Sinaflan analogues are non-hormonal. When will Sinaflan ointment help, and how can it be replaced? Ointment sinaflan analogues non-hormonal

The composition of 1 g of liniment or ointment includes 0.25 mg of the active substance.

As auxiliary ingredients in the liniment are present:

• propylene glycol;
• anhydrous;
• pentanol;
• stearic acid;
• nipagin;
• nipazole;
• purified water.

Auxiliary substances in the composition of the ointment:

• benzyl alcohol;
• propylene glycol;
• soft white paraffin;
• ceresin;
• lanolin.

Release form

Available in the following dosage forms:

• Ointment Sinaflan. It has a uniform consistency. Color from light yellow to deep yellow.
• Liniment light yellow.
• Cream Sinaflan.
• Gel Sinaflan.

Both liniment and ointment are placed in aluminum tubes of 10 g and 15 g. Each tube is placed in a separate cardboard box.

pharmachologic effect

Refers to glucocorticosteroids . Applied externally to eliminate inflammatory processes, .

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

You can often hear the question of whether Sinaflan is hormonal or not. This is a hormonal drug, but this is due to its high efficiency.

Fluocinolone acetonide binds to specific receptors in the cytoplasm of cells, which provokes an increase in mRNA synthesis. The result of exposure affects all metabolic processes in the cell.

Of the clinically significant effects, the following aspects of the effect on the cell can be named:

• inducing the synthesis of lipocort proteins, including lipomodulin, which leads to inhibition of the activity of phospholipase A2, which is one of the factors in the progression of the inflammatory response;
• stabilizes the cell membrane, which helps prevent;
• increases the rate of protein catabolism;
• reduces the migration of B- and T-lymphocytes and disrupts the interaction of these cells;
• inhibits the accumulation of leukocytes and macrophages at the site of inflammation;
• inhibits the action of hyaluronidase, reduces the level of formation of arachidonic acid, leukotrienes;
• affects the regulation of carbohydrate metabolism, reducing the consumption of glucose by tissues, which can lead to an increase in its concentration in;
• contributes to the retention of sodium and water ions, provokes the excretion of potassium and calcium, reduces the ability to absorb calcium;
• increases the synthesis of erythripoietins.

Such an effect on metabolic processes in the cell contributes to a noticeable effect in those cases for which the medicine is used - for acne and other inflammatory skin lesions.

Pharmacokinetics

Fluocinolone acetonide easily penetrates into all layers of the skin, but accumulates in the stratum corneum (may be detected even 15 days after completion of treatment). It enters the bloodstream in a small amount.

Biotransformation occurs in the liver. In this case, inactive ones are formed. Excretion occurs mainly due to the work of the kidneys.

Absorption of the drug occurs more intensively in the case of treatment of children, application to large areas of the skin, with regular use, application to the skin of the face or damaged skin.

Indications for use

Why use Sinaflan ointment and dosage forms drug? For the treatment of various inflammatory skin lesions of non-infectious etiology.

What does Sinaflan ointment help in most cases? You can list such indications for the use of ointment, gel, cream and liniment:

• different localization;
• body and scalp;
• red flat;
• itching skin of unknown etiology;
• discoid form;
• allergic rashes;
• multiform;
• small;
• inflammation at the site of an insect bite.

Contraindications

It is forbidden to use ointment or liniment in such cases;

• hypersensitivity to the active substance or auxiliary components of the drug;
• skin diseases caused by an infectious agent: bacteria, virus or fungus;
• skin lesions that are a manifestation;
• wound surface;
• diaper rash ;
• precancerous conditions of the skin,;
• presence on the area of ​​\u200b\u200bthe skin where the medicine needs to be applied;
• psoriasis , which progressed to the formation of plaques;
• (the use of Sinaflan for acne, which is actually acne, can cause an exacerbation of the disease);
• trophic ulcers on the lower limbs caused by varicose veins;
• any use for children under 2 years of age;
• use in ophthalmology and on the skin of the mammary glands is prohibited;
• and period.

