Curantyl official instructions. The use of Curantyl during pregnancy: detailed instructions

Developing disorders of blood microcirculation in the vessels make themselves felt in a variety of ways. Someone's legs hurt, and in order for the pain to stop, you need to stop and sit down to rest. Someone needs blood thinners because there is a risk of developing a myocardial infarction, or the person has problems in functioning of cardio-vascular system. In all these cases, health workers are most often prescribed to take "Kurantil", reviews of which characterize this medication as a fairly good angioprotector and vasodilator (a substance that stimulates the relaxation of smooth muscles in the walls of blood vessels).

Component composition and pharmacodynamics

The main active ingredient of "Kurantil" is dipyridamole. The auxiliary components are corn starch, lactose monohydrate, magnesium stearate, gelatin and white talc. Dipyridamole promotes the expansion of arterioles (small arteries immediately preceding the capillaries) in the coronary blood flow system. And when using large dosages of the drug - and in other places of the circulatory system. Large vessels of the coronary system under the influence of "Kurantil" do not undergo any changes, which distinguishes the drug from organic nitrates and calcium antagonists.

After taking the drug in the blood, the concentration of adenosine increases and vasodilation increases due to its presence. If you increase the dose of the drug "Kurantil" (instruction, reviews confirm this possibility), then inhibition of platelet aggregation (gluing) will be observed, which in itself reduces the risk of developing thrombus-forming processes.

In addition, dipyridamole can be called an interferon inducer, modulating the functioning of the interferon system. In this regard, under the influence of "Kurantil" nonspecific resistance of the body to viral infections increases.

Indications for admission

For the drug "Kurantil" instructions for use (reviews confirm the declared effectiveness) describes a fairly wide scope of influence on the human body. Taking the medication is indicated for the prevention and treatment of deviations in the system. cerebral circulation according to the type of ischemia, with discirculatory encephalopathy. Against the background of intolerance to aspirin, "Kurantil" will be very effective for primary and secondary prevention of coronary artery disease. Also, health workers often prescribe a drug for admission with an existing risk of developing venous and arterial thrombosis and for treating their complications. After surgical interventions for prosthetic heart valves, "Kurantil" minimizes the risk of developing thromboembolism.

"Kurantil" when planning pregnancy (reviews of patients confirming this) is often prescribed as a preventive measure to reduce the risk of developing placental insufficiency. as a component complex treatment, the medication is often used for deviations in blood microcirculation. As an immunomodulator and a substance that stimulates the induction of interferon, "Kurantil" can be prescribed for the prevention and treatment of respiratory viral infections, influenza.

Who should not take Curantil

Like absolutely any medication, "Kurantil" is contraindicated in people with individual hypersensitivity or intolerance to the main and auxiliary components. The drug is not prescribed for functional insufficiency of the activity of the kidneys and the heart muscle in the terminal stages (increasing oxygen starvation of all tissues of the body, the brain in the first place), acidosis (shift of the acid-base balance towards increasing acidity) and poisoning by metabolic products.

Further, "Kurantil" reviews of doctors are forbidden to be taken with reduced level blood pressure and coronary heart disease (ischemic heart disease) in the acute stage. It is unacceptable to take medication with the development of bleeding that has arisen for unknown reasons. As a result, you can not take "Kurantil" for people suffering from diseases that lead to the development of bleeding.

Curantil is used very carefully during pregnancy - the reviews are both positive and negative.

Possible side effects

Like any complex and highly effective medicinal product, "Kurantil" has a number of side effects to different organs and systems of the body. On the part of the cardiovascular system, it is possible to develop tachycardia (increased heart rate, especially with the simultaneous use of other vasodilators), bradycardia, unstable angina, increased bleeding during or after various surgical interventions. People who took the medication also report a decrease in their total blood pressure. In rare cases, myocardial infarction may develop.

The respiratory organs may respond by developing bronchial asthma. On the part of the hematopoietic system, there may be a decrease in the number of platelets, a change in their functional properties, and the development of thrombocytopenia is possible. In addition, when using the "Kurantil" remedy, patient reviews speak of occasional muscle pains.

Certain side effects and from the side of the central nervous system and its peripheral departments. There is a possibility of general weakness, headaches, dizziness. The gastrointestinal tract can manifest itself as a violation in the processes of digestion (pain in the epigastrium, nausea, vomiting, diarrhea).

