When the result is visible after cortexin. The use of Cortexin for the treatment of children - indications, instructions, reviews

One of the biggest achievements of domestic medicine is the appearance of the drug "Cortexin", which contributes to the treatment of various pathologies that occur in the brain of the human head. It took almost 30 years to develop the drug. The creation and testing of the drug was carried out by the Military Medical Academy.

Did one deserve positive feedback"Cortexin"? Practicing clinicians and leading pharmacologists have proven that this medicine is a leading drug in the field of therapy of the brain and most of the concomitant ailments that have a neural etiology.

Principle of therapeutic effect

What is Cortexin, and what is its therapeutic effect? The drug is a complex morphological structure with many elements. It consists of the simplest protein components, which are balanced in a certain way from vitamins and other biologically necessary compounds. In combination, all these components of the drug "Cortexin" make it possible nerve cells quickly regain lost functions.

Long-term practice confirms the inefficiency of the majority quite strongly. active drugs in the case of therapy for abnormalities in the functioning of the brain of the head. They do not cope with problems due to the inability to overcome this. This is a powerful body defense system that prevents various adverse and aggressive factors from affecting the brain.

Despite the fact that the drug "Cortexin" has a complex structure, it has a rather low level. This allows the drug to quite easily overcome the described barrier and penetrate precisely into the brain, as a result of which therapeutic effect is faster and stronger.

The mechanism of action of the drug

The action of the drug "Cortexin" lies in its ability to restore the disturbed balance between amino acids. They influence activity. important processes biological nature in the nervous system, memory, intellectual abilities, and also suppress reactions in the form of convulsions, prevent the destruction of neurocytes. This effect of "Cortexin" allows you to use it not only in the field of neurology, but also in the case of mental disorders, in neurogyrgy and other therapeutic actions. This versatility of the drug can only cause positive feedback. "Cortexin", in addition to a wide spectrum of action, has one more advantage.

The dose load of the drug on the body is minimal, which contributes to its use, regardless of the age category of patients. Therapy with it can be prescribed to both newborns and people in old age.

Areas of influence of the drug

The positive effect of Cortexin can also be observed in the case Already a few days after the start of taking the drug, the condition of the affected area of ​​\u200b\u200bthe brain and the bed of blood vessels improves, the process of restoring neuropsychic connections that have been broken is accelerated, and positive dynamics is observed when conducting an electroencephalogram. In this case, the drug "Cortexin" also acts indirectly, stimulating an increase in blood flow and improving its access to the affected areas of the brain.

The effectiveness of the drug has also been proven in the treatment of symptoms of various neuroinfectious diseases. With it, it is possible to reduce the number of patients suffering from headaches, weakness and dizziness several times over. This fact also causes more than one positive feedback.

"Cortexin" is also used for ophthalmic abnormalities - with damage to the retina or other departments optic nerve.

Other areas of influence of the drug

The drug exhibits a rapid rehabilitative effect, which provides a positive effect in the treatment of not only the brain of the head, but also areas nervous system, remote from it. For example, Cortexin reduces inflammatory reactions in the case of sacral or lumbar sciatica.

Indications for use

The drug "Cortexin" is used for complex treatment the following conditions and diseases:

• traumatic brain injury;
• bacterial and viral neuroinfections;
• asthenia;
• encephalopathy;
• encephalitis;
• and memory;
• children's cerebral palsy(its different forms);
• reduced ability to learn;
• delayed speech and psychomotor development at an early age;
• radiculitis;
• pathologies of the retina and some others.

Contraindications and side effects of the drug

In some cases, when using Cortexin, allergic reactions occur. Slight redness may appear at the injection site. But pretty soon it disappears, as evidenced by more than one review. "Cortexin" is contraindicated for use in
period of pregnancy and lactation. With individual intolerance to the drug, it is also not recommended for use.

Mode of application

For whatever purpose the drug "Cortexin" is used, its effectiveness depends directly on the stage of the disease, during which treatment was started with it.

The method of introducing the drug into the body is intramuscular injections. The contents of the vials are dissolved either with sodium chloride. The drug is administered daily, once a day. The appropriate dosage for each patient should be prescribed by the doctor.

The recommended amount of Cortexin for newborns and babies weighing less than 20 kg is 0.5 mg per kilogram of the child's weight. The rest is administered 10 mg of the drug daily. The course of treatment is 10 days. It is repeated if necessary. In this case, the break between courses should be at least one month.

Interaction with other drugs

Means "Cortexin" must not be used simultaneously with medicines peptide origin. In the process of its dissolution, Novocain should not be used.

The drug "Cortexin": price

The minimum cost of this drug is 67 rubles per vial (5 mg). At the same time, the lowest price for a package, which includes 10 such bubbles, is 620 rubles. How much does the drug "Cortexin-10" cost? The price of this drug ranges from 100 rubles per bottle to about 1090 rubles per package (meaning 10 vials of 10 mg each).

Cortexin has an antioxidant effect, improves brain function, memory, concentration. Why Cortexin is prescribed, the annotation to the drug will answer, but in any case, the appointment this tool the doctor is engaged and only after the decision of the final diagnosis. The advantage of the drug is the possibility of its use in children, as well as good tolerance.

Cortexin is a drug from the group of nootropics, which is widely used in neurology for the treatment a large number diseases. The use of the drug improves brain activity, stimulates natural processes in his tissues.

Properties

The pronounced nootropic effect of the drug allows it to be used as a cerebroprotective, anticonvulsant and antioxidant agent in the treatment of many CNS pathologies. The drug allows you to protect neurons from damage, as well as toxic effects, prevents the development of hypoxia of brain tissues, improves and stimulates blood circulation.

Advice! Before using the drug, you need to know what Cortexin helps with, what effect it has on the body, how to inject Cortexin and other useful information.

The active components of Cortexin have the ability to penetrate into the brain tissue, where they have positive influence for recovery processes. Cortexin, one of the safe stimulant drugs that can reduce the negative effects of psychotropic drugs.

Application this medicine eliminates toxic effects, improves memory, performance. Cortexin has the ability to restore natural processes in the body, and also protects neurons and brain vessels from the adverse effects of the internal and external environment.

The drug takes part in stimulating the synthesis of substances that affect the patient's psycho-emotional state (serotonin and dopamine), regenerative processes in brain tissues, and also increases stress resistance, normalizes the work of the whole organism.

