Okumetil (eye drops): instructions, reviews, price, analogues. Eye drops ocumet Blue eye drops

Country of origin

Product group

combination drug for local application

Release forms

• 10 ml in plastic dropper bottles of blue-violet color with the control of the first opening. 1 bottle, together with instructions for use, is placed in a cardboard box.

Description of the dosage form

• Eye drops

pharmachologic effect

Pharmacokinetics

Special conditions

Okumetil indications for use

• chronic nonspecific conjunctivitis and blepharoconjunctivitis; allergic conjunctivitis and blepharoconjunctivitis; angular conjunctivitis; reduction of symptoms of irritation of the tissues of the eye (redness, itching, sensation foreign body).

Okumetil contraindications

• hypersensitivity to the components of the drug; angle-closure glaucoma; dry eye syndrome; pregnancy; lactation; prostatic hyperplasia, stenosing gastric ulcer and duodenum, cervical stenosis Bladder; bronchial asthma; epilepsy, cardiovascular disease (CHD, arterial hypertension) pheochromocytoma hyperfunction thyroid gland diabetes mellitus severe atherosclerosis childhood up to 2 years.

Okumetil side effects

• After instillation, a slight burning sensation, blurred vision, and the development of allergic reactions may occur. With aphakia, the development of maculopathy and the appearance of a central scotoma are possible. In this case, the withdrawal of the drug leads to a regression of symptoms. After local use of naphazoline, which is part of Okumetil, reactive hyperemia and swelling of the mucous membrane of the eyes, pupil dilation, increased IOP (intraocular pressure) may occur. With prolonged use, the phenomenon of tissue irritation occurs most often. Since, when applied topically, naphazoline has a general resorptive effect, it is possible to develop tachycardia, increase blood pressure, nausea, headache. With topical application of diphenhydramine, side effects of both local and systemic nature may develop: accommodation paresis, photosensitivity, dryness and numbness of the mucous membrane of the eyes, drowsiness, weakness, decreased psychomotor reactions and impaired coordination of movements, dizziness. With prolonged use of zinc salts, dryness of the mucous membrane of the eyes may occur.

drug interaction

Storage conditions

• keep away from children

Okumetil eye drops are a combined drug with anti-allergic pharmacological action. They are prescribed for the treatment of various specific inflammatory reactions of the eyes in adults and children over 2 years of age. The use of the drug for pregnant and lactating women is excluded.

Dosage form

The eye drops are a clear blue liquid. It is in plastic dropper bottles of 5 and 10 ml.

Description and composition

The composition of the ophthalmic solution includes several active compounds (the content in 1 ml is indicated):

• Diphenhydramine hydrochloride - 10 mg.
• Zinc sulfate - 10 mg.
• Naphazoline hydrochloride - 10 mg.

Also, the composition of the drug includes the following auxiliary components:

• Lemon acid.
• Methylene blue dye.
• Hypromellose 4000.
• Sodium citrate.
• Sodium hydroxide.
• Benzalkonium chloride.
• Sodium chloride.
• Sterile distilled water.

Pharmacological group

Medication represents the pharmacological group of antihistamine antiallergic ophthalmic drugs. The pharmacological action of the drug is due to the presence of a combination active components:

• Naphazoline is a sympathomimetic compound that has a pronounced vasoconstrictor effect that develops quite quickly in tissues. At local application the result is a decrease in the severity of edema and hyperemia of the mucous membrane.
• Zinc sulfate - has a drying, astringent, antiseptic and anti-inflammatory pharmachologic effect on the mucous membrane with local application of the drug.
• Diphenhydramine is a compound blocker of H1-histamine receptors. It has an anti-allergic effect, as it suppresses the response of tissues to the effects of the main mediator of the inflammatory reaction of histamine. Due to this, it reduces swelling, reduces the permeability of the vessels of the microvasculature.

In general, the drug has an anti-inflammatory, anti-allergic and antiseptic therapeutic effect.

After instillation of the ophthalmic solution into the eyes, the active components undergo local adsorption in the tissues. They partially penetrate into the blood.