Side effects

The question is hormonal ointment or not is often due to the fact that it is known that hormonal preparations actively affect the entire body. This also applies to Sinaflan. Side effects are not very common, but they can be quite varied.

On the part of the skin and subcutaneous adipose tissue, the appearance of:

• irritation of the skin;
• peeling of the skin or rashes in the form of papules or spots at the site of application of the medicine;
• hyperkeratosis ;
• furunculosis ;
• exacerbations pathological conditions skin that was present at the start of treatment;
• atrophic changes in the skin;
• burning sensation ;
• itching ;
• steroid acne ;
• folliculitis ;
• hair loss or excessive hair growth at the site of application of Sinaflan;
• pigmentation disorders .

From the side digestive system(it happens when applied to large areas of the skin):

• steroid.

From the endocrine organs:

• increased blood glucose levels;
• glycosuria ;
• in children - a slowdown in growth and development;
• when applied to large areas of the skin may develop adrenal insufficiency , Itsenko-Cushing's syndrome , steroid .

• hypersensitivity reactions;
• decline;
• exacerbation of chronic diseases;
• generalization of infectious lesions;
• slowing down the reparation process.

From the side of the heart and blood vessels:

• boost ;

When applied to the outer surface of the eyelids, there is a risk of developing and .

Application instruction of Sinaflan (Way and dosage)

Ointment Sinaflan, instructions for use

The ointment is applied to the affected area 1 or 2 times a day, lightly rubbed. The course of treatment for adults is up to 10 days, for children - no more than 5 days, for facial skin - no more than 1 day.

It is undesirable to use ointment under the bandage, with the exception of some forms psoriasis . But in this case, it is very important to change it regularly.

Liniment Sinaflan, instructions for use

Liniment can be applied 2-4 times a day. The course of treatment is the same in duration as when using the ointment.

Do not use under a closed dressing, but can be applied to a small area of ​​skin under an occlusive dressing.

Recommended for dry dermatoses .

How to apply Sinaflan cream or gel

Apply to the affected areas 1-4 times a day. The course lasts no more than 2 weeks.

The cream is more often used for wet dermatoses , and the gel - in case of damage to the skin of the scalp.

Overdose

An overdose can easily occur when the drug is applied to large areas of the skin, in case long-term treatment or applied to particularly sensitive areas, such as the face. There is also a high risk in the treatment of children with Sinaflan.

Possible overdose symptoms:

• edema ;
• promotion blood pressure ;
• burning , itching at the site of application of the drug;
• increased levels of glucose in the blood and urine;
• Itsenko-Cushing's syndrome .

Treatment for overdose is symptomatic. This shows the gradual abolition of Sinaflan.

Interaction

The drug interacts with many other drugs, so caution is necessary when using at the same time:

• with systemic glucocorticosteroids - the effectiveness of Sinaflan increases and the likelihood of developing side effects from its use;
• with non-hormonal anti-inflammatory drugs - the risk of developing both local and systemic adverse reactions of the body to each of the drugs increases;
• with antihypertensive, antiarrhythmic drugs, diuretics, potassium preparations - the effectiveness of these medicines decreases;
• with diuretics (except for potassium-sparing ones) - the likelihood of developing hypokalemia ;
• with vaccines - an inadequate immune response is possible due to the fact that the immune system is weakened and is not able to synthesize the necessary antibodies in a normal amount;
• with immunosuppressors - enhances the effect;
• with immunostimulants - suppresses the effect of these drugs on the immune system.

Terms of sale

On prescription.

Storage conditions

Store in a cool place, but do not freeze.

Best before date

The ointment is stored for 5 years, liniment for 2 years.

special instructions

When treating with Sinaflan, it is necessary to adhere to the following recommendations:

• avoid getting medication in the eyes;
• do not apply to wounds, skin of the mammary glands;
• it is strictly forbidden to exceed the recommended duration of the course of treatment;
• do not use with other topical medicines;
• it is undesirable to use it under a bandage, since in this case the adsorption of the drug and the risk of developing systemic side effects increase;
• if necessary, several times to undergo a course of treatment, you need to take tests to monitor the functioning of the adrenal glands.

children

It is forbidden to use under the age of 2 years.