Before you start using the drug "Kurantil" (reviews when planning treatment with this drug should be taken into account), it must be borne in mind that the reaction hypersensitivity to medicine can manifest itself in the development of various dermatitis, urticaria, skin rashes. Sometimes patients talk about a feeling of stuffy ears, rhinitis, myalgia.

Application: mode and dosing

The standard dosage for patients over 12 years of age is no more than 225 mg (can be divided into 3-6 doses during the day). However, most often the dosage is selected by the attending doctor, based on the severity of the patient's condition and depending on his individual response to the medication.

If a person suffers from coronary heart disease, he is prescribed a dose of 75 mg three times a day. If necessary, the daily volume of the drug may be increased by the attending physician. For the treatment of various abnormalities in the cerebral circulatory system (including for preventive purposes), the total dose per day can reach up to 450 mg (tablets of 75 mg, the number of doses is from 3 to 6).

In order to reduce the aggregation (gluing) of platelets, "Kurantil" is prescribed in a dosage of 75 to 225 mg during the day. In the most severe situations, the daily volume of the drug, as directed by the doctor, may increase to 600 mg.

During periods of spring and autumn epidemics of influenza and SARS, doctors usually prescribe 50 mg of the drug per day at a time (2 tablets of Curantil No. 25 or 2 tablets of Curantil 25). Standard duration treatment - 4-5 weeks.

For patients with frequent illnesses colds, with the prophylactic purpose "Kurantil" (analogues are recommended to be taken in accordance with the instructions) are prescribed 100 mg throughout the day (2 tablets or pills twice a day with a 2-hour time interval between doses). The course of treatment can last from 8 to 10 weeks.

As for pregnant women, "Kurantil" (application, reviews of gynecologists and recommendations of instructions for this is a direct confirmation of this) should be taken exclusively as directed by the doctor in charge of the pregnancy. Dosage - 1 tablet on an empty stomach, 1 hour before meals. It is necessary to strictly adhere to the regimen for taking "Curantyl", which was chosen by the doctor. If any alarming symptoms appear, you should immediately seek the advice of a gynecologist.

It is optimal to take tablets or dragees before meals, without breaking or chewing. It is necessary to drink the drug with a small amount of liquid.

Overdose: symptoms, treatment

The cardiovascular and nervous systems react most quickly to exceeding the permissible dose of "Curantyl". On the part of the heart and blood vessels, there is a decrease in total blood pressure, tachycardia (increased heart rate), redness of the skin and the appearance of a feeling of heat in the body. The central nervous system and its peripheral departments react with the development of general weakness and dizziness.

At present, no antidote has been identified. For the fastest elimination of the most severe symptoms, it is recommended to stop taking the medication. Next is assigned intravenous administration the drug "Aminophylline" in a volume of up to 100 mg. If an attack of angina develops (or any other reaction of the heart), the use of "Nitroglycerin" is prescribed - 1 tablet under the tongue.

In addition, symptomatic treatment is carried out in accordance with the severity of the patient's condition. Hemodialysis with an overdose of the drug "Kurantil" (medical reviews confirm) will not give a positive effect.

Interaction with other drugs

With the combined use of "Kurantil" with aspirin and anticoagulants, the antithrombotic effect of the latter is significantly enhanced and in some cases can lead to hemorrhagic complications.

With the simultaneous use of medicines for hypertension and "Curantyl", the effect of the former is enhanced. Drugs that are derivatives of Xanthine, as well as Theophylline, Caffeine, weaken the vasodilating effect of Curantil.

Tea or coffee can reduce the effectiveness of the drug. This fact must be borne in mind when treating with Curantil.

"Kurantil" and pregnancy: arguments "for"

As you know, during the bearing of a baby, all the organs and systems of a woman work with an increased load. Taking "Kurantil" during pregnancy, reviews, instructions for use report a beneficial effect of the drug on the process of fetal development. Since the arsenal of the drug reduces the risk of developing blood clots, strengthening vascular walls, improving blood microcirculation (reducing platelet aggregation), he ("Kurantil") is able to save the expectant mother from the mass of unpleasant problems that often accompany a pregnant woman. We are talking about edema, the development of hypertension, the appearance of frequent headaches, convulsions, "failure" of the kidneys after childbirth.

Also, "Kurantil" is often prescribed for the prevention and treatment of abnormalities in the cerebral circulation system. Another "for" - the ability of the drug to recover immune system and stimulating the production of interferon, increasing its activity. Indeed, during pregnancy, influenza and other seasonal viral diseases can lead to tragic consequences for the fetus.

