU) vaginally 2 times a day with a 12-hour interval for 10 days against the background of specific therapy prescribed and controlled by a doctor.

Infectious and inflammatory diseases of the urogenital tract in women: 1 suppository (250,000 IU) vaginally or rectally (depending on the nature of the disease) 2 times a day with a 12-hour interval for 10 days against the background of specific therapy prescribed and controlled by a doctor. With protracted forms 3 times a week every other day, 1 suppository for 1-3 months.

Acute respiratory viral infections and other acute viral diseases in children: 1 suppository rectally 2 times a day with a 12-hour interval in parallel with the main therapy for 5 days. If, after a 5-day period of treatment, the symptoms of the disease do not decrease or become more pronounced, the patient should consult a doctor. According to clinical indications, it is possible to repeat the course of treatment after a 5-day interval.

Chronic infectious and inflammatory diseases of viral etiology in children: 1 suppository (250,000 IU) rectally 2 times a day with a 12-hour interval in parallel with standard therapy for 10 days. Then within 1-3 months - 1 suppository rectally at night every other day.

Side effects

The drug is well tolerated by patients.

Very rare (less than 1 in 10,000 cases)

- allergic reactions (single reports).

These phenomena are reversible and disappear within 72 hours after cessation of administration. Continuation of treatment is possible after consultation with a doctor.

So far, no severe or life-threatening side effects have been observed.

Contraindications

- individual intolerance to interferon and other substances that make up the drug

Drug Interactions

GENFERON® LIGHT is most effective as a component of complex therapy. When combined with antibacterial, fungicidal and antiviral drugs, mutual potentiation of action is observed, which makes it possible to achieve a high total therapeutic effect.

special instructions

Use with caution in exacerbation of allergic and autoimmune diseases.

Pregnancy and lactation

Clinical studies have proven the efficacy and safety of GENFERON® LIGHT in women at 13-40 weeks of pregnancy. The safety of the drug in the 1st trimester of pregnancy has not been studied.

It has no restrictions for use during lactation.

Features of influence medicinal product on the ability to manage vehicle or potentially dangerous mechanisms

The drug GENFERON® LIGHT does not affect the performance of potentially dangerous species activities requiring special attention and speed of reactions.

Overdose

No cases of overdose with GENFERON® LIGHT have been reported. In case of accidental simultaneous administration of more suppositories than prescribed by the doctor, further administration should be suspended for 24 hours, after which treatment can be resumed according to the prescribed scheme.

Genferon vaginal suppositories exhibit local and systemic immunostimulatory effects, the drug was developed by Russian scientists.

General characteristics of the drug

Genferon is not an antibiotic, but an immunomodulatory drug. Its structure includes three basic ingredients - interferon α-2b, taurine and benzocaine. Influence the specified drug on the body is determined by the properties of its main content - interferon alpha-2b. It is this substance that destroys the structure of viruses and chlamydia.

In the process of using Genferon suppositories, activation of immunocompetent cells is observed. Due to this, the natural protection of the body from the effects of pathogenic agents is provided. Interferon stimulates the formation of class A Ig, which is synthesized in the epithelial cells of the intestinal mucosa.

Taurine is a sulfonic acid formed in the body from the amino acid cysteine. This compound normalizes metabolic processes in the affected organs, enhances the process of tissue regeneration, exhibits hepatoprotective, anti-inflammatory, reparative, antioxidant and membrane-stabilizing effects.

Taurine also prevents the formation and accumulation of products of lipid peroxidation and oxidative modification of proteins in cells. The above compound enhances the biological activity of interferon. Benzocaine has a local anesthetic effect, blocks the appearance of pain.

Candles Genferon improve the general condition of the patient, eliminate such unpleasant symptoms as pain, itching and burning.

Anestezin reduces the permeability of biomembranes for Na + ions, displaces calcium ions from receptors located on the inner surface of the membrane, and blocks the transmission of nerve impulses. In the process of using the drug, the analgesic effect can be traced in just a few minutes. Anesthesia penetrates into lymphatic system, resulting in a systemic effect of the drug.

In addition to the basic elements, Genferon also includes additional substances:

• deionized water;
• dextran 60000;
• sodium citrate;
• twin 80;
• polyethylene glycol 1500;
• citrate acid;
• emulsifier T 2 ;
• animal triglycerides.

Note: Genferon exhibits a pronounced therapeutic effect, which allows to effectively eliminate chronic inflammatory reactions in the organs of the genitourinary apparatus. In addition, according to many scientists, the drug is the safest among analogues.

Indications for use

Many are looking for information on how and in what cases can Genferon be used? The instructions for use state that this remedy can be used as an effective immunostimulant. There are also references to the fact that this medication can be used as an independent antiviral agent.

Genferon is prescribed for both intravaginal and rectal use. The method of administration of the drug and its dosage is determined by gender, age and severity. clinical course illness.

With rectal or vaginal use, the active ingredients of the drug penetrate the blood and lymph very quickly. Some of the drug remains on the mucous membrane and has a local effect. In the presence of extensive inflammatory processes in patients, the vaginal setting of suppositories is combined with rectal.

The highest level of interferon in the blood plasma is observed five hours after the use of the suppository. Since the half-life of the drug is about twelve hours, it is best to use it twice a day.

The course of therapy should be at least ten days. In the presence of chronic pathologies, the drug can be used for up to three months. In this case, it is better to use the medicine every other day.

Genferon is effectively used in the presence of the following pathologies:

• andexite;
• bartholinitis;
• colpitis;
• chlamydia;
• trichomoniasis;
• ureplasmosis;
• mycoplasmosis;
• balanitis;
• bacterial vaginosis;
• anogenital herpesvirus infection;
• vulvovaginitis;
• cystitis;
• urogenital candidiasis;
• prostatitis;
• urethritis;
• gardnerellosis;
• papillomavirus infection;
• erosion and ectropion of the cervix.

The main advantages of the immunomodulator include the following indicators:

• high bioavailability (efficacy) of the drug;
• pronounced antiviral, immunomodulatory, antimicrobial, antiproliferative, antioxidant, reparative action;
• optimal price / quality ratio;
• the possibility of using during menstruation;
• ease of use;
• the possibility of complex use with other medicines.

Despite the excellent characteristics, suppositories in gynecologists cannot be used on their own. It is very important to consult a specialist before using medications. This is especially true for patients who have problems with dysfunction of the cardiovascular and endocrine system(hypertension, diabetes, obesity, Basedow's disease, hypothyroidism, etc.).

Features of use during pregnancy and ureaplasmosis

Many expectant mothers ask: "Is it possible to use Genferon during pregnancy?". As a result of many years of research, researchers have proven the safety of intravaginal use of the drug from 13 to 40 weeks of pregnancy.

Candles are actively used for the treatment of infectious pathologies of the genitourinary apparatus in the second trimester of pregnancy. The bioactive ingredients that make up the drug activate a number of enzymatic reactions in the mother's body, which prevent the virus from spreading. This increases the body's immune resistance.

Genferon is prescribed for the treatment of trichomoniasis, thrush, anogenital herpesvirus infection, relief of pain and itching in the genital area. With ureaplasmosis, immunostimulants are best combined with antimicrobial drugs.

