3 cold tablets azithromycin. Antibiotics for colds, flu and coughs in adults and children

Azithromycin

Sensitive microflora

Pneumococcus.

Moraxella.
Haemophilus stick.
Bordetella.
Neisseria.
Gardnerella.
Legionella.
Clostridia.
Mycobacteria.
Mycoplasma and ureaplasma.
Chlamydia.
Pale spirochete.

Indications

Pharyngitis and tonsillitis.
Otitis.
sinusitis.
Erysipelas and impetigo.
Pyodermatosis.

Reception features

Release form

Feeling better.

Trade names

Complications of treatment

Antibiotic preparations for a three-day course of administration

tonsillitis;
pneumonia;
bronchitis;
urethritis;
cervicitis;
skin diseases;

abscesses of the pharynx;
meningitis;
mediastinitis;
sepsis;
glomerulonephritis.

Due to the powerful effect of the substance, the course of treatment with this drug is limited to three tablets. Full recovery occurs a few days after the end of the course of treatment.

the first day - one tablet;

Indicated for use with:

Skin infections.
STD.

headache;
state of drowsiness;
feeling dizzy;
increased heart rate;

Antibiotics for colds, flu and coughs in adults and children. What antibiotics to take

Antibiotics are substances of natural or synthetic origin that release toxins that are harmful to bacteria and microorganisms. According to their purpose, antibiotics are divided into antibacterial, antifungal and antitumor drugs.

The indiscriminate use of drugs leads to the adaptation of pathogens and bacteria. They mutate and become resistant to antibiotic toxins. Medicines stop working.

How to take antibiotics for a cold

Antibiotics are prescribed only for bacterial or fungal infections. At viral diseases resort to antiviral drugs. The use of antibiotics at the first signs of acute respiratory infections is unreasonable and harmful.

Taking antibiotics for colds in adults and children can significantly reduce the duration of the disease and make life easier.

On the 4-5th day, the effect of the virus disappears, the patient feels better, but his immunity is reduced, and the likelihood of complications remains. An increase in body temperature increases The lymph nodes, found redness in the throat, wheezing in the bronchi.

This means that a bacterial or fungal infection begins to develop in the body. In this case, antibiotics are prescribed.

How many days to take antibiotics for a cold

Adults are prescribed an antibiotic in the form of tablets, capsules or powder. Children due to their age cannot swallow the pill. They are prescribed drugs in the form of syrup.

The duration of therapy is determined by the doctor. In general, it lasts 5-7 days. The doctor describes the regimen for taking the antibiotic: it is indicated in the description of the drug. The scheme depends on the age of the patient and the drug group.

The rules described by the therapist and indicated in the instructions for use of the drug cannot be changed. The effectiveness of therapy depends on this. If the doctor indicated that it is necessary to take the drug 2 times a day, then the time of admission must be calculated. 24 hours / 2 times = 12 hours.

This means that it is necessary to drink the medicine after 12 hours. If the first dose of the medicine was taken at 8 am, then the next dose will be at 8 pm.

Note! The course of therapy with antibiotics should not be interrupted, even if the patient's health improves. A decrease in temperature, the absence of cough and runny nose does not mean that pathogenic bacteria have stopped their reproduction.

The pain subsided but did not go away. It will begin to develop again, but the effect of the drug that was taken earlier will be ineffective. The therapist prescribes another antibiotic, which has a stronger effect.

Antibiotics for colds in adults

An adult person has already formed immunity, which is able to quickly recover. The therapist evaluates the effectiveness of the drug in a complication of a certain type: a disease of the upper respiratory tract, respiratory tract, the development of mycoplasmosis.

Penicillin series: "Penicillin", "Benzylpenicillin". The drugs are administered by injection. Gastric juice reduces the effect of penicillin tablets.
Cephalosporins: "Ceftolozan", "Cefalexin", - capsules or suspensions. The drugs are effective in diseases of the respiratory tract.
Macrolides: "Erythromycin", - is prescribed for intracellular infections, mycoplasmosis.

Tetracyclines: tablets "Tetracycline", capsules "Doxycycline", "Menocycline". Drugs are prescribed for adults and children from 8 years of age.
Fluoroquinolones: Levofloxacin, Ciprofloxacin, are effective in the development of inflammation of the ENT organs. Drugs are prescribed to patients from 18 years of age.
Lincosamides: "Lincomycin" in tablets, capsules, injection solutions. Preparations of this group are prescribed for angina, bronchitis, sinusitis.
Carbapenems: "Ertapenem", "Meropenem", - are indicated for pneumonia.

Broad spectrum antibiotics for colds

To determine the effectiveness of the drug for the body, the doctor needs to determine the patient's sensitivity to a particular type of antibiotic. For the test, you need to take a blood test.

The result is prepared in 5-7 days. The infection will progress at this time, so the therapist prescribes broad-spectrum antibiotics:

The doctor prescribes taking antibiotics with a wide spectrum of action, based on the symptoms of the disease, on the epidemiological situation in the region.

If the drug does not have the desired effect, the infection continues to progress, then the therapy is adjusted according to the results of the antibiotic sensitivity test.

Three pills: a strong antibiotic for colds

The effectiveness and strength of the drug is determined by some parameters: how quickly it is absorbed and distributed throughout the body.

In some cases, it is enough to take 3 tablets to achieve success in treating a cold. Strong drugs include:

One of the forms of release of these drugs is tablets: take 1, 3 days. Medicines are available not only in tablets, but also in the form of suspensions, capsules. Only a doctor can determine the appropriateness of therapy.

Mild antibiotics for colds

The most toxic drugs are antibiotics of the aminoglycoside group: they lead to complications. Macrolides are less dangerous: they are prescribed to pregnant women and children. Antibiotics that do not cause complications are defined as mild. These include:

The drugs have a gentle effect on the flora of the intestines and stomach. They do not kill enterobacteria. Eating does not affect the effectiveness of the antibiotic: drugs are taken both before and after meals.

The active substance of the drugs is rapidly absorbed from the stomach and distributed throughout the body.

Antibiotics for flu and colds for adults over 50

Elderly patients are prescribed antibiotics with great caution. Metabolic processes in the body are reduced, which slows down the excretion of drugs from the body, their absorption and distribution through soft tissues.

Elderly patients often suffer from chronic diseases of the heart, kidneys, gastrointestinal tract. Antibiotics for people over 50 are prescribed in small doses.

In the instructions for the use of drugs are given special instructions: how to take medicine with chronic diseases. If the symptoms of a cold are observed within 2 days, then the therapist prescribes antibiotic therapy of the 3rd and 4th generation fluoroquinolones.

In exceptional cases, cephalosporins are prescribed. Elderly people are instructed to:

These drugs are distributed in soft tissues in 20 minutes. Excreted with feces and urine. Antibiotics are taken after surgery to avoid the development of a secondary infection in the body.

Antibiotics for colds: "Amoxicillin", its action, contraindications

"Amoxicillin" is an antibiotic of the penicillin group, has a wide spectrum of action. The drug is produced in the form of tablets, granules for suspension, capsules.

The solution in ampoules is used in veterinary medicine. The active substance, amoxicillin, is absorbed by the body from the gastrointestinal tract without disturbing the acidic environment.

Eating does not affect the distribution of the active substance throughout the body. Suitable for the elderly.

The drug is prescribed to the patient, in case of infection:

upper respiratory tract;
digestive organs;
genitourinary system;
with soft tissue injury.

"Amoxicillin" is used in conjunction with "Metronidazole" in the treatment of ulcers duodenum and gastritis.

The drug has contraindications:

allergic diathesis;
sensitivity of the patient to antibiotics of the penicillin, cephalosporin group, to nitroimidazole;
diseases of the gastrointestinal tract, which are accompanied by diarrhea and severe vomiting;
viral respiratory diseases;
asthma;
lymphocytic leukemia;
mononucleosis, in which there is an increase in the spleen, liver;
diseases associated with impaired hematopoiesis;
disorders of the nervous system;
liver dysfunction, jaundice.

"Amoxicillin" in the form of a suspension is prescribed for children from 2 years of age. Tablets are prescribed for adults and children over 12 years of age. The doctor prescribes the antibiotic regimen. It depends on the form of the drug, the age of the patient and the specifics of the disease.

Analogues of "Amoxicillin" are: "Ampicillin trihydrate", "Ecobol", "Ospamox". The average price of the drug is 70 rubles.

Antibiotics for colds for children up to a year

The appointment of antibiotics for infants up to a year should be justified. Antibiotic therapy may lead to underdevelopment internal organs and the brain. From 3 months, children are prescribed:

Infants are not prescribed antibiotics:

with acute respiratory infections caused by a virus;
with rhinitis;
with pharyngitis;
before treating a cough, the pediatrician studies its origin; if a prolonged cough is of a bacterial nature, then the appointment of antibiotics will be justified;
with hyperthermia, high body temperature, which lasts more than a day, if the child cannot be examined, Cephalosporin is prescribed.

It's important to know! To normalize the intestinal microflora, the pediatrician recommends taking bifido- and lactobacilli. You should not neglect the advice of a doctor. Otherwise, the baby will suffer from colic, flatulence, diarrhea or constipation.

Antibiotics for colds for children after a year

The body of an infant and a child after a year is distinguished by a stronger immune system and the harmonious functioning of internal organs. Children after a year with a cold are prescribed antibiotics in the form of injections and orally: tablets, suspensions, syrups.

"Aksetin" - powder for the preparation of an injection solution, shown to children from birth;
"Klacid" - shown to children from 3 years of age;
"Amoxisar" - prescribed to children under 5 years of age in the form of a suspension;
"Cedex" - suspensions for children from 6 months, tablets - from 10 years;
"Flemoxin Solutab" - for young children, the antibiotic is given in the form of a syrup; older children are prescribed pills.

Urticaria may appear after taking antibiotics. In this case, the drug is either canceled or antihistamines Suprastin, Zodak, Tavegil are prescribed.

Antibiotics for colds in children: the names of the most effective

The pediatrician prescribes antibiotic therapy individually for each child. For some children, drugs of the penicillin group are effective, for others - macrolides.

Experts identify the following bactericidal and antimicrobial agents that are effective for children with a cold:

"Zinnat" - the active substance - cefuroxime axetil; the granules are diluted with water to obtain a suspension; the medicine has a fruity taste, is indicated for children from birth;

"Augmentin" - the active substance - amoxicillin trihydrate; powder for suspension preparation; has a berry sweet taste, prescribed for children from 2 months;
"Supraks" - the active substance cefixime; tablets, soluble in water; taste - sweet, strawberry, prescribed for children from 3 years old;
"Roxithromycin" - tablets, recommended for children from 12 years old.

Important to remember! Antibiotics taken for colds in adults and children should be taken with plenty of clean water. Sweet carbonated drinks, compote or tea should not be used. Do not drink drugs with milk and sour-milk drinks.

Improper medication reduces the dissolution of the antibiotic, its absorption and distribution throughout the body.

What antibiotics to take for colds and sore throats

If you have a sore throat with a cold, then antibiotics are not prescribed immediately. The therapist determines the nature of the disease, viral or bactericidal. With angina caused by staphylococcus, the patient has certain signs:

heat up to 40 °C; use antipyretics that reduce the temperature for a short time;
it is painful for the patient to swallow;
burgundy tonsils, visible on them white coating and manifestations of abscesses;
enlarged lymph nodes: on palpation, the patient feels pain.

At staph infection in the throat, the therapist may prescribe sprays or aerosols:

Attention! Sprays for angina are not prescribed as an independent antibacterial agent. Prescribe complex treatment together with antibiotics in tablets, suspensions or in the form of syrup.

Treatment will be effective if, before using the spray, rinse the throat with a decoction of chamomile or sage.

Antibiotics for SARS and influenza

Diseases caused by a virus entering the body are treated with antiviral medicines.

If the patient's condition does not improve: the temperature is above 38.5 ° C, abundant separation of the mucous membrane from the nose is green, there are signs of otitis media, then the doctor corrects the treatment. He prescribes antibiotics. In this case, broad-spectrum drugs will be effective:

Clonacom-X: combined antibiotic; its active substances are amoxicillin and cloxacillin; with caution appoint women during pregnancy and children under 14 years of age, the course of treatment is 10 days;
"Ampisid": for adults and children whose body weight has reached 30 kg; a contraindication is sensitivity to the drug; during pregnancy, the drug is prescribed with caution; effective in the treatment of ENT organs, upper respiratory tract, diseases of the gastrointestinal tract, genitourinary system;

"Fromilid": granules for suspension, tablets; the active substance is clarithromycin; contraindication is kidney disease; children are prescribed the drug from the age of 12.

The therapist should determine the dosage and method of taking antibiotics. Drugs are dispensed in pharmacies by prescription.

Antibiotics for colds and coughs

Before prescribing an antibiotic for coughing, the therapist will prescribe tests and examinations for the patient. If the cough is caused by the spread of a bacterial infection, then they resort to therapy with antibacterial agents. Antibiotics for colds in adults and children are indicated for pleurisy, pneumonia, acute tracheitis, bacterial bronchitis.

"Zi-factor": the drug is prescribed for adults and children from 1 year; contraindications - renal and hepatic insufficiency;
"Azitsid": course of treatment 3 days - 3 tablets; for adults, children from 3 years old, for pregnant women;
"Ecoclave": produced in the form of tablets and powder for suspension.

In the treatment of cough is always carried out complex therapy. Together with antibiotics, antitussives or expectorants are prescribed.

Natural antibiotics for colds

Synthetic antibiotics destroy not only pathogenic bacteria in the body, but also beneficial intestinal microflora. Medicines reduce the patient's immunity.

After treatment, a new therapy is needed to restore the functions of the gastrointestinal tract and immune system. Natural antibiotics act on the body in a gentle way. Experts recommend including them in your daily diet.

