Nifuroxazide lf instructions for use. Nifuroxazide syrup: instructions for use, how the drug works and when to take it

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Prices on NIFUROXAZIDE in the cities of Ukraine

Vinnitsa 51.25 UAH/pack.

NIFUROXAZIDE ..... 36.5 UAH / pack.
« WHOLESALE PHARMACY» Vinnitsa, ave. Youth, 20/73, phone: +380800505911

Dnieper 55.29 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« PHARMACY 9-1-1» Dnipro, blvd. Zvezdny, 1A, tel.: +380800505911

Zhitomir 44.68 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« WHOLESALE PHARMACY» Zhytomyr, st. Pokrovskaya, 151, phone: +380800505911

Zaporozhye 55.72 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« WHOLESALE PHARMACY» Zaporozhye, st. Novokuznetskaya, 40A, phone: +380800505911

Ivano-Frankivsk 55.47 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« PHARMACY 03» Ivano-Frankivsk, st. Chernovol Vyacheslav, 60/1, tel.: +380800505911

Kyiv 57.87 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« WHOLESALE PHARMACY» Kyiv, st. Vasylkivska, 5/7, phone: +380800505911

Kropyvnytskyi 45.91 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« WHOLESALE PHARMACY» Kropyvnytskyi, st. Rodimtseva Generala, 1, tel.: +380800505911

Lutsk 51.09 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« WHOLESALE PHARMACY» Lutsk, ave. Will, 5/1, phone: +380800505911

Lviv 62.48 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« WHOLESALE PHARMACY» Lviv, st. Pasichnaya, 70, phone: +380800505911

Nikolaev 57.84 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« WHOLESALE PHARMACY» Nikolaev, st. Cosmonauts, 142/5, phone: +380800505911

Odessa 57.34 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 35.6 UAH/pack.
« PHARMACY FROM WAREHOUSE» Odessa, st. Petrova Generala, 16, tel.: +380487778418

Poltava 46.64 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« PHARMACY PRANA» Poltava, st. Mazepa Ivan, 49, phone: +380800505911

Smooth 54.47 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« WHOLESALE PHARMACY» Rivne, st. Cathedral, 336, phone: +380800505911

Sumy 48.95 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« PHARMACY PRANA» Sumy, st. Kondratiev Gerasim, 181, tel.: +380800505911

Ternopil 56.78 UAH/pack.

NIFUROXAZIDE tab. p / captivity. shell 200 mg blister in pack No. 10, Arterium Corporation ..... 36.5 UAH / pack.
« WHOLESALE PHARMACY» Ternopil, st. Kupchinsky, 14V, tel..

Nifuroxazide is a bactericidal and antibacterial drug intended for the treatment of diarrhea in children. It is available in tablet and liquid form. In the second case, the drug is called a suspension, solution, syrup. A thick yellow mass with a banana smell is pleasant to the taste. The drug is not an antibiotic, it belongs to the group of nitrofurans.

Nifuroxazide: indications and contraindications

Nifuroxazide is an antidiarrheal drug that eliminates diarrhea of ​​​​any type and nature:

• Acute / chronic diarrhea associated with the activation of strepto- and staphylococci, salmonella, klebsiella and other microorganisms.
• Diarrhea caused by prolonged use of antibiotics.
• Diarrhea that opens with appendicitis, food poisoning or autoimmune gastritis.
• Toxic diarrhea in 2-month-olds and older children.

In addition, the syrup is prescribed for intestinal dysbacteriosis, colitis and enterocolitis, as well as for the prevention of infection after surgical intervention in the intestinal tract.

Contraindications to taking the drug are covered by the instruction. Their number is:

1. age up to 2 months;
2. prematurity;
3. deficiency of enzymes that break down sucrose (the restriction applies to children under the age of 1 year);
4. allergy to Nifuroxazide (reactions are expressed by itching, rash on the body, shortness of breath).

For other categories of children, the suspension is measured in accordance with the summary sheet. You can use it without fear for the deterioration of the intestines. Occasionally, after the use of Nifuroxazide, nausea or vomiting occurs in children.

How to give Nifuroxazide to children

Since Nifuroxazide suspension is capable of exfoliating, the instruction suggests shaking the vial before treating children.

Parents can choose the optimal dosage based on age and the severity of the disease. The printed instruction gives the exact amount of the remedy that should be given to a sick child at a time.

• Baby aged 2 - 6 months. syrup give 2.5 or 5 ml 2 r. per day at intervals of 12 hours.
• From the 2nd half of life to 6 years, the dosage is increased. The instruction suggests giving children a solution every 8 hours, 5 ml each.
• After 6 years, the suspension is issued 4 p. per day, i.e. every 6 hours the child receives 5 ml of the drug.

