Tantum® verde lozenges, spray, topical solution. Tantum verde: instructions for use Tantum verde spray indications for use

Tantum Verde: instructions for use and reviews

Spray Tantum Verde is a drug for topical use. He is appointed to complex therapy at inflammatory diseases oral cavity, which are caused by microorganisms sensitive to the drug. The analgesic effect of the drug is observed from the first minute of use.

Dosage form

Dosed spray for topical use. The volume of 1 bottle is 30 ml, it contains 176 doses.

Description and composition

The spray is a colorless transparent liquid that smells like mint.

As active substance the drug contains benzydamine hydrochloride, which in 1 dosage contains 0.255 mg.

As auxiliary components, the drug contains:

• 96% ethyl alcohol;
• glycerol;
• preservative E 218;
• menthol flavor;
• ortho-sulfobenzimide;
• bicarbonate of soda;
• twin 20;
• purified water.

Pharmacological group

The active substance belongs to the group of indazoles, which is a non-steroidal anti-inflammatory agent for topical use. It stops inflammation and pain, has an antiseptic effect.

The active substance stabilizes the cell membrane and blocks the production of prostaglandins, which are responsible for the development of inflammation and pain.

Benzydamine penetrates into the bacterial cell, disrupts metabolic processes and causes the death of the microorganism.

The drug has an antimycotic effect against fungi of the genus. The active substance causes changes in their cell wall and as a result, microorganisms cannot multiply.

When used locally, the active substance is well absorbed through the mucous membranes, and migrates to the focus of inflammation. It is detected in the bloodstream in an amount that is not enough for the development of systemic effects. The drug is excreted mainly in the urine.

Indications for use

for adults

Spray Tantum Verde is prescribed for the relief of pain in inflammatory diseases of the oral cavity:

• inflammation of the gums and tongue, larynx;
• , including those developed against the background of chemotherapy and radiotherapy;
• oral cavity (as part of complex therapy);
• after treatment and resection of the tooth;
• after surgical treatment and injuries (removal of tonsils, fracture of the jaw);
• periodontal disease;
• calculous sialadenitis;
• , tonsillitis.

For inflammatory and infectious diseases the drug is prescribed as part of complex therapy.

for kids

Spray Tantum Verde can be prescribed to children over 3 years old, as it does not contain antibiotics and toxic substances.

The drug should not be used during childbearing and breastfeeding.

Contraindications

Spray Tantum Verde can not be used:

• in children under 3 years of age;
• with individual intolerance to the composition of the drug.

With caution, the medication should be prescribed for intolerance to other non-steroidal anti-inflammatory drugs, patients suffering from bronchial asthma.

Applications and doses

for adults

The spray should be sprayed after meals, 4-8 injections from 2 to 6 times a day. Do not exceed the recommended dosage, the course of therapy is a maximum of 1 week. If after 7 days of treatment there is no improvement, it should be interrupted and consult a doctor to adjust the treatment regimen. While injecting the medication, you need to hold your breath.

Spray as follows:

1. The vial must be held vertically, the cannula (white tube) should be raised so that it is at right angles to the vial.
2. Insert the cannula into the oral cavity and press the sprayer (it is marked with an arrow) as many times as necessary.
3. Return the cannula to its place.

When using the drug for the first time, you need to press the nebulizer, directing the cannula into the air.

for kids

Spray for children 3-6 years old, the drug is prescribed 1 injection for every 4 kg of weight, but the maximum single dosage should not exceed 4 injections. You can spray the spray 2 to 6 times a day.

For children 6-12 years old, the drug is prescribed 4 injections 2-6 times a day.

For adolescents over 12 years of age, the spray is prescribed from 4 to 8 injections at a time, 2-6 times a day.

for pregnant women and during lactation

Tantum Verde spray is not prescribed for pregnant and lactating patients.

Side effects

During use medicinal product The following undesirable effects may occur:

• dryness, burning, numbness in the mouth;
• allergy, which can be manifested by photosensitivity, rashes, itching, Quincke's edema, laryngospasm, anaphylaxis.

In the event of an increase in the listed adverse reactions, as well as the appearance of new ones that are not in the annotation, it is necessary to interrupt therapy and seek medical advice. medical care to adjust the treatment regimen.

