Hexicon rectal application. The drug Hexicon is an effective remedy for the treatment of genitourinary infections.

In this article, you can read the instructions for use medicinal product Hexicon. Reviews of site visitors - consumers are presented this medicine, as well as the opinions of doctors of specialists on the use of Hexicon in their practice. We kindly ask you to actively add your reviews about the drug: the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Hexicon in the presence of existing structural analogues. Use for the treatment of infections, including sexually transmitted infections, candidiasis (thrush) and other vaginitis in adults, children, as well as during pregnancy and lactation.

Hexicon- antiseptic preparation for external and local application. The main active ingredient is chlorhexidine bigluconate.

Active against gram-positive and gram-negative bacteria - Treponema spp., Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis; protozoa - Trichomonas spp.; viruses - Herpes simplex type 2.

The gel, when applied to the skin and mucous membranes, has a bactericidal effect.

Retains activity (albeit somewhat reduced) in the presence of blood, pus.

Pharmacokinetics

Practically not absorbed from the gastrointestinal tract. It is excreted mainly with feces (90%), less than 1% is excreted in the urine.

Indications

Hexicon solution for external use:

  • prevention of sexually transmitted infections (including gonorrhea, syphilis, trichomoniasis, chlamydia, ureaplasmosis, genital herpes);
  • treatment of urethritis and urethroprostatitis (as part of complex therapy);
  • disinfection of purulent wounds, infected burn surfaces;
  • treatment of infections of the skin and mucous membranes (in surgery, obstetrics and gynecology, urology);
  • treatment of infections of the skin and mucous membranes (in surgery, obstetrics and gynecology, urology),
  • in dentistry for rinsing and irrigation with gingivitis, stomatitis, aphthae, periodontitis, alveolitis.

Hexicon gel for local and external use:

  • in gynecology: treatment of vulvovaginitis;
  • in urology: treatment of balanitis, balanoposthitis;
  • in dentistry: treatment of gingivitis, stomatitis, aft, periodontitis, alveolitis;
  • in dermatology: treatment of skin infections (including pyoderma, impetigo, paronychia, panaritium, diaper rash).

Release form

Candles vaginal Hexicon D 16 mg.

Gel (ointment) for local and external use 0.5%.

Solution for external use 0.05%.

Tablets 16 mg.

Instructions for use and dosing regimen

Candles are vaginal. For treatment - 1 suppository 2 times a day. The course of treatment is 7-10 days, if necessary, it is possible to extend the course of treatment up to 20 days. For the prevention of sexually transmitted diseases - 1 suppository, no later than 2 hours after sexual intercourse.

Solution for external use. For the prevention of sexually transmitted infections, Hexicon is effective if it is applied no later than 2 hours after sexual intercourse.

Using a nozzle, enter the contents of the vial into the urethra for men (2-3 ml), women (1-2 ml) and into the vagina (5-10 ml) and hold for 2-3 minutes.

Treat the skin of the inner surfaces of the thighs, pubis, genitals with a solution. After the procedure, you should not urinate for 2 hours.

Complex treatment of urethritis and urethroprostatitis is carried out by injecting 2-3 ml of Hexicon solution into the urethra 1-2 times a day, the course is 10 days. Procedures are prescribed every other day.

Hexicon solution is also used in the form of irrigations, rinses and applications - 5-10 ml of the solution is applied to the affected surface of the skin or mucous membranes with an exposure of 1-3 minutes 2-3 times a day (on a swab or by irrigation).

For stomatitis, gingivitis, periodontitis, rinsing is recommended oral cavity 5-10 ml of the drug, 3-4 times a day.

Side effect

  • allergic reactions and itching, passing after discontinuation of the drug;
  • dry skin;
  • dermatitis;
  • stickiness of the skin of the hands (within 3-5 minutes);
  • photosensitivity;
  • staining of tooth enamel;
  • deposition of tartar;
  • taste disorder.

Contraindications

  • dermatitis;
  • allergic reactions.
  • hypersensitivity to the components of the drug.

The drug should be used with caution in childhood.

Use during pregnancy and lactation

The drug Hexicon in the form of a solution for local and external use is not contraindicated for use during pregnancy and lactation.

special instructions

When applied externally and locally, the drug should be avoided getting inside the wound in patients with open craniocerebral trauma, injuries spinal cord, perforation eardrum.

If the solution comes into contact with the mucous membranes of the eyes, they should be rinsed quickly and thoroughly with water.

The ingress of hypochlorite bleaching agents on fabrics that have previously been in contact with preparations containing chlorhexidine (the active ingredient in Hexicon) may contribute to the appearance of brown spots on them.

The bactericidal effect increases with increasing temperature. At temperatures above 100 °C, the preparation partially decomposes.

drug interaction

Hexicon is incompatible with detergents containing an anionic group (including saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps. The presence of soap can inactivate chlorhexidine, so soap residue must be thoroughly washed off before using the drug.

Ethanol (alcohol) enhances the effectiveness of the drug.

Analogues of the drug Hexicon

Structural analogues for the active substance:

  • Amident;
  • Hexicon D;
  • Hibiscrab;
  • Cathejel C;
  • Plivasept;
  • Chlorhexidine;
  • Chlorhexidine bigluconate;
  • Chlorhexidine Zhifrer;
  • Tsiteal.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.