The treatment regimen for ureplasma is chosen by the attending physician. On average, the duration of the course of therapy is from two to three weeks. For effective elimination ailment, the doctor prescribes antibiotics and a suppository Genferon.

Treatment of ureaplasma in women with the help of this medication occurs according to the scheme: a course of taking 10 days, 2 suppositories per day. The chronic form of ureaplasmosis requires longer therapy.

Often, Genferon is prescribed after childbirth. However, breastfeeding is not a contraindication. The suppository has proven itself in the treatment of various anomalies associated with dysfunction of the genitourinary apparatus.

Interaction with other medicines and analogues of the drug

The complex use of Genferon with antibacterial agents enhances the effectiveness of the treatment of infectious pathologies. The following medicines enhance the analgesic effect of benzocaine.

Non-steroidal anti-inflammatory drugs:

Sulfonamides together with Genferon should not be prescribed, as they lose some of their activity against pathogenic bacteria. Not a bad result is obtained when the immunomodulator is used together with fat- and water-soluble vitamins (tocopherol and ascorbic acid).

Genferon does not affect the ability to drive a car at all, does not interfere with the performance of hazardous activities that require heightened attention and concentration. Analogues are represented by such drugs as Giaferon, Kipferon, Vitaferon.

Side effects of the drug and contraindications

In the process of using Genferon, a number of undesirable phenomena may appear:

• allergic skin rashes;
• sleep disturbance;
• hyperthermia;
• chills;
• colic;
• anorexia;
• arthralgia;
• myalgia;
• itching and burning in the perineum;
• migraine;
• dizziness;
• hyperhidrosis;
• increased fatigue;
• loss of appetite;
• thrombocytopenia and leukocytopenia.

If such phenomena are detected, it is necessary to stop taking the medication and seek the advice of a specialist.

The presence of hypersensitivity or allergy to any ingredient of the drug is an absolute contraindication to its use. The medication should also be limited in the following cases:

• the presence of autoimmune pathologies (diffuse toxic goiter, glomerulonephritis, diabetes mellitus, rheumatoid arthritis, Hashimoto's thyroiditis, erythematous chroniosepsis, multiple sclerosis etc.);
• exacerbation of allergic reactions;
• I trimester of pregnancy;
• epilepsy;
• severe diseases of the heart, liver and kidneys;
• children under the age of seven.

A qualified specialist should decide on the appointment of Genferon or its analogues, it is not worth self-medicating.

Reviews

Reviews of doctors and patients indicate that the above medicine is well tolerated and practically does not cause various complications. Practitioners claim that Genferon, unlike its analogues, exhibits a pronounced analgesic and regenerative effect. This is especially true in the treatment of diseases of the cervix. The anesthetic included in the structure of the drug perfectly copes with its function.

Doctors assure that Genferon is absolutely safe, because it is not an antibiotic. That is why it can be prescribed even to patients during the period of bearing a child and breastfeeding him.

This medication almost never shows side effects, but if the dosage is not observed, some discomfort in the anogenital region may be observed. That is why before taking the medication, you should consult a doctor, or at least carefully study the instructions for using the drug. Patient reviews confirm the information that Genferon is a fairly effective antiviral agent, which, with complex treatment, shows an excellent result.

Also, patients note that the drug does not contain oils and paraffin, so it never stains underwear. Due to this, the pharmaceutical agent does not cause any discomfort to women. In most cases, reviews of the above described drug are positive. However, negative reviews can also be found on the Internet, which is obviously related to misuse medication or the presence of an allergy to its components.

Summing up, it should be noted that Genferon suppositories are an effective, safe pharmaceutical substance with antiviral and immunomodulatory effects, used to treat various pathologies of the genitourinary system of men and women.

Genferon candles - instructions for use, dosages, analogues and prices

Latin name: Genferon

Active ingredient: Interferon

alpha 2b + Taurine + Benzocaine

Manufacturer: Biocard, Russia

Pharmacy dispensing condition: By prescription

"Genferon" is an immunomodulator and at the same time an antiviral agent. Its use allows you to effectively deal with various inflammatory processes and a number of pathogens of infectious diseases. First of all, this drug is used for diseases of the genitourinary system in women and men (thrush, genital herpes, papillomas, cystitis, prostatitis and others).

If the drug is administered rectally, the systemic effect of its use is achieved, which makes it possible to treat viral and bacterial diseases with its help. respiratory system, as well as engage in the prevention of diseases, by increasing immunity. For those to whom the doctor prescribed "Genferon", instructions for its use are simply necessary.

Indications for use

Reception of "Genferon" is shown at various infectious diseases, the causative agents of which are viruses, bacteria, protozoa, fungi. It is used to treat:

• Diseases of the male and female genital area caused by the herpes virus, HPV (human papillomavirus), gardnerella, mycoplasma, ureplasma, chlamydia, trichomonas, candida and other microorganisms
• Colds - ARI and ARVI, acute bronchitis etc.
• Diseases of the urinary tract, in particular, bacterial chronic cystitis.

Compound

It includes three active ingredients and, complementing each other in medicinal properties:

• Human interferon alpha-2b, recombinant (rhIFN-α-2b). Obtained by synthesis coli who have received the corresponding gene. Has a pronounced immunomodulatory, antiviral and antibacterial effect
• Taurine. Antioxidant and membrane stabilizer. Raises efficient work interferon, as well as repair of damaged tissues
• Benzocaine (sometimes an anesthetic is used instead). A local anesthetic.

In addition to the main active ingredients, candles include additional substances: solid fat and others (T2 emulsifier, sodium citrate, purified water, and others).

Medicinal properties

"Genferon" candles can be used:

• Rectally. In this case, a complex effect on the body is provided, since the drug is well absorbed into the blood and lymph flow through the mucous membrane of the rectum.
• Vaginally. The permeability of the vaginal epithelium is much lower than that of the intestine. Therefore, in this case, local action"Genferon".

Pharmacological features of the drug are determined by the combined effect of the impact of its constituent parts:

• Interferon alpha-2b has an antiviral effect by suppressing the replication of viruses (HPV, herpes, and others). The immunomodulatory effect is achieved by increasing the concentration of phagocytes, monocytes, macrophages and other cells related to natural killers. This contributes to the immune response to infection, the destruction of its foci and the resumption of the production of antibodies of the Ig A type there. Mediated immunoreactions determine the antimicrobial effect of "Genferon"
• Taurine catalyzes the action of interferon; plays an antioxidant role, removing reactive oxygen species and thereby reducing inflammation; promotes cellular regeneration
• Benzocaine blocks pain impulses in nerve cells which produces a local anesthetic effect. It is not absorbed into the blood, affecting the injection site.

The concentration of the main active substance - interferon - decreases after 12 hours. Therefore, to achieve the maximum therapeutic effect, the drug should be used twice a day. Its components are excreted from the body by the kidneys.

The average price is from 350 to 750 rubles.

Release form

"Genferon" candles are cone-shaped suppositories with a pointed tip. The color is white, there may be a light yellow tint. Due to the excipients, they do not melt in the hands, which is convenient when administered.