Indications for use

The medicine is prescribed for complex treatment specific inflammatory reactions in the structures of the eye, which are predominantly allergic in origin.

for adults

There are several main medical indications for which the drug is used:

• and blepharoconjunctivitis, which are of allergic origin.
• Reducing the severity of manifestations of irritation of the tissues of the eye, which include hyperemia (redness) of the conjunctiva, burning, sensation of a foreign body.
• Nonspecific and blepharoconjunctivitis, which have a chronic course.
• Angular.

for kids

The drug can be prescribed to children older than 2 years for the same medical reasons.

The drug is contraindicated.

Contraindications

A number of pathological and physiological conditions of the human body are distinguished, in which the use of a drug is contraindicated:

• Angle-closure glaucoma.
• Pregnancy at any stage of the course and lactation.
• An ulcer of the stomach or duodenum, which is accompanied by the development of stenosis.
• Bronchial asthma.
• Cardiovascular disease, including ischemic disease, arterial hypertension.
• Increased functional activity.
• Pronounced atherosclerosis of arterial vessels.
• Individual intolerance to the components of the drug.
• Dry eye syndrome.
• Prostate hyperplasia in men.
• Stenosis of the neck of the bladder.
• Epilepsy.
• Pheochromocytoma.
• Children's age less than 2 years.

Carefully medicine is used in patients who are taking monoamine oxidase (MAO) inhibitors, as well as any drugs that increase systemic blood pressure.

Applications and doses

Eye drops are instilled into the lower conjunctival sac. To do this, the lower eyelid is pulled back with a finger, the head is tilted back a little, and the ophthalmic solution is instilled with the other hand using a dropper bottle. In this case, it is important to ensure that the tip of the dropper does not touch the surface of the structures of the eye, as this can cause mechanical damage or infection of the structures.

for adults

The average recommended dose is 1 drop, which is instilled into the lower conjunctival sac 2-3 times a day. The duration of therapy is determined by the attending physician individually. If there is no improvement within 72 hours, then the drug should be discontinued and re-examined by a medical specialist.

for kids

The dosage has no significant differences, usually it is 1 drop in the conjunctival sac of the eye affected by the pathological process 2 times a day.

for pregnant women and during lactation

Medication is contraindicated for use.

Side effects

After the start of using the ophthalmic solution, the following local negative reactions may develop:

• "Blurring" vision.
• The appearance of a burning sensation, a feeling of "sand" in the eyes.
• Maculopathy if the patient has concomitant aphakia.
• Appearance of central scotoma.
• Edema of the mucous membrane of the eyes, hyperemia, dilated pupil, increased intraocular pressure, which are due to the presence of naphazoline in the preparation.
• Paresis of accommodation.

Somewhat less often, systemic side effects due to the absorption of the active components of the drug into the blood:

• Tachycardia.
• An increase in the level of systemic arterial pressure.
• Headache.
• Nausea.
• Drowsiness.
• Weakness.
• Decreased speed of psychomotor reactions.
• Dizziness.
• Violation of coordination of movements.

Interaction with other drugs

The active components of the ophthalmic solution, when used simultaneously, may interact with drugs of other pharmacological groups Therefore, before using the drug, it is important to consider the following features:

• Strengthening the therapeutic effect of MAO inhibitors, beta-blockers, adrenomimetics.
• Slowing down the adsorption of local anesthetics.
• Reducing the effects of diphenhydramine and stimulants of the activity of the central nervous system.
• Zinc sulfate, which is part of eye drops incompatible with salts of lead, silver, quinine, citral, ichthyol.

If it is necessary to simultaneously use several ophthalmic preparations, the period of time between the installation in the eye should be at least 15 minutes.

special instructions

Before using the ophthalmic solution, it is important to pay attention to several precautions:

• In order to avoid contamination of the solution and subsequent infection of the eye, it is important not to touch the tip of the dropper bottle with surrounding objects.
• The composition of the ophthalmic solution includes the preservative benzalkonium chloride, which has a negative effect on the condition of contact lenses. Before instillation of eye drops, it is recommended to remove them. Re-installation is allowed no earlier than after 15 minutes.
• Immediately after instillation of the eyes, "blurring" of vision is possible, therefore, potentially dangerous work can be performed no earlier than 15 minutes later.
• Activities that require sufficient concentration of attention and speed of psychomotor reactions should be careful, since against the background of the use of eye drops, their influence on the functional state of the structures of the central nervous system is not excluded.