Nifuroxazide is given to children either with meals or between meals. This factor does not affect the absorption of the active substance.

But doctors recommend that kids follow a diet that requires the exclusion from the diet of juices, raw vegetables and fruits, as well as fatty, spicy and any food that is difficult to digest.
Useful for indigestion mineral water, saline solutions, weakly brewed unsweetened tea.
The instruction recommends antidiarrheal therapy for 5 to 7 days.

Special instructions for treatment with Nifuroxazide

If after 3 days from the start of taking the drug, the mother understands that he did not help, and the general condition of the child worsened, the advisability of further therapy should be discussed with a specialist. The following symptoms require immediate medical attention:

1. vomit;
2. temperature rise;
3. exit with feces of mucous or bloody impurities;
4. signs of dehydration - lethargy, small portions of urine with frequent trips to the toilet "in a small way", dry lips and tongue.

Nifuroxazide: Equivalent drugs for diarrhea

The remedy for diarrhea Nifuroxazide has several analogues. Drugs in different forms contain the same active ingredient - nifuroxazide:

• Stopdiar tablets;
• Nifuroxazide Richter - tablets and solution;
• Ecofuril and Ersefuril capsules;
• Lecor - capsules and suspension;
• Enterofuril - capsule and liquid form.

Diarrhea is a symptom characterized by the appearance liquid stool, increased peristalsis of the gastrointestinal tract, the occurrence of discomfort in the abdomen. Often, such disorders are associated with the penetration of pathogenic microorganisms and their reproduction in the lumen of the gastrointestinal tract. It has its own characteristics in children due to the rapid dehydration of the body and the occurrence of concomitant complications. Let's figure out how to deal with stool disorder with the help of Nifuroxazide for a child.

Pharmacological features

"Nifuroxazide" is an antimicrobial drug from the group of nitrofurans, mainly used as an intestinal antiseptic. The mechanism of action of this drug is based on the inhibition of dehydrogenases and cellular respiration.

In addition, "Nifuroxazide" disrupts the processes of protein synthesis in the cell, which disrupts the vital activity of the microorganism.

Pharmacodynamics

When taken orally, the drug has low bioavailability, that is, it is practically not absorbed into the systemic circulation. In the blood plasma, trace concentrations of nifuroxazide can be detected, while a small amount of it is excreted by excretion in the urine unchanged. The rest is allocated from stool. Due to practically total absence absorption rate of drug excretion depends on the dose taken and the intensity of intestinal motility.

The spectrum of action of the drug

Referring to nitrofuran derivatives, Nifuroxazide has a bacteriostatic effect at medium therapeutic concentrations, and at higher doses it acts as a bactericidal drug with a slow development of resistance. Too sensitive to the drug a large number of both gram-positive (streptococci, penicillinase-producing staphylococci) and gram-negative microorganisms ( coli, Salmonella, Shigella, Klebsiella, Enterobacteriaceae). In addition, the medication negatively affects various viruses, Trichomonas, Giardia and fungi of the genus Candida. The drug retains its effect in the presence of pus and other tissue decay products in the wound.

"Nifuroxazide" is ineffective in the treatment of pseudomonas infections, as well as infections caused by microorganisms of the genus Proteus.

Indications for the use of the drug "Nifuroxazid" (instruction for children)

The main indication for prescribing the drug are various infections of intestinal localization caused by pathogens sensitive to the antibacterial drug. "Nifuroxazide" is prescribed for acute stool disorder of infectious origin, chronic inflammatory diseases intestines and enterocolitis. The drug is prescribed to patients with infected wounds (possibly topical application medicinal product), as well as surgical interventions on the intestines (for sanitation) and with complex treatment dysbiosis.

It should be noted that in pediatric practice The most commonly used drug for is Nifuroxazide. Instructions for children, with the exception of dosage, are similar to those for adults.

Dosage and administration

The use of the drug is carried out regardless of the meal. For the treatment of adults, as well as children after the age of seven, the drug is taken 1 tablet (200 mg) three or four times a day. This dose per dose corresponds to 5 ml of suspension or syrup "Nifuroxazide". Instructions for use for children and adults says that after normalization of the stool, the drug should be continued for 3-4 days. The course of treatment should not exceed a week. If the drug is ineffective for a long time, the approach to therapy should be reconsidered.