There are four types of suppositories that differ in the concentration of interferon: “Genferon” IU, “Genferon” IU, “Genferon” IU and “Genferon light” (which you can read about here).

The carton can contain 5 or 10 suppositories packed in a plastic shell.

Mode of application

Candles are administered vaginally or rectally, depending on the gender of the patient, the nature of the disease and the prescribed therapy.

For the treatment of diseases of the genitourinary system, women are prescribed 2 times in 12 hours, one suppository with a dosage of 500 thousand IU or 1000 thousand IU. As a rule, this is a vaginal administration. The duration of treatment is up to 10 days. During treatment chronic form diseases are used three times a week for 1 candle, with an interval of one day, for 1-3 months.

You can use candles during menstruation.

In acute infectious inflammation of the female genital tract, complex therapy is used:

1. In the morning vaginally Genferon 500 thousand IU
2. In the evening Genferon 1000 thousand IU rectally and additionally vaginal suppositories with an antibacterial effect (for example, Hexicon).

Men, in particular "Genferon" for prostatitis, are shown to use suppositories rectally twice a day, with a dosage of either IU, depending on the severity of the disease. Use the drug for no longer than 10 days.

Under the supervision of a doctor, you can use "Genferon" for children, with different dosages, depending on the age of the patient:

• 1-7 years old - the pediatrician may prescribe "Genferon Light" (IU)
• 7-14 years - the dosage is increased to 250 thousand IU
• Over 14 years old - dosages similar to adults: 250 thousand IU, 500 thousand IU, or same IU, depending on the severity of the disease.

Candles, which are slightly smaller than usual, are injected into the rectum after 12 hours. Duration of admission - 5 days. If the child has a relapse of a chronic disease or the disease has taken a protracted form, the doctor may add another 5-day course of treatment.

It is possible to use the drug for prophylactic purposes: one suppository at night, every other day. Preventive use of the drug is from 1 to 3 months.

During pregnancy and breastfeeding

When deciding whether to use "Genferon" for the treatment of pregnant women, the doctor must balance the benefits for the mother to the harm that can be done to the child. The drug is prescribed no earlier than the 12th week of pregnancy. This drug is used in systemic therapy with identified ureaplasma, thrush, herpes virus, HPV, cystitis and other viral and bacterial diseases.

"Genferon" is not prescribed during lactation.

Contraindications

It is forbidden to use candles under the following conditions: the first trimester of pregnancy and an individual allergic reaction to the substances that make up it.

Precautionary measures

Restriction to the use of the drug are exacerbations of autoimmune diseases and allergies of various etiologies.

"Genferon" and alcohol are combined in very small doses of the latter. It is not recommended to exceed it, since alcohol worsens the effect of interferon, but at the same time increases side effects. Therefore, "Genferon" and alcohol is a completely dubious combination, as in most cases with drugs.

Cross-drug interactions

The use of "Genferon" with vitamins E and C, which accelerate the action of interferon, is shown.

In complex therapy, the drug is prescribed with other antimicrobial drugs or antibiotics. For example, it goes well with Terzhinan vaginal suppositories. They include:

• The antifungal agent nystatin
• Aminoglycoside antibiotic neomycin sulfate
• A substance of the imidazole group ternidazole, which works against anaerobic microorganisms, including Trichomonas and Gardnerella
• The corticosteroid prednisolone sodium metasulfobenzoate is a local anti-inflammatory agent.

"Terzhinan" with "Genferon" effectively interact with cystitis, thrush and other infectious diseases of the genitourinary system.

Another antiseptic that interacts well with Genferon is Hexicon. Its main active ingredient is chlorhexidine. "Hexicon" is produced in the form of vaginal suppositories and a solution. Effective against a number of infectious agents of various etiologies and locations.

Side effects

Basically, there are local symptoms of allergies: itching and burning in the vagina. They go away by themselves a couple of days after the end of the drug. The possibility of its further use should be discussed with your doctor.

When using candles with a total dose of IU per day, reactions are possible that are characteristic of all types of interferon:

• On the part of the hematopoietic system - a decrease in the content of platelets and leukocytes in the blood (thrombocyto- and leukopenia)
• From the side of the central nervous system- headaches, loss of appetite, fatigue
• From the musculoskeletal system - pain in the muscles and joints (myalgia and arthralgia)
• Others - hyperthermia ( fever body), hyperhidrosis (excessive sweating).

When the temperature rises, paracetamol or ibuprofen (Nurofen) can be used.

Overdose

Until this time, cases of excessive use of the drug have not been recorded.

Terms and conditions of storage

The drug can be stored in the refrigerator, at a temperature not lower than +2 and not higher than +8 degrees, away from children, no longer than two years from the date of manufacture.

Analogues

"Panavir"

Green oak forest, Russia

The main active ingredient is an extract from a plant of the nightshade family Solanum tuberosum. "Panavir" promotes the production of immunoglobulin A and leukocytes. It also increases the body's resistance to various pathogens of infectious diseases. The high efficiency of the drug "Panavir" for the fight against HPV is noted. After applying its various dosage forms, papillomas disappear.

• Several dosage forms: solution for injection, gel for local application, rectal suppositories, inlight spray-gel
• Has a bright antipyretic effect - no need to use additional funds
• Favorably affects the retina of the eyes, the regeneration of the gastric mucosa.

• Not to be used by children under 12 years of age
• High price for injections.

"Viferon"

Almost identical to "Genferon", since the main active ingredient is interferon. "Viferon" is available in the form of a gel, ointment and rectal suppositories with a dosage of: ED, ED, ED, and ED. First dosage forms are used in gynecology for the treatment of genital tract infections in women.

• There are auxiliary substances - vitamins C and E, which enhance the effect of interferon
• Can be used from birth

Genferon candles - instructions for use, analogues, price and reviews

Description

Release form

1. Genferon - contains interferon alpha 2b in the amount of IU.

2. Genferon - contains interferon alpha 2b in the amount of IU.

3. Genferon - contains interferon alpha 2b in the amount of IU.

Compound

1. Human interferon alpha 2b at a dosage of IU, IU and IU.

2. Aminosulfonic acid - taurine in the amount of 0.01 g.

3. Local anesthetic - benzocaine or anesthesin in the amount of 0.055 g.

Absorption, distribution and excretion from the body

The introduction of Genferon into the rectum leads to close contact of the drug with the mucosa, rich in blood and lymphatic vessels, due to which the active components are freely absorbed into the blood. When injected into the rectum, approximately 80% of the dose is absorbed into the bloodstream. The maximum concentration of active components in the blood is observed 5 hours after the administration of suppositories. The high degree of absorption of the drug into the blood allows the drug to have not only a local, but also a systemic effect.

With the introduction of Genferon into the vagina, a grown local effect is achieved with the accumulation of a large part of the dose in the pathological focus. The mucous membrane of the vagina does not have a high absorption capacity, so the entry of active components into the bloodstream is minimal. Due to this circumstance, when administered vaginally, the drug has mainly a local effect, and only a slight systemic effect. The maximum concentration in the bloodstream and in the focus of inflammation on the mucous membrane is reached, on average, 5 hours after the administration of suppositories.