Berries are known for their antiseptic, antiviral and bactericidal properties:

viburnum - tastes like raspberries, but is not popular because of the specific smell;
cranberry;
black currant;
raspberry;
sea buckthorn;
blueberry.

The berries are ground with sugar and kept in a glass container in a cool place. Use 1 tsp. 3 times a day for the prevention and treatment of colds.

Some seasonings increase immunity, normalize metabolic processes and are natural antibiotics:

Seasonings are used in salads and second courses. In the treatment of angina, decoctions are made from them for rinsing the throat, washing the nose.

One of the most delicious natural antibiotics is honey. A spoonful of honey is added to tea, milk or absorbed with a sore throat.

Antiviral antibiotics for colds

Antiviral antibiotics exist only in nature. Kalina, garlic, cranberries have not only antimicrobial and bacteriostatic effects, but also antiviral properties. There are no synthetic antibiotics that prevent the reproduction of viruses.

Antibiotics and antiviral drugs act on different pathogens. With ARVI, "Arbidol", "Remantadin" are prescribed. After 4-5 days, the immune system produces antibodies that resist the virus.

Further complications are associated with the development of infection caused by the activity of bacteria or fungi.

In some cases, a secondary infection develops already during the infection of the body with a virus. Human superinfection occurs. In this case, the doctor prescribes therapy with antiviral drugs and antibiotics.

Antibiotics for colds are inexpensive and effective, their names and features

Penicillins are prescribed for streptococcal, staphylococcal, pneumococcal infection. They do not have high toxicity: they are suitable for children. Among them:

"Benzylpenicillin benzathine" - the cost in tablets from 30 rubles. for 10 pieces; injections - 60 rubles. for 1 ampoule; possible use with antifungal drugs;
"Ampioks" - from 60 rubles. for 20 pcs.; recommended for children from 7 years old;
"Oxacillin" - in tablets from 55 rubles / 20 pcs.; powder No. 50 - 450 rubles.

Cephalosporins have a wide spectrum of activity: they are active against coccal and anaerobic infections. In some cases, appoint combined preparations that contain penicillin.

The least expensive and effective are the following drugs:

"Zinacef" for intramuscular and intravenous use; powder for solution - from 140 rubles. for 750 mg;
"Lopraks" - the average price is 120 rubles; the drug is produced in tablets and in the form of a powder for the preparation of a suspension;
"Cefoperazone" - the average price is 150 rubles; powder for injection.

Modern antibiotics have a wide spectrum of action and low toxicity. Their cost is not democratic. The average price is from 500 rubles.

Over-the-counter antibiotics

The Ministry of Health of the Russian Federation has always opposed self-treatment. The law on the sale of medicines was passed in 2010. In 2017, pharmacy owners were reminded of the responsibility for selling antibiotics without a doctor's prescription.

A legal entity will pay a fine of 40 thousand rubles. IP owner - from 4 thousand rubles. The activities of organizations may be suspended for 90 days by a court decision.

To purchase an antibiotic, you need to visit a doctor who has the right to write prescriptions.

Injections: antibiotics for colds, their names, action, contraindications

Injections for colds are prescribed for difficult cases, when necessary intensive therapy. The injections work faster and more efficiently. Injections are prescribed only for certain indications.

"Sultasin" - from 40 rubles. for a bottle of powder for solution preparation; the drug is combined, has an antimicrobial and bacteriostatic effect, a contraindication is liver and kidney disease;
"Oxamp-sodium" - the average cost is 20 rubles / 1 bottle; belongs to the group of penicillins, not prescribed for children infancy if the mother has a history of sensitivity to penicillin; contraindications - bleeding, bronchial asthma, sensitivity to the drug;
"Amoxicillin + Clavulanic acid": do not prescribe injections for jaundice, infectious mononucleosis, hypersensitivity.

Carefully! If a powder with an antibiotic for the preparation of an injection solution remains from the last treatment, then it is not worth prescribing injections on your own.

There is a danger that the body has developed resistance to this antibiotic. The use of drugs in this case will harm the body.

Antibiotics for pregnant women with a cold

Bactericidal and antimicrobial drugs for pregnant women are prescribed with great care. A woman should be under the constant supervision of a doctor. Antibiotics are prescribed in extreme cases, if after acute respiratory infections pneumonia, purulent bronchitis have developed, the organs of the genitourinary system are affected.

For pregnant women, the following drugs are prescribed:

The dosage of drugs is reduced so as not to harm the fetus. In some cases, the therapist prescribes medications that are suitable for children from infancy.

The following groups of drugs are prohibited for pregnant women:

tetracyclines;
sulfonamides;
chloramphenicol series;
nitrofuran group.

In the 1st trimester, antibiotics are not recommended. 2-3 trimesters are less dangerous. Along with drugs, it is recommended to take vitamin complexes for pregnant women.

Treatment of a cold with antibiotics: the consequences of therapy

Therapy with the use of an antibiotic will not harm the body if the doctor has correctly selected the drug and determined the correct regimen for taking the medicine.

With a reduced immunity of the patient, if the rules for taking antibiotics are not followed, negative manifestations are possible. First of all, they relate to the gastrointestinal tract:

Antibiotics negatively affect not only pathogenic bacteria, but also beneficial microflora. As a result of therapy, an imbalance of bacteria in the intestine occurs, which will require a long recovery.

Antibiotics upset the balance of mucous membranes in the body. This leads to the development of fungi of the genus Candida. The patient suffers from stomatitis and thrush: it is more common in women and girls.

Antibiotic toxins adversely affect liver function. The patient has signs of jaundice.

After a course of antibiotics, you need to take:

The therapist will make recommendations on dietary nutrition and treatment of dysbacteriosis. Treatment of the patient with antibiotics should be under the supervision of a doctor. Otherwise, the restoration of immunity and the functions of internal organs will take a long time.

Antibiotics in the period of acute respiratory infections are prescribed only according to indications and on the basis of tests. It is dangerous to take medicine for a cold on your own.

Antibiotics for colds in adults and children:

Useful video about rehabilitation after antibiotics. School of Dr. Komarovsky:

I try not to drink antibiotics to the last and not give the child. But a couple of times my son had serious infections, the temperature was 39 for several days, I had to. They took sumamed, and naturally the microflora was restored, linex was taken at the same time. Both times, one course was enough, they were cured in a week.

Antibiotic that is drunk for 3 days

Some diseases cannot be cured without antibiotics. And the drug of choice is most often a broad-spectrum drug with a short course of administration. Such therapy is more easily tolerated by patients, and it is less likely that the treatment will end prematurely.

Short course of treatment

More recently, antibacterial drugs had to be taken for 7-10 days, often 3-4 times a day. This caused significant inconvenience to patients, and most sought to stop therapy as soon as possible.

Modern antibiotics compare favorably with their predecessors. Usually they are taken no more than 5-7 days, 1-2 times a day. In addition, most of these medicines come in the form of tablets and capsules rather than injectable solutions.

Among them, the most popular drugs containing azithromycin. The duration of therapy with such a medicine is three, less often five days. If it is necessary to take antibiotics for 3 days, patients are more enthusiastic about treatment - confidence in the doctor increases, the effectiveness of therapy increases.

Azithromycin

Azithromycin belongs to the group of macrolides and belongs to the broad-spectrum antibiotics. A short course of treatment with this drug is associated with the peculiarities of its pharmacokinetics.

Azithromycin remains in the tissues at a high level for 5-7 days after taking the last tablet. This concentration is sufficient for the manifestation of its full antibacterial action. And despite the fact that patients no longer drink the medicine, azithromycin continues to be active in their body.

The drug is well absorbed in the gastrointestinal tract, but if you take the pills after a meal, this process slows down.

The drug is stable in an acidic environment and therefore does not break down in the stomach.

Sensitive microflora

The list of pathogens sensitive to the action of azithromycin is quite extensive. In the group of gram-positive bacteria, the following microorganisms are distinguished:

Staphylococcus aureus and epidermal.
Pneumococcus.
Pyogenic streptococcus, as well as groups G, F, C.

The list of Gram-negative microflora sensitive to azithromycin is even longer. Most often it is used to treat diseases caused by such pathogens:

Moraxella.
Haemophilus stick.
Bordetella.
Neisseria.
Gardnerella.
Legionella.
Clostridia.
Mycobacteria.
Mycoplasma and ureaplasma.
Chlamydia.
Pale spirochete.

Azithromycin is usually bacteriostatic. However, when treated with high doses of this drug, the effect is bactericidal.

A significant number of microorganisms sensitive to it and a three-day course of administration makes azithromycin the drug of choice for many diseases. Indications for its use may be different.

Indications

Azithromycin is effective in pathologies of the skin and soft tissues, ENT organs, respiratory and genitourinary systems.

By taking this antibiotic, in 3 days you can cope with such diseases:

Pharyngitis and tonsillitis.
Otitis.
sinusitis.
Bronchitis and pneumonia. For pneumonia, azithromycin is usually given in combination with a second antibiotic.
Erysipelas and impetigo.
Pyodermatosis.
Lyme disease in the stage of erythema migrans.
Chlamydial urethritis or cervicitis.

Azithromycin is often combined with antibiotics penicillin series such as amoxiclav. In this case, the effectiveness of therapy is significantly increased.

Reception features

How to drink antibiotics that contain azithromycin? Patients should be aware that only a doctor prescribes such a treatment regimen. It takes into account the type of disease, the characteristics of the body, the reactions that were against the background of previous therapy.

If patients have previously taken these tablets, it may make sense to change the antibacterial drug to avoid the development of drug resistance. However, only a specialist does all this.

Self-medication with a bacterial infection can lead to a chronic process, the formation of microorganism resistance, and the development of candidiasis.

Release form

Azithromycin is available in tablets and capsules. Its dosages are different - 125, 250 and 500 mg. Also, this drug is sold in the form of a suspension. This dosage form is widely used in pediatrics, in children under three years of age.

Usually azithromycin is actually taken within three days. This is sufficient to develop a highly effective drug response. Do not forget that a certain concentration active ingredient remains in the blood for about a week.

On the third day, the effectiveness of the treatment is evaluated. The therapeutic course can be completed if the patient:

Significantly reduced or completely normal body temperature.
Feeling better.
Unpleasant symptoms subside or disappear.

If at this time repeat the general clinical analysis blood, it will be possible to see the normalization of the main indicators.

Trade names

It is not uncommon to hear in a pharmacy how customers ask about an antibiotic for 3 days, the name of which they forgot. Most often, such people self-medicate, and this is unacceptable. Antibacterial drugs should always be purchased according to a prescribed medical prescription.

Another thing is if the pharmacy does not have a specific drug. In such a situation, it is quite possible to use another containing the same active substance. This antibiotic is known in pharmacies under the following names:

There are other trade names for this antibacterial drug, because it is produced by many manufacturing companies.

However, it is these drugs that are most famous and popular among both doctors and patients.

Complications of treatment

If patients drink the medicine for 3-5 days, they rarely experience side effects. In most cases, this drug is well tolerated, although the following symptoms may occasionally occur:

Occasionally, this antibiotic affects the blood system with the development of neutropenia, leukopenia and eosinophilia. As with other drugs in this class, it may exacerbate candidiasis by destroying normal microflora.

A contraindication to treatment with azithromycin is its intolerance.

During pregnancy and lactation, it is prescribed with caution, taking into account possible risks and negative consequences.

Combination with other drugs

Azithromycin can be administered simultaneously with antibiotics of other groups. A combination with penicillin drugs has proven itself well in community-acquired pneumonia.

Non-steroidal anti-inflammatory drugs, which are also often prescribed for pathologies of ENT organs and respiratory system.

Antibiotic "for three days" called azithromycin appeared on the pharmaceutical market not so long ago, but very quickly established itself as highly effective and sufficient safe remedy with many diseases.

Off-season - the time of epidemic outbreaks colds and exacerbation of chronic infections. The modern dynamic rhythm of life does not allow you to get sick for a long time, so an antibiotic for three days, effective against inflammation of the upper respiratory tract, has gained popularity.

Patients, according to reviews, notice a noticeable relief of the condition already on the second day of admission, and due to the prolonged action of a three-day course, it is enough to treat diseases of mild and moderate severity.

However, at the first sign of a cold, you should not rush to the pharmacy for a miracle remedy. First you need to figure out what kind of drug it is, how it works and what its purpose is. In addition, a visit to the therapist is required, who will prescribe the appropriate medicine.

Azithromycin

This is the name of the drug, which allows you to quickly get rid of respiratory diseases.

It is an antibiotic, three tablets of which make up the full course of treatment.

Belongs to the class of macrolides, active against a greater number of pathogens than penicillins or fluoroquinolones. The first generations of these antibacterial agents were designed for long-term use, and at least 2 doses should be taken per day. The formula of Azithromycin, allocated to a separate subclass of azalides, due to some structural differences, provides a prolonged action. Due to this, only three times the application is enough, since the therapeutic concentration of the antibiotic in the blood lasts up to 5-7 days.

Operating principle

The drug has a bacteriostatic effect, that is, it stops the development of pathogens. This happens due to the introduction of the active substance into the cell, attaching to its ribosomes and blocking the synthesis of the protein necessary for growth. With an increase in concentration, the drug acquires bactericidal properties, killing the pathogen. Therapeutic effect develops within the first 2 hours after ingestion and lasts about a day.

An antibiotic course of 3 tablets is active against the following intra- and extracellular pathogenic bacteria:

gram-positive streptococci that cause pneumonia, scarlet fever, endocarditis, rheumatism, postpartum blood poisoning, nephritis, inflammation of the larynx, epidermis and soft tissues;
pneumococci, which inflame the lungs, middle ear, paranasal sinuses and meninges;
Staphylococcus aureus - the causes of a wide variety of diseases (from aesthetically unpleasant acne to deadly sepsis and meningitis) and persistent nosocomial infections;
gram-negative legionella, gardnerella, gonococci, haemophilus influenzae and whooping cough, chlamydia, mycoplasmas and pale treponema.