In addition to all of the above, the "Curantil" tablets are regulated by gynecologists as safe for the fetus, without any effect on it. Whereas the drug has only a beneficial effect on the placenta. Moreover, according to medical specialists, "Kurantil" practically does not accumulate and does not linger in the body - it decomposes in the liver and is excreted in the bile. The drug has a positive effect on the normalization of placental blood flow, the violation of which leads to the fact that the developing child cannot receive the nutrients he needs from the mother's body in sufficient quantities.

Quite often, "Curantil" (medical reviews confirm the effectiveness) is prescribed for later dates pregnancy in cases where the condition develops premature aging placenta. In addition, it is often prescribed to women who are at risk of miscarriage or in complicated pregnancies.

Arguments "against" during pregnancy

The first thing worth mentioning is that "Kurantil" has a decent list of contraindications and possible side effects. Often, doctors recommend taking "Kurantil" when planning a pregnancy. Patient reviews are not always positive. The likelihood of developing a variety of allergic manifestations large enough, so you need to carefully approach the selection of dosage.

There have been very few clinical studies of this medicinal product. But the drug is not suitable for everyone, everything is very individual. If you think about it (which is typical of anxious future mothers), "Kurantil" during pregnancy is prescribed to prevent various kinds of disorders and deviations. But pregnancy is not a disease, it is not necessary to treat this condition.

In addition, it will be useful to know that in the last trimester, shortly before childbirth, it is better to cancel the use of "Kurantil" for the reason that it thins the blood. And in the process of delivery, various unforeseen situations and bleeding can occur, which can be definitely dangerous for a woman.

The opinion of patients about "Kurantil"

The opinions of people who took "Kurantil" both in connection with various diseases and during pregnancy are both positive (the majority of such reviews) and negative.

Patients who took the drug for violations of cerebral circulation speak well of the drug. And headaches practically go away, and dizziness, and feelings of constant general weakness cease to bother. Also positive for the most part on "Kurantil" reviews of pregnant women. A woman's body working in the mode of large overloads must be provided in full with a developing child with oxygen and nutrients. And if there are problems with the vessels of the brain, heart, with blood microcirculation - this medication will come in handy.

However, negative opinions about the medication also take place. It cannot be said that side effects develop very often, but they are. For example, when taking the drug "Kurantil", reviews of pregnant women report problems such as headaches, lowering blood pressure. Not so uncommon is the development of allergic reactions in the form skin rashes and itching.

In general, everything is strictly individual. Someone "Kurantil" helped get rid of problems, someone caused unwanted effects. In any case, consulting a doctor and strictly following his instructions will minimize the development of side effects and help achieve a positive effect in the treatment of this drug.

Curantil is a drug that is used to normalize blood circulation and restore the immune system. It is produced in the form of coated tablets (Kurantil N25 and N75) and dragees (Kurantil 25).

Pharmacological action Curantyl

In accordance with the instructions for Curantil, the active ingredient in the drug of all forms of release is dipyridamole. The excipients that make up Curantil 25 dragee are lactose monohydrate, gelatin, potato starch, magnesium stearate, sucrose, talc, calcium carbonate, macrogol 6000, light basic magnesium carbonate, glucose syrup, carnauba wax, titanium dioxide, polyvidone K 25, dye. Auxiliary components of Curantil tablets are corn starch, lactose monohydrate, sodium carboxymethyl starch (type A), gelatin, magnesium stearate, anhydrous colloidal silicon dioxide. The composition of the film shell includes talc, hypromellose, macrogol 6000, dye, titanium dioxide, simethicone emulsion.

When applied, Curantil promotes the expansion of coronary vessels, an increase in the volumetric blood flow rate, an increase in the oxygen content in the venous blood of the coronary sinus and its absorption by the myocardium.

The instructions for Curantil noted that the substance activates collateral coronary circulation, reduces the manifestations of acute hepatic-renal syndrome, has an angioprotective effect, and improves the process of microcirculation. The properties of the drug are due to an increase in the activity of endogenous adenosine due to a decrease in its uptake by tissues and destruction.

Curantil is an antagonist of the endogenous adenosine diphosphate aggregant, inhibits phosphodiesterase, due to which the release of aggregation activators from platelets (serotonin, thromboxane, adenosine diphosphate) is blunted and platelet aggregation is eliminated.

The use of Curantyl as an antiplatelet drug in combination with acetylsalicylic acid is effective. In a dose-dependent manner, the drug prolongs the pathologically shortened lifespan of platelets.