Therapeutic effects (principles of treatment)

Effects of interferon

• antiviral action;
• antibacterial action;
• immunomodulatory action;
• antiproliferative action (stopping the reproduction of pathogenic microorganisms).

Genferon has an antiviral effect by acting on specific enzymes that help stop the reproduction of viruses. In addition to the activation of enzymes, Genferon directly suppresses signals for the reproduction of a viral particle.

Effects of taurine

• strengthening of metabolic processes;
• acceleration of tissue repair processes (regeneration);
• normalizes the properties of cell membranes, increasing the stability and viability of cells;
• anti-inflammatory property;
• immunomodulatory effect;
• antioxidant action associated with the neutralization of free radicals and stop chain reactions peroxidation;
• enhances the activity of interferon alpha 2b.

Effects of benzocaine

1. Blocks the conduction of pain through nerve fibers.

2. Block perception pain sensation outgrowths of nerve cells.

Indications

Genferon is indicated for the following diseases:

• genital herpes;
• chlamydia;
• ureaplasmosis;
• mycoplasmosis;
• candidiasis of the vulva and vagina (for example, chronic recurrent vulvovaginal candidiasis);
• gardnerellosis;
• trichomoniasis;
• human papilloma virus (papilloma and condylomas);
• bacterial vaginosis;
• cervical erosion;
• cervicitis (inflammation of the cervical canal);
• vulvovaginitis (inflammation of the vagina and vestibule);
• bartholinitis (inflammation of the Bartholin glands);
• adnexitis (inflammation of the ovaries);
• inflammation of the prostate gland (prostatitis) in men;
• urethritis (inflammation of the urethra);
• balanitis (inflammation of the glans penis);
• balanoposthitis (combined inflammation of the glans penis and foreskin);
• viral hepatitis.

Contraindications

• autoimmune diseases (eg, Hashimoto's thyroiditis, systemic lupus erythematosus, type I diabetes mellitus, glomerulonephritis, etc.);
• exacerbation of allergic conditions;
• pregnancy up to 12 weeks;
• children's age up to 7 years.

Instructions for use

Scheme of application for women

Scheme of application for men

Scheme of application for children

Overdose

Side effects

Rarely, while taking the drug Genferon, the following side effects develop:

The above side effects most often develop with a daily dose of Genferon more than 0 IU.

Interaction with other drugs

1. Non-steroidal anti-inflammatory drugs:

Sulfanilamide preparations, when used in conjunction with Genferon, lose some of their effectiveness against pathogenic microorganisms.

special instructions

Genferon during pregnancy

The use of Genefron in children

Reviews

The use of Genefron in children - reviews

Genferon or Viferon - which is better?

Analogues

• lyophilisate for the preparation of Avonex solution;
• solution for intramuscular injection Avonex;
• solution for injections Altevir;
• Alfaron lyophilisate (for intranasal administration and for injections);
• solution for injection Alfaferon;
• lyophilizate Betaferon (for subcutaneous administration);
• gel for local use Viferon;
• ointment for local use Viferon;
• rectal suppositories Viferon;
• Genfaxon solution (for subcutaneous injection);
• suppositories vaginal and rectal Giaferon;
• ointment for topical application Diaferon;
• lyophilizate Ingaron (for intramuscular, subcutaneous and intranasal use);
• lyophilisate Interal-P (for injections);
• lyophilizate Interferal (for injections);
• interferon recombinant human dry Rekolin (for injections);
• injection solution - human leukocyte interferon;
• solution for topical application - human leukocyte interferon;
• rectal suppositories - human leukocyte interferon;
• recombinant ointment - Interferon alfa-2 (for local and external use);
• Intron A solution (for intravenous and subcutaneous use);
• gel Infagel (for local use);
• lyophilisate Inferon (for intramuscular injections);
• Infibeta lyophilisate (for injection);
• lyophilisate Laifferon (for intramuscular and ocular use);
• Laifferon solution (for intramuscular and ocular use);
• Lyophilizate Leukinferon (for injection);
• lyophilizate Lokferon (for topical application);
• Pegasys solution in vials and syringe tubes (for subcutaneous injection);
• lyophilisate Intron (for subcutaneous administration);
• Realdiron lyophilisate (for intramuscular and subcutaneous use);
• lyophilizate Reaferon (for injections and topical application);
• lyophilisate Reaferon-EC (for injections and topical application);
• Rebif solution (for subcutaneous use);
• Ronbetal solution (for subcutaneous use);
• Roferon-A solution (for subcutaneous use);
• rectal suppositories Sveferon;
• lyophilizate Sinnoveks (for intramuscular injections);
• Eberon Alpha R lyophilisate (for injections);
• Extavia lyophilisate (for subcutaneous injection).

Instructions for use of vaginal and rectal suppositories Genferon - composition, side effects and analogues

The drug belongs to the category of immunomodulators and at the same time has an antibacterial effect. The use of the drug is justified in the presence of various inflammatory pathologies caused by a number of pathogenic bacteria. Often, Genferon suppositories are used to treat the organs of the genitourinary tract (for thrush, cystitis, prostatitis, genital herpes), while not only the symptoms of the disease are eliminated, but also the cause of inflammation.

Genferon candles - instructions for use

The drug is an immunomodulatory complex of substances that has an antimicrobial, anti-inflammatory effect. As a rule, Genferon is used to treat diseases of the genitourinary system in men and women. The antiviral effect of the drug extends to a significant group of pathogenic microorganisms - bacteria, viruses, fungi, etc. The immunomodulatory effect of suppositories is manifested due to the activation of immune defense links that ensure the destruction of long-lived bacteria that provoke chronic inflammation.

The components of the drug provide systemic and local action, activating certain elements of the immune system that act in the blood and on the mucous membranes. With rectal administration, a systemic effect is achieved, due to which it becomes possible to treat bacterial, viral diseases respiratory system or to prevent many other pathologies by activating immune cells and general strengthening of the protective properties of the body.

Compound

The main component of the drug is human interferon alpha 2B, in the preparation it can be in a dosage of 250, 500 thousand or IU. Other active substances in the composition of the drug are:

• aminosulfonic acid (0.01 g);
• benzocaine or anestezin (0.055 g).

Since the active components need a special environment for the fastest penetration into circulatory system and fixation on the mucous membrane of the vagina or rectum, the basis of the drug is solid fat. All active substances and other auxiliary components are evenly distributed in it, which include:

• emulsifier T2;
• dextran 60 thousand;
• sodium hydrocitrate;
• macrogol 1500;
• lemon acid;
• purified water;
• polysorbate 80.

Release form

The medication is presented as suppositories for rectal or vaginal use. The shape of the suppositories resembles a white cylinder with a sharp end. The internal structure of the candles is homogeneous, an air rod or a small depression in the form of a funnel is visible in the section. The drug is available in packs of 10 or 5 suppositories, depending on the dose of interferon, it is divided into 3 types:

Pharmacodynamics and pharmacokinetics

The introduction of suppositories into the rectum ensures close contact of the mucosa with the drug, due to which the active components of rectal suppositories are absorbed into the bloodstream by 80%. The maximum concentration of interferon and other active substances in the blood is observed 5 hours after the use of Genferon. Good absorption of the drug provides both local and systemic therapeutic effects.