The drug may be prescribed in the following cases:

1. Nervous tension, stress.
2. encephalopathy.
3. Violations of blood flow in the vessels of the brain.
4. Consequences of neuroinfection.
5. Decreased performance and mental stress.
6. Decreased and impaired memory.
7. Chronic fatigue.
8. Unstable mood.
9. Sleep disturbance.
10. Delayed psychomotor development.
11. Vegetative disorders.

Cortexin injections can be prescribed in combination with other drugs for rehabilitation after a stroke, pathologies of the heart muscle, and disorders in the brain. The medicine is used to improve the condition of the optic nerve, with radiculitis.

Before injecting Cortexin, it must be diluted with 9% sodium chloride or water for injection. It is allowed to dilute the drug with a solution of novocaine. Enter the medicine 1 time per day. According to indications, adults are administered 10 mg of the drug per day.

When prescribing Cortexin to children under 20 kg, the daily dose is 5 mg. If necessary, the doctor can extend the course of taking the drug or repeat it after 6 months.

Method of application Cortexin - intramuscular, while injection manipulation should be carried out medical specialist. It is necessary to dilute the ampoule of the drug immediately before its administration.

Like any other drug, Cortexin has its own contraindications, including:

1. Hypersensitivity to the composition of the drug.
2. Pregnancy.
3. lactation period.

Unlike other drugs, Cortexin's contraindications are minimal, which makes it possible to prescribe it to both children and the elderly with a history of chronic diseases.

As the instructions for the drug indicate, Cortexin is not recommended for use in combination with peptide drugs, and doctors also do not recommend using novocaine as a solution.

Side effects of Cortexin are quite rare. In some cases, with individual intolerance to the active substance, allergic reactions may occur, in the form of a skin rash, itching, redness of the skin in the area of ​​the injection.

An overdose of the drug has not been registered. Despite the safety of the drug, how to take Cortexin, the duration of the course of treatment with this drug should be prescribed by a doctor and only after the final diagnosis. The effectiveness of the drug depends on the stage of pathology, concomitant diseases, the age of the patient.

golmozg.ru

Means Cortexin restores brain activity

Cortexin is presented as a polypeptide drug with a unique and balanced composition of neurotransmitters. They have a tissue-specific effect on the cerebral cortex. The agent significantly affects the reduction of the toxic effects of various substances, directly on the subcortex of the entire brain area.

Pharmacology Cortexin

A polypeptide preparation with a fairly optimal and well-calculated composition of substances necessary for life has a tissue-specific effect on the cerebral cortex. It reduces the level of toxic effects of various substances, while increasing cognitive performance and improving the learning ability of each patient.

In addition to all of the above, the drug is able to significantly enhance the work of processes in the central nervous system. The agent affects with the help of anticonvulsant or cerebroprotective action.

The medicine helps to recover much faster the work of the central nervous system, which has undergone severe stress.

Cortexin can actively normalize the ratio different types amino acids to each other throughout the brain space, actively regulates the concentration of substances such as dopamine and serotonin. The drug is able to provide great assistance in restoring the previous work of brain cells.

All pharmacokinetic data cannot be accurately determined, because L-amino acids with neuropeptides that are part of the drug Cortexin can completely disintegrate in just 3 minutes. This makes it impossible to know the exact data on absorption, the process of discretion, and the gradual distribution of peptide residues.

pharmachologic effect

A drug that contributes to a significant improvement in brain metabolism has a positive effect on the human body. Cortexin can be called a common lyophilisate, which was obtained as a result of acetic acid extraction taken from pigs from their cerebral cortex. The substance is rich in that it contains active substances - neuropeptides, their specific molecular weight can be about 10,000 daltons, which is enough to penetrate the BBB.

Cortexin can also have a tissue-specific effect on brain cells, this is evident from the process of metabolic regulation, the process of neuroprotection. The drug is able to influence the increase in the efficiency of the process of metabolism of brain tissues, contributes to the regulation of intracellular protein synthesis.

It can regulate the origin of the lipid peroxidation reaction in the brain, block unwanted oxidation, reduce the possibility of radicals. The drug can eliminate the imbalance of all amino acids in the body, has a moderate GABA-ergic effect.

It is able to have some effect on the violation of body functions, normalizes concentration, improves the ability to improve the learning process, helps restore memory, restores working functions during stress. Provides a stimulating effect for mental activity, and also increases activity. The drug is able to normalize the ongoing work of the entire brain.

Nootropic drug

It contains a full complex of various low molecular weight compounds, which make up a mass of about 10,000 daltons, occurring in the cerebral cortex of the head in animals. Passes directly along the BBB directly to the nerves. Tablets are able to have an antioxidant, nootropic, neuroprotective and tissue-specific effect in the body.

Nootropic action

It makes the work of the entire part of the brain more efficient, improves a person’s memory, increases attention in various situations, and provides stability as a result of severe stress.

Neuroprotective action

Provides reliable protection for neurons from the undesirable influence of endogenous factors on them, reduces the final effect of the influence of substances on the psyche.

Antioxidant effect

It can inhibit the process of lipid peroxide oxidation, increase the number of surviving neurons when creating oxidative stress.

Tissue-specific effect

It helps to activate the metabolism of neurons in the human nervous system, ensures the occurrence of reparative processes, can much more effectively increase the work of the cerebral cortex and increase the tone of the entire system of nerves.

See also: To whom and when is Tempalgin indicated

Mechanism of action

The effectiveness of Cortexin is ensured by the high activation of peptides of numerous factors that affect the functioning of the brain. This is also influenced by the optimization of the metabolic process. different types amino acids, substances of serotonin, dopamine. A significant decrease in paroxysmal brain function also affects, it significantly improves high bioelectrical activation, and prevents possible formation of radicals.

Application features

Like any drug, pharmacological agent Cortexin is indicated for use in certain cases. Among these situations are the following:

Contraindications for admission

• Pregnancy (in women);
• Intolerance to the constituent components of the drug on an individual basis for each patient.

Doses of application

The drug in question must be administered exclusively intramuscular way. A full bottle before injection should be dissolved in a 0.5% solution of procaine, a 0.9% solution of sodium chloride substance or in special water for injection.

It is necessary to direct the needle better to the very wall of the vial, this will help prevent possible foaming. It is important to administer the drug every day once: adults need 10 mg, the course is 10 days; children weighing less than 20 kg at 0.5 mg / kg, if the child weighs more than 20 kg, then you need to enter 10 mg, the course is 10 days.

If the expected effect was not achieved, you can conduct another repeated course, after 3-6 months. When the patient has had a hemispheric ischemic stroke, then give adults 10 mg twice a day for 10 days. Two weeks later, you can conduct another course.