After 2 years, Sinaflan for children is prescribed with caution, for a short period and only under the supervision of a physician.

When used in the treatment of children, it is forbidden to apply the medicine to the skin of the face.

During pregnancy and lactation

Prohibited use when pregnancy and in lactation period , since there is not enough research on the effect of the drug on the child's body.

Sinaflan's analogs

Sinoflan's analogs:

• ointment Sinoflan-Fitofarm (an analogue with an identical composition, manufactured by the manufacturer PJSC Fitopharm);
• Flutsar-Darnitsa ;
• Flutsederm ;
• (gel and ointment).

Ointment from light yellow to yellow.

Pharmacotherapeutic group

Highly active corticosteroids ( group III). ATX code: D07AC04.

pharmachologic effect

Glucocorticosteroid for external use. It has anti-inflammatory, antiallergic, antiexudative and antipruritic action. Reduces manifestations and eliminates the inflammatory skin reaction.

Pharmacokinetics

After absorption from the skin surface, it binds to plasma proteins and is metabolized in the liver to form inactive metabolites. It is excreted mainly by the kidneys.

Indications for use

For the short-term treatment of inflammatory and allergic diseases skin that reacts to local glucocorticosteroids and proceeds with persistent itching or hyperkeratosis.

Anhydrous, fat-containing ointment Sinaflan is preferred for dry skin and chronic processes.

Contraindications

Hypersensitivity to the components of the drug; bacterial, viral, fungal skin diseases- pyoderma, chicken pox, herpes, actinomycosis, blastomycosis, sporotrichosis; skin manifestations syphilis, skin tuberculosis, diaper rash, rosacea, extensive psoriatic rashes (plaques), anogenital itching; trophic ulcers of the lower leg associated with varicose veins veins, erosive and ulcerative lesions of the gastrointestinal tract, wounds in the areas of application; skin cancer, nevus, atheroma, melanoma, hemangioma, xanthoma, sarcoma; pregnancy and lactation, children's age (up to 2 years).

Dosage and administration

The drug is intended only for local application. Apply a small amount of the drug 1-2 times a day and lightly rub. Children over 2 years of age are used with caution 1 time per day under medical supervision. The duration of treatment depends on the nature of the disease and is usually 5-10 days, with a long course of the disease - no more than 2-3 weeks. Avoid applying medicinal product on large (more than 20% of the body surface) lesions. Perhaps the combined use of Sinaflan ointment with non-drug ointment, while Sinaflan ointment is applied once a day 12 hours after applying the non-drug ointment. Do not apply ointment under an occlusive dressing.

Children more sensitive than adults: with topical application of glucocorticosteroids, the drug may enter the body. Therefore, Sinaflan ointment is used briefly (no more than 5 days) and with the lowest effective dose in children. In children, the drug should be used only for small areas of the skin (up to 10% of the body surface area). It is not allowed to apply ointment on the face of a child.

Side effect

The assessment of undesirable effects is based on the following data on the frequency of occurrence: very often (≥ 1/10), often (≥ 1/100 to From the skin and subcutaneous tissue :

Infrequently: urticaria, allergic contact dermatitis, skin irritation, striae (band-like atrophy of the skin), maculopapular rash, skin maceration at the application sites, perioral dermatitis, furunculosis. It is possible to develop secondary infectious skin lesions and atrophic changes in it (burning, itching, dry skin, steroid acne, folliculitis).

With prolonged use, skin atrophy, local hirsutism, telangiectasia, purpura, pigmentation disorders, hypertrichosis, alopecia are possible, especially in women.

From the digestive system:

Unknown: when applied to large areas of the skin, gastritis, steroid stomach ulcers are possible.

Endoc siderinny system:

Unknown: hyperglycemia. When applied to large areas of the skin, systemic manifestations are possible: adrenal insufficiency, Itsenko-Cushing's syndrome, steroid diabetes mellitus.