With vaginal application of suppositories, the maximum local healing effect, which is due to the accumulation of most of the drug in the foci of infection. The mucous membrane of the vagina cannot provide high absorption, therefore, in this case, the penetration of the active substances of Genferon into the blood is minimal. The drug undergoes breakdown into metabolites, after which it is removed in the urine within 12 hours.

Candles Genferon - indications for use

The systemic immunomodulatory drug has a wide spectrum of action: it has found application in the complex therapy of various infections of the genitourinary system in women and men. In addition, Genferon is used as an independent drug, and as part of complex treatment with other medicines and methods. Candles with interferon are shown HPV treatment and with such diseases:

• vaginal candidiasis;
• herpes viruses;
• chlamydia;
• mycoplasmosis;
• candidiasis of the vulva;
• ureaplasmosis;
• adnexitis;
• viral hepatitis;
• trichomoniasis;
• erosion of the cervix;
• bartholinite;
• vaginosis;
• cervicitis;
• gardnerellosis;
• urethritis;
• inflammation of the prostate gland;
• other sexual infections and urogenital diseases.

Contraindications

It is forbidden to use suppositories in case of an allergic reaction or sensitivity to certain components of the medication. In addition, conditional contraindications to the drug, which you should definitely tell your doctor about, are:

• autoimmune pathologies;
• pregnancy on early dates(first trimester);
• children's age (up to 7 years);
• allergy in the acute stage.

Method of application and dosage

Candles with recombinant interferon are administered vaginally or rectally, depending on the specifics of the disease and the gender of the patient. Genferon completely dissolves, in contact with the mucous membrane of the rectum or vagina, without causing discomfort. With vaginal administration, a more pronounced local effect is achieved, with rectal administration, a systemic effect is provided. The latter type of drug can even be prescribed for the treatment of acute respiratory viral infections or other infectious pathologies of different localization.

Vaginal suppositories Genferon

In gynecology and in inflammatory pathologies, until the age of 7 years, the drug is prescribed in a dosage of IU. For adults and children over the age of seven, vaginal suppositories are prescribed in an individual dosage, depending on the severity of the disease, its clinical manifestations. For bacterial infections in the urogenital tract, doctors recommend suppositories with a dosage of thousands of IU once a day. The duration of therapy, as a rule, does not exceed 10 days.

If Genferon is used as a local anesthetic and anti-inflammatory agent for the treatment of cervical erosion or another disease, then in gynecology it is prescribed in the following scheme: 1 suppository of 500 thousand IU at night vaginally and rectally. At chronic disease a three-month therapy is prescribed, which involves the introduction of suppositories into the vagina 3 times a week.

Rectal administration

Candles with this use case allow the active substance to enter immediately into the intestines, and then into the blood. Genferon is administered rectally for maximum effective treatment inflammations of different localization and for the treatment of male genital infections. In the case of protracted infectious processes in women, the drug is administered rectally, 1 suppository every second day for 1-3 months. For the treatment of men, suppositories are prescribed rectally at a dosage of 500 thousand or 1 million IU, while the use pattern remains the same.

Pediatricians prescribe Genferon Light to children, the instruction of which implies the following treatment regimen:

• with viral infections - 2 suppositories rectally with an interval of 12 hours (therapy lasts 5 days, then a break for 5 days follows and the treatment is repeated);
• with viral chronic infections child Genferon is administered rectally at night every other day (the course is 1-3 months).

Candles Genferon - instructions, application, prices, analogues and reviews

Genferon - candles for the treatment of genital infections. One suppository may contain 125, 250, 500 or 1000 thousand interferons (in the instructions there is information on choosing a dosage). In addition to urogenital diseases, genferon is effective against common infections - viruses, bacteria, fungi. What provides the therapeutic properties of the drug? And how to use it to treat genital infection?

Genferon - composition and action

Genferon is produced in the form of suppositories (suppositories) for insertion into the vagina or anus. Therapeutic effect Genferon provide three active components:

• interferon (its amount can vary - 125, 250, 500 or thousand IU in 1 suppository);
• taurine (0.01 g in 1 suppository);
• benzocaine (0.055 g);

The shape of the suppository and the solid consistency of the preparation are provided by auxiliary components - fat, emulsifier, sodium citrate, citric acid, polyethylene oxide. What action does each component of geneferon provide?

Interferon

Interferon is a substance that is produced by the immune system. In the human body, interferon is formed when foreign cells invade ( predominantly viruses). Human interferons are conditionally divided into three groups (alpha, beta and gamma - α, β and γ). When various viruses invade, they form different types interferons.

Genferon suppositories contain recombined interferon alfa-2b. It is effective against a number of viral infections, many pathogenic bacteria, and some types of cancer. The word recombination means that the medicinal substance is not a blood product. It was obtained without the use of a donor's blood. How is interferon synthesized?

Interferon recombination is produced by Escherichia coli bacteria. The human interferon gene is inserted into their DNA. As a result, bacteria begin to produce (synthesize) human interferon, which fights infection (suppresses the synthesis of new viruses, stops their reproduction and further distribution). It also stimulates the formation of other cells of the immune system ( macrophages).

Thus, the drugs have a double effect. Firstly, they introduce additional interferons into the blood (the help of someone else's immunity to fight infection). Secondly, they stimulate the formation of their own immune cells.

Taurine

Taurine - has a versatile effect on the human body ( prevents convulsions, improves heart function and breakdown of fats, restores the retina). It also protects cells, is responsible for their tone, restores the structure. In the human body, taurine is found in many vital organs.

Note: Pharmaceutical industry uses this substance extensively. It is part of different drugs- for the treatment of liver, heart, diabetes, various infections.

As part of suppositories, taurine is a wound healing and anti-inflammatory component. It promotes tissue epithelialization, accelerates the healing of wounds and skin rashes. Reduces the area of ​​inflammation.

In addition, taurine retains the biological activity of interferon, and thus enhances the therapeutic effect.

Benzocaine

Benzocaine is an anesthetic component of Genferon suppositories (anesthetic). It blocks the passage of the nerve impulse and prevents the appearance of pain. An anesthetic is especially needed for painful infections and their relapses (for example, with herpes zoster, when the blistering rash not only itches, but also causes severe pain).

Genferon - stimulates own immunity. It strengthens the weak immune response, help to cope with the disease or infection at the moment, but do not always prevent infection and disease in the future. Therefore, the use of geneferon should not be uncontrolled, it is impossible to turn to treatment with immunostimulants for any reason. The drug is used for complex protracted infections or a low level of immunity.

Genferon: side effects and contraindications

For the drug geneferon, the instruction does not regulate any contraindications. However, for interferon (the main active ingredient in suppositories), the list of contraindications is quite wide. It is not recommended to be treated with drugs with interferon for the following diseases:

• Disorders of the heart, liver, kidneys.
• Disturbances in the central nervous system (namely, epilepsy).
• Diseases of the thyroid gland (with a patient thyroid gland interferon can cause hyperthyroidism).

What are the side effects of interferon treatment?