Hexicon - a drug (candles), belongs to the category of antiseptics and antimicrobials for the treatment of gynecological diseases. Important Features medicines from the instructions for use:

  • During pregnancy: you can
  • When breastfeeding: you can
  • In childhood: contraindicated

Package

Compound

The composition of one Hexicon suppository includes 16 mg of Chlorhexidini bigluconas, as well as a polyethylene oxide base (polyethylene oxide 1500 / Polyaethylenoxydum 1500, polyethylene oxide 400 / Polyaethylenoxydum 400).

The Hexicon D suppository contains 8 mg of Chlorhexidini bigluconas, as well as a polyethylene oxide base (polyethylene oxide 1500 / Polyaethylenoxydum 1500, polyethylene oxide 400 / Polyaethylenoxydum 400).

The solution for external use contains 0.5 mg of Chlorhexidini bigluconas solution at a concentration of 20%, purified water (Aqua purificata).

One hundred grams of gel contains 0.5 g of Chlorhexidini bigluconas and auxiliary components: Cremophor - RH 40 (Cremophor RH 40), Poloxamer 407 (Poloxamerum 407), purified water (Aqua purificata).

One vaginal tablet of Hexicon contains 16 mg of Chlorhexidini bigluconas (as a solution of Chlorhexidini bigluconas with a concentration of 20%) and auxiliary components: microcrystalline cellulose (Cellulosum microcrystallisatum), pregelatinized corn starch (Amylum maidis), low molecular weight povidone (Povidone), stearic acid (Acidum stearicum), lactose monohydrate (Lactose monohydrate).

Release form

The manufacturer produces the drug in the form of:

  • vaginal suppositories 8 and 16 mg;
  • solution;
  • gel;
  • vaginal tablets 16 mg.

pharmachologic effect

Hexicon belongs to the pharmacotherapeutic group of drugs with antiseptic and disinfectant action. Entering into interaction with the structures of the microbial cell, it disrupts vital activity, inhibits the development and provokes the death of pathogenic microflora.

The use of various dosage forms of Hexicon in gynecological practice allows not only to successfully fight pathogenic microorganisms, but also to prevent infectious diseases transmitted by PC.

Pharmacodynamics and pharmacokinetics

Chlorhexidine, which is part of Hexicon as an active ingredient, is a strong disinfectant, which is sensitive to a wide range of microorganisms, including Gram (+) and Gram (-) bacteria, protozoa, herpesviruses.

Hexicon is effective against:

  • gonococci (Neisseria gonorrhoeae);
  • pale treponema (Treponema pallidum);
  • chlamydia (Chlamydia spp.);
  • gardnerella (Gardnerella vaginalis);
  • ureaplasma (Ureaplasma spp.);
  • bacteroides fragilis (Bacteroides fragilis);
  • Trichomonas (Trichomonas vaginalis);
  • herpesvirus type II (HSV-2).

Weak sensitivity to the drug is characterized by individual strains of Pseudomonas (Psevdomonas spp.) and Proteus (Proteus spp.). Resistant to its effects are viruses, fungi, bacterial spores, acid-resistant bacteria.

Thanks to chlorhexidine, which is part of Hexicon, the drug has a number of advantages over other antimicrobial and antiseptic agents. He:

  • does not violate the natural microflora of the female genital tract and does not affect the activity of lactobacilli;
  • does not cause addiction and resistance to its action in microorganisms sensitive to it (even with repeated use);
  • approved for use in the treatment of pregnant and lactating women;
  • retains (albeit to a lesser extent) activity in the presence of spotting and pus.

The effectiveness of suppositories is also ensured by the features of their constituent polyethylene oxide 1500 (Polyaethylenoxydum 1500) and polyethylene oxide 400 (Polyaethylenoxydum 400). These substances provide a more uniform distribution of the active substance over the surface of the mucous membrane and its deeper penetration into the tissues.

In addition, the polyethylene oxide base dehydrates pathogenic microorganisms and cleanses the mucosa from the products of their vital activity accumulating on it.

Hexicon vaginal tablets have been developed as an alternative to suppositories. For some women, they are somewhat more convenient than suppositories because they do not increase the volume of secretions and therefore do not involve the use additional funds hygiene.

Practically not absorbed from the gastrointestinal tract, as well as through the skin and mucous membranes when applied topically. Systemic absorption when using Hexicon tablets intravaginally is extremely negligible.

In case of inadvertent ingestion of 0.3 g Cmax is reached after half an hour and is 0.206 µg / l.

The drug is eliminated from the body mainly with the contents of the intestine (90%), less than 1% is excreted by the kidneys.

Indications for use

Candles Hexicon - what are they from?

Hexicon suppositories are indicated for the prevention of sexually transmitted infectious diseases caused by the activity of microflora sensitive to the action of the drug, for the treatment of inflammation of the genital organs in women, for the prevention of the development of the inflammatory process and infection of the genital tract before childbirth, gynecological operations, abortion procedure, intrauterine research, etc. .d..