From the immune system:

Unknown: decrease in body resistance. With prolonged use, the following are possible: secondary immunodeficiency (exacerbation of chronic infectious diseases, generalization of the infectious process, development of opportunistic infections), slowing down of reparative processes.

From the sidetheycardiovascularsystems:

Unknown: arterial hypertension possible development of edema.

In case of occurrence adverse reactions, including those not listed in given instructions, you should stop using the drug and consult a doctor chu.

Overdose

Symptoms: itching, burning of the skin at the site of application of the drug, gynerglycemia, glucosuria, Itsenko-Cushing's syndrome.

Treatment: symptomatic against the background of the gradual withdrawal of the drug.

Precautionary measures

Use the drug with caution in girls during puberty. Apply only in short courses on small areas of the skin. It is recommended to wear loose clothing during treatment.

In patients with acne vulgaris or rosacea during treatment, an exacerbation of the disease is possible.

To prevent local infectious complications, it is recommended to prescribe in combination with antimicrobial agents.

If the drug causes symptoms of irritation or skin allergic reactions(skin itching, burning or redness), its use should be stopped immediately. With prolonged use on a large surface of the body, the frequency of manifestation of side effects and the possibility of developing edema, hypertension, hyperglycemia, and a decrease in body resistance increase.

When using occlusive dressings, due to increased bioavailability, it is possible to develop general resorptive effects characteristic of GCS. With external use of the drug, the following are possible: a decrease in the production of ACTH by the pituitary gland, inhibition of the adrenal glands-pituitary gland, a decrease in the level of cortisol in the blood and the development of Itsenko-Cushing's iatrogenic syndrome, which disappears after discontinuation of the drug. Periodic monitoring of adrenal function is shown by determining cortisol in the blood and urine after stimulation of the adrenal glands with ACTH with prolonged use. If an infection develops at the site of application of the drug, treatment should be discontinued and appropriate antibacterial or antifungal treatment should be carried out. The drug should be used with caution in the presence of subcutaneous tissue atrophy, mainly in elderly patients. Avoid getting the drug in the eyes, mucous membranes and wounds. Do not use on breast skin. Use with extreme caution in the treatment of patients with psoriasis, since topical use of glucocorticosteroids in psoriasis can be dangerous due to recurrence of the disease caused by the development of drug resistance, the risk of generalized pustular psoriasis and systemic toxicity caused by skin dysfunction. On the skin of the face, as well as on the skin of the groin and armpits, apply only in cases of special need, taking into account the increased absorption and the high risk of side effects (telangiectasia, oral dermatitis), even after short-term use. During treatment, it is not recommended to vaccinate against smallpox, as well as to carry out other types of immunization (especially with prolonged use on large areas of the skin) due to the possible lack of an adequate immunological response in the form of the production of appropriate antibodies. Contains lanolin. May cause local skin reactions (eg contact dermatitis). Contains propylene glycol. May cause skin irritation. When using the ointment in the genital or anal area, due to the Vaseline excipient, a decrease in strength and rupture of latex condoms may occur.

Use during pregnancy and lactation

The use of the drug during pregnancy and lactation is contraindicated.

Use in children

Because the surface area/body weight ratio is higher in children than in adults, they are at higher risk of systemic side effects of glucocorticosteroids, including hypothalamic-pituitary-adrenal axis dysfunction and Cushing's syndrome. Corticosteroid therapy may side effect on the growth and development of children. Periodic monitoring of the function of the adrenal cortex is shown by determining cortisol in the blood and in the urine after stimulation of the adrenal glands with ACTH. The use of the drug in children under the age of 2 years is contraindicated.

Influence atability to drive vehicles or other mechanisms

No data.

Best before date

5 years. Do not use the drug after the expiration date.

Terms of dispensing from pharmacies

On prescription.

Manufacturer/organization accepting claims

Instructions for use. Contraindications and release form.