Microorganisms resistant to erythromycin are also resistant to azithromycin.

At the moment, macrolides in general and azalides in particular occupy one of the leading places in the treatment of infectious diseases in adults and children. This is explained by their high efficiency and at the same time very low toxicity. In addition, most strains of pathogenic bacteria have acquired resistance to penicillins, which were widely used in the past.

A bit of history

The "fastest" three-day antibiotic - three tablets for three days - was first synthesized in the 80s of the last century by employees of the pharmaceutical laboratory of the Croatian company Pliva. It was obtained by modifying the 14-membered structure of erythromycin and became a representative of the third generation of macrolides. At the same time, the features of the chemical structure made it possible to attribute it to a separate subgroup - azalides.

The prerequisite for the emergence of such a powerful and effective remedy was the invention by American researchers back in 1952 of erythromycin. The drug, which became the founder of the macrolide group, was obtained from an actinomycete living in the soil. A drug similar in spectrum of antimicrobial action to penicillins has become their alternative for patients with allergies.

The promise of a new class of ABP inspired scientists to further develop and create more effective medicines. The latest achievement in this direction was Azithromycin, which surpasses erythromycin in acid resistance by almost 300 times.

The American pharmaceutical company Pfizer introduced it in the US and Western Europe under the trade name Zithromax. In Eastern Europe, the drug is known as Sumamed. Currently, there are more than 20 medicines based on Azithromycin.

Antibiotic three tablets per pack: name, analogues, application

The active ingredient of all medications belonging to the azalide subclass is azithromycin. This name is also registered as a trademark, but different manufacturers produce analogues under other names. The complete list includes the following medicines:

As a confirmation of the reliability of the list, we attach a photo gallery with these medicines.

All medicines included in the list have a similar effect and general rules reception.

Indications

The drug is produced in different dosage forms: there are granules from which a suspension is prepared, special powders for injection solutions, a lyophilisate. However, the most popular type of antibiotic is three capsules or tablets that make up the full course of treatment. respiratory infections respiratory organs.

To cure light form sinusitis, pharyngitis and laryngitis should be taken 1 tablet 0.5 g every 24 hours for three days (1 hour before or 2 after a meal). With otitis media, moderate sinusitis, tonsillitis and scarlet fever, a five-day course is indicated. The duration of therapy for NDP infections depends on the severity of the disease and the sensitivity of the pathogen.

Inflammation of the epidermis and soft tissues, organs of the genitourinary system and small pelvis, as well as stomach ulcers are treated according to a different scheme. For example, with urethritis, a single dose of 1 gram of the drug is sufficient, with borreliosis, a five-day course is required, and as part of the complex eradication of Helicobacter Azithromycin, three days are taken, but 1 gram each. With antibiotic therapy of pneumonia, intravenous administration is first recommended, with a further transition to tablets. The duration of treatment depends on the sensitivity of the pathogen, the severity of the condition and the rate of resorption of the inflammatory focus.

The dosages given indicate how adults should take azithromycin. For children, the required amount of medicine is calculated based on their weight. So, for every kilogram of body weight of a child, there should be a mg of active substance, depending on the duration of the course (3 or 5 days). Most often, in this case, powders or granules are prescribed, from which a suspension is prepared. In addition, there are a number of age restrictions for certain dosage forms.

Contraindications

Azithromycin should not be taken by persons with hypersensitivity to macrolides, as well as liver and kidney failure, arrhythmia. Strict contraindications include the age of children under 6 months. After six months, and up to 12 years, the drug is used only in the form of a suspension, since the effect of other dosage forms on children has not been reliably studied.

With caution, 3 tablets of an antibiotic called Azithromycin or another brand name are prescribed during pregnancy. Despite the low toxicity, there is no complete information about the safety of macrolides for a developing fetus. In this regard, the drug can be used by pregnant women only in the case when the undoubted health benefits of the expectant mother are higher. potential harm for a child. With antibiotic therapy during lactation, treatment is carried out strictly under the supervision of the attending physician, if necessary (long course), it is recommended to stop breastfeeding for a while, expressing milk.

Side effect

The low toxicity of Azithromycin and analogues determines the incidence of side effects.

Dysbacteriosis and allergy characteristic of taking antibiotics are observed in less than 5% of cases.

Even less often there are violations of the activity of the heart, nervous and genitourinary systems. For example, dizziness, tachycardia and candidiasis develop in only 1% of patients.

Antibiotic therapy for influenza and respiratory diseases

Will the magic three cold pills help or is the antibiotic not effective in this case? Of course, it is very convenient to recover from a cough and runny nose in just a couple of days, and not drink medicine for a week without noticing significant improvements. But before taking Azithromycin or its analogues, you must definitely go to the doctor. Self-medication is unacceptable for several reasons:

All antibacterial drugs are designed to fight infections caused solely by bacteria, as the name suggests. That is, with a cold or flu caused by a virus, ABPs simply will not help. Moreover, side effects worsen the general condition and often provoke complications.
Despite a very wide range of antimicrobial action, an antibiotic for 3 days called Azithromycin or its analogues is not at all a panacea for infectious diseases. It is likely that the inflammation was caused by a strain resistant to this agent. In this case, as in the previous one, treatment will only bring harm.
Only a doctor can reliably determine the pathogen and prescribe adequate therapy. This is done on the basis of the results of a laboratory study that provides information about the specific bacterium that caused the disease.
Again, only a specialist is able to choose the optimal antibiotic therapy regimen, taking into account contraindications, the age of the patient and his individual features.

Influenza and colds are treated with antiviral medicines, bed rest and symptomatic remedies (antipyretic tablets, cough syrups and drops for the common cold).

It is advisable to use antibiotics for ARVI in the presence of bacterial complications. However, here, too, an appeal to a medical facility is mandatory, since only a doctor can choose the right antibacterial drug, its dosage and duration of treatment.

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Antibiotic drugs are used to treat bacterial infections. Antibiotics are effective therapy the most common forms of diseases such as:

fibrous, follicular, phlegmonous, lacunar tonsillitis;
tonsillitis;
pneumonia;
bronchitis;
urethritis;
cervicitis;
skin diseases;
diseases of the gastrointestinal tract.

All of the listed ailments must be treated immediately and only with antibiotics in order to avoid serious complications and further dissemination infections.

Lack of adequate and timely antibiotic therapy can lead to:

abscesses of the pharynx;
meningitis;
mediastinitis;
sepsis;
acute rheumatic fever;
infectious-toxic shock;
glomerulonephritis.

Some of these conditions are treated only by surgical intervention and subsequent long drug therapy. All these complications often cause the development of chronic pathological processes, or conditions that can threaten the life of the patient.

Important! The selection of an antibiotic drug, the appointment of a dosage and a course of therapy is carried out exclusively by a doctor! Independent and uncontrolled antibiotic treatment is not allowed!

Benefits of a three-day course of antibiotic therapy

Azithromycin is a broad-spectrum antibiotic drug that quickly and without complications provides a complete recovery from a bacterial infection. Accumulating in tissues, it affects pathogenic microorganisms and destroys them.

The principle of action of this drug lies in its ability to block the function of protein synthesis by pathogenic microorganisms, leading to their destruction.

Azithromycin has good resistance to gastric juice and completely absorbed into the gastrointestinal tract. A long period of elimination of azithromycin from the body ensures the preservation of therapeutic properties for a week after the end of the course. A low percentage of possible side effects allows the appointment of medication even for children.

The liver is the main organ of the human body, which takes an active part in the transformation of drugs taken by a person. That is why it is so important to protect your liver from negative effects after or during the forced use of antibiotics with the help of ...

As noted above, the antibiotic azithromycin provides complete recovery after taking only three tablets, one package containing three 500 mg tablets is designed for three days of intake by an adult. In some cases, taking three tablets is more appropriate to divide into five days. In this case, the drug is taken according to the scheme:

the first day - one tablet;
the second and subsequent days, half a tablet.

For the treatment of children, the dosage of the drug is calculated taking into account the weight of the baby, at the rate of 10 mg per kilogram of weight on the first day of treatment, and in the next four days the dose of the drug is reduced by 5 mg.

The use of the antibiotic azithromycin requires heightened attention and caution in such cases:

with individual sensitivity of the patient to drugs of the macrolide group
with severe hepatic and renal pathologies
with allergic reactions to the components of the drug
in children up to six months of age.

At the age of six months to twelve years (with a child weighing less than 45 kg), it is not recommended to take the drug in the form of tablets and capsules; at the age of sixteen years, intravenous administration of the drug is not recommended.

During pregnancy and during the period of breastfeeding, the medication is allowed to be taken if the effect of the drug on the health of the mother exceeds the threat to the health and life of the fetus.

Antibiotic drugs based on azithromycin

Sumamed is an antibiotic based on azithromycin, which is also available in three tablets per pack.

Indicated for use with:

Feedback from our reader - Maria Ostapova

I recently read an article that said that you need to start treating any disease with cleansing the liver. And it was told about the Leviron Duo remedy for protecting and cleansing the liver. With the help of this drug, you can not only protect your liver from the negative effects of taking antibiotics, but also restore it.

I was not used to trusting any information, but I decided to check and ordered a package. I started taking it and noticed that I had strength, I became more energetic, the bitterness in my mouth disappeared, the discomfort in my stomach disappeared, my complexion improved. Try it and you, and if anyone is interested, then below is a link to the article.

Infectious diseases of the upper and lower respiratory tract.
Skin infections.
STD.

Admission course this tool also calculated for three or five days depending on the disease. At infectious diseases of the respiratory system, a course is prescribed for three days, one tablet per day, and in the chronic stage of erythema, the course of therapy is five days, according to the scheme: the first day, two tablets, the next - one.

The use of Sumamed for therapy acute stages urogenital infections is limited to a single dose of a double dose (two tablets of 500 mg once).

Important! If the patient misses a dose of the drug, then it is necessary to take the missed dose of antibiotic as soon as possible, and take subsequent tablets no earlier than 24 hours later.

Contraindications for taking this medicinal product the same as for Azithromycin.

Also, based on azithromycin, drugs are produced with the following names:

All of these drugs have various forms release, with a different dosage of the active ingredient. These can be tablets, 125 mg, six pieces per pack, or 500 mg, 3 pieces per pack. Also available in capsule, powder or syrup form. The recommended daily dose for an adult is 500 mg.

Side effects and risk of overdose

The drug is taken orally one hour before a meal or two hours after a meal.

Rare side effects of drugs include:

headache;
state of drowsiness;
feeling dizzy;
increased heart rate;
the appearance of nausea, diarrhea, vomiting;
development of vaginal candidiasis;
the occurrence of urticaria, conjunctivitis, itching.

Simultaneous intake of these antibiotics with food or ethanol can lead to a slowdown and decrease in absorption. With simultaneous therapy with azithromycin and drugs that reduce the acidity of the stomach, it is necessary to observe a break between doses of at least two hours.

In the case of uncontrolled intake of antibiotic drugs, an overdose may occur, a symptom of which is nausea, sometimes turning into vomiting, diarrhea, and hearing may be temporarily lost.

Treatment of an overdose should begin immediately with gastric lavage and further symptomatic therapy.

Azithromycin preparations are removed in two stages:

Elimination half-life within 14 - 20 hours, 8 - 24 hours after taking the drug.
Complete elimination within 41 hours, 24 - 72 hours after taking the drug.

The long period of elimination of the drug is due to its use once a day. In the hearth inflammatory process the antibiotic persists up to 7 days after the last dose taken, which determines the effectiveness of a short course of therapeutic therapy.

Purpose this antibiotic and its required dosage is produced only by a specialist, with a mandatory preliminary determination of the sensitivity of the microflora that caused the disease in a patient to the prescribed drug.

YOUR FAMILY CANNOT GET FREE FROM PERMANENT ILLNESS?

Do you and your family get sick very often and are treated with antibiotics alone? Have you tried many different medicines, spent a lot of money, effort and time, but the result is zero? Most likely, you are treating the effect, not the cause.

Weak and reduced immunity makes our body DEFECTIVE. It cannot resist not only infections, but also pathological processes that cause TUMORS AND CANCER!

We urgently need to take action! That is why we decided to publish an exclusive interview with Alexander Myasnikov, in which he shares a cheap method of strengthening immunity.

The off-season is the time of epidemic outbreaks of colds and exacerbation of chronic infections. The modern dynamic rhythm of life does not allow you to get sick for a long time, so an antibiotic for three days, effective against inflammation of the upper respiratory tract, has gained popularity.

Azithromycin

This is the name of the drug that allows you to quickly get rid of respiratory diseases. .

It is an antibiotic, three tablets of which make up the full course of treatment.

Operating principle

The drug has a bacteriostatic effect, that is, it stops the development of pathogens. This happens due to the introduction of the active substance into the cell, attaching to its ribosomes and blocking the synthesis of the protein necessary for growth. With an increase in concentration, the drug acquires bactericidal properties, killing the pathogen. The therapeutic effect develops within the first 2 hours after ingestion and lasts about a day.

An antibiotic course of 3 tablets is active against the following intra- and extracellular pathogenic bacteria:

gram-positive streptococci that cause pneumonia, scarlet fever, endocarditis, rheumatism, postpartum blood poisoning, nephritis, inflammation of the larynx, epidermis and soft tissues;
pneumococci, which inflame the lungs, middle ear, paranasal sinuses and meninges;
Staphylococcus aureus - the causes of a wide variety of diseases (from aesthetically unpleasant acne to deadly sepsis and meningitis) and persistent nosocomial infections;
gram-negative legionella, gardnerella, gonococci, haemophilus influenzae and whooping cough, chlamydia, mycoplasmas and pale treponema.

Microorganisms resistant to erythromycin are also resistant to azithromycin.

See also: All about resistance and methods for determining the sensitivity of bacteria to antibiotics

A bit of history

The promise of a new class of ABP inspired scientists to further develop and create more effective medicines. The latest achievement in this direction was Azithromycin, which surpasses erythromycin in acid resistance by almost 300 times.