Overdose

Cases of overdose with ophthalmic solution in clinical practice its uses have not been registered to date.

Storage conditions

The drug should be stored in intact primary packaging, in a dark, dry place inaccessible to children at an air temperature of +15 to +25 ° C. The shelf life is 3 years from the date of manufacture. After opening the dropper bottle, the solution can be used within 1 month.

Analogues

Montevisin

A drug that has a similar healing effect. It contains tetrizoline. The drug, when applied locally, has a vasoconstrictive effect and helps to reduce the severity of mucosal edema. The drug is presented in dosage form eye drops. It is used to treat inflammatory and allergic eye pathology in adults and children over 6 years of age. The medicine is contraindicated for pregnant and lactating women.

Eye drops that contain tetrizoline in their composition and have a decongestant therapeutic effect. They are designed to reduce the severity of manifestations of irritation, inflammatory processes and allergic eye reactions. The drug is intended for adults and children over 3 years of age. It is allowed to prescribe eye drops during pregnancy and breastfeeding if the intended benefit to the mother outweighs the potential risks to the fetus.

A drug that has a decongestant effect due to local vasoconstriction in the mucous membrane. It is available in the dosage form of eye drops and contains tetrizoline. The drug can be prescribed to adults and children over 2 years of age for the complex treatment of inflammatory and allergic eye pathology. Data on the possibility of using the drug during pregnancy and lactation are not provided.

Price

The cost of Okumetil averages 242 rubles. Prices range from 191 to 310 rubles.

Ophthalmic product made in Egypt Okumetil used in the treatment of eye diseases and other pathologies of the organs of vision.

The advantage of the drug over similar drugs is the possibility of treating young children.

It has many contraindications, a wide range of adverse reactions, so the use of Okumetil should be carried out with extreme caution.

Compound

The drug is based on three powerful substances:

• zinc sulfate - has astringent, drying, antiseptic, anti-inflammatory effect;
• diphenhydramine hydrochloride - is a blocker of antihistamine receptors, effective against swelling, irritation, refers to anti-allergic, anti-inflammatory, antiseptic substances;
• naphazoline hydrochloride - eliminates hyperemia and puffiness.

Produced in the form of drops, in a sterile plastic bottle with a pipette dispenser.

Indications for use

Used in therapy:

• non-specific;
• allergic conjunctivitis;
• blepharoconjunctivitis;
• angular conjunctivitis.

It is also used as a symptomatic therapy to eliminate irritation, itching, redness of the eyes, which are accompanied by third-party diseases.

Application restrictions

It is forbidden to use when:

• closed-angle;
• hyperplasia;
• pregnancy;
• breastfeeding;
• ulcerative lesions of the stomach;
• stenosis;
• asthma;
• epileptic seizures;
• hypertension;
• ischemia;
• pheochromocytoma;
• disorders in the thyroid gland;
• diabetes
• atherosclerosis of a pronounced form;
• hypersensitivity to the substances that make up the composition.

The use of the drug is prohibited for the treatment children up to two years of age. Administered with caution to patients old age and those taking medications to raise blood pressure.

Possible negative effects

Even short-term use of the drug can cause negative reactions.

Many patients complain of itching, burning, pain in the eyes immediately after instillation. However, these symptoms disappear after a couple of minutes.

In more rare cases, an allergic reaction to the medicinal components of the drug develops.

It is also possible that:

• puffiness;
• haze, blurred visibility;
• increased intraocular pressure;
• irritation;
• rapid heartbeat;
• nausea;
• vomiting;
• migraine.

In rare cases, the patient has a strong dilated pupils.

If adverse reactions occur after using the drug, you should consult with your doctor. It may be necessary to reduce the dosage or cancel the drug, followed by its replacement with a similar drug.