Side effects

So far, there has been no information about the occurrence of side effects. Some patients may develop individual intolerance to any of the components.

Before taking Cortexin, it is better to consult with an experienced specialist doctor. He will advise the appropriate drug and prescribe the optimal doses for taking.

Storage methods

The drug is best stored in a completely dry and completely dark place at a temperature of 2 ° - 20 ° C. It is better to put it on the upper shelves, which are not accessible to children, in order to avoid unpleasant situations.

Mode of application

It is recommended to use the drug intramuscularly. The entire contents of a full vial for use must be dissolved before administration in an appropriate vehicle. As a solvent, plain water for injection can be used for these purposes.

It should be administered once a day, with adults requiring 10 mg, and the course is 5-10 days. In the department of pediatrics: babies weighing more than 20 kg are supposed to adult dosage, and those who have less weight can take 5 mg once a day. The full course of treatment is 5-10 days. If necessary, such a course can be repeated.

Features of the use of Cortexin

It is necessary to take the remedy after consulting a specialist who can accurately indicate the dose for admission and set the duration of the course according to the characteristics of your body. At medical appointment Cortexin does not affect the control of various mechanisms and cars.

The use of the drug also does not have any effect on the performance of serious and dangerous work, where a quick reaction and increased attention are needed (management of dangerous mechanisms, control vehicle and so on).

Additional instructions

Cortexin should be used strictly after consultation with a specialist, setting the duration and dosage. The finished solution is not recommended for use after the expiration date. Do not mix the finished solution of the drug with other means. If you use injections in accordance with all the rules and recommendations, the effect of it can be observed after just a few doses.

See also: Painkiller Pentalgin N

If you miss a scheduled injection, you do not need to increase the next dose of the drug. You need to carry out the next reception without any changes. Certain precautions for the disposal of a spoiled drug are not required.

If your job is related to driving a car, you should not worry. The drug has no effect on the performance of responsible and dangerous work. It has no effect on reducing reaction and attention.

The use of the drug in children

It is necessary to use Cortexin for children in accordance with the prescribed dosages of the doctor. Doses to take may vary depending on the weight and age of the child, so be careful.

Precautionary measures

• Use the drug strictly as directed by your doctor!
• When disposing of a spoiled medicinal product, no precautions should be observed.
• Keep the diluted solution away from children to avoid unpleasant situations.
• Cortexin solution should not be mixed with other drugs.
• In case of accidental skipping of the planned dose of the drug, the next dose should not be increased. You need to take the medicine further according to the previously drawn up schedule.
• There are no features for the introduction of funds.

Release form

Cortexin is available in pharmacies only in the form of injections. The lyophilisate required for medicinal solution, is used by injection directly into the muscles (injections are in ampoules for injection) 5 mg and 10 mg. The drug has only this form of release, others have not been observed so far.

Therefore, be careful if you notice other forms of Cortexin on sale, not in injections. This is most likely a fake tool, the use of which may be unsafe.

Pregnancy and lactation

Taking the drug for medical purposes during childbearing is completely contraindicated, so far no studies have been conducted on its safety. If it is required to use the drug during feeding, it is imperative to stop breastfeeding, also due to total absence research.

Reviews of patients about Cortexin

Reviews about Cortexin are extremely positive due to its high efficiency.

Aleksey I., 44 years old: “All his youth he suffered from epilepsy, no medicines helped, an attack came after an attack. I went to the district clinic, visited a doctor, and he prescribed Cortexin for me. I took it strictly according to the instructions and as a result, epilepsy attacks became less and less frequent and for 5 years they disappeared altogether. I recommend to all such patients as effective remedy with this disease."

Irina Alexandrovna, 57 years old: “Several years ago I got into a car accident, where only I was injured, but the driver and other passengers were not. I had a traumatic brain injury, after which there were gaps in my memory, frequent headaches. Cortexin injections were prescribed as one of the methods of treatment. The recovery was long, but sure: she underwent several courses of treatment with Cortexin. Now there are no health problems, thanks to Cortexin.

progipertoniyu.ru

Cortexin - instructions for use, reviews

Cortexin is a nootropic drug that has a tissue-specific effect on the cerebral cortex due to its optimally balanced composition of neurotransmitters and polypeptides.

pharmachologic effect

Cortexin has nootropic, neuroprotective, tissue-specific and antioxidant effects.

The nootropic effect of the drug lies in its ability to improve the higher functions of the brain, concentration, memory, facilitate learning processes, and develop resistance to a variety of stressful influences.

The tissue-specific effect of the drug lies in its ability to activate the metabolism of neurons of the peripheral and central nervous system. In this regard, against the background of the use of Kotrexin in patients, there is an improvement in the functions of the cerebral cortex and the state of the nervous system as a whole.

The neuroprotective effect of the drug is aimed at protecting neurons from the effects of various neurotoxic and endogenous factors. So, this drug reduces the toxic effect of the use of various psychotropic substances.

As for the antioxidant effect of the drug, it comes down to preventing or slowing down lipid peroxidation in neurons. Thus, the use of Cortexin contributes to the survival of neurons during hypoxia and oxidative stress.

Indications

Cortexin for children and for adult patients can be prescribed for the following indications for the use of this drug:

• neuroinfections of a viral and bacterial nature;
• traumatic brain injury;
• violations cerebral circulation;
• asthenic syndrome;
• complex therapy epilepsy;
• encephalopathy of various origins;
• complex therapy of encephalitis and encephalomyelitis;
• cerebral palsy;
• suprasegmental autonomic disorders;
• delayed speech and psychomotor development;
• decreased ability to learn;
• impaired memory and thinking.

Instructions for use (method and dosage)

According to the instructions for Cortexin, this drug is intended exclusively for intramuscular injection.

The contents of one vial with the drug is dissolved in one or two milliliters of the solvent. As a solvent can be used: 0.9% sodium chloride solution, water for injection or 0.5% solution of procaine (novocaine). Injections with Cortexin are done once a day. For adults, a course of Cortexin injections is prescribed lasting from 5 to 10 days. The adult dosage is 10 mg of the drug.

The dosage of Cortexin for children is different and depends on the patient's body weight. So, for children weighing more than twenty kilograms, an adult dosage of the drug can be prescribed. Children whose weight does not exceed twenty kilograms are prescribed injections at the rate of 0.5 mg of the drug per kilogram of body weight. According to the instructions for Cortexin, the drug can be used from the first days of a child's life.