Curantyl dilates the coronary arteries, causing the phenomenon of intercoronary steal. The drug has a modulating effect on the interferon system and increases the body's antiviral resistance to viral infections.

The drug improves venous outflow, reduces the incidence of thrombosis in postoperative period, normalizes the process of microcirculation in the renal glomeruli and the retina of the eyes. Curantyl is effectively used to treat cerebrovascular disorders and reduce the tone of cerebral vessels.

During pregnancy, Curantyl prevents blockage of blood vessels in the placenta, thereby preventing the occurrence of fetal hypoxia.

Indications for use Curantyl

In accordance with the instructions for Curantil, the drug is prescribed to people for the treatment of dyscirculatory encephalopathy, ischemic cerebrovascular disorders. Recommended medication for the prevention and treatment of influenza and acute respiratory viral diseases.

Effective use of Curantyl in the composition complex therapy with microcirculation disorders of various etiologies.

In reviews of Curantyl, the effectiveness of taking the medicine for prevention is reported. coronary disease heart, venous and arterial thrombosis, thromboembolism after heart valve replacement surgery.

Method of application and dosage

The dosage of Curantyl is prescribed by the attending physician individually for each patient, depending on the severity of the disease.

In order to prevent and treat circulatory disorders of the brain, 75 mg of the drug is prescribed 3-6 times a day. The maximum daily dose should not exceed 450 mg.

To reduce platelet aggregation, 75-225 mg of Curantyl should be taken per day in several doses. In severe condition of the patient, the daily dose may be increased to 600 mg.

For the treatment and prevention of acute respiratory viral diseases and influenza, Curantyl 25 and N25 are prescribed 2 tablets / tablets 1 time per week. The duration of therapy is 4-5 weeks. In order to prevent the occurrence of relapses of viral diseases, it is recommended to take Curantyl 25 and N25, 2 tablets / tablets twice a day. The medicine should be taken once a week for 8-10 weeks.

During pregnancy, Curantyl is prescribed 75 mg 1 time per day or 25 mg 3 times a day.

Tablets and dragees should be taken whole in the morning on an empty stomach with a small amount of water.

Side effects of Curantyl

In reviews of Curantyl, it is reported that the drug can cause adverse reactions from the body systems:

• Cardiovascular: tachycardia, palpitations, coronary steal syndrome, bradycardia, flushing and flushing of the skin of the face, lowering blood pressure;
• Digestion: nausea, diarrhea, vomiting, abdominal pain;
• Blood coagulation: changes in platelet function, thrombocytopenia, rarely - bleeding during and after surgery;
• Central nervous system: headaches, noise in the head, dizziness.

In accordance with the reviews, Curantyl can stimulate the development of rhinitis, myalgia, arthritis, and the appearance of allergic rashes.

As a rule, the manifestation of side effects is blunted with prolonged use of Curantyl.

Contraindications

Contraindications to Curantil are:

• Hypersensitivity to the components of the drug;
• Diseases accompanied by a risk of bleeding;
• peptic ulcer and duodenum;
• Hemorrhagic diathesis;
• Hepatic and kidney failure;
• Violations heart rate;
• Arterial hypertension;
• Collapse;
• arterial hypotension;
• heart failure;
• subaortic stenosis;
• Stenosing widespread atherosclerosis coronary arteries;
• Unstable angina;
• Acute myocardial infarction;
• Children's age up to 12 years.

Overdose

In the reviews of Curantyl, it was noted that with an overdose of the drug, a decrease in blood pressure, tachycardia, angina pectoris, hot flashes, dizziness and weakness can be observed.

Additional Information

During pregnancy, Curantyl should be taken only under the supervision of a physician.

During drug therapy, you should refrain from driving vehicles and heavy machinery.

The instructions for Curantyl indicate that it is necessary to store the drug in a dark, dry place and out of the reach of children.

Shelf life - 4 years.

From drugstores it is released under the prescription of the doctor.

Pharmacodynamics. Curantyl - antiplatelet agent inhibits the reverse penetration of adenosine into the intracellular space, thereby increasing its concentration in blood plasma and antiaggregatory effect on platelets and erythrocytes. In addition, Curantil increases the antiplatelet activity of prostaglandin E1 and, in high doses, inhibits PDE in platelets, as a result of which cAMP accumulates in them and the release of thromboxane A2 from them is inhibited, which leads to inhibition of platelet aggregation and an increase in their life expectancy. Due to the adenosine mechanism, the drug also dilates the coronary arteries, increases coronary blood flow and stimulates the formation of collaterals.
Pharmacokinetics. After oral administration, it is rapidly absorbed in the gastrointestinal tract, mainly in the stomach and partly in small intestine. Absorption is highly pH dependent gastric juice, therefore, bioavailability has significant individual fluctuations and is 43±13%. About 98% binds to plasma proteins and accumulates in the heart and red blood cells. Cmax in blood plasma is observed approximately 60 minutes after oral administration. Dipyridamole is metabolized in the liver by binding to glucuronic acid. T1 / 2 is 20-30 minutes. Excretion of the drug occurs mainly with bile and feces in the form of monoclucuronide.

Indications for use of the drug Curantil

Stable angina pectoris, chronic heart failure, prevention and treatment of myocardial infarction, prevention and treatment of ischemic cerebrovascular accidents, chronic cerebrovascular insufficiency, dyscirculatory encephalopathy, vascular insufficiency, prevention of the formation of arterial and venous blood clots and thromboembolic complications (in combination with acetylsalicylic acid or with anticoagulants), prevention of thromboembolism after prosthetic heart valves, prevention of placental insufficiency, intermittent claudication, as part of complex therapy for microcirculation disorders various genesis.

The use of the drug Curantil

Therapy should begin with a gradual increase in dose. The duration of treatment and the dose are set individually depending on the indications and tolerability. Curantyl can be used for a long course of treatment. Dragee is taken without chewing, washed down with liquid, on an empty stomach or 1 hour before a meal.
Adults and children over the age of 12: 75-225 mg of dipyridamole per day (3-9 tablets) in divided doses. With a mild course of the disease or with an improvement in the condition, it is possible to take 25-50 mg 3 times a day. In severe cases of the disease, the dose may be increased to 600 mg of dipyridamole per day. To prevent thromboembolism in patients who simultaneously use anticoagulants or acetylsalicylic acid, the drug is prescribed 75 mg 3-6 times a day.

Contraindications to the use of the drug Curantil

Hypersensitivity to dipyridamole, diffuse stenosing atherosclerosis of the coronary arteries, subaortic stenosis, unstable angina pectoris, acute myocardial infarction, decompensated heart failure, severe arterial hypotension, collapse, cardiac arrhythmias, severe renal failure, diseases with an increased risk of bleeding ( peptic ulcer stomach and duodenum, hemorrhagic diathesis).

Side effects of Curantil

Usually mild and transient:
from the side of the cardiovascular system: headache and dizziness of vascular origin, arterial hypotension, flushing of the skin with a feeling of heat, tachycardia, especially with the use of vasodilators, sometimes exacerbation of coronary artery disease, with abrupt discontinuation of the drug, unstable angina pectoris or myocardial infarction may develop;
from the gastrointestinal tract: nausea, vomiting, diarrhea, dyspeptic disorders;
from the hepatobiliary system: there are reports that dipyridamole is a constituent of gallbladder stones;
from the skin and subcutaneous tissue: skin rash and urticaria;
from the immune system: possible bronchospasm and Quincke's edema;
from the blood system and lymphatic system: very rarely - increased bleeding during or after surgical interventions, in some cases - thrombocytopenia.
from the musculoskeletal system: myalgia;
general violations: general weakness.

Special instructions for the use of the drug Curantil

With a deficiency of lactase, galactosemia and malabsorption of glucose / galactose, the drug should not be used.
Use during pregnancy and lactation. The use of Curantyl is possible only after assessing the possible risk and expected benefits.
Application in children. The use of dipyridamole in children under 12 years of age is not recommended due to insufficient clinical experience.
The ability to influence the reaction rate when driving vehicles or working with machinery. A decrease in blood pressure is possible, and the resulting lack of blood supply to the brain can affect the ability to drive vehicles and work with potentially dangerous mechanisms.

Interactions of the drug Curantil

Xanthine derivatives (caffeine, theophylline) can weaken or completely neutralize the effect of the drug, so they should not be administered simultaneously. During treatment with Curantil, you should refrain from frequent use of strong coffee or tea. Under the influence of the drug, the effect of antihypertensive drugs may increase, as well as the anticholinergic activity of distigmine may decrease. Curantil can enhance the effect of anticoagulants and acetylsalicylic acid, therefore, with their simultaneous use, it is necessary to take into account possible increase the risk of intolerance to these funds.

Overdose of the drug Curantil, symptoms and treatment

Symptoms: general vasodilation, accompanied by hypotension, tachycardia, a feeling of warmth in the body, flushing of the skin of the face, weakness and dizziness.
Treatment: it is necessary to wash the stomach or induce vomiting; take measures to reduce absorption, prescribe adsorbents and other symptomatic therapy. The vasodilatory effect of dipyridamole can be stopped by intravenous administration of aminophylline (50-100 mg for 1 min). To stop an attack of angina pectoris, nitroglycerin is used sublingually.

Storage conditions of the drug Curantil

In a dark place at a temperature not exceeding 25 ° C.

List of pharmacies where you can buy Curantil:

• St. Petersburg

Curantyl has a beneficial effect on circulatory system: thins the blood, improves its circulation, dilates blood vessels. This drug is often prescribed during pregnancy: it will help save the life of the baby if a woman has placental insufficiency.

Why is Curantyl prescribed to pregnant women?

Curantyl belongs to the group of antiaggregants. These medications prevent platelets from sticking together, increase their lifespan.

Prevention of placental insufficiency- this is the main reason for prescribing Curantyl to pregnant women. With this disease, the placenta (a special organ that connects the fetus to the mother's body) ceases to perform its functions: it does not supply the embryo with oxygen and does not nourish it.

The drug improves blood circulation and eliminates the lack of oxygen (hypoxia) in the tissues of the fetus. It also prevents intrauterine growth retardation and negative changes in the placenta (for example, its detachment).

Curantyl is safe for the baby, since it only affects the blood vessels of the placenta, which serves as a barrier that does not allow drugs and infections to pass to the developing fetus.

This remedy also benefits the pregnant woman herself. It thins the blood, preventing the formation of blood clots. Improves blood microcirculation, preventing varicose veins and hemorrhoids. Helps to lower blood pressure, improve kidney function and strengthen blood vessels.

Besides, active substance(dipyridamole) stimulates the formation of interferons that fight viruses. Therefore, the medicine strengthens the immune system, reducing the risk of contracting influenza and SARS.

The drug is used to prevent high blood pressure, seizures, late toxicosis and edema.

In women with hypotension, an even greater decrease in pressure is possible.

If there is an urgent need to take this drug, then the discomfort caused by the drug and the benefit for the baby should be compared. This will help you decide if Curantyl is right for you or if you should look for an alternative.

Every woman should ask the gynecologist for what reason she takes Curantyl. There are several reasons:

• prevention or treatment of impaired blood circulation in the placenta;
• fetal hypoxia;
• an increase in the number of platelets, diagnosed by a blood test;
• protection against seasonal diseases (ARVI, acute respiratory infections, influenza);
• increased blood clotting;
• insufficient blood circulation in the capillaries;
• arterial hypertension (high blood pressure);
• prevention of thrombosis in varicose veins.

For the justified use of this drug, there must be information proving the development of one of the diseases in the future. healthy woman with a normal pregnancy, it makes no sense to drink Curantil.

The use of the drug in early pregnancy

Usually, pregnant women are prescribed Curantyl for several courses with a break in taking it for a while, but sometimes expectant mothers drink it during the entire period of bearing a child.

The drug for early dates prevents fetoplacental insufficiency, normalizing blood circulation between mother and fetus. Thanks to a good blood supply, the embryo receives enough food and oxygen.

In order to avoid bleeding in the first trimester, the doctor must select the dosage, taking into account the individual health indicators of the ward.

To reduce the risk of bleeding when taking Curantyl in the early stages, exclude blood-thinning foods from the diet. The main ones are listed below.

1. Vegetables: onions, tomatoes, Bell pepper, garlic, sauerkraut, pickles.
2. Fruits: citrus fruits (lemon, grapefruit, orange), apples.
3. Berries: strawberries, strawberries, currants, raspberries, viburnum, blueberries, cranberries, cherries.
4. Natural freshly squeezed juices, vegetable oils.
5. Fish, fish oil.

Or, if the drug is poorly tolerated, replace the use of Curantyl with these products, unless, of course, the doctor approves such an alternative, which is possible only in case of a slight deterioration in the course of pregnancy.

The use of the drug in late pregnancy

Often, Curantyl is prescribed in the third trimester for late toxicosis (gestosis of pregnant women). Thick blood leads to circulatory disorders throughout the body of a woman. The blood flow in the capillaries is disrupted, therefore internal organs cease to receive a sufficient amount of substances and oxygen, there is a failure in their work. As a result, the fluid is retained in the tissues, there is a strong swelling of the body of the pregnant woman (legs, arms, abdomen and face).