Indications for the use of Hexicon D suppositories are children's gynecological diseases.

Indications for the use of solution, gel and vaginal tablets are the same as for suppositories.

Additional indications for the use of the solution

The solution is used as a disinfectant for the treatment of purulent wounds and infected burns. In gynecology, surgery and urology, it is used to treat infectious lesions of the skin and mucous membranes.

Dentists prescribe rinses with Hexicon for aphthous stomatitis, gingivitis, inflammatory lesions of periodontal tissues and terminal respiratory tract.

Additional indications for the use of the gel

Hexicon gel is used to treat inflammatory diseases in gynecology, dentistry and urology. In addition, they are treated with infected areas of the skin.

Contraindications

Contraindications to the appointment of Hexicon are hypersensitivity to its components.

An additional contraindication for the solution is dermatitis.

Gel and suppositories are used with caution in the treatment of children. The optimal dosage form for a child is Hexicon D suppositories.

Side effects

The most common side effects of suppositories are allergic reactions, itching and burning in the vagina. These symptoms do not require specific treatment and disappear on their own after stopping the course of treatment.

Hexicon D vaginal suppositories provoke unwanted side effects in less than 0.1% of cases.

Undesirable reactions to the use of the solution are also extremely rare. As a rule, they are expressed in the form of allergy symptoms and itching, which disappear after the treatment is stopped.

For some, the Hexicon solution causes dry skin of the hands, stickiness of the hands (usually no more than three to five minutes), dermatitis, and photosensitivity. Rinses of the oral cavity with them lead to staining of tooth enamel, deposition of tartar, taste disturbances. Gel can also provoke similar phenomena.

Instructions for use Hexicon

Candles Hexicon: instructions for use

Candles are intended for intravaginal use.

AT medicinal purposes twice a day for 7-10 days, one suppository is administered intravaginally. If necessary, the course of treatment is repeated after 20 days.

To prevent sexually transmitted diseases, it is recommended to enter one suppository no later than two hours after unprotected intercourse.

Instructions for the use of Hexicon D are similar to the instructions for the use of 16 mg suppositories.

Gel Hexicon: instructions for use

For the treatment of inflammatory urological and gynecological diseases, the gel should be applied to the affected surfaces twice a day. The duration of treatment can vary from 7 to 10 days.

Infectious dermatological diseases are treated by thinly applying the gel to the affected surfaces two or three times a day. How long the treatment will be depends on the clinical situation.

In dental practice, the ointment is used in the form of applications with a multiplicity of 2-3 times a day. The duration of one procedure is from one to three minutes. The duration of the course is determined depending on the clinical situation.

Instructions for use of the solution

The solution is used externally and topically in the form of applications, irrigations and rinses. For one procedure, it is necessary to apply on the affected surface of the skin or mucous membranes from five to ten milliliters of the product with an exposure of one to three minutes 2 or 3 times a day (the solution can be applied on a swab or by irrigation).

For the prevention of infections that are transmitted by PP, it is advisable to use Hexicon if the procedure is carried out no later than two hours after sexual contact.

Using a nozzle, the liquid contained in the vial is injected into the urethra (for both women and men) or into the vagina. Dose for injection into the urethra for men - from 2 to 3 ml, for women - 1 or 2 ml. From 5 to 10 ml of solution is injected into the vagina. The nozzle is delayed for 2-3 minutes.

The solution should also treat the genitals and skin covering inner thighs and pubis. It is not recommended to urinate within two hours after the procedure.

With inflammation of the urethra (including complicated by prostatitis), it is assumed complex therapy, which is supplemented by injection for ten days once or twice a day into the urethra of a solution in a volume equal to 2-3 ml (it is recommended to carry out the procedure every other day).

In diseases of the oral cavity, rinsing with a solution of the drug is prescribed. Multiplicity of procedures - 3-4 per day. The amount of solution required for one procedure is from 5 to 10 ml.

Instructions for use of vaginal tablets

Before use, the tablet is moistened in water and injected into the vagina. The daily dose, depending on the diagnosis, is 1 or 2 tablets. Treatment is carried out within 7-10 days.

To prevent infections that are transmitted by PP, the tablet, like suppositories, is recommended to be administered within two hours after unprotected intercourse.

Overdose

Since the drug is practically not absorbed from the gastrointestinal tract and is not absorbed when applied topically through the skin and mucous membranes, the likelihood of an overdose is considered unlikely.

To date, there is no information on cases of overdose with Hexicon.

Interaction

The effectiveness of the drug is enhanced by simultaneous use with ethanol.

Hexicon should not be used with intravaginally administered preparations containing iodine.

Sanitation of the external genital organs does not affect the effectiveness and tolerability of suppositories, since they are applied intravaginally.

Pharmaceutically incompatible with anionic detergents (saponins, Sodium lauryl sulfate, Sodium carboxy methyl cellulose) and soap. Chlorhexidine is inactivated in the presence of soap, therefore, before using the drug, it is necessary to thoroughly wash off soap residues from the skin and mucous membranes.

It is allowed to combine Hexicon with preparations containing a cationic group.