Instructions for use

Children from the age of two are prescribed the minimum dosage - drop by drop no more than 2 times a day.

From the age of eighteen, the dosage increases (2 drops up to 4 times a day).

The optimal duration of therapy is up to 10 days.

It is necessary to monitor the reaction of the body to medicinal product. If after 2-3 days there is no improvement in the condition and there is no positive dynamics in the treatment, it is necessary to notify the attending physician about this.

Recommendations for the use of the drug in the article are presented for general information, you should not take them as a guide to therapy. It must be remembered that the dosage and duration of treatment are selected by the doctor individually for each patient.

Price

Average price in pharmacies - 240 rubles(for 10 ml).

It belongs to potent drugs, has many restrictions for use, the likelihood of unwanted reactions is high, therefore it is sold only by prescription.

It is important to note that after opening the vial, you can use the drug within a month. After that, the drug must be disposed of.

Reviews

How effective and safe is the drug, what adverse reactions causes, patients say:

Vladimir, 42 years old, Krasnodar:

I want to warn patients against driving a car while using Okumetil. Perhaps this is just my reaction to the drops, but the sensations are not pleasant. The eyes began to itch, watery, after that the pupils also dilated. And noticed that one pupil expanded more than the other. And this strange effect lasted about two hours. The optical view was quite deformed, and from the side my eyes looked more than strange. Several times I instilled my eyes with Okumetil and each time there were similar adverse reactions.

However, I want to note that the tool is very effective, quickly relieves inflammation, swelling, redness.

Kristina, 25 years old, St. Petersburg:

I work at the office at the computer, because of this my eyes suffer a lot - they are constantly red, swollen, I feel severe discomfort. I consulted with an ophthalmologist who advised me to buy Okumetil.

I noticed a positive effect almost immediately. Now my eyes feel much more comfortable when working at the computer for a long time. Only sometimes when instilled I feel a burning sensation, which quickly passes.

Valentina, 37 years old, Petrozavodsk:

She caught conjunctivitis, and as prescribed by the doctor, she began to use Okumetil. After a couple of days, I began to notice improvements, on the third day suppuration disappeared. But the doctor advised me to take a full course - 10 days, in order to consolidate the result and completely recover from an unpleasant illness.

When using the drug, headache and tachycardia periodically occurred.

Doctors note that many patients complain of adverse reactions, so treatment must be carried out under the supervision of a specialist in order to adjust the dosage in time or replace Okumetil with a more gentle drug.

Analogues

Since Okumetil has an extensive list of contraindications, and in most patients it causes negative concomitant reactions, the doctor often has to select analogues.

The best similar drugs include:

Among the contraindications are glaucoma and individual intolerance to the drug. It can provoke the appearance of a headache, burning in the eyes, a jump in intraocular pressure. Compared to the original, the analogue has significantly fewer restrictions on use and in rare cases causes side effects.

You can buy Octilia for about 330 rubles .

Prolonged use of the drug can provoke the appearance of migraine, nausea, hyperglycemia, impaired heart rate, increased intraocular pressure.

Cost - approx. 170 rubles .

Compared with Okumetil, the analogue is cheaper in cost, has fewer restrictions on use, but is undesirable for long-term use, since it is dangerous for the development of adverse reactions (including a negative effect on the functioning of the heart muscle).

Treatment with Okumetil guarantees getting rid of ophthalmic diseases and other pathologies in a short time.

Requires careful use, as it can provoke the appearance of severe adverse reactions. Not suitable as a means for self-medication, it is sold only on prescription.

Video

How effective are Okumetil eye drops? Reviews about local preparation you can find at the end of the article. It will also provide information on the purpose for which the said medication is used, whether it has side effects and contraindications, what characteristics it has and what is included in its composition.

Description, packaging and composition

Okumetil drops, reviews of which are of a very different nature, contain the following active ingredients: zinc sulfate, naphazoline hydrochloride and diphenhydramine hydrochloride. Also, the medication in question includes such additional components as citric acid, sodium citrate, methylene blue dye, benzalkonium chloride, distilled water, sodium chloride, sodium hydroxide and hypromellose 4000.