The duration of the course of treatment and the dosage of the drug is determined by the attending physician individually for each patient. If necessary, a second course of Cortexin injections is repeated no earlier than after 1-6 months.

Contraindications

Contraindications to the use of this drug are: a history of allergic reactions to Cortexin, patient intolerance to other components of the drug, pregnancy and lactation.

Side effects

In rare cases, patients developed hypersensitivity reactions to the drug.

Attention!

The description of the drug posted on this page is a simplified version of the official version of the annotation for the drug. The information is provided for informational purposes only and is not a guide for self-treatment. Before using the drug, you should consult with a specialist and read the instructions approved by the manufacturer.

dolgojit.net

The use of Cortexin for the treatment of children - indications, instructions, reviews

Cortexin is a drug that stimulates brain activity. It is prescribed for children with any developmental disorders associated with insufficient blood circulation in the brain. In this review, you will find information about the composition, mechanism of action and for use, recommendations for dosage and medication. Attached are instructions for use, information about the manufacturer, forms of release and cost of the product, reviews of practitioners and patients, as well as a list of analogues.

Composition and mechanism of action of the drug

The main active ingredient of the drug is cortexin, which is obtained from the cerebral cortex of cattle. It contains proteins that are able to penetrate the porous barrier between the vessels and tissues of the nervous system and directly affect the child's brain.

Cortexin has a number of positive effects:

• improves cerebral circulation, prevents the development of hypoxia;
• stimulates metabolic processes, activates protein synthesis;
• prevents the manifestation of convulsions by reducing the sensitivity of the epileptic centers;
• is a powerful antioxidant - protects neurons from the harmful effects of free radicals, prevents cell destruction;
• accelerates the process of brain regeneration.

Cortexin is classified as a nootropic drug. This pharmacological group combines drugs that directly affect the tissues of the nervous system and affect higher mental functions. With its regular use in children, the ability to acquire knowledge, concentration and memory improves.

Indications for use

The drug is used in pediatrics and can be prescribed from the first days of a patient's life. Indications for use may be:

• cerebral palsy (as maintenance therapy);
• ZRR (delayed speech development);

• inflammation of the head or spinal cord;
• disorders of cerebral circulation;
• infectious diseases nervous system;
• traumatic brain injury;
• syndrome of diffuse brain injury.

Cortexin is prescribed to newborns with a diagnosis of perinatal CNS damage. This disease develops during pregnancy and is diagnosed in the first week of a child's life. In such children, there is a slow mental and motor development, a violation of the formation of reflexes.

Taking the drug allows you to saturate the neurons with oxygen and nutrients and in the future to avoid complications such as cerebral palsy or epilepsy.

Manufacturers, release forms and prices

The official manufacturer of Cortexin is the pharmaceutical company Geropharm, Russia.

The only form of release of the drug is a powder of white or light yellow, obtained by lyophilization (freezing of raw materials and subsequent placement in a vacuum). The drug is sealed in vials, which are opened immediately before preparing the solution.

There are 10 vials in a standard carton. The product can be packaged in 5 mg in a 3 ml container or 10 mg (5 ml). The package contains 2 plastic plates, divided by partitions into 5 individual cells each.

The shelf life of the medicine is 2 years. Store it in a dry, dark place at a temperature of 2-20°C. After opening the vial, prepare the solution and inject within 30 minutes.

The average cost of a package of 10 vials of 5 mg is 770 rubles, of 10 mg - 1175 rubles.

Dosage and administration

The doctor calculates the dose of the drug based on the age and weight of the child. Cortexin injections are best done in a hospital, but if the patient is treated at home, parents can dilute the powder and carry out the procedure on their own.

As a diluent, use 1-2 ml of 0.5% novocaine, or water for injection, or isotonic saline.

Novocaine reduces pain but may cause an allergic reaction. If the child tolerates injections well without anesthesia, dilute the powder with other liquids.

For children weighing less than 20 kg, the dose is prescribed at the rate of 0.5 mg per kg of body weight. If the child is heavier than 20 kg, give him 10 mg of the drug daily.

Before the first procedure, read the instructions (download instructions). Follow the dosage prescribed by your doctor.

The process of preparing the injection and administering the drug is simple:

1. Wash your hands with soap and wipe them with alcohol.
2. Draw the solvent into the syringe, pierce the cap of the powder bottle with a needle and pour the liquid into it. Point the tip of the needle towards the wall of the bottle so that the solution does not foam.
3. Leave the needle in the stopper, and disconnect the syringe from it for a while. Gently shake the contents of the vial until it acquires a uniform consistency without powder grains.
4. Attach the syringe back and draw up the desired volume of solution.
5. If the needle becomes blunt when inserted into the cork, replace it with a new one.

Administer the drug intramuscularly. For children under one year old, inject into the front of the thigh so as not to hurt the sciatic nerve. Older patients can inject the medicine into the gluteal muscle.

The course of therapy lasts no more than 10 days. During this time, administer the drug to the child once a day.

It is better to carry out the procedure in the morning, because Cortexin can excite the patient's nervous system and cause insomnia.

If necessary, the treatment can be repeated, but not earlier than 3-6 months after the end of the previous one.

Give the injection no later than half an hour after preparing the solution. Do not open the bottle and do not divide the powder into parts.

If, after the introduction of the required volume of the drug, a certain amount of the solution remains, do not reuse it.

The product is of natural origin and does not cause side effects. The only reason why the drug may be contraindicated is individual sensitivity to its components. Allergic children develop an itchy rash immediately or a few days after the first injection. In this case, contact your doctor. He will find out the cause of such a reaction and, possibly, he will select another drug with a similar effect to Cortexin.

Cortexin is a nootropic drug from the group of protein bioregulators. The action of the drug is based on its ability to normalize metabolic processes in the brain, resulting in the provision of antioxidant, anticonvulsant, nootropic, celebroprotective effects on the central nervous system.

Cortexin is presented in the form of a lyophilizate for the preparation of a solution for intramuscular injections; there are no tablets in pharmacies.

As an active ingredient, complexes of low molecular weight water-soluble peptides called cortexin are used.

The composition of 1 vial includes 5 (for children) or 10 (for adults) mg of Cortexin. As an auxiliary substance, glycine is used - an amino acid that improves metabolic processes in the brain area.

pharmachologic effect

The active substances of the Cortexin drug activate the neurons and neurotrophic factors of the brain, which leads to an acceleration and increase in the efficiency of information transfer between different structural elements. There is a decrease in convulsive activity and normalization of the bioelectric potential due to the optimization of the balance of amino acids, dopamine and serotonin.