Interaction with other drugs

It is not known how the drug interacts with other medicines, since studies in this area have not been conducted.

special instructions

Against the background of the use of the drug, an allergic reaction may develop, in which case it is necessary to interrupt therapy and consult a doctor to prescribe antihistamine and adjusted further treatment regimen.

Sometimes sores in the throat and mouth can be a symptom of a more serious condition. If after 3 days of therapy the patient's well-being does not improve, then it is worth consulting with the doctor.

In patients with bronchial asthma, bronchospasm may begin during the use of the spray.

The drug does not affect the ability to drive a car.

After the drug has been sprayed into the oral cavity, it is not recommended to bathe, drink water or other liquids, or gargle for at least 1.5 hours so as not to wash off the active substance.

Athletes and drivers should be aware that Tantum Verde spray contains ethyl alcohol.

Children under 3 years of age are not recommended to use medicines in the form of a spray, as they can cause laryngospasm, which is manifested by respiratory distress and can provoke the death of a child from asphyxia. That is why children are advised to spray the spray not on the tonsils, but on the inner surface of the cheek.

In addition to the Tantum Verde spray, you can also find the Tantum Verde forte spray on sale, which contains 2 times more active substance. It is produced in a volume of 15 ml and contains 88 doses. In addition, Tantum Verde forte should not be administered to children under 18 years of age. For adults, it is prescribed 2-4 injections from 2 to 6 times a day, for a week. Otherwise, both of these drugs do not have differences.

Overdose

To date, not a single case of overdose with Tantum Verde spray has been registered. If you use it in accordance with the instructions, then an overdose is unlikely.

If the drug is swallowed, the following symptoms of intoxication may occur:

• lack of coordination;
• increased heart rate;
• stop breathing;
• cramps in the abdomen;
• temperature rise;
• fear;
• excitement;
• hallucinations;
• convulsions.

These symptoms can be observed when the drug is swallowed at a dosage several times higher than the therapeutic dose. As a rule, they are observed in children.

There is no specific antidote. Treatment is aimed at eliminating signs of intoxication. The victim is prescribed gastric lavage, induction. Medicines are prescribed to help support the functioning of vital organs.

Storage conditions

Store Tantum Verde spray in a dark place where children cannot get it, at a maximum temperature of 25 degrees. The shelf life of the drug is 4 years.

Name:

Tantum Verde

Pharmachologic effect:

Tantum Verde is a non-steroidal anti-inflammatory agent for topical use. Active substance- benzydamine hydrochloride, a derivative of indazoles. When used locally, it has anti-inflammatory and analgesic properties due to the suppression of prostaglandin synthesis and stabilization of cell membranes. Absorbed through mucous membranes well, accumulates in inflamed tissues. Eliminated by the digestive system (feces) and kidneys (urine).

Indications for use:

It is intended for the treatment of infectious and inflammatory diseases of the oral cavity and pharynx:

Glossitis, gingivitis, stomatitis (including disorders after chemotherapy and radiation therapy),

Pharyngitis, laryngitis, tonsillitis, tonsillitis,

Calculous inflammation of the salivary glands,

periodontal disease,

Candidiasis (as part of complex therapy),

After treatment or extraction of teeth,

After injuries or surgical interventions (including jaw fractures, tonsillectomy, etc.).

Application method:

Tantum-Verde tablets for resorption in the oral cavity are prescribed 1 tablet 3-4 r / day.

Tantum-Verde for topical application (solution) is prescribed 15 ml (1 tablespoon) for rinsing the throat or mouth every 1.5-3 hours for pain relief. The solution is not intended to be swallowed!

Tantum-Verde Spray is used in 4-8 doses (4-8 presses on the sprayer) every 1.5-3 hours. In pediatrics: children from 6 to 12 years old - 4 doses. Children under 6 years old - the dosage is calculated at the rate of 1 dose for every 4 kg of weight, but not more than 4 doses.

Undesirable phenomena:

Feeling of numbness, burning or dryness in the mouth. Allergic reactions (skin rash) and sleep disturbances (insomnia) are possible.

Contraindications:

Tantum Verde solution for topical use is contraindicated in children under 12 years of age,

Tantum Verde tablets should not be administered to patients with phenylketonuria,

Allergic reactions to the components of the product.

During pregnancy:

Tantum Verde is not contraindicated during pregnancy and breastfeeding. Appoint according to indications!