Terms of sale

OTC

Storage conditions

In a dry place, at a temperature not higher than 25°C for tablets, solution, suppositories and not higher than 20°C for gel.

Best before date

special instructions

Hygiene procedures do not affect the efficacy and tolerability of vaginal tablets and suppositories, since the drug in these dosage forms is administered intravaginally.

When using the solution in patients with head and spinal cord injuries, as well as in patients with perforation of the tympanic membrane, its entry into the wound should be avoided.

If the solution accidentally gets on the mucous membranes of the eye, it is recommended to rinse them quickly and very well with water.

The contact of bleaching agents containing sodium hypochlorite in their composition on clothes that have previously been in contact with chlorhexidine preparations provokes the formation of brown spots on them.

Increasing the temperature of the solution causes an increase in its bactericidal action. However, at temperatures exceeding 100°C, there is a partial decomposition of the drug.

How to enter candles?

To prevent leakage of the contents after the introduction of the suppository, the woman should lie on the bed, spreading her bent in knee joints legs. The candle is inserted as deep as possible into the vagina with the index finger (if possible to the depth of the finger).

If the suppository is not inserted deep enough, it may fall out after the woman gets up before it dissolves.

The principle of operation of Hexicon is similar to the principle of vaginal baths. A feature of these candles is that they are driven several times a day, as a result of which the amount of discharge increases significantly. Given this, during the treatment period, daily pads should be changed as often as possible.

Another feature of suppositories is that before their introduction there is no need to prescribe additional sanitation of the vagina or douching, which makes their use more convenient than other vaginal suppositories.

An important recommendation for the period of treatment is the exclusion of sexual intercourse. If therapy is carried out against the background of regular sexual activity, then positive result will not be reached. There remains a risk of re-infection and as a result, it may be necessary to prescribe drugs not only local, but also systemic.

The use of Hexicon during menstruation

Quite often, questions arise whether it is possible to use suppositories during menstruation and whether it is allowed to be treated with vaginal tablets during menstruation.

The instructions for Hexicon indicate that the use of suppositories and tablets during menstruation is permissible. This is due to the fact that active substance the drug retains (albeit to a lesser extent) pharmacological properties in the presence of pus, spotting and other biological fluids.

Hexicon's analogs

Analogues in composition for Hexicon in the form of a solution and gel are Amident (solution for topical use) and Chlorhexidine in the form of an alcohol solution, solution, concentrate for preparing a solution, spray.

According to the mechanism of action, Bepanten (cream), Depantol (cream), Lavasept (concentrate for solution preparation), Tsiteal (solution) are the closest.

Candles and tablets Hexicon have a similar composition with, respectively, suppositories and tablets Chlorhexidine. Similar drugs according to the mechanism of action for suppositories are Betadine (suppositories), Giposol (aerosol), Yodovidone (candles), Yodoxide (candles), Macmirror (cream, capsules, tablets, suppositories), vaginal suppositories with Trichomonacid, vaginal suppositories with eucalimine, Trichomonacid (tablets), Furazolidone (powder, tablets, granules for suspension preparation), Vagiflor (capsules), Povidone-Iodine (suppositories), Dafnedzhin (cream), Lactoginal (capsules).

Hexicon during pregnancy

All dosage forms produced under the Hexicon brand, with the exception of vaginal tablets, are allowed to be prescribed during pregnancy and lactation. The instructions for Hexicon suppositories during pregnancy and lactation indicate that this remedy is considered not only effective, but also safe for both mother and child.

As for vaginal tablets, their use is possible if the benefit to the mother outweighs the risk to the fetus.

Candles Hexicon during pregnancy are one of the most commonly prescribed drugs for the treatment and prevention of gynecological diseases. The safety of the drug is ensured by its local effect and is confirmed by many years of experience in use.

Acting locally, its active substance practically does not enter the systemic circulation and, thus, does not pose a threat to the normal development of the child. Therefore, candles are allowed to be used at all stages of pregnancy.

Hexicon effectively affects pathogenic microorganisms that cause female diseases, but it does not provoke any violations of the vagina's own microflora.

In the 1st and 2nd trimesters, this allows you to prescribe a remedy for the prevention of infectious diseases transmitted by PP (syphilis, ureaplasmosis, trichomoniasis, gonorrhea, chlamydia, genital herpes), and for the treatment of vaginitis, colpitis, bacterial vaginosis, endo- and exocervicitis.

In the 3rd trimester (and, in particular, before childbirth), Hexicon is prescribed to prevent the development of infectious and inflammatory processes immediately during and after childbirth.

Candles are also used for cervical erosion. It is advisable to prescribe them in cases where the cause of ulceration is the activity of pathogens transmitted by PP, or inflammatory “female” pathologies.

During pregnancy, Hexicon is most often prescribed for bacterial vaginosis, when the vagina is dominated by pathogenic bacteria, and the number of lactic acid bacteria (lactobacilli) is reduced or these bacteria are completely absent.

A decrease in the number of lactic acid bacteria in a pregnant woman against the background of bacterial vaginosis can cause the development of vulvovaginal candidiasis (or, in other words, thrush).

As practice shows, every year there are more and more cases of a combination of candidiasis and bacterial vaginosis. For this reason, it is widely believed that Hexicon suppositories are effective for thrush.