The pharmacological activity of the drug Cortexin is due to the effectiveness of the active substances - proteins of small weight, which, after intramuscular infusion, penetrate into the brain and contribute to the following positive effects:

Cortexin also activates metabolic processes, improves the functional state of the central nervous system and increases tone. The drug prevents the formation of free radicals, optimizes the balance of metabolism of excitatory and inhibitory amino acids.

Indications

Cortexin is prescribed as part of complex treatment the following diseases and states:

• epilepsy;
• autonomic disorders;
• delays in speech and psychomotor development in children;
• asthenic conditions;
• encephalopathies of various origins;
• in acute or chronic encephalomyelitis and encephalitis;
• traumatic brain injury and possible complications;
• with various forms of cerebral palsy;
• with disorders of cerebral circulation;
• with a decrease in the ability to learn;
• with cognitive impairment, accompanied by memory impairment and thinking disorders.

The drug is not intended for self-medication, before using it is necessary to consult with your doctor.

Mode of application

The exact dosage of Cortexin and the course of treatment are determined by the doctor individually, taking into account the age of the patient and the characteristics of his body, as well as indications for the use of the drug.

Cortexin is intended for intramuscular injection.

1. Before the injection, the lyophilisate in the bottle must be diluted with 1-2 ml of a solution of Procaine or Novocaine (0.5%), water for injection or sodium chloride (0.9%).
2. The powder is diluted immediately before injection, since the finished medicine cannot be stored.
3. It is necessary to make an injection immediately after receiving the finished solution.

In the event that the next injection was missed, the use of a double dose of the drug is not recommended. It is necessary to make the next injection in the order indicated by the manufacturer, in the usual way.

How to do injections?

The finished solution is injected into the anterior wall of the abdomen, the anterior-lateral surface of the thigh (upper third), the outer upper third of the shoulder. In some cases, it is more convenient for patients to inject into the buttocks, while it should be borne in mind that this route of administration may slow down absorption. active component and the formation of painful seals at the injection site.

If there are no skills in intramuscular administration of the drug, it is recommended to entrust the procedure to a qualified medical worker.

Contraindications

From the use of Cortexin, it is necessary to refrain from individual intolerance to the components of the drug, as well as during the treatment of pregnant and lactating women. If the use of the drug during the treatment of a nursing woman is required, then it is necessary to interrupt breast-feeding during therapy.

Use in childhood

Cortexin can be used during the treatment of patients of younger age groups as prescribed and under medical supervision.

1. The drug is used for motor, speech or mental delays development, with perinatal damage to the central nervous system.
2. The drug is prescribed in order to correct the behavior of a small patient: to eliminate increased irritability and nervousness.
3. The use of Cortexin during the treatment of schoolchildren improves memory, develops thinking, and increases concentration.
4. Cortexin injections are prescribed for children who have suffered trauma, hypoxia, prolonged stress.

The dosage of the drug is selected taking into account the body weight of the child. The medicine must be used once every 24 hours, the course of treatment is determined individually.

Important! The powder in the vial is not intended for division, the drug should be used once. In the event that part of the medicine has not been used completely, the remnants must be disposed of and the next time a new vial of medicine should be used.

Adverse reactions

The medicine is well tolerated. In rare cases, hypersensitivity reactions have been reported during the use of Cortexin.

Interaction with other drugs

There were no cases of significant drug interaction Cortexin with other groups of medicines. The drug is used as part of complex treatment regimens prescribed by a doctor.

The decision on what is better to use: Cortexin or Mexidol, Piracetam, Cerebrolysin can only be taken by the attending physician, as well as the possibility and expediency of the simultaneous use of the drug with Actovegin or Pantogam. All the described drugs contribute to the provision of nootropic effects, but have different mechanisms of action.

Patients are strongly advised to refrain from self-medication and self-selection of other medicines! Clinical cases are different, treatment regimens are selected strictly individually after a comprehensive examination.

The finished product is not intended for storage or use after storage.

Cortexin helps to increase concentration, so it can be used by those categories of people whose professional activity requires heightened attention and rapid psychomotor reaction.

In the event that Procaine or Novocain is used as a solvent, it is necessary to pay special attention to the instructions for these drugs and carefully study the manufacturer's instructions regarding contraindications, age restrictions etc.

Storage of the drug must be carried out in accordance with the manufacturer's recommendations: a dry place protected from sunlight in compliance with the temperature regime (2-20 degrees).

The release of the drug is carried out after the presentation of a prescription from a doctor.

Analogues, cost

The cost of the drug Cortexin for the period August 2017 is:

Cortexin has no exact structural analogues. If it is necessary to select a replacement, it is necessary to discuss with the doctor the possibility of using other nootropic drugs: Cavinton, Ginkgo Biloba, Vinpocetine, Nootropil, Omaron, Pantogam, Cerebrolysin.

Reviews

“I turned with the child to a neurologist with complaints of excessive emotionality, the doctor examined the baby and wrote out a prescription with drugs, among which was Cortexin for children. I have heard more than once that Cortexin's injection is called a "talker". After opening the package, I found small vials of medicine that need to be diluted with painkillers or sodium chloride. The injections were given by a nurse in the treatment room. The effect is good, but unfortunately, the child had an allergic reaction. The injections were given daily, only 7 injections out of 10 were made, after which the course of treatment had to be stopped. Now I see that the child’s memory has significantly improved and concentration of attention has increased: he quickly remembers rhymes, he retells the studied material with high accuracy.

Valentine

“In elementary school, my daughter had big problems with learning and memorizing the material. At preschool age, the child began to talk late, in the 1st grade she still did not know how to read. At the same time, all the doctors wrote that the daughter was healthy and there were no problems. As a result, we got to a sensible neurologist, who prescribed Cortexin injections. After the first injection with Novocain, she went severe allergy- but this is a reaction to the anesthetic element! After that, she diluted with saline and no allergic reactions was no more. It is necessary to carefully study the instructions for the solvent. There is an effect - the child began to memorize much better, he does the lessons faster, the grades improve. A course of injections with Cortexin every 3 months + injections of Encephabol and Cogitum is recommended.

Valeria

“At 1.5 years old, the child only said “mom”, “dad”, I heard more than once that this is not a problem and, therefore, will speak later, but time passed and by 2.5 years the situation did not improve. We went to the doctor, she prescribed Cortexin.