Interaction with other drugs:

No interactions have been reported at this time.

Overdose:

Cases of exceeding the dose are not known.

Release form of the drug:

Tantum Verde - tablets for resorption in the oral cavity - 10 tablets in an aluminum blister, 2 blisters in a cardboard box.

Tantum Verde - solution for topical application (rinsing) - green, transparent, with a characteristic smell of mint, 120 ml in a glass bottle, graduated cap.

Tantum Verde spray - in polyethylene bottles of 30 ml (176 doses) with a dispenser and a pump, a green solution, transparent, with a characteristic mint smell.

Storage conditions:

Tantum Verde is stored at room temperature, in a place that is dark and accessible to children. Shelf life - no more than 4 years. Released without a prescription.

Compound:

Tantum Verde tablets

Active substance (in 1 tablet): benzydamine hydrochloride 3 mg.

Inactive substances: racementol, isomaltose, aspartame, mint flavor, citric acid, lemon flavor, indigo carmine (E132), quinoline yellow (E104).

Tantum Verde solution

Active substance (in 1 ml): benzydamine hydrochloride 1.5 mg (0.15%).

Inactive substances: methyl parahydroxybenzoate, glycerol, menthol flavor, ethanol, saccharin, polysorbate 20, sodium bicarbonate, patent blue V dye (E131), quinoline yellow (E104), purified water.

Tantum Verde Spray

Active substance (in 1 dose): benzydamine hydrochloride
255 mcg (150 mg in 100 ml).

Inactive substances: glycerol, ethanol, menthol flavor, methyl parahydroxybenzoate, saccharin, polysorbate 20, sodium bicarbonate, purified water.

Additionally:

Do not allow spray to get into eyes. If a burning sensation occurs when using Tantum Verde, the solution must be diluted with water before use (2 times) in a graduated cap. Do not dilute the solution contained in the vial with water!

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Dear doctors!

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NSAIDs for topical use in ENT practice and dentistry

Active substance

Release form, composition and packaging

◊ Spray for local use dosed in the form of a colorless transparent liquid with a characteristic mint odor.

Excipients: ethanol 96% - 10 ml, glycerol - 5 g, methyl parahydroxybenzoate - 0.1 g, menthol flavor (flavor additive) - 0.03 g, saccharin - 0.024 g, - 0.011 g, polysorbate 20 - 0.005 g, purified water - q.s. up to 100 ml.

30 ml (176 doses) - polyethylene bottles with a pump and a pressure device with a folding cannula (1) - cardboard packs.

pharmachologic effect

NSAIDs for topical use, belongs to the group of indazoles. It has an anti-inflammatory and local anesthetic effect, has an antiseptic effect against a wide range of microorganisms.

The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis.

Benzydamine has an antibacterial effect due to the rapid penetration of microorganisms through the membranes, followed by damage to cellular structures, disruption of metabolic processes and cell lysis.

Possesses antifungal action for Candida albicans. Causes structural modifications of the cell wall of fungi and metabolic chains of mycetes and thus prevents their reproduction. This property was the basis for the use of benzydamine in inflammatory processes in the oral cavity, incl. infectious etiology.

Pharmacokinetics

When applied topically, the drug is well absorbed through the mucous membranes and penetrates into inflamed tissues, is found in the blood in an amount insufficient to obtain systemic effects.

Benzydamine is excreted mainly by the kidneys as inactive metabolites or conjugation products.

Indications

Symptomatic therapy of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (of various etiologies):

- gingivitis, glossitis, stomatitis (including after radiation and chemotherapy);

- pharyngitis, laryngitis, tonsillitis;

- candidiasis of the oral mucosa (as part of combination therapy);

- calculous inflammation of the salivary glands;

- after surgical interventions and injuries (tonsillectomy, jaw fractures);

- after treatment and extraction of teeth;

- periodontitis.

In infectious and inflammatory diseases requiring systemic treatment should be used as part of combination therapy.

Contraindications

- children's age up to 3 years;

- hypersensitivity to benzydamine or other components of the drug.

FROM caution drug should be used for hypersensitivity to or other NSAIDs; bronchial asthma(including in history).

Dosage

The drug is used topically, after meals.

1 dose (1 injection) corresponds to 0.255 mg of benzydamine.