Antibiotic three tablets per pack: name, analogues, application

As a confirmation of the reliability of the list, we attach a photo gallery with these medicines.

All drugs included in the list have a similar effect and general rules for taking.

Indications

The drug Azithromycin is produced in different dosage forms: there are granules from which a suspension is prepared, special powders for injection solutions, a lyophilisate. However, the most popular type of antibiotic is three capsules or tablets that make up a complete course of treatment for respiratory infections of the respiratory system.

To cure a mild form of sinusitis, pharyngitis and laryngitis, you need to take 1 tablet of 0.5 g every 24 hours for three days (1 hour before or 2 after a meal). With otitis media, moderate sinusitis, tonsillitis and scarlet fever, a five-day course is indicated. The duration of therapy for NDP infections depends on the severity of the disease and the sensitivity of the pathogen.

The dosages given indicate how adults should take azithromycin. For children, the required amount of medicine is calculated based on their weight. So, for every kilogram of body weight of a child, there should be 10 -5 mg of the active substance, depending on the duration of the course (3 or 5 days). Most often, in this case, powders or granules are prescribed, from which a suspension is prepared. In addition, there are a number of age restrictions for certain dosage forms.

Contraindications

With caution, 3 tablets of an antibiotic called Azithromycin or another brand name are prescribed during pregnancy. Despite the low toxicity, there is no complete information about the safety of macrolides for a developing fetus. In this regard, the drug can be used by pregnant women only when the undoubted health benefits of the expectant mother are higher than the potential harm to the child. With antibiotic therapy during lactation, treatment is carried out strictly under the supervision of the attending physician, if necessary (long course), it is recommended to stop breastfeeding for a while, expressing milk.

Side effect

The low toxicity of Azithromycin and analogues determines the incidence of side effects.
Dysbacteriosis and allergy characteristic of taking antibiotics are observed in less than 5% of cases.
Even less often there are violations of the activity of the heart, nervous and genitourinary systems. For example, dizziness, tachycardia and candidiasis develop in only 1% of patients.

Antibiotic therapy for influenza and respiratory diseases

Main article: When to use antibiotics for influenza in adults and children

Self-medication is unacceptable for several reasons:

All antibacterial drugs are designed to fight infections caused solely by bacteria, as the name suggests. That is, with a cold or flu caused by a virus, ABPs simply will not help. Moreover, side effects worsen the general condition and often provoke complications.
Despite a very wide range of antimicrobial action, an antibiotic for 3 days called Azithromycin or its analogues is not at all a panacea for infectious diseases. It is likely that the inflammation was caused by a strain resistant to this agent. In this case, as in the previous one, treatment will only bring harm.
Only a doctor can reliably determine the pathogen and prescribe adequate therapy. This is done on the basis of the results of a laboratory study that provides information about the specific bacterium that caused the disease.
Again, only a specialist is able to choose the optimal antibiotic therapy regimen, taking into account contraindications, the age of the patient and his individual characteristics.

Influenza and colds are treated with antiviral medicines, bed rest and symptomatic remedies (antipyretic tablets, cough syrups and drops for the common cold).

Find a doctor near you

Pain in the abdomen - in 3% of cases;
Nausea - in 3% of cases;
Inflammation of the kidneys - in 1% of cases;
Chest pain - in 1% of cases;
Dizziness, headache, drowsiness - in 1% of cases;
In children, sleep disorders, neuroses - in 1% of cases;
Allergic reactions - in 1% of cases.

Find out also:

How to choose the right antibiotic for angina?
What antibiotics are prescribed for follicular angina?

Read also:

Azithromycin for purulent tonsillitis is prescribed in most cases for a 5-day, less often - for a 3-day treatment regimen. In the first case, the patient takes ...

To date, Sumamed with purulent sore throat is among the first-line drugs of choice. It is very effective, quite safe, releases …

An antibiotic that is sometimes mistaken for flu and colds, 3 tablets per pack, is azithromycin. It can be sold under different trade names…

When there are signs of acute tonsillitis, doctors immediately prescribe antibiotics - with angina it is vital necessary remedy capable of destroying the infection. sore throat, fever, unpleasant pain when swallowing are characteristic symptoms illness. The cause of the disease is often pathogenic bacteria - streptococci and staphylococci.

Even 150-200 years ago, tonsillitis could have been fatal. Nowadays, humanity is saving a lot of antibacterial drugs released to combat infectious agents. What antibiotics to take for angina in adults in order to quickly return to good health and performance, and how to cure the disease without antibiotics? Consider the possible options used by doctors when prescribing therapy.

Acute tonsillitis is an insidious disease. Usually it is characterized by elevated body temperature up to 38-39 degrees. At the same time, there are no symptoms of a cold in the form of a cough or runny nose. There is a characteristic pain when swallowing, lymph nodes increase, health worsens. However, the most characteristic sign for streptococcal or staphylococcal angina is the defeat of the tonsils, the degree of which may be different:

with the catarrhal form of tonsillitis - swelling and redness (often without fever);
with follicular - the so-called picture of the starry sky, formed from white-yellow purulent nodules formed under the mucosa;
with lacunar - fibrinous-purulent plaque;
with ulcerative membranous - a grayish-yellow coating, under which superficial ulcers form.

Doctors, as a rule, accurately diagnose acute tonsillitis. To prescribe the necessary antibiotics for purulent sore throat in adults, it is advisable to take a smear of mucus or pus from the surface of the tonsils. This will allow you to identify the specific causative agent of the disease. The realities of our reality are such that not every clinic conducts such an analysis. Often, the state institution does not have the funds for this. In addition, it will take 3-4 days to sow microflora with a standard procedure, and you need to act immediately. How to treat angina in this case? In order not to delay, doctors prescribe an antibiotic for purulent tonsillitis of a wide spectrum of action.

The total number of antibacterial drugs is large, they are conditionally divided into several groups:

penicillins;
macrolides;
fluoroquinolones;
cephalosporins;
tetracyclines.

Treatment of acute tonsillitis involves the use of penicillins or macrolides. Any medicine from each group has its own indications for use, daily dosage and contraindications. Therapy with this or that drug should take place with the consent of the doctor, otherwise the wrong remedy (on the advice of friends or a pharmacist) can provoke serious complications.

In acute tonsillitis, antibacterial agents are usually prescribed in tablets. Treatment of angina with antibiotics in adults by injection is practiced only in hospitals. Now injections for angina are rarely used, because modern drugs are almost completely absorbed from the gastrointestinal tract into the systemic circulation.
Note! In order to avoid resistance (resistance) of infectious agents to antibiotics, tonsillitis cannot be treated with the same drug if less than 2 months have passed since the last application. In addition, when the sore throat does not go away and there is no improvement in the patient's well-being after 3 days from the start of therapy, the prescribed antibiotic should be replaced with another one, agreed with the doctor.

Most often, antibiotics are prescribed for angina of the penicillin series. This is due to the small number of side effects and sufficient sensitivity of pathogenic bacteria to the active substance. Medicines of the penicillin series against angina make up a large group. Consider the most effective antibiotics for the treatment of the disease.

This inexpensive drug effective against gram-positive and gram-negative cocci. It is prescribed for tonsillitis, infections of the respiratory tract, ENT organs and the oral cavity. These antibiotics for angina in adults are used at a dosage of 2-4 tablets 3-4 times a day. For children, the daily dose is calculated according to the age and body weight of the child.

There are analogues of phenoxymethylpenicillin for the active substance:

Cliacil;
smallpox;
Penicillin Fau;
Fau-cillin;
V-penicillin.

The medicine is safe for pregnant and lactating women, but can cause redness of the skin, urticaria, rhinitis, conjunctivitis, dry mouth, diarrhea, loss of appetite.

Antibiotics for angina, containing amoxicillin as the active substance, are prescribed most often. This is due to the effectiveness of the drug and a wide spectrum of action. The drug is available in capsules or tablets containing 250, 500 or 1000 mg of amoxicillin. The pharmacy can offer analogues for the active substance, the list of which is quite large:

Gramox-A;
Amoxicar;
Ospamox;
Amoxil;
Hyconcil;
Flemoxin Solutab;
Ecoball.

With angina, an adult is recommended to drink 2 tablets of 500-1000 mg per day, between which 12 hours should pass. The exact dosage and course of therapy is determined by the attending physician, depending on clinical picture diseases. Amoxicillin taken orally is rapidly absorbed, regardless of food intake. Of the contraindications noted hypersensitivity to penicillin, pregnancy and lactation.

This drug is a combination of two active substances - amoxicillin and clavulanic acid. The combination of these components enhances the antibacterial effect of the drug, but also has various side effects on the digestive and nervous system, provokes allergic reactions. Doctors believe Augmentin a good remedy against strains of staphylococcus, streptococcus, echinococcus and other pathogenic bacteria. Known analogues of Augmentin:

Amoxiclav;
Medoklav;
Flemoklav Solutab;
Ecoclave.

Please note: Medicines in this group are expensive, so let the doctor tell you which antibiotic to drink for angina. Perhaps, in your particular case, cheaper medicines will be effective.

Macrolide antibiotics are not as toxic compared to penicillin drugs, do not have serious side effects and are well tolerated by patients. It is safe to drink these antibiotics with angina not only for adults, but also for children.

Erythromycin laid the foundation for the entire group of macrolides about 70 years ago. But to this day it is used as an antibacterial agent for purulent tonsillitis, pneumonia, bronchitis, diphtheria, otitis media, sinusitis and other infections caused by pathogens sensitive to the active substance.

From angina, adults are prescribed 250-500 mg of erythromycin 4 times a day with an interval between doses of 6 hours. How long you need to take these antibiotics for angina in an adult in tablets, the attending physician will accurately determine, taking into account the clinical picture.

Azithromycin has a wide spectrum of action against pathogenic microflora. Indications for use: purulent tonsillitis, bronchitis, pneumonia, scarlet fever and infections of the upper respiratory tract. Some patients believe that this is the best antibiotic for angina. Indeed, with a moderate severity of the disease, it is enough to buy a package in which there are only 3 tablets of 500 mg of azithromycin. The instructions for the drug describe how to take antibiotics for follicular tonsillitis and other pathologies. There are 2 reception schemes:

500 mg of azithromycin for 3 days.
500 mg on the first day of treatment, 250 mg on the next 4 days.

Azithromycin is also sold under other names:

Azitrox;
AzitRus;
Zitrolide;
Summed;
Ecomed.

Please note: Is it possible to treat angina with Azithromycin in a particular case, the doctor will accurately determine. If so, take the medicine at the same time of day. At the same time, drink it 1 hour before a meal or 2 hours after a meal.

Another antibiotic for the treatment of angina. It has many analogues containing the same active ingredient:

Aziklar;
Clubax;
Clarkt;
Clarithromycin;
Clarilide;
Clarimed;
Clarimycin;
Klacid;
Lecoclar;
Flomilide.

These antibiotics are prescribed for adults at 250-500 mg every 12 hours. The course of therapy is 1-2 weeks.

Many patients are not sure if antibiotics are needed for acute tonsillitis. Their doubts are understandable, because the drug harms the body. To the question "is it possible to cure a sore throat without antibiotics?" there is no single answer - it all depends on what caused the infection.

Treatment of angina without antibiotics passes if the culprits of the disease are viruses or fungi:

Viral tonsillitis.

The disease is provoked by Coxsackie, influenza and adenoviruses. With this pathology, angina is treated without antibiotics, but with the use of antiviral and anti-inflammatory drugs.

Fungal form of tonsillitis.

It develops against the background of active reproduction of fungi of the genus Candida. Treatment with antibiotics is not prescribed, but antifungal drugs of local and systemic action are used.
Please note: An illness without antibiotics is not treated if it is caused by a bacterial infection! And what antibiotics to treat the disease and how many days to take the prescribed medicine, only a therapist or an otolaryngologist will say. With all the richness of the choice of medicines, self-medication is fraught with serious consequences.

It is necessary to treat angina in a complex way - antibiotics and drugs local action. Treatment of acute tonsillitis in adults at home involves frequent gargling (at least 5-8 times a day) with antibacterial compounds:

a warm solution of table salt (1 teaspoon per 1 glass of water);
solution baking soda(1 teaspoon per 1 glass of water) with the addition of 2-3 drops of iodine.

Rather, lozenges and sore throat tablets for resorption help to cure tonsillitis:

Grammidin;
Lizobakt;
Dorithricin;
Septolete;
Trachisan;
Strepsils;
Streptocid;
Pharyngosept.

In addition to tablets and lozenges, a sore throat spray with an antibiotic is prescribed. Medicines in the form of aerosols are widely represented in the pharmacy network:

Angilex;
Hexoral;
Ingalipt;
Stopangin;
Tantum Verde.

If it is not possible to buy an expensive throat spray, you can lubricate the tonsils with Lugol solution 2-3 times a day, which costs a penny.
Please note: Some sources recommend Bioparox spray. This drug has been banned from sale and use since 2016 due to an increase in serious side effects, including life-threatening anaphylactic reactions.

Drinking antibiotics for sore throat is vital if the cause of the disease is a bacterial infection. After antibiotics or in parallel with them, it is desirable to drink a course of probiotics to restore the normal microflora of the gastrointestinal tract. If you treat angina in adults in a complex way, then the disease will pass in a week.

Article rating:

Advantages:
effect, short course

Flaws:
side effects, contraindications

Year of manufacture/purchase:

General impression.

Side effects of Flemoxin:

allergic reaction;
diarrhea;
pseudomembranous colitis;
hemolytic anemia;
angioedema.

disruption of the liver.

angioedema;
rash;
constipation or diarrhea;
physical weakness;
bloating,
insomnia;
exhaustion.

allergy to penicillins;
pregnancy;
jaundice.

eosinophilia;
skin rash;
anaphylactic shock;
fever
serum sickness;
dizziness;
nausea;
flatulence;
stomatitis.