For preschool children, the dosage should be reduced to 100-150 mg per dose of Nifuroxazide. Syrup for children is an excellent treatment option. At the same time, the frequency of application of the agent remains the same. If there is no medicine in the form of a syrup at hand, you can gently crush half a 200 mg tablet between two tablespoons to a powdery consistency and give the baby with a little water or breast milk. In all other cases, it is recommended to use liquid Nifuroxazide (suspension for children).

Side effects

When using drugs of the nitrofuran group, adverse reactions most often occur from the digestive tract, which is directly related to the site of action of the drug. When taking the drug "Nifuroxazide" for a child, there is a risk of developing dyspeptic disorders, cholestasis, hepatitis. With a low degree of probability, there may be a manifestation of the reaction of individual intolerance to the drug by patients, which is accompanied by the occurrence of nausea, vomiting, abdominal pain, diarrhea. In the latter case, with a slight exacerbation of symptoms, treatment should not be stopped, since negative manifestations pass quickly and are associated with the onset of the drug. In the presence of severe symptoms and deterioration of the general well-being of the patient, the drug should be discontinued.

The undesirable effect of the drug on the central nervous system is marked by the appearance of neuritis. allergic reactions manifest in the form of a skin rash, itching, urticaria, pustulosis. In severe cases, hypersensitivity reactions may occur, including anaphylactic shock or angioedema. Taking the drug is rarely accompanied by disorders of the hematopoietic system.

Special instructions for taking the drug

Recall that therapy with the use of the drug "Nifuroxazide" should not last more than 7 days. In the case of incessant which cannot be stopped for three days, it is necessary to reconsider the tactics of treatment in the direction of prescribing antibiotics. In case of severe diarrhea and the presence of symptoms of dehydration, rehydration therapy and concomitant symptomatic treatment are carried out in parallel with the appointment of Nifuroxazide.

The composition of the drug includes lactose, so patients suffering from a violation of the digestion of this substance, the use of the drug should be limited or completely discontinued. Against the background of taking Nifuroxazide, it is not recommended to prescribe other oral agents due to a decrease in their effectiveness, which is associated with the presence of sorption properties. active substance. When using the medication, alcohol is contraindicated, as this can lead to the occurrence of which are accompanied by disorders from the central nervous system(noise and ringing in the ears), hyperemia skin, tachycardia, feeling of fear.

According to official information on the drug "Nifuroxazide" (instruction), a suspension for children and syrup can reduce the manifestation adverse reactions from the intestines.

Use during pregnancy and lactation

There are no unequivocal data that indicate the dangers of taking the drug during pregnancy and lactation. Given that Nifuroxazide is not absorbed from the lumen of the gastrointestinal tract and does not penetrate into breast milk, the appointment of such a drug is possible if the potential positive effect for the mother's body is higher than the effect on the fetus.

Poisoning and overdose

Due to low bioavailability, symptoms of poisoning are unknown. When taking large doses of the drug, it is recommended to wash the stomach and immediately seek qualified medical help.

Release form

On the pharmaceutical market, Nifuroxazide is available as a suspension for oral administration (200 or 220 mg of the active substance in 5 ml of suspension, 90 ml vial), tablets for oral administration(100 or 200 mg in 1 tablet) or capsules (200 mg of the drug in 1 capsule). Each patient can choose for himself the appropriate form of release.

In what form is Nifuroxazide most often bought? Syrup for children is more in demand, because babies are more prone to intestinal infections.

Synonyms

The drug is also available under the name "Enterofuril", "Ercefuril" in the form of capsules (100 or 200 mg each) and a suspension for oral administration containing 200 mg of the active substance (nifuroxazide) in 5 ml. Instructions for use for children of analogues are practically no different from the original. However, before using the drug, it should still be carefully studied.

"Nifuroksazid" for children: reviews

This drug is used not only in pediatrics, but also in the practice of internal medicine. Almost all reviews about the use of Nifuroxazide in children are positive. This is due to its effectiveness in the treatment of various disorders of the functioning of the gastrointestinal tract, as well as the presence of conveniently dosed forms of the drug in the form of a suspension and syrup.

In addition, "Nifuroxazide" for a child is a fairly safe drug, which leads to its widespread use in clinical practice.

Conclusion

"Nifuroxazid" for a child is the most effective drug, which helps to quickly cope with diarrhea of ​​​​infectious genesis. The safety of the drug is due to its low bioavailability, and high efficiency due to its action only in the lumen of the gastrointestinal tract. According to the official information on the drug "Nifuroxazide" (instruction), suspension for children and syrup are the preferred forms. Tablets, as a rule, are prescribed for adults.

A.07.A.X.03 Nifuroxazide