Candles Hexicon from thrush

A yeast-like fungus of the genus Candida provokes the development of candidal vulvovaginitis, which, like many viruses, bacterial spores and acid-resistant varieties of bacteria, is immune to the effects of chlorhexidine.

So why are these suppositories prescribed during pregnancy from thrush? The thing is that the cause of thrush is the uncontrolled growth of Candida fungus colonies, which can be triggered, among other things, by the activity of infectious pathogens - gonococci, Trichomonas and other bacteria and protozoa.

In such cases, when the infection is of a mixed, fungal-bacterial nature, the expediency of using Hexicon is due to its ability to effectively remove signs of inflammation, reduce tissue swelling and significantly reduce the severity of pain.

To combat the overproliferating fungus, which is the direct source of the disease, antimycotic drugs are used in the form of gels, creams and vaginal tablets (for example, Fluconazole, Pimafucin or Clotrimazole).

It is important to remember that self-medication - especially during pregnancy - is unacceptable, and Hexicon from thrush is prescribed only on the basis of a medical examination and passing all the necessary tests.

Thus, Hexicon suppositories are an effective and safe antibacterial agent for local application, however, for the treatment of candidiasis, it is recommended to choose drugs that can actively suppress the main culprit of the disease.

A prerequisite for successful treatment is compliance with the requirements of personal hygiene and - in some cases - the preparation of a special dietary menu that involves limiting the amount of food with a high content of carbohydrates in it, and introducing a sufficient amount of fermented milk products into the diet.

Content

Gel, solution, tablets or suppositories Hexicon are prescribed by a gynecologist for the treatment of inflammation of the genital organs in women. All forms of release of the drug belong to the category of broad-spectrum antiseptics. They are used for topical treatment of sexually transmitted infections, as well as some childhood diseases in gynecology. The indication for use is preventive actions of these pathologies, especially before childbirth or operations.

Instructions for use Hexicon

The drug is based on a substance that has activity against gram-negative and gram-positive forms of bacteria. The drug has established itself as an excellent antiseptic against infections of the genital tract. The effectiveness of the active substance is somewhat reduced in the presence of pus or blood. The peculiarity of the drug is that it does not affect lactobacilli, which make up normal microflora vagina.

Composition and form of release

Each release form contains the antiseptic chlorhexidine bigluconate as an active ingredient. Only the concentration of this component differs. Its presence is due to the properties of the antiseptic drug. The table shows the composition of the drug more clearly:

Variety of release form

The concentration of the active ingredient

Excipients

a brief description of

Hexicon candles

8 or 16 mg in 1 piece

Polyethylene oxide 400, polyethylene oxide 1500,

They have a torpedo shape, white or yellowish color, a slight marbling of the surface is allowed. Sold in cardboard boxes of 2 contour cells with 5 suppositories

Purified water

It is a colorless, transparent or slightly opalescent, odorless liquid. Sold in polyethylene bottles of different sizes

0.5 g in 100 g

Cremophor-RH 40, poloxamer 407, purified water

Colorless, transparent, available in aluminum tubes

Hexicon vaginal tablets

16 mg in 1 piece

Microcrystalline cellulose, pregelatinized corn starch, lactose monohydrate, low molecular weight povidone, stearic acid

Biconvex, color - white or yellowish, slight marbling is possible on the surface, oblong in shape.

Pharmacodynamics and pharmacokinetics

Chlorhexidine, which is the basis of all forms of release of the drug, exhibits a strong disinfecting effect. It is sensitive to a wide range of microorganisms: herpesviruses, different types bacteria, protozoa. Their list includes:

  • fragilis bacteria;
  • gonococci;
  • ureaplasma;
  • Trichomonas;
  • chlamydia;
  • pale treponema;
  • gardnerella;
  • herpes virus type 2.

Some strains of Pseudomonas and Proteus are less sensitive to chlorhexidine, and bacterial spores, viruses, fungi, and acid-resistant bacteria are completely resistant. Active substance their digestive tract is practically not absorbed, as well as through the skin when applied topically. When administered intravaginally, systemic absorption is negligible. If you accidentally swallow a tablet, then its half-life will be 0.206 μg / l. The substance is excreted with feces from the intestines. The kidneys excrete less than 1% chlorhexidine.

What does Hexicon treat?

Suppositories and solution are used to treat and prevent infections that are sexually transmitted and develop after exposure to drug-sensitive microflora. Additionally, the list of indications for use includes:

  • inflammation of the genital organs, vaginal mucosa, uterus and cervix;
  • prevention of inflammatory processes before childbirth, abortion procedure and gynecological operations;
  • treatment of infected burns and purulent wounds;
  • infections of the skin and mucous membranes;
  • aphthous stomatitis;
  • gingivitis;
  • inflammatory lesions of periodontal tissues.

How to take Hexicon

The release forms of this antiseptic differ in instructions for use. Suppositories and vaginal tablets are indicated for insertion directly into the vagina. The gel and solution can be used topically for local skin lesions. The course of treatment varies depending on the disease that requires treatment. Men can also use this medication, but only in the form of a gel or solution.