Composition and form of release

Ointment for external use

100 g of ointment contain active substance fluocinolone acetonide 25 mg.

Tube 10 g; 15 y.

pharmachologic effect

Sinaflan is a glucocorticosteroid for topical use. It has anti-inflammatory, antiallergic, antiexudative and antipruritic action. Reduces manifestations and eliminates the inflammatory skin reaction.

Indications

Inflammatory and allergic skin diseases of non-microbial etiology:
- Seborrheic dermatitis.
- Eczema various genesis and localization.
- Neurodermatitis.
- Skin itching.
- Psoriasis.
- sunburn.
- Insect bites.
- Other chronic forms inflammatory and allergic skin diseases accompanied by dry skin.

Contraindications

Hypersensitivity to the components of the drug.
- Bacterial, viral, fungal skin diseases.
- Anogenital itching, pyoderma, skin tumors.
- Infectious diseases skin: skin manifestations of syphilis, skin tuberculosis, diaper rash, rosacea.
- Extensive psoriatic rashes (plaques).
- Trophic ulcers shins associated with varicose veins.
- Pregnancy and lactation period.
- Childhood(up to 1 year).
Use with caution in girls during puberty.

Dosage and administration

Outwardly. On the skin, previously wiped with a swab moistened with an antiseptic liquid, apply a small amount of the drug 2-4 times a day and lightly rub. The duration of treatment depends on the nature of the disease and is usually 5-10 days, with a long course of the disease - up to 25 days. With limited lesions, to enhance the effect, the ointment can be used under an occlusive dressing. It is not allowed to use more than 2 g of ointment per day under a bandage. It is preferable to use the ointment for dry forms of dermatoses.

special instructions

Apply only in short courses on small areas of the skin. The drug should not be applied to the face. Avoid getting the drug in the eyes. The duration of the appointment in children should not exceed 5 days. It is recommended to wear loose clothing during treatment. In patients with acne vulgaris or rosacea during treatment, an exacerbation of the disease is possible. To prevent local infectious complications, it is recommended to prescribe in combination with antimicrobial agents.

drug interaction

Compatible with antimicrobial agents. Reduces the activity of antihypertensive, diuretic, antiarrhythmic drugs, potassium preparations. Diuretic drugs (other than potassium-sparing ones) increase the risk of hypokalemia.

Overdose

Symptoms: itching, burning of the skin at the site of application of the ointment, hyperglycemia, glucosuria, Itsenko-Cushing's syndrome.
Treatment: symptomatic against the background of the gradual withdrawal of the drug.

Storage conditions

In a dry, cool place.

Keep out of the reach of children.

Best before date

Sinaflan ointment is a thick homogeneous gel-glucocorticosteroid of a light yellow hue for external use. It is produced in the form of an ointment at a concentration of 0.025% in an aluminum tube with a volume of 10 or 15 g. The tube is also additionally packaged in a small cardboard box with an enclosed instruction. What is Siaflan ointment for: instructions for use and how much does Sinaflan cost?

The product is not intended for internal use, strictly for external use! What is Sinaflan-phytopharm ointment used for:

• inflammatory processes on the skin of a chronic form;
• various dermatitis;
• Sinaflan relieves the symptoms of psoriasis;
• severe burns;
• insect bites;
• severe itching of the skin;
• non-infectious diseases of the skin.

Ointment Sinaflan in the photo:

Fluocinolone acetonide is the main active ingredient (1 g of the agent is equivalent to 250 mcg of fluocinolone acetonide). There are additional components such as medical vaseline, lanolin, propylene glycol and ceresin.

As part of the Sinaflan ointment, there is a hormone that is produced by the adrenal glands - a glucocorticoid. It is the hormonal composition of the drug that provides a quick result. However, their use may not go unnoticed:

• change in hair growth in the area of ​​​​treatment with ointment (both upward and downward);
• the formation of spider veins;
• skin pigmentation, etc.

That's why this remedy should be used strictly according to the doctor's prescription, despite its free sale in pharmacy retail.