Adverse reactions of Sumamed:

diseases of the liver and kidneys;
lactation.

intestinal disorders;
nausea;
headache;
weakness.

The antibiotic azithromycin is used in 3 tablets for angina, and therefore all preparations based on it: Azitrox, Sumamed, Azimed, Hemomycin, Azivok and others.

Perhaps this is the only antibiotic that is used for angina with a course less than the standard 10-12 days. Perhaps that is why most of the patients prefer to use it. At the same time, there is no noticeable difference between the efficacy and safety of azithromycin and other antibiotics (the same erythromycin, penicillin group drugs).

Like all other macrolides, azithromycin with a high frequency of disruption of the gastrointestinal tract due to the suppression of active bacteria in the intestine and the development of dysbacteriosis. This manifests itself in the form of diarrhea, changes in stool consistency, nausea, and rarely vomiting.

Despite the convenient scheme of application, azithromycin has its drawbacks - for example, its effect on the gastrointestinal tract

This is partly why azithromycin is prescribed for angina in situations where the patient has expressed intolerance to safer β-lactam antibiotics, in particular, amoxicillin, benzathine-penicillin, phenoxymethylpenicillin. If there is no such intolerance, doctors prefer to prescribe traditional penicillins or cephalosporins, which are less likely to cause side effects from the digestive system.

On the other hand, if a doctor has to choose among macrolide antibiotics, he prefers azithromycin, since the famous erythromycin causes digestive disorders even more often, and josamycin is much more expensive.

3 antibiotic tablets for angina are prescribed only for adult patients. The fact is that for children, azithromycin is available in the form of a powder for the preparation of a suspension and it is irrational to prescribe tablets to them.

Each tablet of the remedy is taken once a day either one hour before or 2 hours after a meal. It can be drunk with clean water. Accordingly, three antibiotic tablets are drunk in three days, after which the sore throat is treated only symptomatically. Attempts to supplement the use of azithromycin for angina with other antibiotics are dangerous because they can cause the development of fungal diseases.

Possible schemes for taking azithromycin (the second - for 5 days - is preferable and more effective)

Another treatment regimen is that 3 tablets of azithromycin for angina are taken for 5 days. To do this, the first tablet is drunk on the first day as a whole, the remaining two are divided into two parts each and half is drunk per day. As a result, they are enough for another 4 days of admission.

Practice shows that the regimen of taking azithromycin for three days is less effective than using it for 5 days or using other macrolides for longer courses. With it, the development of complications of angina occurs more often, from which the medicine should protect. Therefore, if possible, this medicine should be drunk for exactly 5 days, and the three-day regimen should be switched only with the obvious development of side effects and the need to end treatment as soon as possible.

Today, statistics on the incidence of various side effects when using azithromycin are collected and well known:

Diarrhea - in 5% of cases (especially often with a three-tablet scheme);
Pain in the abdomen - in 3% of cases;
Nausea - in 3% of cases;
Flatulence, vomiting - in 1% of cases;
In children, constipation, gastritis - in 1% of cases;
Fungal lesions of the oral cavity (including fungal tonsillitis) - in 1%; cases;

Candidiasis oral cavity and throat - a common side effect with intensive use of antibiotics

Depending on the severity of these side effects, your doctor may prescribe additional funds or change the antibiotic. It is likely that when taking the same Vilprafen, no side effects will appear, although the remedy itself is intended to be taken for at least 10 days.

It is because of the possibility of side effects that azithromycin is not recommended for pregnant women and breastfeeding mothers. It is forbidden to be taken by patients with impaired liver and kidney function. Children under 16 years of age are not prescribed azithromycin tablets. For them, there are preparations of this agent on sale in the form of powders for the preparation of oral suspensions.

When treating a nursing mother with azithromycin breast-feeding may have to stop for a while

Three tablets per course for angina, only the antibiotic azithromycin is used;
If possible, it is desirable to replace azithromycin with penicillin preparations;
If possible, three tablets of the remedy are taken for 5 days, not three. In this case, the effectiveness of treatment increases.

Sources: />

Every person at least once in his life, but had to take antibiotics, because there comes a moment when to be cured folk remedies or simple antiviral drugs do not work, complications begin. One of the most famous broad-spectrum antibiotics is Azithromycin (500 mg).

"Azithromycin" (500 mg of the active ingredient in each tablet) can be purchased at any pharmacy, however, you need to get a prescription from a doctor.

As mentioned above, this is a broad-spectrum antibiotic, due to its components it has positive impact, namely, killing gram-positive and gram-negative bacteria, which most often cause all ailments. The main active ingredient in it is azithromycin.

It is effective against staphylococcus, streptococcus, legionella, gardnerella, ureaplasma, treponema and many others. That is why antibiotics are prescribed for various diseases, when there is an exact certainty that the pathogen belongs to the list of the above.

A very convenient release form for the drug "Azithromycin-500". 3 tablets are contained in a package. It is this amount that is enough for a full course of treatment, since it is considered a very strong drug. It is recommended to take it only after the appointment of the attending physician.

Separately, it must be said that "Azithromycin" (500 mg, 3 tablets) is very well absorbed in the gastrointestinal tract, and that is why it is quickly distributed throughout the body. Because of what such a positive effect is achieved, and the improvement occurs within three days.

If we talk about the withdrawal of the drug, then approximately 60 percent is excreted in the bile (unchanged) and about 40 percent in the urine.

Separately, it must be said about when it would be appropriate to purchase exactly "Azithromycin-500" (3 tablets). According to the International Classification of Diseases, an antibiotic can be used if the following diseases are present:

otitis of varying degrees, when the risk of developing complications increases, as a result of which a person may lose hearing;
sinusitis, and it is the acute stage of the disease;
acute laryngitis, when there is a possibility of the disease moving into a chronic stage; and as you know, chronic laryngitis is dangerous by the degeneration of cells into cancer cells;
pharyngitis and tonsillitis, which have developed due to the negative effects of streptococcus;
pneumonia, especially when the pathogen is unknown;
bronchitis, both in the acute and chronic stages;
skin diseases, when pustular formations appear on it;
urinary tract infections in both men and women.

Due to the fact that the effect of the drug "Azithromycin" (500 mg) extends to almost all pathogens, it is prescribed by doctors to treat diseases such as:

infectious and inflammatory diseases of the nasopharynx, including tonsillitis, tonsillitis, laryngitis;
infectious and inflammatory diseases of the ears, such as otitis media;
respiratory infections that provoke diseases such as bronchitis and pneumonia;
damage to soft tissues and skin in humans, such as dermatitis, erysipelas;
diseases of the genitourinary system (urethritis);
diseases of the stomach, in particular ulcers and gastritis, which are caused by the negative and destructive effect of such bacteria as Helicobacter pylori.

Most often, the doctor prescribes Azithromycin for adults - 500 mg tablets (3 pieces per pack), because the effect comes much faster, and you only need to drink them for three days.

It should be remembered that you need to take only one tablet once a day and in no case should you drink everything at once, hoping that the effect will be instantaneous. This will only aggravate the condition.

Despite the fact that Azithromycin tablets (500 mg) are considered a universal drug to fight various infections and bacteria, not everyone can use them.

There are a number of restrictions when a person is strictly forbidden to be treated with this particular antibiotic:

hypersensitivity to the components of the drug, both auxiliary and main;
kidney failure, because the drug must be stably excreted from the body, and 40 percent is in the urine;
liver failure;
age up to 12 years.

In addition to the fact that the drug is strictly forbidden to take in the presence of the above diseases, it is not recommended to use the following categories of people:

pregnant women;
children over 12 years of age who have kidney problems;
people with arrhythmias.

In these cases, it should be used with caution and only when the effect of the antibiotic is much higher than the possible side effects.

"Azithromycin", 500 mg (3 tablets) can provoke a number of side effects, which include the following:

problems with the gastrointestinal tract, namely nausea, upset stool, pain in the abdomen;
allergies, namely skin itching and rashes;
headache, less often dizziness and weakness;
problems from the genitourinary system, namely vaginitis, nephritis.

Very rarely, patients taking Azithromycin (500 mg) may develop side effects such as bleeding disorders, hyperglycemia.

Separately, we need to talk about the fact that Azithromycin does not always interact well with other drugs:

enhances the effect of "Warfarin";
when using "Digoxin" there is a risk of developing glycoside intoxication;
when used with "Disopyramide" there are cases when ventricular fibrillation began;
when using "Rifabutin" there is a risk of developing leukopenia.

Also, with the simultaneous use of "Cyclosporine" and "Azithromycin", the risk of side effects increases, namely from "Cyclosporine".

Due to the fact that immunity in pregnant women is significantly weakened, the likelihood of bacteria and microbes entering the body increases, which must be fought with antibiotics.

"Azithromycin" (500 mg) is allowed to be used by pregnant women and breastfeeding women only if the benefit to the mother is greater than possible harm for a child. Otherwise, a safer antimicrobial agent must be selected.

Some people who take the drug without a doctor's prescription often do not comply with the dosage. And so they begin to develop all the relevant symptoms, which include severe nausea, sometimes even vomiting (it all depends on how the person perceives the discomfort), hearing loss (both partial and complete), diarrhea.

When such symptoms appear, it is urgent to carry out a gastric lavage and stop the symptoms, because otherwise the antibiotic will cause great harm to almost all organs.

The cost of the drug is very democratic, depending on which pharmacy it is purchased from, it can vary from 100 to 200 rubles.

To date, there are no cheaper analogues of Azithromycin. One can only say that there is a more expensive drug, such as Sumamed, which has exactly the same composition, but the price is no longer 100 or 200 rubles, but about 600.

Turning to the pharmacy, many patients are faced with the fact that pharmacists are trying to sell Sumamed, even if they ask for Azithromycin, justifying this best effect. In fact, these are two absolutely identical drugs produced in different countries.

Among the positive aspects regarding the antibiotic "Azithromycin", according to consumers, we can distinguish:

affordable price;
ease of use, since the number of capsules in the package is just designed for a full course of treatment;
fast action: already on the second day after the start of administration, patients notice an improvement in their condition.

Not all patients agree that Azithromycin (500 mg) is an almost universal drug, since in some cases it did not help.

But one thing should be noted: all doctors say that if a course of antibiotic treatment has been started, they must be drunk to the end. And in the event that the course was interrupted, then the next time after the appointment of the same drug, there will be no effect, because the bacteria have already become resistant to it.

Before starting treatment with the drug, you need to consult with your doctor so that he issues a prescription. Because today, most pharmacies do not sell it without a prescription due to the fact that some patients take the drug off-label.

Acute tonsillitis is an infectious and inflammatory disease characterized by damage to the lymphatic pharyngeal ring and is accompanied by fever, general intoxication, sore throat and the presence of purulent effusion on the tonsils.

The high risk of rheumatic complications in the heart and joints explains the fact that antibiotics for angina are the main treatment.

The peak incidence occurs in the autumn-winter period. Children get sick more often than adults. After fifty years, there is a decrease in the body's susceptibility to the main pathogens of tonsillitis.

The disease has airborne droplets (transmission of the pathogen by coughing, sneezing) and contact-household (common utensils) transmission mechanisms. For herpetic infection (enterovirus infection caused by Coxsackie viruses), the fecal-oral route of infection is characteristic.

The most common sources of infection are:

patients with tonsillitis in the acute period;
chronic carriers of staphylo- and streptococci;
patients with streptococcal impetigo;
patients with bacterial infection of the respiratory tract;

Fungal tonsillitis, as a rule, occurs in people with immunodeficiencies. They can occur due to the activation of opportunistic flora or after using household items after infected patients.

The main causative agents of the disease are:

group A beta-hemolytic streptococci;
pneumococci;
golden staphylococci;
adenoviruses;
coxsackie viruses;
candida albicans;
spirochetes;

The gold standard for the treatment of streptococcal tonsillitis are aminopenicillins and cephalosporins.

In the presence of purulent complications, lincosamides are prescribed.

For parenteral administration, the following are preferred:

Ceftriaxone;
Cefoperazone;
Ceftazidime;
Cefepime;
Ampicillin/sulbactam.

In the acute period, it is advisable to prescribe penicillins with an extended spectrum of activity (Ampicillin, Amoxicillin) and inhibitor-protected drugs (Amoxicillin / clavulanate, Ampicillin / sulbactam). In moderate disease, oral cephalosporins (Cefixime and Cefuroxima-axetil) are also highly effective.

In severe tonsillitis or moderate tonsillitis with severe symptoms of intoxication and high fever, third and fourth generation cephalosporins are prescribed for parenteral administration.

To prevent complications after the end of the main treatment, bicillin prophylaxis is carried out. Bicillin-3 is administered intramuscularly, with an interval of seven days, three times.

Bicillin-5 is prescribed intramuscularly once (not used in young children).

It is a second-generation cephalosporin drug. The active ingredient is Cefuroxime.
It has a wide spectrum of antimicrobial activity, including gram-positive microorganisms resistant to penicillins (excluding methicillin-resistant strains). Effective against beta-hemolytic streptococci. Active against gram-negative flora with resistance to ampicillin.

Main article: Instructions, analogues and reviews about Zinnat

It is contraindicated in the period up to three months of life, it is not prescribed for premature babies and weakened, emaciated patients. It is also not recommended for pregnant women (may be prescribed only if the benefit to the mother outweighs the possible risk to the fetus) and breastfeeding.

Not used in patients with a history of allergic reactions to cephalosporins and penicillins. In the presence of renal insufficiency, ulcerative colitis, Crohn's disease.
It is important to remember that cefuroxime is not administered simultaneously with aminoglycosides and loop diuretics, due to the high risk of nephrotoxicity.
Side effects include allergic reactions, dyspeptic disorders, dysbiosis, thrush.

For infections medium degree severity, adults are prescribed 250 mg twice a day. At serious illness it is possible to increase the dose to 500 mg twice a day.