• s Cardiac arrhythmias. With great care, drugs are used in the treatment if there was a heart attack before.
• Drowsiness, headache. The drugs should not be combined with sedatives or sleeping pills.
• Loss of appetite, nausea and diarrhea - usually in those who have liver or biliary tract disease.
• s Allergic rashes.

More often than others side effects appear together with large doses of the drug (500 itys. IU).

In addition, the drug is stranger» immunity. The recombinant component is safe in that it is not produced from blood and cannot become a source of infection. Its danger lies elsewhere - uncontrolled treatment with geneferon reduces one's own immunity, makes a person dependent on interferon intake from outside.

Candles genferon for children

Is Genferon used for children? Despite the novelty of the drug and medical disputes, geneferon is used to treat children from the first days of life. But only when necessary. For example, a child is not able to recover, their own immunity is greatly reduced, the body cannot cope with an infection, or complex surgical treatment is necessary.

Do not use Genferon suppositories for treatment common cold, cough or cold. Even for the treatment of influenza in children, genferon suppositories are used only when protracted course diseases when the immune system is severely weakened and the body is unable to cope with the virus.

Advice: in the treatment of children, the smallest concentration of the active substance is used - Genferon Light 125. Due to the minimum amount of interferon, the likelihood of an allergic reaction from the use of these suppositories is the least.

Release form

The mass of one candle is 1.65g. One package may contain 5 or 10 pieces. The amount of active substance (interferon) is measured in international units - IU.

Genferon contains ME. This minimum dosage is used to treat children infancy and preschoolers up to 7 years old. Candles 125 are called Genferon Light. The use of Genferon Light is recommended not only for the treatment of children, but also for pregnant women (if there is a need to treat a sexual infection).

Genferon contains IU(in each suppository). This dosage is used to treat female genital infections in the initial and middle stages of development.

Genferon contains IU. This dosage is used to treat genital infections in men. It is also used to treat advanced genitourinary diseases in women.

Genferon - contains the maximum dose - IU. Used to treat complex infections, extensive inflammation, mainly in men.

The price of candles depends on the concentration of the active substance. The most expensive - candles IU.

What is treated with geneferon

Instructions for Genferon suppositories provide a list of infections in which the drug has a therapeutic effect:

• Herpes virus - more often used to treat the genital virus, but can also be used for oral and herpes zoster.
• HPV or human papillomavirus.

Bacterial infections:

• Chlamydia.
• Ureplasma.
• Mycoplasma.
• Gardnerellosis.
• Trichomoniasis.

As well as fungi (candidiasis). And yet - vulvovaginitis and cervicitis in women, prostatitis and urethritis in men.

Candles genferon - vaginal and rectal

Preparations with interferon have a form that ensures that the active substance enters the mucous membranes of the external organs. Interferon is destroyed in the stomach. Therefore, Genferon is produced in the form of candles or spray.

Rectal suppositories allow the active ingredient to enter immediately into the intestines, from where it is quickly absorbed into the blood. That's why rectal application is most effective for the treatment of general inflammation, as well as for the treatment of genital infections in men.

Sexual infections of women are treated with vaginal administration of the drug. In this case, geneferon has a local effect - it is almost not absorbed into the blood and is concentrated inside the vaginal cavity (the walls of the genital organs have a low absorption capacity). Almost the entire drug remains inside and has a powerful therapeutic effect - it treats inflammation and destroys the pathogen.

Due to the weak absorption of the drug through the vagina into the blood, only genital infections in women are treated with vaginal administration of suppositories. All other cases of infection are subject to treatment by rectal administration of geneferon.

Often, for the treatment of complex protracted or extensive inflammation in women, vaginal suppositories are combined with rectal.

The use of candles for the treatment of women, men, children

• For the treatment of acute genital infections in women, they put 1 suppository (250 or 500 thousand IU) vaginally, morning and evening. The choice of dosage depends on the extent of inflammation and the causative agent of infection. Course of treatment - 10 days.
• For the treatment of chronic protracted infectious processes in women, 1 suppository is administered every other day within 1, 2 or 3 months.
• For the treatment of men, a dosage of 500 itys is chosen. ME. The treatment plan is the same 2 suppositories per day, 10 days or 1 suppository every other day for a month).

Genferon light is used to treat children. The instruction recommends the following scheme:

• For viral infections - 2 suppositories to the child rectally, with an interval of 12 hours. The course of treatment in children is less than in adults - 5 days. If necessary, extend the course, take a break for 5 days and repeat the treatment.

• In chronic viral infections in children, suppositories are administered rectally at night (every other day). A course of treatment - 1 to 3 months.

Genferon: analogues

The pharmacy industry offers many drugs in which interferon is the main active ingredient. They differ in name, additional components and the form of the drug (drops, spray, suppositories).

Viferon

These are rectal suppositories with interferon without additional substances. Each candle contains from ME. It is used to treat acute respiratory viral infections and pneumonia, intrauterine infection of newborns, hepatitis, genital infections, herpes. Viferon is administered only rectally. The drug is most effective against viruses respiratory tract.

Kipferon

These are suppositories for rectal and vaginal administration. They contain interferon alpha 2 (in the amount of IU) from donor blood, as well as plasma proteins (to stabilize interferon) and immunoglobulins M, A, G. The presence of immunoglobulins, on the one hand, enhances the stimulating effect, increases the effectiveness of the drug in the fight against viruses. On the other hand, it often causes allergic reactions.

Differences between geneferon, kipferon and interferon

These drugs are derivatives of interferon. They have a similar effect on the human body and are used to treat various infectious diseases (urogenital inflammation, common viral or bacterial infections).

Genferon is the most effective immunostimulating drug against genital viruses (herpes, HPV). In the treatment of herpes, it has the advantages of pain relief and speeding up the healing of the rash. Kipferon - more effective for the treatment of intestinal viruses. Viferon - for the treatment of respiratory tract infections. In addition to the listed immunostimulants, there are many other drugs: Laferobion drops, Egiferon solution in ampoules, Lokfiron in the form of an injection solution, Diaferon ointment, Sveferon suppositories and a dozen more trade names and forms with the main active ingredient - interferon.

Having learned after going to the pharmacy the cost of some prescribed drugs, sometimes it’s time to turn to a specialist again - a cardiologist or a psychologist - it all depends on the health and the amount. However, there are drugs that allow you to save money, as they contain several active ingredients at once, for example, Genferon candles. What can they save us from?

Suppositories Genferon are prescribed for the treatment of urogenital diseases caused by viruses, fungi and bacteria. This medicine is prescribed for:

• toxoplasmosis;
• chlamydia;
• mycoplasma;
• any type of herpes;
• vaginal candidiasis;
• trichomoniasis;
• erosion of the cervix;
• cervicitis;
• adnexitis;
• weakened body defenses.

The drug is often prescribed precisely as an immunostimulant, especially for children.

Candles are inserted into the anus or into the vagina 1-2 times, depending on the nature of the disease and the age of the patient. But before dwelling on the nuances of taking, let's figure out what the effect of the drug is based on. Genferon is a combination of three components:

• interferon (helps the blood to develop its own immunity, and also provides additional interferons - substances formed in the blood during the reaction to viruses entering the body);
• taurine (increases interferon, and also accelerates the regeneration of tissue cells, reducing the area of ​​the inflammatory process);
• benzocaine (has an analgesic property).