Where and in what packaging can I buy Okumetil eye drops? Patient reviews report that this medication is sold in any pharmacies. It can also be ordered online.

According to the instructions, this drug goes on sale in the form of a clear solution. blue color in plastic dropper bottles of 5 and 10 ml.

Pharmacological action of the local agent

What are Okumetil drops? Reviews of doctors about the effectiveness of this remedy are presented below. And the instruction says that this drug is intended for topical use in ophthalmic diseases of various origins.

Thanks to the components that make up the drug, "Okumetil" helps to reduce swelling of the eyelids. This happens through vasoconstriction and blocking of histamine receptors.

Properties of the drug

When is it prescribed and what determines the effectiveness of Okumetil drops? Reviews of experts report that this drug is very often used for various eye diseases. It contributes to a good therapeutic result due to its combined composition.

When applied topically, zinc sulfate has not only an anti-inflammatory, but also an antiseptic effect. Diphenhydramine blocks H1-histamine receptors, preventing tissue swelling, reducing capillary permeability and eliminating pain.

According to its structure, naphazoline belongs to sympathomimetics. In this regard, its regular use in various ophthalmic diseases helps to reduce tissue swelling, as well as hyperemia of the mucous membrane.

Kinetic characteristics

Do Okumetil drops penetrate into the bloodstream, reviews of which are more positive? When used topically, this medication is absorbed fairly well. There is currently no other information on the kinetic properties of the mentioned drug, including the degree of its penetration into the tissues of the eyes.

Indications

What are Okumetil drops prescribed for? Reviews of experts say that this drug helps well with various ophthalmic diseases. Thus, it is often used for:

allergic conjunctivitis; chronic nonspecific conjunctivitis; blepharoconjunctivitis; angular conjunctivitis.

It should also be noted that the drug in question can be prescribed in order to reduce signs of irritation of the eye tissues, as well as to eliminate local redness, itching and foreign body sensation.

Contraindications

Do Okumetil drops have contraindications? Reviews of doctors say that, despite its apparent simplicity, this medication has a fairly large number of prohibitions for use. According to the instructions, contraindications to the use of this remedy are:

children's age up to two years; pregnancy; hypersensitivity to active and additional substances of the drug; lactation.

angle-closure glaucoma; bronchial asthma; epileptic seizures; pheochromocytoma; various diseases of the gastrointestinal tract; hypertension; "dry eye" syndrome; disruption of the thyroid gland; heart and vascular diseases; atherosclerosis; arterial hypertension; diabetes mellitus.

Mode of application

How are Okumetil drops used? Reviews of ophthalmologists indicate that this drug is intended for local use only.

In the absence of special prescriptions from a doctor, the medication is instilled one drop into each affected eye (conjunctival sac) three times a day.

If no improvement in symptoms is observed within 72 hours, then you should stop the drug yourself and consult an ophthalmologist.

Side effects

Most often, against the background of the use of Okumetil, patients experience a slight burning sensation of the eyes. There may also be various allergic reactions and short-term blurred vision.

In patients with "aphakic eye" (lack of the lens), the use of this drug may provoke the development of maculopathy and central scotoma. With the manifestation of such side effects, the drops are immediately canceled.

It should also be noted that the drug "Okumetil" can cause:

headache; reactive hyperemia; increased blood pressure; nausea; tachycardia; drowsiness; paresis of accommodation; photosensitivity; feeling of weakness; dryness and numbness of the mucous membrane; dizziness; impaired coordination of movements.

Does the drug "Okumetil" affect the patient's ability to drive vehicles? Reviews (it is undesirable to use lenses during treatment with this remedy) doctors do not provide any information on this matter. As for the instructions, she reports that within ¼ hour after the installation of the medication, the patient's visual acuity may decrease. In this regard, during the specified period of time, it is not recommended to drive a car and engage in dangerous species activities.

To avoid contamination of the solution, the vial should be kept tightly closed and avoid contact of its tip with any surface.