For children from three to six months, use 40-60 mg / kg 2 times a day. Older than 6 months but younger than 2 years 60 to 120 mg every 12 hours. After two years, 25 mg of the drug with an interval of twelve hours.

Duration of admission depends on the severity of the disease.

The standard course of antimicrobial therapy is seven days.

If necessary, antibiotics for purulent sore throat are used for up to ten days. A three-day appointment of azithromycin is advisable only as a prophylaxis for rheumatism, in case of an allergy to natural penicillins.

We present the trade names of the best antibiotics for angina in adults in the list:

Erythromycin

Main article: Erythromycin instructions for use

Belongs to the class of fourteen-membered macrolides. It has a pronounced bacteriostatic effect on pathogens, due to a violation of the formation of peptide bonds and blocking the synthesis of proteins. In the case of high dosages, the drug may exhibit a bactericidal effect.

These antibiotics are prescribed only in the presence of individual intolerance or other contraindications to the appointment of penicillins and cephalosporins.

The spectrum of activity includes most representatives of Gram+ and Gram-flora. Shigella, Salmonella, Enterobacter and Bacteroides are resistant to erythromycin.

Trade names of antibiotics with erythromycin used for purulent tonsillitis in adults:

Erythromycin;
Ermiced;
Eomycin;
Ilozon;
Grunamycin.

are fairly cheap antibiotics for sore throats.

Grunamycin

It has a release form for oral and parenteral use, it is also used in the form rectal suppositories. It is effective not only for the treatment of acute diseases of the upper respiratory tract, but also for the prevention of rheumatic complications caused by streptococcal infection.

The drug is contraindicated:

patients taking terfenadine or astemizole (antihistamines);
in the presence of hypersensitivity and individual intolerance;
patients with severe cardiac arrhythmias, severe hearing impairment, renal or hepatic insufficiency;
during lactation.

It is also important to remember that antibiotics for purulent tonsillitis containing erythromycin estolate are not prescribed to pregnant women and are not recommended for newborns, due to the high risk of pyloric stenosis.

For children over fourteen years of age and adult patients, a single dose is from 250 to 500 mg. Grunamycin is applied four times a day, at intervals of six hours. The recommended daily dose is 1-2 grams. The maximum allowable dose is four grams per day.

Intravenously, the agent must be administered in a stream, slowly over five minutes or drip.

Patients from four months to eighteen years of age are prescribed 30-50 mg / kg per day, divided into 2-3 injections (receptions). Babies, up to three months of life, are prescribed 20-40 mg / kg per day.

For rectal use (suppositories), appoint 400 mg per day from the age of one year to three years, 500-750 mg from 3 to six years and per gram from six to eight years. The daily dosage is divided into 4-6 times.

Erythromycin reduces the effectiveness of the use of beta-lactams. Enhances toxic effects on the kidneys during cyclosporine therapy. Reduces the effectiveness of hormonal contraceptives.

It is categorically incompatible with terfenadine and astemizole due to the high risk of severe cardiac arrhythmias. It also exhibits antagonistic interaction with clindamycin and chloramphenicol preparations.

Azithromycin is a semi-synthetic fifteen-membered macrolide from the azalide group.
Has a lower risk of side effects and unwanted drug interactions, good tolerance. In short courses of 3 tablets, this antibiotic for angina is used only after the end of the main treatment in order to prevent rheumatic complications in case of intolerance to penicillins (bicillin-3 and -5).

For the treatment of an acute disease, it is used in courses lasting 7-10 days.

Trade names:

Azithromycin
Sumamed;
Azitrus.

Effective as additional method treatment against the background of systemic antimicrobial therapy. Not prescribed as monotherapy.

A throat spray with an antibiotic for sore throats can only be used after the age of three years, because, due to the essential oils included in the aerosols and sprays, there is a high risk of laryngospasm in young children.

The active active ingredient of the drug are soluble sulfonamides and essential oils mint and eucalyptus.

It has anti-inflammatory, antibacterial and antifungal effects. It also has a mild analgesic effect. The spectrum of activity covers gram-positive and gram-negative flora, fungi of the genus Candida.

Spray from a sore throat with an antibiotic is not used in the presence of individual intolerance to the components of the drug.

Side effects include burning in the throat, perspiration, allergic reactions.

Ingalipt is used up to four times a day, spraying the spray in the mouth for 1-2 seconds, after rinsing the mouth with warm boiled water.

Main article: Instructions for use of Ingalipt

With antiseptic action. Cameton

It is a combined medicine that has a pronounced antiseptic and anti-inflammatory effect due to the content of chlorobutanol. It also has a moderate analgesic effect due to the action of camphor, menthol and eucalyptus oil.

Contraindications to the appointment of Kameton include children under five years of age and individual intolerance.

The agent is sprayed into the oral cavity, followed by inhalation for two seconds. Such inhalations are used up to four times a day.

It has a pronounced anti-inflammatory and analgesic effect, relieves swelling of the mucosa, stabilizes the permeability vascular wall capillaries, due to the content of benzydamine (non-steroidal anti-inflammatory).

It is not prescribed for patients with individual intolerance to the components. Lozenges are used with caution in women during pregnancy and lactation.

Tablets dissolve one by one 3-4 times a day.

Spray for adults is used every 2-3 hours, making 4-8 clicks on the sprayer. For children from six to twelve years old, four sprays are prescribed. Up to 6 years, 1 spray is prescribed for every 4 kilograms of weight, not exceeding the total dose of 4 sprays.

Usage antihistamines helps reduce risk allergic reactions on the drugs used, and also help to reduce the swelling of the mucosa and reduce the permeability of the capillary wall (Cetrin, Loratadin, Zodak, Zirtek, Tavegil).

To speed up recovery, increased dosages of vitamin C are used (for adults, up to 2 grams per day, the first three days, with a gradual decrease to 500 mg). After recovery, a course of multivitamins is indicated.
For patients with cardiopathies, rhythm disturbances, etc. it is advisable to add cardiotrophic therapy (Riboxin, Elkar).
The use of physiotherapeutic agents (UVI, UHF, ultrasound) is effective.

With frequent tonsillitis, it is necessary to carry out bicillin prophylaxis twice a year: in spring and autumn.

Surgical treatment is indicated in the presence of purulent complications (abscess, lymphadenitis) and consists in opening and draining the focus, followed by washing with solutions of antiseptics and antimicrobials. Systemic treatment with lincosamides is also prescribed.

Tonsillectomy is used for chronic decompensated tonsillitis.

To answer the question: « How to cure a sore throat without antibiotics in an adult? - it is necessary to analyze the etiology of non-streptococcal tonsillitis.

Herpetic a. begins with a flu-like syndrome (weakness, fatigue, fever, chills). Then there are sore throats, profuse salivation, symptoms of rhinitis. On examination, a bright hyperemia of the arches, posterior pharyngeal wall, tonsils and uvula, abundant blisters filled with serous contents are visualized. Small punctate hemorrhages on the mucosa are possible. Depending on the course of the disease, the elements of the rash either suppurate or open, forming shallow ulcers and erosion.

Antibiotic treatment of angina caused by enterovirus infection is necessary only in severe cases with a high risk of activation of the secondary bacterial flora.

Basic therapy for mild and moderate forms includes:

antihistamines;
oroseptics, and further means that accelerate epithelialization;
immunomodulators;
antiviral drugs;
antipyretic;
measures to relieve symptoms of intoxication;
bed rest;
a sparing diet to exclude additional trauma to the mucosa;
multivitamins;
probiotics.

For pharyngomycosis, yellowish-white multiple plaques are indicative, spreading to the tongue, arches and buccal mucosa. There is an unpleasant smell from the mouth, a perversion of taste.

As a rule, they develop:

against the background of immunodeficiency states;
in smokers;
patients receiving long-term therapy with hormonal inhalation drugs (asthmatics);
in persons using dentures.

Antibiotics for angina caused by fungi are not prescribed.

Therapy consists in the appointment of systemic antifungal drugs, the use of oroseptics, gargling with antiseptic solutions, treating affected areas, prescribing immunostimulants, multivitamins, probiotics. Drinking plenty of fluids and bed rest are also recommended.

Main symptoms

Classical streptococcal tonsillitis is characterized by a common onset with an increase in temperature up to 39-40 degrees, the severity of general intoxication symptoms (weakness, lethargy, muscle and joint pain, nausea). Patients complain of sore throat, aggravated by swallowing, talking. On examination, a bright hyperemia of the arches, uvula and posterior pharyngeal wall is revealed. The tonsils are enlarged. The abundance of purulent effusion depends on the severity of the disease.

The condition of the tonsils with angina: an increase in size, purulent plaque.

The submandibular and cervical lymph nodes are enlarged (1-1.5 cm), densely elastic, mobile, not soldered into conglomerates. As a rule, painless or moderately sensitive to palpation.

Antibiotics for purulent sore throat should be used from the first days of treatment, this will avoid early and late complications.

An increase in lymph nodes up to two or more centimeters, redness of the skin above them and severe pain indicate the addition of lymphadenitis. Palpable softening of the node is an indicator of its purulent fusion and requires surgical treatment.
Increasing pain in the throat, spasm of the masticatory muscles, unbearable temperature and unilateral sharp protrusion of the tonsil indicate the development of a paratonsillar abscess. Treatment of purulent tonsillitis complicated by an abscess is carried out with antibiotics of the lincosamide group (Clindamycin), after opening and draining the septic focus.

Depends on the state of immunity and the severity of the disease.

Usually, with moderate forms against the background of a normally functioning immune system, a periodic increase in temperature can be observed up to 3-4 days.

AT general analysis blood shows signs of a bacterial infection. Leukocytosis appears with a shift of the formula to the left, a significant acceleration of the erythrocyte sedimentation rate, the appearance of C-reactive protein.

To clarify the pathogen, a microbiological examination of a throat swab is carried out with the determination of sensitivity to antimicrobial agents.

1. Purulent:

otitis;
sinusitis;
mastoiditis;
mediastinitis;
meningitis;
endocarditis;
sepsis;
pneumonia.

2. Non-purulent:

glomerulonephritis
toxic shock
rheumatism.

Article prepared by:
Chernenko A.L., infectious disease specialist.

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Review: Antibiotic Alembic "Azithromycin" - How did three tablets cure a sore throat?

Attention! Before using medicines, consult a specialist!

Advantages:
effect, short course

Flaws:
side effects, contraindications

About half a year ago, for no reason at all, I had a high body temperature and terrible pains in the eagle began. At first I thought I had caught a common viral infection at work, but the next day I got even worse. So I decided not to put off going to the doctor any longer, took time off from work and went to the clinic.

The doctor examined me, listened to my complaints and diagnosed me with angina. Naturally, angina is not treated with ordinary throat swabs, which is why the doctor prescribed me a three-day course of treatment with an antibacterial drug called Alembic "Azithromycin", which I want to tell you about today, my dear friends.

This drug is sold in a cardboard box, which contains the medicine itself and detailed instructions for its use. There were only three tablets in the package, which were my course of treatment. Every day I had to take one tablet at the same time and drink it with water.

It is not worth taking such an antibiotic only with food, it is better before a meal or a couple of hours after a meal. So the effectiveness of the drug will be much higher. The dosage for my Azithromycin was 500mg.

After taking the first pill, I felt much better. The temperature dropped, the pain in the throat became less painful. Every day I felt better and better. As a result, for three with the help of this drug, I managed to completely get rid of a sore throat, which I was incredibly happy about.

Of course, like any antibiotic, Azithromycin has side effects and contraindications, but they did not manifest themselves in me. Of course, antibiotics are not better treated, but in some situations they simply cannot be dispensed with.

So, given my positive experience with the antibiotic Alembic "Azithromycin", I can recommend this drug to you, provided that it is prescribed to you by a qualified doctor.

Thank you for your attention to my review.

Year of manufacture/purchase:

General impression. How did three pills cure a sore throat?

Antibiotics for angina in adults and children. List of effective antibiotics for the treatment of angina and how to take

What antibiotics to take for angina

infectious acute illness, manifested by inflammation of the tonsils, requires serious treatment. Antibiotics for angina can only be prescribed by a doctor. As a rule, the appointment depends on the form of the course of the disease and the individual characteristics of the patient. Also, drugs are prescribed based on the type of disease:

lacunar form requires cephalosporins;
with purulent sore throat, drugs of the penicillin group are prescribed;
with catarrhal angina, macrolides are effective;
the follicular type of the disease should be treated with penicillin preparations;
the streptococcal form will require penicillin drugs and cephalosporins.

Flemoxin Solutab with angina

Antibiotic Flemoxin has proven itself in the treatment of acute tonsillitis. The drug is rapidly absorbed from the stomach, so the maximum concentration is reached quickly. If the patient's condition requires emergency treatment, then doctors prescribe Flemoxin for angina. The drug is available in yellow or yellow tablets. white color(dosage 1000, 500, 250, 125 mg.) The course of therapy depends on the severity of the disease. With a moderate or mild degree, you should take the medicine for a whole week, 2 g per day, morning and evening.

Side effects of Flemoxin:

allergic reaction;
diarrhea;
pseudomembranous colitis;
hemolytic anemia;
angioedema.

intolerance to penicillin drugs;
disruption of the liver.

Azithromycin for angina

A drug such as Azithromycin is suitable for the treatment of children and adults. It effectively fights against frequent pathogens of tonsillitis: streptococcus and staphylococcus aureus. The drug is rapidly absorbed from the gastrointestinal tract, penetrates well into skin covering, soft tissues, Airways. Use it only once a day for five days. After the end of the medication, the medicine continues to work for another week.