Such a wide range of effects allows you to effectively stimulate the activity of your own immunity.

Nuances of application

Each suppository contains a different amount of interferons - from 125 to 1000. Depending on the severity of the disease, a weaker or stronger medicine is prescribed. The dosage is determined solely by the doctor on the basis of diagnostic procedures and general condition patient.

Treatment of women

If a woman has an acute genital infection, then, as a rule, it is prescribed 1 suppository vaginally with a dosage of 250-500. You need to use suppositories 2 times a day. The course of treatment is not recommended to delay more than 10 days. Otherwise, irreversible processes may begin in the body associated with the “relaxation” of the immune system, which gets used to the fact that it is backed up by interferon.

If the lady is being treated for a protracted infection, then the regimen is somewhat different: 1 suppository at bedtime, but for 1-3 months.

Treatment for men

Representatives of the strong half of humanity are prescribed Genferon 500 to increase immunity, as well as in the complex therapy of both sexual partners. Suppositories are applied 2 times a day, after waking up and before going to bed. The course of treatment in this case is about 10 days.

Help for children

Doctors prescribe Genferon from the first days after birth. However, this is possible and advisable only if the baby’s immunity is really weakened, which does not allow him to overcome the infection on his own. Also, the drug is used in cases of preparation for surgery.

For children, Genferon light suppositories are usually prescribed with a dosage of 125 to minimize a possible allergic reaction.

The intensity of treatment depends on the nature of the disease:

Candles Genferon during pregnancy and lactation

Women in the position of suppositories are prescribed only from the 2nd trimester. This is due to the fact that, by activating the protective properties of the immune system, it is possible to provoke the rejection of the fetus being born as a foreign organism. The dosage is calculated individually, depending on the severity of the infection. When lactation, the drug is not prescribed.

Feedback

The instructions for candles "Genferon Light" 125 for children say that this drug stimulates the body's immune abilities after 1-2 doses. This is confirmed by the reviews of mothers, who in this way helped their babies recover more quickly after viral or infectious diseases. The leitmotif of reviews about taking Genferon suppositories for children can be considered the fact that young patients did not experience allergic reactions, and a noticeable therapeutic effect occurred already on the 2nd day.

But women who use Genferon vaginally often complain of a burning sensation in the perineum, violations monthly cycle and heartburn. The last "side effect" is also noted by men. In general, the high efficiency of the drug allows you to "forgive" him for some minor flaws.

Having found out what Genferon candles are and what they are from, you should not immediately rush to buy far from cheap drug. Still, it is better to contact a doctor who can draw a conclusion about how useful suppositories will be for a particular patient. And you should be especially careful when treating children and pregnant women, although in their case this drug is also used and gives a good effect.

Genferon suppositories are a fairly well-known drug that is often prescribed to patients suffering from infectious and inflammatory diseases of the genital tract. It has local anesthetic, restorative and antimicrobial effects, which are provided due to the content of several active ingredients.

Composition and action

There are three active ingredients in Genferon candles.

Alpha-2 interferon plays a key role in influencing the immune system. It increases the activity of cells of the immune system, including leukocytes, which leads to an increase in the secretion of its own protective immunoglobulin. In addition, having a specific effect on pathogens, this substance disrupts the reproduction of viral particles (herpes, human papillomavirus), fungi and bacteria, both resulting from a violation of the microflora (gardnerella) and being independent pathogens (trichomonas, mycoplasma, chlamydia) . As a result of this exposure, a noticeable anti-inflammatory effect of the drug is noted.

The next ingredient is taurine- is an antioxidant and stimulates tissue repair processes, and the last substance (anesthesia) suppresses sensitive receptors, thereby reducing pain, itching and other unpleasant symptoms caused by the disease.

Indications for use and method of application

The list of indications that are described in the instructions does not cover all areas of application of geneferon, but at least describes most of the reasons why this remedy is prescribed. So, suppositories are recommended for use in the treatment of chlamydia, genital herpes, ureaplasmosis, gardnerellosis, trichomoniasis and other similar diseases. In addition, women are recommended to use the drug for symptoms of erosion, colpitis, vulvovaginitis and inflammation of the appendages, and for men it is recommended for urethritis and prostatitis.

The listed indications, which you will see in the annotation, can be supplemented with a couple more important points. So, in practice, gynecologists prescribe geneferon as prophylactic women who have had a miscarriage or a complicated abortion. The action of its components does not allow the activation of a possible latent infection and helps damaged tissues to recover faster and more fully, without the formation of such complications as constrictions in the uterus, fusion of the cervical canal, and so on. In men, the drug is sometimes used in the complex treatment of complex infertility. For example, domestic urologists recommend using geneferon together with antibiotics at the first stage of infertility treatment, to eliminate prostatitis caused by chlamydia and ureaplasmas.

In women, Genferon is used 2 times a day vaginally., course of treatment acute illness is 10-14 days. If the disease is chronic, suppositories are placed every other day, one at a time, for up to 3 months. In male patients, the drug is also used twice a day., and the treatment lasts up to 2 weeks, but suppositories are used rectally.

Side effects and contraindications

From a drug that helps well and has a wide range of indications, you involuntarily expect some kind of catch, for example, unexpectedly strong and frequent side effects. However, as far as geneferon is concerned, this should not be expected. Of the side effects, there are (not often) allergic reactions, as well as a passing burning sensation after the introduction of a candle, which worries for 2-4 days, and then disappears. Any other reactions are extremely rare. The only absolute contraindication to the use of the drug is intolerance to its components.

Questions

• Can Genferon suppositories be used during pregnancy?

Officially, they are allowed starting from the second trimester, but in some cases, with exceptional need and on the recommendation of a doctor, they are also used in the first weeks of pregnancy.

Due to joint disease, I often take anti-inflammatory drugs (sometimes nimesulide). Recently, the gynecologist also prescribed geneferon. Are these medicines compatible?

The combination of non-steroidal anti-inflammatory drugs with geneferon causes an increase in the effect of the latter. A similar effect is observed with the parallel use of M-anticholinergics and some vitamins, and the combination of geneferon and antiviral agents mutually enhances the effects of these drugs.

• During treatment with Genferon, muscle pains and headaches began to appear, chills periodically bother me, the temperature rises slightly - like with a cold. Could this be due to the use of candles? I have been treated with this drug for 2 weeks, I put 3 suppositories a day for a greater effect (the dosage of the drug is 1 million IU). I don't take any other medications, I haven't been to the doctor.

Similar phenomena can be caused by geneferon. In the event that it is used in high doses (the maximum daily dosage is 1 million IU, and not 3 million, as in this case), a rare side effect may occur, which is manifested by the listed symptoms. In order for this not to happen, it is necessary to strictly observe the doses and duration of the course.

• Is it true that geneferon - hormonal drug which can be dangerous?

No, it's not true, and it's not clear where such rumors come from. Genferon is a complex of immunomodulator, antioxidant and anesthetic, which together give a noticeable and lasting effect. The remedy is safe, and its additional advantages are that it is allowed during pregnancy and has a minimum number of side effects and contraindications. All this makes geneferon, if not indispensable, but at least very valuable in the practice of a gynecologist or urologist.