The child tolerated injections very badly, constantly cried, 3 days after the start of the course of treatment he said that he was afraid to go for injections. I was taken aback, because it was almost the first phrase spoken by my son. The medicine began to work, after a few days other new words appeared. By the age of 3, the baby learns and retells rhymes and children's fairy tales. And to all parents who have such a problem, I recommend not to delay and consult a doctor in a timely manner. I met a lot of reviews that Cortexin helps many children to “talk” and also improves memory well, increases concentration.”

Tatiana

“From birth, the child was diagnosed with the development of hydrocephalic syndrome, after treatment with actovegin, diacarb and asparkam, there were improvements. But the planned vaccination with DTP, polio - and again a rollback and worsening. The doctor said that the vaccination had an effect and prescribed 10 injections of Cortexin. The effect is very fast, after a few days the child began to sit down, tried to crawl, and after that he began to stand on his legs. Many mothers say that after these injections, the children begin to sit, and walk, and babble. The medicine is not cheap, but the effect is worth it, now we go for massages, we plan to repeat the course of treatment if necessary.”

Marina

“I give injections of Cortexin to a child every six months after minimal brain dysfunctions and delays in speech development have been identified. regular classes, physical exercise, physiotherapy and medicines immediately entered the life of the baby, he is already used to the fact that his mother regularly gives injections and reacts calmly. By the age of 5, the child reads a little, knows numbers, but simple examples and tasks are still not easy. After each course of treatment, as well as before each trip to the doctor, I always talk with the child, explain everything to him, who, if not the mother, will psychologically set the child up for the need for treatment.

Natalia

“Cortexin injections together with Actovegin were recommended by a neurologist after she turned to him with complaints of weakness, low blood pressure, general malaise and dizziness. I don’t know which drug worked better, but there is an effect. Cortexin injections are quite painful, the pain radiates to the leg. But it's worth it: well-being has improved significantly, nerves are no longer naughty, memory has improved, stress resistance has increased. In general, attitudes towards many life situations which I am very happy about.”

Irina

“A course of injections of Cortexin was prescribed to a one-year-old child with a delay in speech development. The medicine was used for 10 days, as a result - no effect. All the injections were given in the hospital, the child cried a lot, and the lack of results was especially upsetting. The doctor explained that the effect may not appear immediately, it will take several weeks or even months. A second course was recommended already at the age of 2 years, but after consulting with another specialist, I decided that I would not inject such a drug for a child. It turned out that the active substances are obtained from the cerebral cortex of cattle, the medicine is painful and it is better to use it with painkillers (novocaine, procaine) - the doctor advised with saline. As a result, the child began to talk on his own when the use of all drugs was canceled.

• Latin name: Cortexin
• ATX code: N06BX
• Active substance: Animal cerebral cortex polypeptides
• Manufacturer: Geropharm LLC, Russia

Compound

Release form

The drug is available as a sterile lyophilized powder for solution for intramuscular injection.

The cardboard package is completed with two blister packs, each of which contains 5 vials of lyophilisate, and instructions for use.

In pharmacies, you can buy Cortexin 10 mg No. 10 and Cortexin 5 mg No. 10.

Cortexin 10 mg is available in 22 mg vials of 5 ml. The drug is intended for the treatment of adult patients.

Cortexin 5 mg was created specifically for use in pediatrics. It is available in 11 g bottles with a capacity of 3 ml.

pharmachologic effect

Cortexin belongs to the group nootropic and gamkergic drugs that mainly affect CNS . Against the background of its application are noted:

• nootropic ;
• neuroprotective ;
• antioxidant ;
• tissue-specific effects.

Pharmacodynamics and pharmacokinetics

Cortexin is a bioregulator with a polypeptide structure, which is a complex of water-soluble neuropeptides . The molecular weight of these polypeptide fractions does not exceed 10 thousand daltons, which allows them to penetrate the physiological barrier separating central nervous and circulatory system .

The mechanism of action of the drug is realized due to:

• activation of regulatory , neurons and brain neurotrophic factors ;
• ratio normalization amino acids , performing mediator functions of excitatory and inhibitory types of action, as well as important brain neurotransmitters and serotonin ;
• moderately pronounced GABA-ergic effect;
• reducing the level of paroxysmal (paroxysmal) convulsive activity brain and the ability to normalize the indicators of its bioelectrical activity;
• preventing the formation of oxidative degradation products lipids (free radicals).

The nootropic effect of Cortexin is accompanied by an improvement higher brain functions , improving memory, increasing the ability to learn and stress resistance.

The neuroprotective effect is manifested in the ability of the agent to increase tissue resistance. brain to the damaging effects of various endogenous neurotoxic factors and reduce the toxic effects of neurotropic substances.

Antioxidant action manifests itself in the ability of the drug to influence oxidative stress (cell damage provoked by oxidative processes) and increase the survival rates of neurons under conditions of oxygen starvation.

The mechanism of this action is associated with the suppression of free radical processes and peroxide lipid oxidation of cell membranes , as well as with the correction of oxygen-dependent pathological conditions.

As a result: the destruction process slows down cell membranes improves microcirculation, decreases vascular wall permeability , normalizes the level contained in the blood and triglycerides .

The tissue-specific effect of the drug is associated with an increase in the intensity CNS neurons and PNS , stimulation of reparative processes in CNS , improvement of the functional state cerebral cortex and general tone somatic and autonomic nervous system .

Pharmacokinetic characteristics are not given to determine, since the disintegration time of the constituents active substance Cortexin of L-series amino acids and neuropeptide fractions is no more than 3 minutes.

This makes it impossible to establish the rate and degree of absorption of peptide residues, their distribution over various organs and tissues, as well as the rate and ways of their excretion from the body.

Indications for the use of Cortexin: from what medicine is prescribed for adults and children

Indications for the use of the drug are:

• provoked bacteria or viruses infectious diseases nervous system ;
• conditions associated with impairment circulation in the brain ;
• TBI and its consequences;
• diffuse brain injury syndrome different nature of origin;
• cerebral (suprasegmental) autonomic disorders .

In combination with other drugs, the drug is prescribed for the treatment, as well as for the treatment acute and chronic inflammatory diseases brain and/or spinal cord various etiologies.

For children, indications for the use of Cortexin are reduced learning ability, impaired memory and thinking, child delay syndrome psychomotor and speech development (ZPRR), various forms cerebral palsy .

Contraindications

The drug is contraindicated in patients with hypersensitivity to cortexin and/or glycine.

Clinical studies to establish the effect of the drug on the body of a pregnant woman and a developing fetus have not been conducted. For this reason, the drug is not recommended for use at any time.

Since the data clinical research regarding the use of the drug during the period are absent, if necessary, the appointment of Cortexin breastfeeding is recommended to stop.

Side effects of the drug

Potentially possible side effects are due to individual sensitivity to the components that make up the drug.

Cortexin injections, instructions for use (Method and dosage)

The drug is intended for injection into the muscle.

How to breed Cortexin?

Before injection, the powder contained in the vial should be diluted with one or two milliliters of a 0.5% solution (), physiological saline (isotonic sodium chloride solution (0.9%)) or water for injection.

To prevent the formation of foam, while trying to direct the needle to the wall of the vial.

How to inject a child with Cortexin?

Cortexin is allowed to be prescribed from the first days of life. In some situations, parents have to give the child injections on their own. And here questions arise how to properly inject Cortexin and what is the best way to dilute the powder.

Before giving an injection, water for injection is drawn into the syringe, novocaine or saline , then pierce the lid of the vial and pour the collected liquid into it.

The syringe should be removed (the needle remains in the cap) and the contents of the vial should be shaken thoroughly until the powder is completely dissolved. After that, the syringe is reattached and the required amount of solution is drawn into it.

For an injection, it is better to take a new needle, since the needle with which the solvent for the lyophilizate was injected may already be fairly dull.

The medicine is administered slowly, as rapid administration can cause very severe pain.

For babies up to six months, an intramuscular injection is made into the front surface of the thigh (so as not to accidentally damage the sciatic nerve).

For children, especially very young children, all injections are made with saline or water for injection. injections with novocaine less painful than injections saline , however, dilute the drug novocaine allowed only if there is a firm belief that this will not cause allergic reaction The child has ( novocaine able to give the strongest allergy and ).

Like others neurometabolic drugs , It is recommended to inject Cortexin before 12 noon, given its activating effect and the ability to provoke psychomotor agitation .

Instructions for use Cortexin for adults

Cortexin injections are given to adult patients once a day, daily for ten days, at a dose of 10 mg.

At massive ischemic stroke (MII) in the acute phase, as well as in the early recovery period, the indicated dose is recommended to be administered to the patient twice a day (morning and evening) for ten days. Ten days later, the course should be repeated.

Instructions for use Cortexin for children

AT pediatric practice the medicine is used to treat children from the first days of their lives.

For patients whose weight does not exceed 20 kg, the drug is prescribed at a dose equal to 0.5 mg / kg of body weight. For patients weighing more than 20 kg, a dose of 10 mg is indicated.

The duration of treatment is ten days. If necessary, after three to six months, the patient may be assigned a second course.

The drug rarely causes side effects, has almost no contraindications and can be used to treat even newborn babies. Its main disadvantage is the release form: Cortexin is not available in tablets, and this partly complicates its use in children if the latter require several courses.

Overdose

To date, there are no reports of side effects that have developed as a result of an overdose of Cortexin.

Interaction

The drug is incompatible with drugs that have a peptide structure.

Terms of sale

The drug belongs to the category of prescription drugs and should be dispensed from pharmacies only on prescription.

Storage conditions

Cortexin should be stored in a dry, protected from sunlight places at temperatures from 2 to 20 ° C.

Best before date

Suitable for use within 36 months from the date of manufacture.

special instructions

The drug is produced exclusively in the form of a lyophilisate, Cortexin is not produced in tablets.

The drug should not be mixed in the same syringe with any other drugs.

Cortexin's analogs

Cortexin analogs in tablets: Armadin and Armadin Lone G, Borizol , Rilutek , .

Cortexin analogs in ampoules: Armadin , Mexiprim , Neurotropin , Nikomex , Nucleo CMF Forte , Cytoflavin .

Cortexin or Cerebrolysiin - which is better?

Studies conducted on laboratory rats have shown that Cortexin, when administered intraperitoneally and injected into lateral ventricle of the brain have a similar effect.

A comparative analysis of the central effects of the drugs led to the conclusion that, despite their similarity, Cortexin is more active.

At the same time, it provokes a much smaller number of adverse reactions and can be used from birth (whereas Cerebrolysin in pediatric practice is used in the presence of reasonable indications).

According to some patients, injections Cerebrolysin less painful in comparison with Cortexin injections.

Cortexin for children

Instructions for use Cortexin for children allows the use of this drug from the first days of a child's life.

Reviews of doctors on Cortexin for children confirm the manufacturer's statements that the drug practically does not cause adverse reactions, does not teratogenic and carcinogenic and well tolerated by patients.

Its use in neurology, neonatology and pediatrics can improve the behavior of the child and his general state with various kinds of tones, normalize memory function and speech, relieve headaches.

Reviews about Cortexin

Cortexin is a drug widely used in neurological practice. Reviews about Cortexin for adults, which can be found on numerous thematic forums, testify to the effectiveness of the use of this remedy for the treatment of patients with the most different ages(both for infants and for people of senile age).

Taking the drug allows you to speed up the recovery process after injuries and, and in older people stimulates work brain , increases the ability to memorize and concentrate, and also prevents the decline in intellectual abilities.

Reviews about Cortexin for children allow us to conclude that the drug is most often prescribed for children who have certain deviations in neuropsychic development. In particular, indications for the use of the drug are cerebral palsy and brain damage that occurred in the prenatal period (close to the date of birth) or directly during childbirth.

Injections for children - and reviews of Cortexin confirm this - make it possible to achieve significant improvements: after a course of treatment with the drug, the child becomes calmer, he has an improvement brain activity, interest in learning increases, memory and speech improve.

The use of the drug for infants (in particular, for newborns born prematurely) allows you to notice obvious improvements in a fairly short time, which manifest themselves in a calmer behavior of the child or the emergence of new skills in him (for example, the ability to independently roll over from his back to his tummy and back).

Mothers whose children were prescribed Cortexin note that after the course of treatment, the child literally “came to life before our eyes”. The advantages of the drug, many consider the absence side effects and low drug toxicity. As disadvantages, the rather high price of the drug and the pain of injections are most often indicated.

Nootropic drugs are widely used in pediatric practice to improve brain activity, activate metabolic processes in the brain. One of the frequently prescribed is Cortexin, suitable even for newborns. It helps to reduce the backlog of the child in neuropsychic development, stimulating cognitive processes: speech, thinking, memory. In addition, babies tolerate the use of this drug quite well.

Action and composition of Cortexin

Cortexin is a nootropic drug related to protein bioregulators. eponymous active substance- a complex of soluble polypeptide fractions extracted by acetic extraction from the cerebral cortex of pigs and cattle.