Adults (including elderly patients) and children over 12 years of age appoint 4-8 injections 2-6 times / day; children aged 6 to 12 years- 4 injections 2-6 times / day; children aged 3 to 6 years- 1 injection for every 4 kg of body weight, but not more than 4 injections (maximum single dose) 2-6 times / day. Do not exceed the recommended dose.

The duration of treatment should not exceed 7 days. If after treatment within 7 days there is no improvement or new symptoms appear, the patient should consult a doctor.

Instructions for use

1. Rotate the cannula (tube white color) in a position vertical to the vial.

2. Insert the cannula into the mouth and direct it to the inflamed places in the mouth or throat.

3. Press the dosing pump on the top of the vial as many times as the prescribed doses. 1 press corresponds to 1 dose. It is necessary to hold your breath during injection.

Side effects

Classification of the frequency of development side effects WHO: very often (≥1/10); often (from ≥1/100 to<1/10); нечасто (от ≥1/1000 до <1/100); редко (от ≥1/10 000 до <1/1000); очень редко (<1/10 000); частота неизвестна (не может быть оценена на основании имеющихся данных).

Within each group, adverse effects are presented in order of decreasing severity.

Local reactions: rarely - dry mouth, burning sensation in the oral cavity; the frequency is unknown - a feeling of numbness in the oral cavity.

Allergic reactions: infrequently - photosensitivity; rarely - hypersensitivity reactions, pruritus; very rarely - angioedema, laryngospasm; frequency unknown - anaphylactic reactions.

If any of the side effects indicated in the instructions are aggravated or any other side effects not indicated in the instructions are noted, the patient should immediately inform the doctor about this.

Overdose

At present, no cases of overdose of Tantum Verde have been reported. When using the drug in accordance with the instructions for use, an overdose is unlikely.

Symptoms: if the drug is accidentally swallowed, the following symptoms are possible - vomiting, abdominal cramps, anxiety, fear, hallucinations, convulsions, ataxia, fever, tachycardia, respiratory depression.

Treatment: conducting symptomatic therapy; induce vomiting or gastric lavage using a stomach tube (under medical supervision); it is necessary to provide medical supervision, maintenance therapy and necessary hydration. The antidote is unknown.

drug interaction

Interaction studies with other medicinal products have not been conducted.

special instructions

When using the drug Tantum Verde, hypersensitivity reactions may develop. In this case, it is recommended to stop treatment and consult a doctor to prescribe appropriate therapy.

In a limited number of patients, the presence of sores in the throat and mouth may indicate the presence of a more serious pathology. If the symptoms persist for more than 3 days, the patient should consult a doctor.

Tantum Verde should be used with caution in patients with a history of possible development of bronchospasm while taking the drug.

Tantum Verde contains parahydroxybenzoates, which may cause allergic reactions.

Influence on the ability to drive vehicles and control mechanisms

The drug does not affect the ability to drive vehicles and work with mechanisms.

The green tablet contains 3 mg of the active ingredient . Additional substances: mint flavor, racementol, isomaltose, quinoline yellow dye, citric acid monohydrate, , dye indigo carmine.

Spray composition: in 1 dose - 255 mcg benzydamine hydrochloride . Additional Ingredients: N Hydrogen Carbonate, Menthol Flavor, Methyl Parahydroxybenzoate, , water, ethanol 96%.

Solution: in 100 ml - 150 mg benzydamine . Additional components: proprietary blue dye, yellow quinoline dye, glycerol, water, polysorbate-20, saccharin, menthol flavor.

Release form

Tablets

Green, translucent tablets intended for resorption, have a square shape. There is a slight indentation in the center. Characterized by a specific lemon-mint smell. Each tablet is packed in paraffin paper. In a pack of cardboard there are 10 tablets packed in a two-layer aluminum foil.

Spray Tantum Verde

Clear liquid with a peculiar minty smell. Produced in polyethylene bottles with a pressure device with a cannula and a pump. In a pack of cardboard 1 bottle of 30 ml, designed for 176 doses, and instructions from the manufacturer.

Solution

Greenish, almost transparent solution of 0.15% concentration. Available in 120 ml glass bottles. Additionally, the kit comes with a graduated glass of propylene with a volume of 15 ml (or 30). In a pack of cardboard 1 bottle with instructions.

pharmachologic effect

Benzydamine refers to indazolam and is a non-steroidal drug with anti-inflammatory activity. The active substance is characterized antiseptic and analgesic action .