Candles Hexicon

This release form is intended for intravaginal use. For 7-10 days, you need to enter 1 suppository daily. If necessary, resort to a second course, but not earlier than 20 days after the end of the first therapy. To prevent the development of sexually transmitted diseases, the introduction is shown vaginal suppositories no later than 2 hours after intercourse without a condom. The scheme for using Hexicon D candles is similar.

Vaginal suppositories are very important to enter correctly so that the contents do not leak out of the vagina. To do this, a woman needs:

  • lie on the bed, bend your legs and spread apart;
  • insert the suppository into the vagina with the index finger to its depth;
  • lie down for another 5-7 minutes, so that after taking a vertical position, the candle does not fall out.

According to the instructions for use, treatment with vaginal tablets or suppositories can also be carried out during menstruation. Though active ingredient and slightly reduces its effectiveness in the presence of pus, spotting or other biological fluids, therapy still brings a positive result than in its absence.

Hexicon tablets

Depending on the diagnosis, the daily dosage of the drug may be 1 or 2 tablets. Before the procedure, it must be moistened with water, and then inserted into the vagina. It is better to do this in a prone position. In order to prevent sexually transmitted infections, the administration of 1 tablet is indicated within 2 hours after unprotected intercourse.

Solution

The solution has a wider range of applications. It is used for irrigation, rinsing and local applications. For one procedure, about 5-10 ml of a solution is needed, which is applied to the affected skin or vaginal mucosa. The focus can simply be irrigated with a liquid, or you can first moisten a swab in it, which is then applied to the sore spot. The procedure is repeated 2-3 times during the day. Other solution treatment options:

  1. For diseases of the oral cavity. Showing 3-4 rinses per day 5-10 ml of solution.
  2. For the prevention of sexual infections. Using a nozzle, the solution is injected into the vagina no later than 2 hours after unprotected intercourse. The dosage is 5-10 ml. The nozzle of the vial is held inside for 2-3 minutes. The solution needs to treat the skin on the inner thighs and genitals. Urination is prohibited for about 2 hours after the procedure.

Hexicon gel

This form of release is used externally for application to the mucous membranes or skin. For each disease there is a specific treatment regimen:

  1. Inflammatory gynecological diseases. A thin layer of the gel is applied to the affected areas 2 times a day. The course of therapy can vary from 7 to 10 days.
  2. Dermatological infections. Hexicon ointment is applied to the lesions 2-3 times a day. The duration of the procedures depends on the disease.
  3. Dental diseases. The gel is used for 2-3 applications per day. One procedure lasts 1-3 minutes. It is necessary to continue treatment depending on the clinical situation.

special instructions

Hygiene procedures do not affect the effectiveness of therapy with suppositories or vaginal tablets. It is important to avoid getting the solution inside the wound in patients with trauma to the brain and spinal cord or perforation of the tympanic membrane. In case of accidental contact with the mucous membrane of the eye, immediate rinsing is required. At the time of treatment, it is recommended to exclude sexual intercourse. Regular sex life reduces the effectiveness of therapy. The result can be re-infection, which will require the use of not only local preparations but also systemic.

During pregnancy

Each dosage form antiseptic is approved for use during pregnancy and lactation. It is not only effective during this period, but also completely safe for both the mother and the fetus. The exception is vaginal tablets. They are used only if the expected benefit from potential harm. In the 1st and 2nd trimester of pregnancy, indications for use are:

  • ureaplasmos;
  • gonorrhea;
  • chlamydia;
  • trichomoniasis;
  • genital herpes;
  • exocervicitis;
  • bacterial vaginosis;
  • colpitis;
  • vaginitis.

Although the drug is ineffective against Candida fungi, it is still prescribed for the treatment of thrush in pregnant women. The reason is that more often a fungal infection during this period in women is provoked by gonococci, Trichomonas and other bacteria. With a mixed fungal-bacterial nature of thrush, Hexicon is able to relieve signs of inflammation, reduce swelling and significantly reduce the severity of signs of the disease.

In childhood

For the treatment of the above infectious diseases in childhood, it is recommended to use Hexicon D. These suppositories are approved for the treatment of gynecological pathologies in children, including:

  • genital herpes;
  • trichomoniasis;
  • vaginitis;
  • syphilis.

Hexicon for men

Some inflammatory diseases in men, they are also treated with Hexicon. Application scheme different forms drug release:

  1. Gel. In the treatment of urological diseases, it is applied to the lesions twice a day for 7-10 days.
  2. Solution. In order to prevent sexually transmitted infections, the liquid is injected into the urethra in an amount of 2-3 ml. The nozzle should be held for 2-3 minutes. In case of inflammation of the urethra, including complicated by prostatitis, for 10 days, 1-2 times a day, the solution is injected into the urethra. The procedure is carried out with a break of 1 day.

drug interaction

If you simultaneously use ethanol, then the effectiveness of the drug will increase. It is not recommended to be treated with Hexicon in conjunction with agents containing iodine. Other features of the interaction of this medication with other drugs:

  • since suppositories are administered intravaginally, their tolerability and effectiveness are not affected by the sanitation of the external genital organs;
  • incompatible with anionic detergents and soaps, in the presence of which chlorhexidine is inactivated;
  • approved for use with drugs containing a cationic group.