The component easily overcomes the barrier between circulatory system and the central nervous system, penetrating through the capillaries of the brain to nerve cells. This allows the drug:

• protect neurons from the harmful effects of free radicals, lack of oxygen, increase resistance to toxic substances;
• improve the cognitive functions of the brain, making it easier for the child to perceive and remember information, learn, concentrate;
• reduce the excessive activity of epileptic centers in the cerebral cortex, thereby preventing convulsive phenomena;
• slow down oxidation by oxygen fatty acids, increasing the survival of neurons in hypoxic conditions;
• activate metabolic processes in the central nervous system, improving the functionality and active state of the cerebral cortex.

The drug is produced in the form of a lyophilized powder. white-yellow color, which is intended for the manufacture of the solution. There are no other forms of release, including tablets and capsules, in the Cortexin line of medicines.

In pharmacy chains, you can find two types of medicines: for adults and for children. They are no different, except for the amount of powder in the ampoule (10 and 5 mg, respectively). For the treatment of small patients, both options are suitable, but the doctor should choose the right dosage.

Indications for use

Cortexin is used to treat conditions such as:

• damage to cells and tissues of the brain of various origins;
• traumatic brain injury;
• epileptic seizures;
• reduced ability to learn and remember;
• delayed mental or motor development;
• cognitive impairment;
• acute or chronic encephalitis;
• increased fatigue;
• delay in the formation of speech skills;
• severe symptoms in cerebral palsy;
• hydrocephalic syndrome.

The popular name of the drug is “talker”, because after using it, a previously silent child begins to actively talk, memorize new information faster, memorize poems with ease. Stuttering disappears, and speech becomes smoother and clearer.

Dr. Komarovsky about the "memory medicine" - video

Cortexin for newborns and children up to a year

The perinatal, or perinatal, stage begins at 28 weeks of fetal development and ends a week after birth. At this time, the fetus faces numerous dangers: hypoxia, infections, intoxications, etc. Yes, and the birth itself is also a dangerous event for the child.

Perinatal CNS damage is a fairly common diagnosis among newborns. In such babies, there is a slowdown in the pace of mental and motor development, and problems with speech appear in the future. A favorable prognosis largely depends on how and when treatment began.

Cortexin is prescribed from the first days of a child's life, so that PCNS does not develop into severe illness central nervous system in the form of cerebral palsy or epilepsy. Due to its natural origin, the drug does not have a toxic effect and acts quite gently, so it is often necessary to take several courses to achieve a satisfactory result.

Instructions for use: how to dilute and inject Cortexin

The pediatrician prescribes the dosage and frequency of taking the medication based on the body weight of the child. It is strictly forbidden to make adjustments to the prescribed course of treatment at your own discretion - this can only aggravate the state of children's health.

Intramuscular injections are best done on an outpatient basis, but sometimes parents are forced to inject their child on their own. Therefore, questions are not uncommon: how to inject Cortexin and how to dilute the powder.

• 0.5% novocaine solution;
• isotonic 0.9% sodium chloride solution;
• injection water.

For children, injections with saline or water are more suitable. Novocaine helps to reduce the pain of the procedure, but significantly increases the likelihood of allergic reactions. Therefore, it is allowed to dilute Cortexin with an anesthetic only if the child can hardly tolerate nootropic injections and does not have novocaine.

To properly dilute the powder, you must:

• draw the injection solution into the syringe, pierce the stopper of the ampoule with the medicine with a needle and pour the collected liquid into it (we direct the needle to the wall of the vial to avoid foaming);
• remove the syringe (leave the needle in the cork) and gently shake the contents of the ampoule, achieving complete dissolution of the drug;
• attach the syringe and draw the required amount of a homogeneous solution into it (for injection, it is better to choose a new needle, since the previous one could become dull when the liquid is injected).

It is necessary to put an injection in the first half of the day. The fact is that Cortexin can have a stimulating effect, so an evening injection can lead to problems with sleep at night.

It is strictly forbidden to divide the powder into parts, it is necessary to dilute the entire contents of the vial and only then select the volume necessary for a single injection to the child. The remaining solution is thrown away, for the next injection, you need to repeat the algorithm described above.

If a child falls ill during treatment with Cortexin, you should consult a doctor about discontinuing the medication. Usually when high temperature and other obvious signs of a cold, nootropic injections are stopped until the baby is completely recovered.

The duration of the treatment course is 10 days. You can repeat the therapy after 3-6 months.

Contraindications and possible side effects

A nootropic agent is prohibited for use if the child has an individual intolerance to cortexin or glycine (an auxiliary component).

The instructions for the drug noted that the drug has no side effects, however, the reviews of parents show that in some cases Cortexin causes in children:

• allergic reactions (as skin rashes, itching, swelling);
• nervousness, tearfulness.

Undesirable effects often appear when using novocaine for the preparation of an injection solution. If the powder is diluted with saline or water, the likelihood of allergic reactions is significantly reduced.

How to replace Cortexin

Cortexin does not have complete analogues containing the same active substance. In the pharmacy network, you can buy substitute drugs that have a similar effect, but they contain other components. Remember that you can use nootropics only after consulting a pediatrician.

Substitute drugs - table

What can replace Cortexin - gallery

Encephabol is one of the most well-known and frequently prescribed nootropics for children. Pantogam is a nootropic agent with neurometabolic, neuroprotective and neurotrophic properties. Piracetam is used in the treatment of children with a slight disruption of the brain Actovegin belongs to the group medicines that affect the processes of tissue metabolism Cerebrolysin - a drug that stimulates neurometabolic processes

Doctors' opinion

On medical forums there are conflicting reviews and opinions of experts about nootropics in general and Cortexin in particular. Some doctors consider "medicines for the brain" a real panacea, others point to the unproven effectiveness of such drugs.

Neurologist Victor Koss endorses the use of nootropics in the treatment of neurological diseases:

If translated literally, it turns out "nutrition of the brain." As a rule, it is understood that the cells of the cerebral cortex can absorb the necessary amino acids, vitamins and trace elements to maintain life. The effectiveness of the use of nootropics has been proven by practice in neurology, amino acid and peptide preparations are very popular today.

Pediatrician Evgeny Komarovsky points out that nootropics are widely used in pediatric practice, but only in the territory of the former Soviet Union:

Despite the vast experience of use, despite the many positive properties found in experiments, despite the extreme attractiveness of the identified pharmacological effects and the breadth of indications for use, and so, despite all this, to substantiate the benefits and effectiveness of nootropic drugs using methods evidence-based medicine so far no one has succeeded.