The antiseptic effect is manifested in relation to most microorganisms. The main mechanism of action is aimed at inhibiting the synthesis process, at stabilizing cell membranes.

Antimicrobial and antibacterial effect is achieved due to the instant penetration of the active substance through microbial membranes and further damage to cell structures. Additionally, the course of most metabolic processes is disrupted and a logical lysis of the microbial cell occurs.

In a relationship candida albicans pronounced antifungal effect . The active substance damages the metabolic chains of mycetes, changes the modification of the fungal cell wall, which prevents further reproduction. This effect allows the use of benzydamine in inflammatory diseases of the mouth of infectious origin.

Pharmacodynamics and pharmacokinetics

Benzydamine as an active ingredient penetrates deeply into inflamed tissues due to good absorption. Excretion is carried out by the renal system, part of the conjugates and metabolites is excreted through the intestines.

Indications for use

Diseases of the oral cavity of inflammatory genesis of any etiology:

• (with complex treatment) ;
• gingivitis ;
• after tooth extraction, treatment;
• after traumatic injuries, surgical interventions (fractured jaw, tonsillectomy and others);
• inflammatory process in the salivary glands of a calculous nature.

The drug can be used for anti-inflammatory purposes and for pain relief.

Contraindications

• (for tablet form);
• individual hypersensitivity.

Age restrictions on the use of a 0.15% solution - up to 12 years, tablets - up to 3 years.

Side effects

• burning sensation in the mouth;
• numbness;
• dry mouth;
• laryngospasm;
• skin rashes.

Instructions for Tantum Verde (Method and dosage)

Spray Tantum Verde, instructions for use

Dosed spray 0.255 mg - 1 dose; applied every 90-180 minutes for 4-8 injections, doses. Spray for children 6-12 years old is prescribed every 90-180 minutes for 4 injections, doses; 3-6 years - 1 to 4 doses.

Tablets Tantum Verde, instructions for use

Tablets are applied topically by resorption. Scheme: one tablet 3-4 times a day. It is recommended to keep lozenges in the mouth for as long as possible for greater
efficiency.

Solution

Using a measuring cup, the required dose is measured, the treatment is carried out 2-3 times a day using 15 ml of the solution. In inflammatory processes, it is recommended to use an undiluted solution.

For hygienic, daily treatment dilution 1:1 (15 ml of water and 15 ml of solution are mixed in the enclosed measuring cup).

Overdose

Thematic and medical literature does not contain a description of the clinical symptoms of an overdose.

Interaction

Significant interactions are not described.

Terms of sale

Non-prescription leave Tantum Verde.

Storage conditions

The storage temperature limit from the manufacturer is up to 25 degrees. Protect the solution from the aggressive effects of sunlight.

Best before date

Spray, solution and lozenges can be stored for 4 years without loss of effectiveness.

special instructions

When burning sensations appear in the application area, dilution of the solution is recommended: the water level is brought to the level of the risk on a special graduated glass attached to the package. Dilution 1:2.

It is unacceptable to get the spray when spraying into the eyes. The drug does not affect the ability to drive a motor vehicle and machines.

Which is better: Tantum Verde or Hexoral?

Both drugs are prescribed for inflammatory diseases of the mouth to suppress the microbial flora.

Spray Tantum Verde can be used only after consultation with your doctor.

Reviews about Tantum Verde

Reviews about the Tantum Verde spray from doctors and patients are positive: the medication relieves the unpleasant symptoms of oral diseases, reduces the severity of the pain syndrome, helps to suppress the microbial flora and speed up recovery.

Parents on thematic forums share their experience of using the medication, leaving positive feedback about Tantum Verde for children.

Price Tantum Verde, where to buy

You can buy medication at a pharmacy. The cost depends on the dosage form, the region of sale, the pharmacy chain.

The price of Tantum Verde spray in Russia is 300 rubles. The price of lozenges for resorption is 200 rubles. Spray Tantum Verde for children costs 300 rubles.

• Internet pharmacies in Russia Russia
• Internet pharmacies of Ukraine Ukraine
• Internet pharmacies of Kazakhstan Kazakhstan

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