Side effects

The most common reactions to the use of suppositories is a local allergic reaction in the form of burning and itching in the vagina. When these symptoms appear, there is no need for specific treatment. They pass on their own after the end of the course of therapy. Very rarely occur adverse reactions and after using the solution. It could be allergies and itching. Judging by the reviews of patients, other undesirable reactions may occur:

  • dermatitis;
  • dry skin of the hands;
  • stickiness of hands;
  • photosensitivity;
  • deposition of tartar;
  • staining of tooth enamel;
  • taste disorder.

Overdose

Due to the fact that the drug is not absorbed from the gastrointestinal tract and is not absorbed through the skin when applied topically, the risk of overdose is minimized. To date, there is no data on the condition that occurs when the dose of the drug is exceeded. Perhaps only amplification side effects whose symptoms resolve on their own.

Contraindications

The main contraindication to the use of all forms of release of Hexicon is hypersensitivity and individual intolerance to the components in the composition. The solution can not be used in case of dermatitis. For the treatment of children, Hexicon D suppositories are optimal. Gel and suppositories are used with great care only as directed by a doctor.

Terms of sale and storage

Any form of release of the drug can be ordered or bought without a prescription from a doctor. The storage place should be dry, and the temperature in it should not exceed 25 degrees for the solution, tablets and suppositories and 20 degrees for the gel.

Hexicon analogue

Complete analogues of the drug are Chlorhexidine solution and Amident. If we compare the mechanisms of action, then Depantol, Bepanten, Tsiteal, Lavasept are closer. The list of analogues can include the following drugs:

  • Iodoxide;
  • Trichomonacid;
  • Dafnedgin;
  • Lactoginal;
  • McMiror;
  • Betadine;
  • Vagiflor;
  • Yodovidone;
  • Hyposol;
  • Furazolidone.

Hexicon price

If you study the catalogs of medicines in several online pharmacies, you can see different prices for Hexicon. This is due to the large number of manufacturers and formulations of the drug. Approximate prices are described in the table:

Where to buy

Release form of Hexicon

Volume, quantity

Price, rubles

Suppositories 16 mg

Candles 16 mg

Zdrav Zone

Candles vaginal 16 mg

Tablets vaginal 16 mg

Children's candles 8 mg

Pharmacy IFK

Suppositories 8 mg

Candles 16 mg

Hexicon D is an antiseptic agent for topical use in gynecology.

Release form and composition

Dosage form - vaginal suppositories: torpedo-shaped, white or white with a yellowish tint, marble surface coloring is possible (5 pcs in blister packs, in a carton pack 1 or 2 packs and instructions for using Hexicon D).

Composition of 1 suppository:

  • active substance: chlorhexidine bigluconate (as a solution with a concentration of 20%) - 8 mg;
  • additional components (the basis of suppositories): macrogol 400 (polyethylene oxide 400), macrogol 1500 (polyethylene oxide 1500).

Pharmacological properties

Pharmacodynamics

The active substance of the drug - chlorhexidine, is an antiseptic that is active against the following microorganisms:

  • gram-negative and gram-positive bacteria: Gardnerella vaginalis, Chlamydia spp., Bacteroides fragilis, Ureaplasma spp., Treponema pallidum, Neisseria gonorrhoeae;
  • viruses: Herpes simplex types 1 and 2;
  • protozoa: Trichomonas vaginalis.

Some strains of Proteus spp. are slightly sensitive to chlorhexidine. and Pseudomonas spp. The drug is not effective in diseases caused by acid-fast bacteria and bacterial spores.

The drug does not violate the functional activity of lactobacilli. Remains active (albeit somewhat reduced) in the presence of pus and blood.

Pharmacokinetics

With intravaginal use, systemic absorption of chlorhexidine is negligible.

Indications for use

Hexicon D suppositories are used for local treatment of genital infections in pediatric gynecology in girls from 6 months of age until menarche:

  • treatment of bacterial vaginosis, vulvovaginitis (including trichomonas, gonorrhea, nonspecific and mixed);
  • prevention of infectious and inflammatory complications in pediatric gynecology (before surgical treatment gynecological diseases);
  • prevention of sexually transmitted diseases (including genital herpes, chlamydia, trichomoniasis, gonorrhea, ureaplasmosis, syphilis).

Contraindications

The use of Hexicon D suppositories is contraindicated in the presence of hypersensitivity to any of the components in the composition of the drug.

Suppositories are not used to treat girls under the age of 6 months.

Hexicon D, instructions for use: method and dosage

The suppository is inserted into the vagina in the supine position, having previously released it from the blister pack.

For medicinal purposes, 1 suppository is prescribed 2 times a day for a course of 7-10 days, in some cases the doctor may extend the treatment up to 20 days.

For the prevention of sexually transmitted diseases, a single use of 1 suppository is recommended no later than 2 hours after sexual intercourse.

Side effects

Hexicon D is mostly well tolerated. In very rare cases (< 0,1%) возникают зуд и аллергические реакции, которые проходят после отмены препарата.