Genferon is a combined immunomodulatory drug with antimicrobial and antiviral effects. It is used in the treatment of respiratory and urogenital infections in adults and children, has a local and systemic therapeutic effect.

Genferon is a unique drug developed by Russian scientists, its effectiveness and safety are confirmed by relevant certificates and clinical research. Genferon has gained popularity in the Russian market and is successfully used in the treatment of many diseases. Let's take a closer look at this drug, talk about it pharmacological action and how to properly apply Genferon for various pathologies.

The action of the drug

Genferon is an antiviral, antimicrobial, anti-inflammatory and immunomodulatory drug. The therapeutic effect of the drug is provided by the active components that make up its composition. The main component is the human protein interferon alpha-2, which is produced by the cells of the body to destroy microbes and viruses. In addition to it, the drug contains anestezin, taurine and a number of auxiliary components.

The antiviral effect of interferon alpha-2 is manifested due to the effect on specific enzymes that signal the cessation of the reproduction of viral particles. The antibacterial effect is achieved as a result of the activation of the cells of the immune system, which allows you to fight pathogenic bacteria.

The immunomodulatory properties of the drug are to increase the activity of killer cells (macrophages, T-lymphocytes), which are able to quickly recognize and destroy pathogenic viruses and bacteria. Genferon promotes the production of antibodies and activates all types of leukocytes, which accelerates the immune response and allows you to effectively eliminate the focus of inflammation.

1. Taurine as part of the drug, it normalizes metabolic processes, accelerates regenerative and membrane-stabilizing processes. This component has a powerful antioxidant effect and prevents the formation of active forms oxygen, thereby reducing the development of the inflammatory process. Taurine supports the biological activity of interferon and enhances the therapeutic effect of the drug.
2. Anestezin ( benzocaine) acts as a local antiseptic and has an analgesic effect, preventing the conduction of a pain impulse along the nerve fibers. This substance is not absorbed into the systemic circulation and has an exclusively local effect.

With rectal or vaginal application of Genferon, the active substances are absorbed through the mucous membranes and quickly enter the tissues and lymph, providing a pronounced systemic effect. Part of the drug remains on the mucosa and has a local effect. A decrease in interferon activity is observed after 12 hours, so the medication should be used twice a day.

Genferon is prescribed for an extensive list of infectious and inflammatory lesions of the genitourinary system in women, children and men. In addition, the drug is used as part of the complex treatment of acute respiratory viral infections and infectious lesions of the upper respiratory tract. Genferon is used for the following pathologies of the urogenital tract:

A lighter form of the drug Genferon Light is used as part of complex treatment viral diseases and urogenital infections. In pediatrics, this drug is prescribed for the treatment of acute respiratory viral infections, bronchitis, tonsillitis, rhinitis, etc.

Forms of release, composition

Genferon is produced in the form of rectal or vaginal suppositories (candles), as well as in the form of a nasal spray.

Instructions for use, dosage

Schemes for the use of Genferon are different, they depend on the age and gender of the patient.

According to the instructions for the use of Genferon, women can use suppositories at a dosage of 250 or 500 thousand IU, depending on the severity of the symptoms of the disease and the severity of the condition. The standard treatment regimen prescribes for 10 days to inject 1 suppository intravaginally twice a day. At chronic course disease, a longer course of treatment is recommended. For 1-3 months, one suppository should be administered every other day.

Pregnant women with a period of 13 weeks or more can use the drug according to the standard scheme for sanitation of the vagina, treatment of inflammatory processes and genital infections. The dosage of the drug should be determined by the doctor.

For men with infections of the urogenital tract, the drug is prescribed at a dosage of 500 thousand or 1 million. ME. Genferon is used rectally, administering one suppository twice a day for 10 days.

For the treatment of children, a lightweight form of the drug is produced - Genferon Light. For the smallest patients under the age of 7 years, Genferon 125 suppositories are prescribed, in children from 7 to 14 years old, the drug can be used at a dosage of 250 thousand IU.

Children are recommended to inject 1 suppository into the rectum twice a day. The procedures are repeated for 5 days. In chronic and protracted diseases, you can extend the course of therapy up to 10 days. In babies, suppositories should be used rectally. It is especially unacceptable to administer suppositories intravaginally to girls under 7 years of age, since at this age the vaginal microflora is not completely formed and is not ready for exposure to aggressive chemicals.

Spray Genferon Light is used for acute respiratory diseases or the flu, and are used for injections into the nose. In this case, one injection is equivalent to one dose of the drug. Instructions for use Genferon Light says that the spray should be used at the first signs of respiratory viral infections in children and adults.

1. Before using the drug, the protective cap must be removed from the vial.
2. Before the first procedure, press the dispenser until a spray cloud appears.
3. The bottle must be kept upright.
4. Injection into each nasal passage is carried out by pressing the dispenser once.
5. After use, the bottle with the drug is closed with a protective cap.
6. To avoid infection, you should use an individual vial with the drug.

The spray can be used up to three times during the day, each time injecting 1 dose of the drug. Treatment is continued for 5 days. The permissible maximum amount of medication that can be used during the day is 10 doses. As a preventive measure in case of hypothermia or contact with a patient with influenza or SARS, you can inject 1 dose of the drug twice a day for a week.

The use of Genferon in both adults and children should be combined with therapy antibacterial drugs and other drugs and include in the treatment regimen the intake of vitamin complexes.

Is it possible to be treated with Genferon during pregnancy? This question interests many patients. Experts warn that it is impossible to use the drug in the form of suppositories in the first trimester of pregnancy. Further, for a period of 13 to 40 weeks, the medication is prescribed by a doctor and used under his supervision, taking into account all possible risks.

In the first trimester of pregnancy, when the organs and systems of the unborn child are laid, the drug can cause unwanted pathologies and increase the risk of abortion. Therefore, its use should be abandoned. Starting from the 13th week, Genferon can be used after consultation with a specialist. Similar restrictions apply to the drug in the form of suppositories, Genferon Light nasal spray is approved for use in pregnant women without restrictions.

During the period breastfeeding the use of suppositories Genferon should be treated with caution. The active components of the drug are not excreted with mother's milk, but they activate aggressive antibodies and cells of the immune system, which penetrate milk without restrictions and, together with suppressed pathogenic microorganisms, can be transmitted to the child. Therefore, at the time of treatment, it is better to stop breastfeeding the baby and temporarily transfer the baby to artificial mixtures.

An absolute contraindication to prescribing the drug is individual intolerance or the presence of allergic manifestations on any of the components that make up the medicinal product. In addition, experts highlight conditions in which the prescription of the drug should be taken with the utmost care, and treatment should be carried out under the supervision of medical personnel. These states include:

• The presence or exacerbation of autoimmune diseases (systemic lupus erythematosus, glomerulonephritis), diabetes 1 type.
• Early pregnancy (before 12 weeks)
• Children's age (up to 7 years)
• Exacerbation of allergies

Particular care should be taken when hypersensitivity or the presence in the patient's history of allergic reactions, since the use of the drug in such cases can lead to undesirable complications.