Ointment for external use Sinaflan is indicated for use from the age of three.

The rules for using the remedy are determined only by the attending physician personally for his patient, based on the disease and age of the patient.

Sinaflan gel must be applied in a thin layer on a clean, dry skin covering with a frequency of 2-4 times a day. The average duration of treatment with Sinaflan is 5-7 days. If you do not achieve the expected result, you should contact your doctor.

For more severe dermatological diseases, it is allowed to use dressings with their further change at intervals of 2 times a day.

When using the product for a long time on large skin areas, the following overdose symptoms appear:

• disruption of the organs of the endocrine system;
• active growth of unwanted hair growth at the site of application of the ointment;
• adrenal insufficiency.

If you notice the above symptoms, you should immediately stop using the product and contact your doctor. As a rule, after stopping the use of the remedy, all negative signs disappear on their own.

Sinaflan liniment must not be used simultaneously with other glucocorticosteroids, since this increases the appearance side effects and overdose.

In severe dermatological diseases, Sinaflan can be combined with the use of antimicrobial and anti-inflammatory drugs inside.

Is it possible to smear Sinaflan on the face with rashes on it? Not recommended. But with some exceptions it is possible. Wash your hands before using the product to prevent infection. After using the product, you should also wash your hands well with soap and water to avoid getting any residue of the drug in your eyes. If the ointment gets into the eyes, immediately rinse them with water and consult an ophthalmologist as soon as possible.

For children from 2 to 5 years old, before using Sinaflan ointment, you must first mix it with the Children's cream in a ratio of 50:50 to reduce the likelihood of side effects and overdoses.

The end of the use of the product should not be abrupt. The volume of the ointment during application should be reduced every day or mixed with the "Children's" cream, while increasing the proportion of the cream daily, and decreasing the ointment accordingly.

Sinaflan ointment should not be used by pregnant women, because the main substance can enter the uterus through the placenta. There are no studies on the effect of the drug on the potential child of a pregnant woman. Therefore, it is better not to risk your own and the health of future children.
During lactation, it is also forbidden to use Sinaflan, because its components are able to be absorbed into the blood and in a small, but still, amount stand out in the composition breast milk. With an urgent need for its use, breastfeeding is stopped, and the child is transferred to artificial feeding.

• itching and burning at the site of application;
• appearance acne at the site of application;
• alopecia;
• active growth of hairy vegetation at the application site;
• the appearance of various pigmentation of the skin;
• hypertrichosis.

When using the product for a long time and on large areas of the skin, the following side effects may occur:

• gastritis;
• the appearance of ulcers in the organs of the digestive tract;
• Itsenko-Cushing's syndrome;
• adrenal insufficiency;
• diabetes.

The cost of the product ranges from 40 to 80 rubles, depending on the manufacturer and the mass of the tube. The average cost is 60 rubles (prices are given for Moscow).

This medical device there are analogues:

• Flucinar ointment;
• Sinoderm cream;
• Flunolone ointment.

All of the above analogues of Sinaflan belong to the group of glucocorticosteroids, therefore they are hormonal. Each remedy has its own contraindications, so self-replacement of the extreme is not recommended, only with the permission of the attending physician.

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What to do if a child has lice:

Before using medicinal ointment it is mandatory to read the instructions in order to exclude cases of contraindications:

• age up to two years;
• individual intolerance to the components of the product or allergy;
• purulent processes on the skin;
• streptoderma;
• diaper dermatitis;
• skin tuberculosis.
• pregnancy and lactation.

Adolescents should be especially careful when using a remedy for relieving skin problems during puberty.

The tool is sold practically in any pharmacy retail, it is sold without a prescription from the attending doctor. Sinaflan should be stored in a cool dark place (a refrigerator is best suited for this purpose). Screw the cap back on tightly after use.

The shelf life of the product is 5 years, pay attention to the date of manufacture and packaging, since medicines are not returnable.

At the end of the expiration date of the medicinal product, stop using it, and it is better to get rid of the expired product immediately.