Overdose

No cases of overdose have been reported to date.

special instructions

Candles Hexicon D have a reduced size compared to Hexicon suppositories (especially for the treatment of girls).

Use during pregnancy and lactation

The drug is not contraindicated for use during pregnancy and lactation.

Application in childhood

Suppositories are allowed to be prescribed to girls from 6 months of age.

drug interaction

Hexicon D is incompatible with detergents containing an anionic group (sodium lauryl sulfate, sodium carboxymethylcellulose, saponins) and soaps used intravaginally. The toilet of the external genitalia with soap does not affect the effectiveness of the suppositories, however, the remnants detergent before the introduction of the drug must be thoroughly washed off.

Analogues

Analogues of Hexicon D are: Betadine, Hexicon, Yodovidon, Iodosept, Fluomizin, Chlorhexidine.

Terms and conditions of storage

Store at a temperature not exceeding 25 ° C, out of the reach of children, protected from light and moisture.

Shelf life - 2 years.

Hexicon vaginal suppositories are modern medicine, which is considered the most reliable tool in gynecology, helping in the fight against sexual infections. The medication belongs to antibacterial and antiseptic agents, it easily copes with sexually transmitted diseases. It has a convenient form of release in the form of suppositories, during treatment it is easy to use, when used it does not violate the vaginal microflora.

Indications for use

  • Venereal infectious diseases(syphilis, gonorrhea, chlamydia, trichomoniasis, etc.)
  • Various types of vaginitis.
  • Bacterial colpitis, cervicitis

In addition, the drug is used during gynecological interventions, as well as after childbirth and abortion. Hexicon candles can be used as prophylactic to prevent inflammatory infections. You should also be aware that these suppositories can be used as a contraceptive if other contraceptives are contraindicated.

The composition of the drug

The drug as an active ingredient includes chlorhexidine bigluconate. Additional components are: polyethylene oxide and purified water.

Medicinal properties

Hexicon vaginal suppositories have antiseptic and antimicrobial effects. Due to the content of bigluconate chlorhexidine, the drug is active against gram-positive and gram-negative bacteria. The activity of the drug is not manifested during menstruation, as well as in the presence of pus. Acid-resistant microorganisms are resistant to the effects of the drug.

Release form

Price from 50 to 300 rubles

Hexicon vaginal suppositories are represented by oval-shaped suppositories, white, sometimes yellowish in color. One carton pack contains 10 candles in a blister pack, along with instructions for use. There are also packages with one candle and five.

Mode of application

Hexicon suppositories according to the instructions are used for insertion into the vagina, do not use it anally. In the treatment of infectious and inflammatory diseases, 1 suppository is prescribed 1-2 times a day. It is best to put suppositories at night. The course of treatment is 7-10 days.

For preventive purposes, in order to avoid infection with sexually transmitted diseases, it is recommended to put a candle within 2 hours after unprotected sexual contact.

During menstruation, the effect of the drug is significantly reduced, since the discharge prevents the drug from completely dissolving. However, if treatment is started, it is not advisable to interrupt the course. Most best option start therapy after the end of menstruation.

During pregnancy and breastfeeding

During childbearing and lactation, the drug can be used, since it does not enter the bloodstream and does not adversely affect the fetus, and also does not enter the mother's milk.

Contraindications and precautions

It is forbidden to take medicine in case of:

  • Hypersensitivity to the components of the drug
  • Various kinds of dermatitis
  • Allergies.

Cross-drug interactions

It is not allowed to take the medication in parallel with iodine.

During the reception of detergents of the anionic group, Hexicon suppositories are forbidden to be used.

The medicine is not compatible with soap, from which after hygiene procedures it is necessary to carefully remove all the remnants of soap products.

Ethanol enhances the effect of suppositories.

Side effects

After treatment with Hexicon suppositories, the following side reactions can occasionally be observed:

  • Itching in the vagina
  • Dryness
  • Redness of the mucosa.

Overdose

During the excess of the dosage, an increase in adverse reactions is possible.

Terms and conditions of storage

According to the manufacturer's instructions, candles should be stored in a dry place at room temperature. Shelf life is not more than 3 years.

Analogues

Chlorhexidine

Rosbio LLC, Russia
Price from 250 to 550 rubles

Chlorhexidine is a topical drug that has antiseptic activity against many protozoa. Helps in the treatment of vaginosis, genital infections, accompanied by inflammation. Used before and after surgery in gynecological practice. Produces in the form of a suppository, spray, gel, solution for external use.

Pros:

  • powerful impact
  • Possibility of use during pregnancy.

Minuses:

  • During treatment, it is not advisable to have sex
  • It is not recommended to use during menstruation.

Depantol

Nizhpharm, Russia
Price from 260 to 600 rubles

Depantol is classified as an antimicrobial drug used in gynecology for vaginal administration. Prescribed for chronic and acute form vaginitis, treatment of cervical erosion, various gynecological procedures, etc. The drug is offered in the form of suppositories and creams. The dosage and duration of the course is prescribed by a specialist.

Pros:

  • Quick effect
  • Restores the vaginal mucosa.

Minuses:

  • flow strongly
  • In rare cases, burning is possible.