Analogues and cost

You can buy Okumetil eye drops for 120-150 rubles. If this drug is contraindicated for you, then it can be replaced (after consultation with an ophthalmologist) with such means as Vizin or Octilia.

Reviews

Patient reviews of Okumetil eye drops are very ambiguous. Most patients report that this drug copes with the task quite effectively. It very quickly eliminates all the symptoms of ophthalmic diseases, significantly alleviating the patient's condition.

However, another category of patients claims that Okumetil does not show any therapeutic effect. Moreover, sometimes it contributes to the appearance of allergic reactions, and also aggravates the already difficult condition of a person.

In connection with all of the above, doctors conclude that the drug in question has a different effect on different people. Therefore, it is not recommended to use it on your own. Before instillation of the medication, it is imperative to contact an ophthalmologist, who is obliged to full examination patient.

According to the instructions, Okumetil eye drops are an anti-allergic eye medication.

Helps in the fight against most ophthalmic diseases, removes eye fatigue, redness, swelling.

Some side effects may occur.

Instructions for use of Okumetil eye drops

How to use eye drops okumetil blue? Pharm. action: a combination of three components that make up it reduces swelling and other allergic reactions of the eyes, relieves inflammation, disinfects eyeball and surrounding tissues.

Composition according to the instructions for use:

Zinc sulfate (antiseptic, anti-inflammatory and astringent). Diphenhydramine. Due to the specific effect on certain receptors, it helps to reduce capillary permeability, prevent and relieve pathological edema. Nafazolin. Its function is to provide a quick and long-term vasoconstrictive effect. As a result, hyperemia and swelling of the eye mucous membranes decrease, increased vascular permeability is neutralized.

This component has proven to be effective remedy whitening protein. If we recall the first two "ingredients", then they only enhance the ability of naphazoline, whiten the "tired" white of the eyes.

Regarding the blue color of the drug, this is facilitated by the presence of methylene blue dye in Okumetil.

With regard to pharmacokinetics, the topical application of Okumetil leads to its systemic absorption, and there is no information on the degree of its penetration into the eye tissue.

Indications for the use of the drug

Blue whitening eye drops are used for therapy with the following diagnoses and conditions:

discomfort in the eyes; to relieve eye irritation in the form of foreign body sensation, itching, redness and lacrimation; blepharoconjunctivitis; angular conjunctivitis (inflammation of the eye corners); acute atopic conjunctivitis; chronic conjunctivitis; combination of blepharoconjunctivitis with allergic conjunctivitis; combination of blepharoconjunctivitis and chronic nonspecific conjunctivitis.

Contraindications for use

Since the drug is subject to systemic absorption, its administration must be coordinated with a long list of contraindications, among which there is a place for the following aspects:

hypersensitivity to any of the components of the drug; epilepsy; cardiovascular disease particularly atherosclerosis, coronary artery disease and arterial hypertension; under 2 years of age; breastfeeding, pregnancy; diabetes; bronchial asthma; angle-closure glaucoma; the presence of hyperfunction in the thyroid gland; prostate hyperplasia; pheochromocytoma; stenosis of a stomach ulcer, duodenal ulcer or bladder neck; dry eye syndrome.

In addition to the listed diseases and conditions, Okumetil is used with caution if you drink MAO inhibitors or a number of other drugs that can raise blood pressure.

Adult dosage and possible side effects

At the end of the three-day period of treatment and the absence of any therapeutic effect, the use of the drug, as a rule, should be stopped after consulting a doctor.

In the absence of the lens, scotoma and maculopathy occur. In this case, the drug is canceled, and the negative effects disappear.

In connection with possible manifestations, patients are advised not to resort to driving vehicles or working on equipment that requires increased concentration of attention.

Negative effects in overdose were not found.

Useful video on the topic

Features of use in children

The scheme and dosage of taking the drug are similar to those recommended for adult patients.

In the next few minutes after topical application, some patients experience pupil dilation and some visual impairment. These signs will disappear over time.