Side effects Azithromycin for angina:

Augmentin for angina

The drug Augmentin fights a variety of bacterial infections that occur due to the penetration of bacteria into the body. Release form: syrups, tablets, suspensions, composition for injections. For children of twelve years and older, and for adults, tablets are used according to the instructions: 125 mg or 500 mg 3 times a day. It is recommended to use Augmentin from a sore throat for at least seven days, but if the form of the disease is complex, then two weeks.

angioedema;
rash;
constipation or diarrhea;
physical weakness;
bloating,
insomnia;
exhaustion.

chronic kidney disease;
allergy to penicillins;
pregnancy;
jaundice.

Ceftriaxone for angina

In the purulent form of the disease, Ceftriaxone preparations are administered intramuscularly. The antibiotic itself helps fight bacteria that are resistant to substances from the penicillin group. Children under 12 years of age are prescribed 20 or 80 mg per kg of body weight per day. Adults are prescribed 2 g once a day, rarely the doctor breaks the dose into two injections. In one buttock, you can enter no more than one gram of the drug per day. Treatment lasts at least a week.

Ceftriaxone with angina can cause the following side effects:

eosinophilia;
skin rash;
anaphylactic shock;
fever
serum sickness;
dizziness;
nausea;
flatulence;
stomatitis.

Sumamed with angina

The broad-spectrum antibacterial drug Sumamed for angina should be used only under the supervision of an ENT specialist. It is not recommended for use in the treatment of acute respiratory infections, acute respiratory viral infections. Carefully medication you need to drink to children, because the child's body is sensitive to the influence of the components of the drug. The result from the use of the drug will be noticeable at the end of the second day. Drink the drug should be only once a day (500 mg) for 5 days.

Adverse reactions of Sumamed:

Contraindications for use:

diseases of the liver and kidneys;
high sensitivity to the composition of Sumamed;
lactation.

Macropen with angina

The instructions for the drug Macropen noted that it should be taken before meals with clean water. The remedy will begin to act two hours after ingestion. The peculiarity of this drug is that it is effective in angina against microorganisms that are resistant to penicillin. As a rule, Macropen with angina is prescribed for a period of not more than 10 days, but not less than 5. For adults, the dosage per day is 1.6 g (3 doses). Children's angina is treated with a suspension based on the child's body weight. The dose can only be determined by a doctor.

intestinal disorders;
nausea;
heart and kidney failure;
headache;
weakness.

Learn more about the drug amoxicillin - dosage for adults and children, instructions for use and contraindications.

Antibiotic sore throat spray

The choice of drug is often based on the characteristics of the course of the disease and the individual wishes of the patient. A sore throat spray with an antibiotic cannot replace the drug and completely cure the disease. Its main task is only to eliminate or muffle local symptoms: dryness, pain, burning, sore throat. Possessing antifungal and antiseptic components, sprays are able to disinfect the mucous membrane of the tonsils and cope with pathogenic bacteria, mushrooms. The most popular throat sprays are:

How many days to drink antibiotics for angina

Many patients and especially parents of young patients are often interested in the question of how many days to drink antibiotics for angina? The exact period of taking the drug may depend on the form of the disease and the individual characteristics of the patient. Only a doctor can prescribe the amount of medicine. As a rule, antibiotics are taken for 7 to 15 days. An exception is Azithromycin, some of its drugs are used for angina for 3 days, rarely 5 days. If within three days the state of health has improved, you should not stop drinking antibiotics, because complications may arise.

The price of antibiotics for angina

You can buy antibacterial drugs today at any pharmacy. In addition, such medicines can be inexpensively bought and ordered at an online pharmacy. List of the most popular antibiotics:

The child had a fever for 5 days, tried to get by with folk remedies and antipyretic pills. After examination, the doctor diagnosed me with angina. He prescribed us a strong antibiotic for tonsillitis Sumamed. I liked the fact that you have to drink it once a day. Improvement came by the end of the second day. We drank, as expected - 5 days.

I suffer from chronic tonsillitis. There are occasional exacerbations. I drink a course of Tonsilgon N, but it does not always help. With a strong chill and temperature, I begin to drink antibacterial drugs. The best antibiotics for sore throats are Flemoxin and Bioparox spray.

What antibiotic is taken for angina 3 tablets?

The antibiotic azithromycin is used in 3 tablets for angina, and therefore all preparations based on it: Azitrox, Sumamed, Azimed, Hemomycin, Azivok and others.

It is somewhat naive to believe that if azithromycin is used for only three days, one tablet a day, then it is safer and easier to tolerate. In fact, it causes no less side effects than other macrolides, and it also often leads to digestive disorders. However, in some cases, this drug does turn out to be more preferable than other known antibiotics for sore throats.

When is azithromycin prescribed for angina

Despite the convenient scheme of application, azithromycin has its drawbacks - for example, its effect on the gastrointestinal tract

Even in situations where the sore throat pathogen is resistant to pure penicillins, doctors prefer not to prescribe azithromycin, but protected amoxicillin or ampicillin in the form of Augmentin, Amoxiclav or Sultamicillin. At the same time, there is no particular difference between the safety of these drugs and macrolides.

The price of 3 tablets of azithromycin is approximately 190 rubles.

Rules for the use of azithromycin

Possible schemes for taking azithromycin (the second - for 5 days - is preferable and more effective)

Side effects and safety of use

Today, statistics on the incidence of various side effects when using azithromycin are collected and well known:

Diarrhea - in 5% of cases (especially often with a three-tablet scheme);
Pain in the abdomen - in 3% of cases;
Nausea - in 3% of cases;
Flatulence, vomiting - in 1% of cases;
In children, constipation, gastritis - in 1% of cases;
Fungal lesions of the oral cavity (including fungal tonsillitis) - in 1%; cases;

Oral and throat candidiasis is a common side effect of heavy antibiotic use.

Inflammation of the kidneys - in 1% of cases; Chest pain - in 1% of cases; Dizziness, headache, drowsiness - in 1% of cases; In children, sleep disturbances, neuroses - in 1% of cases; Allergic reactions - in 1% of cases.

Depending on the severity of these side effects, the doctor may prescribe additional drugs to eliminate them, or change the antibiotic. It is likely that when taking the same Vilprafen, no side effects will appear, although the remedy itself is intended to be taken for at least 10 days.

When treating a nursing mother with azithromycin, breastfeeding may have to be stopped for a while

Three tablets per course for angina, only the antibiotic azithromycin is used;
If possible, it is desirable to replace azithromycin with penicillin preparations;
If possible, three tablets of the remedy are taken for 5 days, not three. In this case, the effectiveness of treatment increases.

With the advent of antibiotics of the “macrolides and azolides” group in medical practice, the treatment of many infectious diseases has become much simpler and fits into the intake of only 3 tablets in three days.

Antibiotics in tablets, the course of treatment of which is limited to only three doses, contain azithromycin.

Azithromycin belongs to the subgroup of azalides from the macrolides and azalides group. Azolides are low toxic and have a wide spectrum of antimicrobial activity.

The most common azalide antibiotic is the antimicrobial drug azithromycin.

Action of azithromycin:

in high concentration - bactericidal, the drug kills bacteria;
in small concentrations - bacteriostatic, i.e., inhibiting the growth of pathogens.

The ability of an antibiotic to cure an infection in three days is explained by its ability to accumulate in bactericidal concentration in the focus of inflammation in 1-3 hours and remain at a high level after taking the medicine.

Antibiotics that are drunk for only 3 days in the treatment of a bacterial infection include drugs with trade names:

Sumamed;
Hemomycin;
Zitrolide;
Azivok;
Azitrus forte;
Azitral;
Z-factor;
Sumamox;
Ecomed;
Azithromycin Zentiva.

Most often, antibiotics with the trade names Sumamed, Hemomycin, Azithromycin are prescribed, which are sold in an economical package of 3 tablets, which is enough for a course of treatment lasting three days.

Azithromycin is characterized by:

long half-life;
the ability to accumulate in the lesion in a higher concentration than in blood plasma;
post-antibiotic action.

Post-antibiotic effect

The phenomenon of the post-antibiotic effect is that after the antibiotic is discontinued, the ability of bacteria to reproduce is not restored, but remains reduced.

The post-antibiotic effect is observed in many antibiotics, but most often it is only a few hours.

In azithromycin, the duration of the post-antibiotic action reaches 5-7 days.

This means that even a week after the pills are discontinued, the medicine continues to act and effectively destroy the pathogenic microflora.

The drug is not exposed to the action of gastric juice and is well absorbed in the stomach. Azithromycin does not cause severe side effects. And a short course of antibiotic treatment, limited to 3 tablets, further reduces the risk of an undesirable effect of the drug.

Due to these properties, one tablet per day can be used in the treatment of antibiotics with the names Sumamed, Azitorx, Hemomycin for the treatment of infections, limited to 3 doses during the entire time of illness.

Indications

Drugs accumulate in high concentrations in the tissues of the palatine tonsils, adenoids, bronchi, penetrate into the prostate, other organs of the genitourinary system, human skin. Due to this, macrolides and azalides are used in the treatment of:

ENT - organs - tonsillitis, sinusitis, pharyngitis, laryngitis, otitis media, chronic tonsillitis;
respiratory diseases - tracheitis, bronchitis, pneumonia;
genitourinary system - prostatitis, inflammation of the cervix, chlamydial urethritis, cervicitis;
the initial stage of borreliosis;
scarlet fever;
skin infections - erysipelas, impetigo, dermatitis;
diseases of the stomach associated with the presence of Helicobacter pylori bacteria.

Medicines containing azithromycin are used in the treatment of diseases of the digestive system that are caused by the bacterium Helicobacter pylori. An antibiotic in tablets is prescribed for a course of 3 days in combination with other means of complex therapy.

Read about the use of macrolides and antibiotics of other groups for bacterial infections of the respiratory tract and colds on the page.

The spectrum of action of azithromycin

Azithromycin, like other macrolides, is used in the treatment of infections as second-line drugs for allergies to beta-lactam antibiotics, which include penicillins, cephalosporins.

Rules for taking azithromycin

Azithromycin is taken 1 r./day. If the tablet is missed, then it is taken on the same day at any other time. The next tablet is drunk exactly 24 hours later.

The drug is washed down with clean water. Neither juice, nor coffee or alcohol can be washed down with an antibiotic.

The medicine is drunk between meals on an empty stomach. After eating, at least 2 hours must pass for the drug to be completely absorbed.

Schemes for the use of antimicrobial agents in diseases of different organs differ. Azitormycin is taken once at a dosage of 1000 mg in the treatment of chlamydial infections with urethritis and cervicitis.

For the treatment of adults from bacterial infections of the respiratory tract, complications of the common cold, three 500 mg antibiotic tablets will be required.

Children are prescribed a dosage depending on weight. When treating children under 12 years of age or weighing less than 45 kg, it is more convenient to use granules for the preparation of a suspension.

Otherwise, the treatment regimen for pharyngitis, sinusitis, tonsillitis, laryngitis, bronchitis in children is the same:

reception once a day;
after eating after 2 hours or one hour before meals.

Azithromycin in the treatment of stomach

Antibiotic tablets are taken for 3 days in the treatment of stomach diseases caused by the bacterium Helicobacter pylori. For adults, the dosage is 1000 mg at a time.

Azithromycin, when used against Helicobacter pylori, is prescribed in combination with other drugs; it is not used as monotherapy.

Like any other antibiotics, drugs containing azithromycin can provoke a violation of the composition of the normal intestinal microflora.

And about ways to restore microflora after a course of treatment - on the page.

Azithromycin contraindications

Like any medicine, azithromycin has contraindications. A dangerous feature of azithromycin is the possibility of its negative effect on the electrochemical conduction of the cardiac impulse.

Taking azithromycin for even a short course can lengthen Q-T interval on the electrocardiogram, resulting in arrhythmia.

Other contraindications include:

children's age up to six months;
kidney failure;
liver disease;
lactation period.

In infections of the respiratory system, ENT diseases during pregnancy, preference is given to safer beta-lactam antibiotics of the penicillin or cephalosporin series in terms of side effects.

However, in case of allergy to penicillins, the doctor may prescribe an antibiotic from the group of macrolides and azalides if the expected benefit to the mother is higher than the possible harm to the fetus.

Side effects of azithromycin

Side effects occur in 1% of cases and are manifested:

flatulence;
violation of the stool - diarrhea, constipation;
cholestatic jaundice;
dizziness;
chest pain;
tachycardia;
headache;
allergies - urticaria, conjunctivitis, pruritus.

Although no dose adjustment is required in the treatment of the elderly and normal adult dosages are used, the risk of ventricular cardiac arrhythmia must be considered.

The appearance of unpleasant symptoms is possible with an overdose of the antibiotic. If nausea, vomiting, hearing loss, stool disorders occur, the medication should be stopped immediately and consult a doctor.

Sumamed

The antibiotic in tablets and capsules called Sumamed contains azithromycin and is used in a short course, consisting of three doses for 3 to 5 days. The drug is sold as:

dispersible tablets with a dosage of 1000, 500, 250, 125 mg;
capsules of 250 mg and film-coated tablets containing 125 and 500 mg of azithromycin.

Be sure to pay attention to what dosage is indicated on the package with the name of the drug. Although the antibiotic has low toxicity, there is a risk of overdose, especially for children and the elderly.

The drug is widely used in the treatment of respiratory organs, it is effective against bacterial complications caused by SARS.

Directly against influenza and SARS, the drug is useless, but when a cold is prolonged and complicated by bronchopneumonia, tonsillitis, purulent sinusitis, the doctor may prescribe Sumamed.

For the treatment of bacterial complications of the common cold, one pack of 3 tablets of this strong antibiotic is enough to suppress the infection in the bronchi, throat, and sinuses.

One tablet of the drug is prescribed to children daily for 3 days in a row for infections of the respiratory system. The dosage is calculated by body weight:

from 18 kg to 31 - 250 mg each;
from 31 kg to 45 kg - 375 mg;
more than 45 kg, as for adults - 500 mg.

For children under 3 years of age, Sumamed is prescribed in the form of a powder for the preparation of solutions. Proceed from the proportion of 20 mg per kg of weight.