About skin diseases and their treatment on video:

This page contains a list of all Sinaflan analogues by composition and indications for use. A list of cheap analogues, and you can also compare prices in pharmacies.

• Most cheap analogue Sinaflan:
• The most popular analogue of Sinaflan:
• ATH classification: fluocinolone acetonide
• Active ingredients / composition: fluocinolone acetonide

Cheap analogues Sinaflan

When calculating the cost cheap analogues Sinaflan the minimum price was taken into account, which was found in the price lists provided by pharmacies

Popular analogues Sinaflan

The list of drug analogues based on the statistics of the most requested medicines

All analogues Sinaflan

Analogues in composition and indications for use

The above list of analogues of drugs, which indicates Synaflan substitutes, is the most suitable, since they have the same composition of active ingredients and match the indications for use

Analogues by indication and method of application

Different composition, may coincide in indication and method of application

To compile a list of cheap analogues of expensive drugs, we use the prices provided by more than 10,000 pharmacies throughout Russia. The database of drugs and their analogues is updated daily, so the information provided on our website is always up-to-date as of the current day. If you have not found the analogue you are interested in, please use the search above and select the medicine you are interested in from the list. On the page of each of them you will find all possible options for analogues of the desired medicine, as well as prices and addresses of pharmacies in which it is available.

How to find a cheap analogue of an expensive medicine?

Sinaflan price

Sinaflan instruction

Composition and form of release

Ointment for external use

100 g of ointment contains the active substance fluocinolone acetonide 25 mg.

Tube 10 g; 15 y.

pharmachologic effect

Sinaflan is a glucocorticosteroid for topical use. It has anti-inflammatory, antiallergic, antiexudative and antipruritic action. Reduces manifestations and eliminates the inflammatory skin reaction.

Indications

Inflammatory and allergic skin diseases of non-microbial etiology:
- Seborrheic dermatitis.
- Eczema of various genesis and localization.
- Neurodermatitis.
- Skin itching.
- Psoriasis.
- Sunburn.
- Insect bites.
- Other chronic forms of inflammatory and allergic skin diseases accompanied by dry skin.

Contraindications

Hypersensitivity to the components of the drug.
- Bacterial, viral, fungal skin diseases.
- Anogenital itching, pyoderma, skin tumors.
- Infectious skin diseases: skin manifestations of syphilis, skin tuberculosis, diaper rash, rosacea.
- Extensive psoriatic rashes (plaques).
- Trophic leg ulcers associated with varicose veins.
- Pregnancy and lactation period.
- Children's age (up to 1 year).
Use with caution in girls during puberty.

Dosage and administration

Outwardly. On the skin, previously wiped with a swab moistened with an antiseptic liquid, apply a small amount of the drug 2-4 times a day and lightly rub. The duration of treatment depends on the nature of the disease and is usually 5-10 days, with a long course of the disease - up to 25 days. With limited lesions, to enhance the effect, the ointment can be used under an occlusive dressing. It is not allowed to use more than 2 g of ointment per day under a bandage. It is preferable to use the ointment for dry forms of dermatoses.

special instructions

Apply only in short courses on small areas of the skin. The drug should not be applied to the face. Avoid getting the drug in the eyes. The duration of the appointment in children should not exceed 5 days. It is recommended to wear loose clothing during treatment. In patients with acne vulgaris or rosacea during treatment, an exacerbation of the disease is possible. To prevent local infectious complications, it is recommended to prescribe in combination with antimicrobial agents.

drug interaction

Compatible with antimicrobial agents. Reduces the activity of antihypertensive, diuretic, antiarrhythmic drugs, potassium preparations. Diuretic drugs (other than potassium-sparing ones) increase the risk of hypokalemia.

Overdose

Symptoms: itching, burning of the skin at the site of application of the ointment, hyperglycemia, glucosuria, Itsenko-Cushing's syndrome.
Treatment: symptomatic against the background of the gradual withdrawal of the drug.

Storage conditions

In a dry, cool place.

Keep out of the reach of children.

Best before date