Other reactions are also possible:

burning; manifestations of an allergic type; accommodation paresis; swelling of the ocular mucosa; reactive hyperemia; violation of motor coordination; increase in blood pressure; weakness; drowsiness; tachycardia; nausea; allergy to ultraviolet; headache; dizziness; numbness and dryness of mucous membranes; decrease in the reaction rate.

The first aid in such conditions is considered mandatory gastric lavage, oxygen inhalation, the use of anticonvulsants and / or phentolamine (to stop hypertension), the use of activated carbon. The use of the drug in accordance with medical recommendations excludes a possible overdose.

Drops of blue or blue color whitening Innoxa protein

Exclusively natural preparation Innoxa (blue drops) was made in France. Due to the specific staining of the solution, they are called blue (blue) or cornflower blue eye lotion.

Main purpose: moisturizing, reducing fatigue and eye irritation.

Release form: 10 ml glass bottle.

Pharm. action: the product removes dry eyes, redness, itching, reduces fatigue and helps to relax the eye. The tool is in harmony with the lacrimal fluid, which contributes to a wonderful rest of the eyes. Gives the whites of the eyes a bluish tint, which gives the look a special radiance.

Indications: symptomatic treatment of the consequences of various adverse factors, in particular, prolonged work at the computer, exposure to ultraviolet radiation, uncontrolled viewing of television programs, wearing contact lenses, wind and dust.


Method of application: two drops in the lower eyelid of the eye three times a day.

Contraindications: intolerance to the elements of the medication, age up to 14 years.

Side effects: not observed.

Overdose: not observed.

Interaction with other medications: not determined.

Okumetil eye drops are a combined drug that is widely used in ophthalmology. The drug has a pronounced anti-inflammatory, antiseptic, antiallergic, vasoconstrictive effect. Drops are prescribed for the treatment of eye diseases in adults and children, accompanied by an inflammatory process.

Drops Okumetil (Ocumethyl) are developed on the basis of three active ingredients- zinc sulfate, diphenhydramine hydrochloride, naphazoline hydrochloride. 10 ml of the drug solution contains 10 mg of each active ingredient.

As auxiliary ingredients are:

• sodium salt citric acid (sodium citrate);
• citric acid (tribasic carboxylic acid);
• benzalkonium chloride (ammonium compound);
• methylene blue (dye);
• sodium hydroxide (caustic soda);
• sodium chloride (sodium salt of hydrochloric acid);
• metolose (hypromellose 4000);
• distilled water.

Additional components are designed to enhance the effect of the drug.

Dosage form

The drug is produced in the form of drops for topical use. medicinal solution is a clear blue liquid (see photo). The product is packaged in sterile polyethylene bottles with a pipette dispenser for accurate dosing. The carton box contains one bottle with blue drops of 5 or 10 ml, also attached detailed instructions describing the characteristics of the drug. Manufacturer: HFC Alexandria, Egypt.

pharmachologic effect

The therapeutic effect of ophthalmic drops is based on the following properties of the active substances:

• zinc sulfate - has a drying, astringent, antiseptic, anti-inflammatory effect;
• diphenhydramine chloride - acts as a blocker of histamine receptors, eliminates irritation, swelling, reduces capillary permeability;
• naphazolin is an indirect adrenomimetic agent, has a local vasoconstrictor effect, fights edema, hyperemia.

Thus, Okumetil eye drops have a complex effect on the organ of vision.

The drug is characterized by systemic absorption after topical application. Partially enters the systemic circulation. Clinical Research in the field of pharmacokinetics has not been conducted. Therefore, there is no information on the degree of penetration of the drug into the tissues of the eyes.

Indications for use

The main indications for the appointment of Okumetil eye drops:

• angular conjunctivitis - bacterial inflammation of the conjunctiva, which is localized in the corners of the palpebral fissure;
• nonspecific conjunctivitis - an inflammatory reaction to external influences (dust, smoke);
• blepharoconjunctivitis - infectious inflammation of the eyelids and conjunctiva;
• conjunctivitis and blepharoconjunctivitis of an allergic nature.

In addition, a therapeutic solution is used to relieve unpleasant symptoms that occur when the organ of vision is irritated. For example, burning, itching, redness, discomfort, foreign body sensation.