Also, the use of this drug in the last months of pregnancy helps the development of the child. For example, at the 34th week of pregnancy, there are significant processes in the development of the child's brain, at the 35th week - a layer of subcutaneous fat and lungs, and full blood flow contributes to the formation of brain cells, lungs and other important organs. At these times, the baby is developing rapidly, and he just needs his mommy to feel good.

At 37-38 weeks of pregnancy, taking Curantyl will be necessary to normalize the well-being of the expectant mother. Prenatal swelling usually sets in before the finish line, and Curantil copes well with it.

Two weeks before the expected date of birth of the baby, it is necessary to stop drinking Curantyl in order to avoid large blood loss during childbirth.

How to take Curantyl during pregnancy? And at what dosage?

When calculating the required dosage of Curantyl, the gynecologist takes into account many factors: the duration of pregnancy, the reasons for the appointment, test results, and so on. Therefore, without consulting a doctor, you should not drink pills: you can harm yourself and your baby.

Usually they drink 1 tablet (25 mg) three times a day, but sometimes high doses of 75 mg are prescribed for pregnant women.

They must be taken on an empty stomach or one hour before meals or 1.5-2 hours after it. It is desirable to drink Curantyl tablets at the same time, drinking plenty of water. They should not be chewed or bitten.

If the condition does not improve, then do not increase the dosage yourself. Tell your doctor about this, otherwise self-increasing the dose may cause side effects.

Contraindications to the use of the drug

Curantyl is contraindicated for pregnant women with the following diseases:

• arterial hypotension (reduced arterial pressure): the drug dilates blood vessels and lowers blood pressure even more;
• liver failure: dipyridamole is converted in the liver, so Curantyl should not be taken if there are problems with the liver;
• heart failure: the active substance (dipyridamole) accumulates in the heart;
• diseases that increase the risk of bleeding (stomach and / or intestinal ulcers): Curantil thins the blood, so large blood loss is possible;
• chronic renal failure: part of dipyridamole is excreted in the urine;
• hypersensitivity to the components: an allergic reaction may develop.

The main constituent of the drug is able to accumulate in red blood cells, which are carried with blood throughout the body. As a result, all weakened organs can suffer.

Side effects and drug interactions

Instructions for use reports such possible side effects of the drug: nausea, diarrhea, dizziness, headache, tachycardia ( cardiopalmus) or, conversely, bradycardia (slow heartbeat), a rush of blood to the face, decreased pressure, skin rash.

If you experience nausea, dizziness and headache at the beginning of taking Curantyl, do not worry, everything will pass soon. These symptoms appear due to a decrease in pressure, and usually stop after a while. But the rash indicates allergic reaction, in this case, you must stop drinking the medicine and consult a doctor.

It is worth noting that it is not recommended to drink tea or coffee at the same time (since these drinks contain xanthine derivatives) and Curantyl. After all, then the vasodilating effect of the latter may decrease.

Aspirin is contraindicated for use during pregnancy, and its combination with Curantyl is generally prohibited.

Curantyl is able to enhance the effect of drugs that lower high blood pressure. Therefore, in order to avoid a sharp drop in pressure, Curantyl should not be taken simultaneously with antihypertensive drugs.

Curantyl when planning pregnancy

A woman can take care of the baby and prepare her body for pregnancy, and on the advice of a doctor, start taking Curantyl 3 months before the planned conception. Thanks to this drug, the uterus builds up a special layer - the endometrium, which is necessary for the normal attachment of a fertilized egg to the uterine wall.

This remedy is also prescribed in cases where a woman has previously had miscarriages, as well as in the case of artificial insemination. Curantyl, along with other drugs, is also taken for diseases of the uterus, for example, endometriosis and myoma.

The use of Curantyl when planning pregnancy will prevent thrombophilia, which will protect the fetus from the formation of blood clots in the placenta.

Curantyl at correct use safe for pregnant women. Only your gynecologist can prescribe it. Do not neglect the advice of a doctor: the drug will prevent late toxicosis and placental insufficiency - diseases that life threatening baby and maternal health.

"Kurantil" is a drug widely used in cardiological, obstetric and therapeutic practice. The tool has a combined effect, which allows it to be used for the treatment of pathologies and complications of various origins.

Most often, "Curantil" is prescribed to pregnant women with manifestations of toxicosis of the second and third degree, as well as violations in the formation or functioning of the placenta.

Pharmacological action of the drug

"Kurantil" has a pronounced therapeutic effect, starting from 3-4 days of use. Therapeutic effect achieved through pharmacological properties drugs, including:

• expansion of blood vessels, improvement of blood circulation;
• decreased platelet aggregation;
• increased activity human interferon;
• increased resistance to viruses;
• immunomodulatory action.

When is it appointed?

"Kurantil" is rarely used as the main component of therapy - most often the drug is included in the combined treatment regimen for diseases of various origins. Diagnoses and pathologies in which it is advisable to prescribe the drug are indicated in the official instructions.

In cardiology:

• violation of the processes of blood circulation of the brain;
• encephalopathy (damage to certain parts of the brain) of the discirculatory type;
• thrombosis of veins and arteries (treatment and prevention);
• prosthetic heart valves rehabilitation period after surgery to prevent thromboembolism).

In obstetrics/gynecology:

• placental insufficiency;
• other pathologies of the placenta, accompanied by circulatory disorders;
• hypoxia resulting from a lack of oxygen molecules due to impaired blood microcirculation in the vessels of the placenta.

In general (family) therapy:

• viral infections(influenza, SARS, etc.);
• decreased immunity;
• recovery period after surgical intervention(as an immunomodulator).

How to use?

Tablets and dragee "Kurantil" should be swallowed whole. Drink liquid without caffeine and sugar. The dosage of the drug is selected by the attending physician, taking into account tolerability, diagnosis and concomitant chronic diseases.

Note! For maximum effectiveness, the drug should be taken on an empty stomach.

Contraindications

The list of restrictions for the appointment of "Curantyl" is quite impressive, therefore, the independent use of this drug is strictly prohibited. The use of "Kurantil" is contraindicated in the following diagnoses / conditions:

• heart failure in the stage of decompensation (dysfunction);
• collapse;
• violation of the heart rhythm;
• myocardial infarction ( acute stage);
• exacerbation of stomach / duodenal ulcers;
• diathesis of hemorrhagic type;
• atherosclerosis of the coronary arteries;
• subaortic stenosis of the aorta;
• high or low blood pressure;
• angina pectoris (in the absence of stability).

Also, the drug is not prescribed for children under 12 years of age and patients with severe forms kidney and liver failure.

Cases of overdose have not been recorded to date.

Application during pregnancy

"Kurantil" is one of the commonly prescribed drugs during pregnancy. It is prescribed by an observing gynecologist or obstetrician to normalize the condition of the fetus with various disorders in the functioning of the child's place (placenta). The placenta consists of a huge number of small blood vessels and capillaries through which nutrients are transported. Vitamins and oxygen to the fetus.

When failures occur in the circulatory system, the fetus does not receive useful elements and oxygen molecules, which can affect its growth and development. The drug of choice for the normalization of the placenta is "Kurantil" (as the safest and most effective drug).

Remember that you can not prescribe the drug yourself.

Application for lactation

The use of "Kurantil" is not contraindicated when breastfeeding with the permission of the attending physician who assessed the ratio of possible risks and benefits for a woman's health.

Side effects

Tolerability of the drug is generally very good, but side effects have still been diagnosed. Most often, patients complain of digestive disorders, epigastric pain, cardiac disorders, and skin reactions.

This is manifested by the following signs:

• nausea;
• diarrhea;
• headaches (possibly dizziness);
• myalgia;
• redness of the face;
• increased heart rate;
• allergy (in the form of skin manifestations).

Important! When prescribing to patients with unstable pressure, the hypotensive effect of "Kurantil" should be taken into account.

Composition and form of release

The main component of the drug, which has angioprotective and immunomodulatory effects, is dipyridamole. Depending on the content of the main component, the drug is produced in three dosage forms:

• dragee containing 25 mg of dipyridamole (100 pieces in a pack);
• coated tablets containing 25 mg of dipyridamole (120 pieces per pack);
• coated tablets containing 75 mg of dipyridamole (40 pieces per pack).

Pharmacokinetics

The main part of dipyridamole is absorbed from the stomach (the minimum amount is absorbed from the large intestine). "Kurantil" perfectly binds to plasma proteins (by 98%), is metabolized in the liver. The maximum concentration reaches 60 minutes after ingestion, accumulating mainly in erythrocytes and heart muscle.

special instructions

At the time of treatment with Curantil, any drinks containing caffeine (tea, cocoa, coffee, etc.) should be excluded from the diet, as they significantly reduce the effectiveness of the therapy.