Hemomycin

Hemomycin 500 film-coated tablets are packaged in packs of 3, dispensed by prescription. The name of the active substance and the dosage of azithromycin are indicated on the package.

Hemomycin, like other azithromycins, is used in stepwise therapy for pneumonia. Scheme for the treatment of pneumonia:

the first two days - intravenous administration of a solution for infusion at a dosage of 500 mg;
a single daily dose of medication for 7 to 10 days.

The solution should be administered drip for an hour or more. Treatment should only be carried out in a hospital, since when using Hemomycin, complications from the heart and blood vessels are possible.

Treatment of bacterial diseases of the upper respiratory tract and complications of a cold lasts 3 days, and for a complete recovery, it is enough to take 3 tablets at a dosage of 500 mg for adults, and for children at a dose prescribed by a doctor.

Z-factor

The domestic drug Zi-factor is available in 250 mg capsules and 500 mg tablets of azithromycin. Like other antimicrobials containing azithromycin, Zi-factor is prescribed for bacterial diseases of the respiratory system, urogenital infections, and skin diseases.

Good Z-factor helps with angina and sinusitis. Sore throat caused by angina is eliminated in a day. Quickly passes headache, nasal congestion with sinusitis.

The advantages of azithromycin include its inexpensive cost in comparison with other antibacterial agents. Domestic drugs containing azithromycin are no less effective than the patented drug Sumamed, and cost almost 3 times less.

Antibiotic drugs are used to treat bacterial infections. Antibiotics are an effective therapy for the most common forms of diseases such as:

All listed ailments must be treated immediately and only with antibiotics in order to avoid serious complications and further spread of infection.

Lack of adequate and timely antibiotic therapy can lead to:

Some of these conditions are only treated with surgery followed by long-term drug therapy. All these complications often cause the development of chronic pathological processes, or conditions that can threaten the life of the patient.

Important! The selection of an antibiotic drug, the appointment of a dosage and a course of therapy is carried out exclusively by a doctor! Independent and uncontrolled antibiotic treatment is not allowed!

Benefits of a three-day course of antibiotic therapy

Due to the powerful effect of the substance, the course of treatment with this drug is limited to three tablets. Full recovery occurs a few days after the end of the course of treatment.

The principle of action of this drug lies in its ability to block the function of protein synthesis by pathogenic microorganisms, leading to their destruction.

Azithromycin has good resistance to the effects of gastric juice and is completely absorbed into the gastrointestinal tract. A long period of elimination of azithromycin from the body ensures the preservation of therapeutic properties for a week after the end of the course. A low percentage of possible side effects allows the appointment of medication even for children.

As noted above, the antibiotic azithromycin provides complete recovery after taking only three tablets, one package containing three 500 mg tablets is designed for three days of intake by an adult. In some cases, taking three tablets is more appropriate to divide into five days. In this case, the drug is taken according to the scheme:

the first day - one tablet;

the second and subsequent days, half a tablet.

For the treatment of children, the dosage of the drug is calculated taking into account the weight of the baby, at the rate of 10 mg per kilogram of weight on the first day of treatment, and in the next four days the dose of the drug is reduced by 5 mg.

The use of the antibiotic azithromycin requires increased attention and caution in such cases:

At the age of six months to twelve years (with a child weighing less than 45 kg), it is not recommended to take the drug in the form of tablets and capsules; at the age of sixteen years, intravenous administration of the drug is not recommended.

During pregnancy and during the period of breastfeeding, the medication is allowed to be taken if the effect of the drug on the health of the mother exceeds the threat to the health and life of the fetus.

Antibiotic drugs based on azithromycin

Sumamed is an antibiotic based on azithromycin, which is also available in three tablets per pack.

Indicated for use with:

Infectious diseases of the upper and lower respiratory tract.

Skin infections.

STD.

The course of taking this remedy is also designed for three or five days, depending on the disease. For infectious diseases of the respiratory system, a course is prescribed for three days, one tablet per day, and for the chronic stage of erythema, the course of therapy is five days, according to the scheme: the first day is two tablets, the next - one.

The use of Sumamed for the treatment of acute stages of urogenital infections is limited to a single dose of a double dose (two 500 mg tablets once).

Important! If the patient misses a dose of the drug, then it is necessary to take the missed dose of antibiotic as soon as possible, and take subsequent tablets no earlier than 24 hours later.

Contraindications to taking this drug are the same as those of Azithromycin.

Also, based on azithromycin, drugs are produced with the following names:

All these drugs have different forms of release, with different dosages of the active ingredient. These can be tablets, 125 mg, six pieces per pack, or 500 mg, 3 pieces per pack. Also available in capsule, powder or syrup form. The recommended daily dose for an adult is 500 mg.

Side effects and risk of overdose

The drug is taken orally one hour before a meal or two hours after a meal.

Rare side effects of drugs include:

Simultaneous intake of these antibiotics with food or ethanol can lead to a slowdown and decrease in absorption. With simultaneous therapy with azithromycin and drugs that reduce the acidity of the stomach, it is necessary to observe a break between doses of at least two hours.

In the case of uncontrolled intake of antibiotic drugs, an overdose may occur, a symptom of which is nausea, sometimes turning into vomiting, diarrhea, and hearing may be temporarily lost.

Treatment of an overdose should begin immediately with gastric lavage and further symptomatic therapy.

Azithromycin preparations are removed in two stages:

Elimination half-life within 14 - 20 hours, 8 - 24 hours after taking the drug.

Complete elimination within 41 hours, 24 - 72 hours after taking the drug.

The long period of elimination of the drug is due to its use once a day. In the focus of the inflammatory process, the antibiotic persists up to 7 days after the last dose taken, which determines the effectiveness of a short course of therapeutic therapy.

The appointment of this antibiotic and its required dosage is made only by a specialist, with a mandatory preliminary determination of the sensitivity of the microflora that caused the disease in the patient to the prescribed drug.

APPROVED

By order of the chairman

Medical and
pharmaceutical activities
Ministry of Health
Republic of Kazakhstan

From "______" __________ 201___

Instructions for medical use

medicinal product

Sumamed®

Tradename

Sumamed®

International non-proprietary name

Azithromycin

Dosage form

Film-coated tablets, 500 mg

Compound

One tablet contains

active substance- azithromycin dihydrate, 500 mg

Excipients: calcium hydrogen phosphate anhydrous, hypromellose 15 mPa.s, corn starch, pregelatinized starch, microcrystalline cellulose, sodium lauryl sulfate, magnesium stearate

Shell composition: hypromellose 15 mPa.s, titanium dioxide (E171), indigo carmine (E 132), polysorbate 80, talc, purified water.

Description

Light blue film-coated tablets, oblong, biconvex, marked "PLIVA" on one side and "500" and "500" on the other side.

Pharmacotherapeutic group

Antimicrobials for systemic use. Macrolides, lincosamides and streptogramins. Macrolides. Azithromycin.

ATX code J01FA10

Pharmacological properties

Pharmacokinetics

Azithromycin is rapidly absorbed when taken orally, due to its stability in an acidic environment and lipophilicity. After a single oral dose, 37% of azithromycin is absorbed, and the peak plasma concentration (0.41 µg / ml) is recorded after 2-3 hours. Vd is approximately 31 l/kg. Azithromycin penetrates well into the respiratory tract, organs and tissues of the urogenital tract, the prostate gland, into the skin and soft tissues, reaching from 1 to 9 µg / ml, depending on the type of tissue. The high tissue concentration (50 times higher than the plasma concentration) and long half-life are due to the low binding of azithromycin to plasma proteins, as well as its ability to penetrate eukaryotic cells and concentrate in the low pH environment surrounding lysosomes. The ability of azithromycin to accumulate in lysosomes is especially important for the elimination of intracellular pathogens. Phagocytes deliver azithromycin to the sites of infection, where it is released during phagocytosis. But despite the high concentration in phagocytes, azithromycin does not affect their function. Therapeutic concentration remains 5-7 days after ingestion of the last dose. When taking azithromycin, a transient increase in the activity of liver enzymes is possible. Removal of half the dose from plasma is reflected in a decrease in half the dose in tissues within 2-4 days. After taking the drug in the range from 8 to 24 hours, the half-life is 14-20 hours, and after taking the drug in the range from 24 to 72 hours - 41 hours, which allows you to take Sumamed 1 time per day. The main route of excretion is with bile. Approximately 50% is excreted unchanged, the other 50% is in the form of 10 inactive metabolites. Approximately 6% of the dose taken is excreted by the kidneys.

Pharmacodynamics

Azithromycin is a broad-spectrum antibiotic, the first representative of a new subgroup of macrolide antibiotics - azalides. It has a bacteriostatic effect, but when high concentrations are created in the focus of inflammation, it causes a bactericidal effect. By binding the 50S ribosomal subunit, azithromycin inhibits protein synthesis in sensitive microorganisms, showing activity against most strains of gram-positive, gram-negative, anaerobic, intracellular and other microorganisms.

MIC90 ≤ 0.01 µg/mL

Mycoplasma pneumoniae Haemophilus ducreyi

MIC90 0.01 - 0.1 µg/ml

Moraxella catarrhalis Propionibacterium acnes

Gardnerella vaginalis Actinomyces species

Bordetella pertussisBorrelia burgdorferi

Mobiluncus species

MIC900.1 - 2.0 µg/ml

Haemophilus influenzaeStreptococcus pyogenes

Haemophilus parainfluenzaeStreptococcus pneumoniae

Legionella pneumophilaStreptococcus agalactiae

Neisseria meningitidis Streptococcus viridans

Neisseria gonorrhoeaeStreptococcus group C, F, G

Helicobacter pyloriPeptococcus species

Campylobacter jejuni Peptostreptococcus

Pasteurella multocida Fusobacterium necrophorum

Pasteurella haemolytica Clostridium perfringens

Brucella melitensis Bacteroides bivius

Bordetella parapertussisChlamydia trachomatis

Vibrio choleraeChlamydia pneumoniae

Vibrio parahaemolyticus Ureaplasma urealyticum

Plesiomonas shigelloides Listeria monocytogenes

Staphylococcus epidermidis

Staphylococcus aureus*

(*erythromycin - sensitive strain)

MIC902.0 - 8.0 µg/ml

Escherichia coliBacteroides fragilis

Salmonella enteritidisBacteroides oralis

Salmonella typhiClostridium difficile

Shigella sonnei Eubacterium lentum

Yersinia enterocolitica Fusobacterium nucleatum

Acinetobacter calcoaceticus Aeromonas hydrophilia

Indications for use

Pharyngitis / tonsillitis, sinusitis, otitis media

Bronchitis, interstitial and alveolar pneumonia, exacerbation of chronic bronchitis

Chronic erythema migrans - the initial stage of Lyme disease, erysipelas, impetigo, secondary pyodermatoses

Diseases of the stomach and duodenum associated with Helicobacter pylori

Gonorrheal and non-gonorrheal urethritis and/or cervicitis

Dosage and administration

Sumamed® tablets 500 mg are taken once a day 1 hour before meals or 2 hours after meals.

With uncomplicated urethritis and / or cervicitis, a single dose of 1 g (2 tablets of 500 mg) is prescribed.

In diseases of the stomach and duodenum associated with Helicobacter pylori, Sumamed® is prescribed 1 g (2 tablets of 500 mg) per day for 3 days as part of combination therapy.

For the treatment of acne vulgaris, the following scheme is used:

500 mg daily as a single dose for 3 days, then 500 mg once a week for 9 weeks, with the dose of the second week to be taken 7 days after taking the first tablet. The next 8 doses are taken 7 days apart. The total dose is 6 g.

In case of missing one dose of the drug, the missed dose should be taken as soon as possible, and subsequent doses should be taken at intervals of 24 hours.

In the elderly and in patients with impaired renal function, there is no need to change the dosage.

Side effects

Often (>1/100,< 1/10)

Nausea, vomiting, diarrhea, abdominal pain

Not often(>1/1000,< 1/100)

Loose stools, flatulence, indigestion, loss of appetite

Rare(>1/1000,< 1/100)

Headache, dizziness, drowsiness, convulsions, dysgeusia

Thromocytopenia

Aggression, agitation, restlessness, nervousness, insomnia

Paresthesia and asthenia

Hearing loss, deafness and tinnitus

Tachycardia, arrhythmia with ventricular tachycardia, prolongation of the QT interval

Tongue discoloration, constipation, pseudomembranous colitis

Transient rise in the level of liver aminotransferases, bilirubin,

cholestatic jaundice, hepatitis

Hypersensitivity reactions (redness, skin rash, itching, urticaria,

angioedema, photosensitivity), erythema multiforme,

Steven-Johnson syndrome and toxic epidermal necrolysis,

Arthralgia

Very rare (>1/10000,< 1/1000)

Interstitial nephritis, acute renal failure

Fatigue, convulsions

Change in taste and smell

Arthralgia

Vaginitis, candidiasis, superinfections

Anaphylactic shock including edema (rarely resulting in death)

Contraindications

Known hypersensitivity to macrolide antibiotics

Severe violations liver and kidney function

Childhood up to 18 years (due to the presence of dye indigo carmine E 132)

First trimester of pregnancy and lactation

Drug Interactions

Antacids significantly reduce the absorption of Sumamed®, so the drug should be taken one hour before or two hours after taking these drugs. Macrolide antibiotics interact with cyclosporine, astemizole, triazolam, midazolam or alfentanil. Careful monitoring is recommended while taking these drugs.

Azithromycin does not affect cytochrome P-450 and therefore does not interact with theophylline, terfenadine, carbamazepine, methylprednisolone, didanosine and cimetidine.

With the simultaneous use of azithromycin and indirect anticoagulants, bleeding is possible. Therefore, it is necessary to control prothrombin time.

With the combination of azithromycin and digoxin, an increase in the concentration of digoxin in the blood is possible, therefore it is necessary to control the level of digoxin in the blood and adjust its dose.