What drops should be used for, the attending physician should say. Mostly the drug is used in complex therapy.

Contraindications for use

The medication has an impressive list of contraindications. Drops can not be used in the following conditions and diseases:

• angle-closure glaucoma (CUG);
• hypersensitivity to any component;
• stenosis of the neck of the bladder;
• gastric and duodenal ulcer with stenosis;
• hormone-dependent benign tumor- pheochromocytoma;
• diseases of the heart, blood vessels;
• bronchial asthma;
• epilepsy (falling);
• diabetes;
• endocrine disorders;
• severe atherosclerosis;
• prostate adenoma;
• dry eye syndrome;
• pregnancy and lactation;
• children's age up to two years.

The drug should be carefully administered to patients who use medications to increase blood pressure.

Method of application and dosage regimen

Apply eye drops only locally, instilled into the conjunctivitis sac. If there are no other recommendations of a specialist, then the drug is used according to the standard scheme (it is indicated in the instructions for use) - 1 drop in the affected eye up to 4 times a day. For the treatment of children, the frequency of use is reduced to 2 times a day.

Ophthalmic drops are instilled into the conjunctivitis sac. To do this, slightly pull the lower eyelid, tilt the head back. The instillation procedure is carried out without touching the mucosa with the tip of the pipette. This will prevent infection of the drug solution.

If after two days from the start of therapy there is no improvement in the condition, then this should be reported to the attending physician. Most likely, a new medication prescription will be required.

Side effects, overdose

Immediately after topical application, the following adverse reactions from the organ of vision may occur:

• burning;
• blurred vision;
• allergic reactions;
• increased intraocular pressure;
• puffiness;
• pupil dilation;
• paresis of accommodation (inability to see small details even up close).

Against the background of therapy in patients with the absence of the lens, a pathological lesion of the macula, the central part of the retina, is possible. Also often there is dryness, numbness of the mucous membrane of the eyes.

With prolonged use, there is a high probability of penetration of the drug into the systemic circulation, which threatens the following side effects:

• cardiopalmus;
• constant weakness, drowsiness;
• headache, muscle pain;
• dizziness;
• nausea;
• lack of coordination;
• increased blood pressure;
• decrease in psychomotor reactions.

There is no information on overdose. If side effects occur, you should contact an ophthalmologist who will adjust the dosage regimen or select another drug.

drug interaction

• stimulants of the central nervous system;
• medicines containing silver salt or lead;
• quinine-containing drugs;
• monoamine oxidase inhibitors (MAOs);
• medicines to lower blood pressure.

It can not be combined with local ophthalmic anesthetics, as well as with drugs Citral, Nafazolin, Ichthyol.

The combination with the listed groups of medicines can lead to undesirable consequences. More often, simultaneous administration threatens to increase or, conversely, reduce the therapeutic effect of Okumetil drops.

special instructions

After instillation, it is not recommended to immediately drive a car and engage in potentially dangerous work, because. Many patients often experience blurred vision after the procedure. You can perform work and drive a car after 20-30 minutes.

The bottle with the treatment solution is tightly closed after each instillation. Remove before procedure contact lenses, you can put on the ophthalmic device after 15 minutes.

Terms and conditions of storage

Shelf life is 3 years, after opening the dropper bottle - 1 month. Do not use after the expiry date stated on the original packaging. Store in a dark place, inaccessible to children and animals, where the temperature is not lower than 15°C and not higher than 25°C.

Terms of sale

From pharmacies, Okumetil drops are released without presenting a prescription form.

The cost of Okumetil drops depends on the pricing policy of the pharmacy and the region of Russia. The average price in the territory of the Russian Federation is 215 rubles per bottle of 10 ml.

Okumetil is a modern drug with a complex composition. The drug has many contraindications and side effects, so it is better to use it with the permission of a specialist. This is especially true for pediatric patients. Properly selected dosage regimen will avoid negative consequences.

Okumetil's analogs

Sometimes side effects appear during treatment. Therefore, the ophthalmologist often has to select a cheap or expensive substitute. Some of the best cheap analogues include: