Analogues are cheaper than amoxiclav. Amoxiclav: instructions for use and high-quality, but cheap analogues Amoxiclav suspension analogues are cheaper

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The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

Compound

The composition of the drug Amoxiclav includes the antibiotic amoxicillin trihydrate and the potassium salt of clavulanic acid, which is an enzyme inhibitor. Belongs to the pharmacological group of penicillins.

Release form

Available in the form:
  • film-coated tablets;
  • powder for suspensions;
  • lyophilized powder for injection.
One 375 mg tablet contains 250 mg of amoxicillin and 125 mg of clavulanic acid.

The 625 mg tablet contains 500 mg of amoxicillin, 125 mg of clavulonic acid.

Auxiliary substances are:

  • silicon dioxide (colloidal);
  • croscarmellose (sodium salt);
  • magnesium stearate;
  • talc;
  • hypromellose;
  • ethylcellulose;
  • polysorbate;
  • titanium dioxide;
  • triethyl citrate.
Tablets are packed into bottles, 15 pieces in everyone. One box contains one bottle of medicine.

Powder for suspension is available in dark glass bottles, one per box. There is also a measuring spoon. The composition of the usual ready-made suspension includes 125 and 31.25 mg active substances respectively. When preparing the suspension "Amoxiclav Forte", 5 ml contains twice as much active ingredients - 250 and 62.5 mg, respectively. Auxiliary substances are:

  • lemon acid;
  • sodium citrate;
  • sodium benzoate;
  • carmellose sodium;
  • silica colloid;
  • sodium saccharin;
  • mannitol;
  • strawberry and wild cherry flavors.
For injection, a lyophilized powder is produced in vials of 0.6 and 1.2 g. The content of amoxicillin sodium salt in the solution is 500 or 1000 mg, and potassium salt clavulanic acid - 100 and 200 mg, respectively. One box contains 5 vials.

pharmachologic effect

The combination of amoxicillin with clavulanic acid is unique in its kind. Amoxicillin and other antibiotics of the penicillin group cause the death of bacterial cells by binding to their surface receptors. However, most bacteria during the use of the drug have learned to destroy this antibiotic using the beta-lactamase enzyme. Clavulanic acid reduces the activity of this enzyme, so this drug has a very wide spectrum of action. It even kills strains of bacteria that are resistant to amoxicillin. The drug has a pronounced bacteriostatic and bactericidal effect on all types of streptococci (with the exception of methicillin-resistant strains), echinococci, listeria. Sensitive to amoxiclav and gram-negative bacteria:
  • bordetella;
  • brucella;
  • klebsiella;
  • moraxella;
  • Proteus;
  • shigella;
  • clostridium and others.
Regardless of the combination with food intake, the drug is well absorbed into the body, the maximum concentration of the drug is reached already in the first hour after ingestion. It has a high rate and volume of distribution in the body - in the lungs, pleural, synovial fluids, tonsils, prostate, muscle and adipose tissue, sinuses, middle ear. In tissues, the highest concentrations of amoxiclav are observed one hour after the maximum in blood plasma. It passes into breast milk in insignificant amounts. Amoxicillin undergoes partial destruction in the body, and clavulanic acid is metabolized very intensively. Excreted by the kidneys. Insignificant excretion is carried out by the lungs and intestines. The half-life in healthy kidneys is 1-1.5 hours. Slightly excreted from the blood during dialysis.

Indications

The use of this antibiotic is prescribed for the treatment of various infectious diseases:
  • Diseases respiratory tract- sinusitis (acute or chronic), inflammation of the middle ear, pharyngeal abscess, bronchitis, tonsillopharyngitis, pneumonia and others.
  • Diseases of the urinary tract - cystitis, pyelonephritis, urethritis and others.
  • Gynecological infections, endometritis, septic abortion, salpingitis, and others.
  • Inflammation of the biliary tract (cholangitis, cholecystitis).
  • Connective and bone tissue infections.
  • Infections of soft tissues and skin (bites, phlegmon, wound infection).
  • Odontogenic infections, in which the pathogen enters the body through cavities in the teeth.

Amoxiclav tablets and powder - instructions for use

Amoxiclav is prescribed in different ways. The method of administration depends on the age and weight of the patient, the severity of the infection, the condition of the kidneys and liver. Optimal time the use of the drug is the beginning of the meal. The course of taking this medication lasts from 5 to 14 days, it can not be used longer.

For children under 12- 40 mg per kilogram of body weight per day.
For children whose weight exceeds 40 kg, the drug is prescribed as adults.

Adults are prescribed: 375 mg tablets are taken every 8 hours around the clock, 625 mg tablets every 12 hours. When prescribing a drug for the treatment of severe infections, doses of 625 mg every 8 hours, or 1000 mg every 12 hours, are used.

It should be noted that tablets may differ in the proportions of active ingredients. Therefore, you cannot replace a 625 mg tablet (500 g amoxicillin and 125 g clavulanic acid) with two 375 mg tablets (250 g amoxicillin and 125 g clavulanic acid).

For the treatment of odontogenic infections, the following scheme is used. The 375 mg tablets are taken every 8 hours, around the clock. Tablets 625 mg every 12 hours.

If it is necessary to use a drug for the treatment of patients with kidney disease, the content of creatinine in the urine must be taken into account. In patients with liver disease, constant monitoring of its function is necessary.

Powder for the preparation of suspensions is used for newborns and children up to 3 months. Dosing is carried out using a special measuring pipette or spoon. Dosage - 30 mg of amoxicillin per kilogram of body weight, twice a day.

For children over three months old for mild and moderate infections - 20 mg / kg of body weight, and for severe infections - 40 mg / kg. The second dose is also used in the treatment of deep infections - inflammation of the middle ear, sinusitis, bronchitis, pneumonia. To this medicine instructions are attached, in which there are special tables that allow you to calculate the doses of the drug necessary for children as accurately as possible.

The maximum allowable daily dose of amoxicillin for children is 45 mg / kg of body weight, for adults - 6 grams. Clavulanic acid can be taken per day no more than 600 mg for adults and 10 mg/kg for children.

Description of release forms

Suspension

Powder for oral suspension is used for children. Five milliliters of the finished suspension contains amoxicillin trihydrate 250 mg and potassium salt of clavulanic acid - 62.5 mg. Or 5 ml may contain 125 mg of amoxicillin and 31.5 mg of clavulanic acid. To give the suspension a pleasant taste, it contains sweet substances and fruit flavors. The powder for the preparation of the suspension is packaged in dark glass bottles. The volume of bottles is 35, 50, 70 or 140 ml. A dosing spoon is included in the box with the bottle.

Tablets

This medicine is available in the form of film-coated tablets that are white or beige-white in color. Tablets have an oval biconvex shape.

One 625 mg tablet contains 500 mg of amoxicillin trihydrate with 125 mg of clavulanic acid (potassium salt).

Tablets can be produced in plastic jars (15 tablets each) or in aluminum blisters of 5 or 7 pieces.

Tablets of 1000 mg are also coated, have an oblong shape with beveled edges. They are stamped "AMS" on one side and "875/125" on the other. They contain 875 mg of the antibiotic and 125 mg of clavulanic acid.

Amoxiclav 125

This is the name of the powder for the preparation of a suspension containing 5 ml of 125 mg of amoxicillin and 31.5 mg of clavulanic acid. Produced in bottles of 100 ml, in a cardboard box with a dosing spoon. The dosage is indicated in the section "Amoxiclav - instructions for use".

Amoxiclav 250 ("Amoxiclav Forte")

This is also a suspension powder, but it contains a double dose of amoxicillin - 250 mg in 5 ml and 62.5 mg of clavulanic acid. This suspension is called "Amoxiclav Forte" because of the increased dose of the antibiotic in its composition. The dosage is indicated in the section "Amoxiclav - instructions for use".

Amoxiclav 500

These are Amoxiclav tablets - 625 mg, containing 500 mg of the antibiotic itself. Application and doses are indicated in the section "Amoxiclav instructions for use", and the composition and properties - in the section "Amoxiclav tablets".

Amoxiclav 875

These are Amoxiclav tablets - 1000 mg, containing 875 mg of the antibiotic itself, and 125 mg of clavulanic acid. Application and doses are indicated in the section on the method of application of the drug, and the composition and properties - in the section "Amoxiclav tablets".

Amoxiclav 625

The tablets contain 500 mg of amoxicillin and 125 mg of clavulanic acid. Application and doses are indicated in the section on the method of application of the drug, and the composition and properties - in the section "Amoxiclav tablets".

Amoxiclav 1000

The tablets contain 875 g of amoxicillin and 125 mg of clavulanic acid. Application and doses are indicated in the section on the method of application of the drug, and the composition and properties - in the section "Amoxiclav tablets".

Amoxiclav Quiktab

Fruit flavored fast-dissolving tablets containing either 500 mg amoxicillin and 125 mg clavulanic acid or 875 mg amoxicillin and 125 mg clavulanic acid.

Contraindications

When taking the drug, liver dysfunction and jaundice (cholestatic) may occur if this drug has already been used before and the patient has hypersensitivity to drug components, or to all penicillins.

Nervous system may respond to the drug with headaches, dizziness, agitation, insomnia, convulsions, inappropriate behavior or hyperactivity.

Liver. Increases in liver function tests, including asymptomatic increases in the activity of AST and / or ALT, alkaline phosphatase and serum bilirubin levels.

Leather. The skin can react to taking amoxiclav with a rash, urticaria, angioedema, rarely develops erythema multiforme, toxic epidermal necrolysis, exfoliative dermatitis, Stevens-Johnson syndrome.

urinary system - there is the appearance of blood in the urine and interstitial nephritis.
With prolonged use of the drug, fever, oral candidiasis, and candidal vaginitis may occur.

Amoxiclav during pregnancy

Amoxiclav should not be used during pregnancy. The exception is those cases where the benefit of taking the drug is higher than the harm it causes. Taking this medicine during pregnancy increases the risk of necrotizing colitis in newborns.

Amoxiclav for children

For children, powder for suspensions, regular and Amoxiclav Forte, is used. The method of application is described in the section Amoxiclav - method of application.

Amoxiclav with angina

Antibiotics for angina are prescribed only in cases of moderate and high severity. Amoxiclav, as an antibiotic of the penicillin series, is often prescribed for tonsillitis. Its use is indicated only when the bacterial form of the infection is confirmed, and the pathogenic microflora is tested for sensitivity to this drug. In the treatment of angina in children, suspensions are used, in adults - tablets. In severe cases, injections of the drug are used.

It must be remembered that antibiotics should not be used long time, as this increases the resistance of pathogenic microflora to them.

Compatibility with other medicines

  • It is undesirable to simultaneously use Amoxiclav and preparations of indirect anticoagulants. This may cause an increase in prothrombin time.
  • The interaction of Amoxiclav and allopurinol causes the risk of exanthema.
  • Amoxiclav enhances the toxicity of methotrexate.
  • You can not use amoxicillin and rifampicin at the same time - these are antagonist drugs, the combined use weakens the antibacterial effect of both.
  • You can not prescribe amoxiclav together with tetracyclines or macrolides (these are bacteriostatic antibiotics), as well as with sulfonamides due to a decrease in the effectiveness of this medication.
  • Taking Amoxiclav reduces the effectiveness of contraceptive pills.

Comparison with other drugs

What is better than Amoxiclav?

When choosing an antibiotic for the treatment of any infection, it is necessary to be guided by the results of testing pathogenic microflora for sensitivity to a particular antibiotic. It makes no sense to use a drug that does not kill bacteria - that is, it does not heal. Therefore, the antibiotic to which the pathogenic microflora of the patient is sensitive will be better.

Amoxiclav or amoxicillin?

Amoxiclav is more effective drug than amoxicillin because this antibiotic many pathogenic microorganisms have developed immunity and have learned to destroy it, preventing its bactericidal action from manifesting. The addition of clavulanic acid to amoxicillin made this antibiotic much more active, expanding its range of action.

Amoxiclav or Augmentin?

Augmentin is an analogue of Amoxiclav, contains the same active ingredients.

Amoxiclav or Flemoxin?

Flemoxin - medicine containing only amoxicillin. Without the use of clavulonic acid, it has a smaller spectrum of action, therefore, it is used only if the bacterial microflora is sensitive to this antibiotic.

Amoxiclav or Sumamed?

The composition of Sumamed includes the antibiotic azithromycin, which has a wide spectrum of action. The choice should be made on the basis of testing the sensitivity of pathogenic microflora to these two antibiotics. Side effects are similar.

Alcohol compatibility

During treatment with Amoxiclav, it is forbidden to take alcohol. The intake of alcoholic beverages significantly reduces the antibacterial effect of the drug.

Synonyms and analogues

Synonyms:
  • Augmentin;
  • Clavocin;
  • Moksiklav.
Analogues of Amoxiclav:
  • Amovicomb;
  • Arlet;
  • Bactoclav;
  • Klamosar;
  • Verclave;
  • Medoklav;
  • Liklav;
  • Panklav;
  • ranclave;
  • Rapiclav;
  • Toromentin;
  • Flemoklav;
  • Ecoclave;
  • Amoxicillin + clavulanic acid (Fizer) and others.

Reviews

Reviews of doctors

Anna Leonidovna, therapist, Vitebsk. Amoxiclav is much more effective in the treatment of various respiratory diseases than its counterpart, amoxicillin. I prescribe a course of 5 days, after which it is obligatory to take drugs that restore the microflora.

Veronika Pavlovna, urologist. city ​​of Krivoy Rog. This drug is excellent for bacterial infections of the genital tract. Rarely gives side effects, in parallel I prescribe antifungal drugs, after taking probiotics to restore normal microflora.

Andrey Evgenievich, ENT doctor, Polotsk. The use of this drug by injection allows you to quickly stop the manifestations of severe and moderate diseases of the ENT organs. The drug well treats inflammation of the middle ear. In addition, patients take the sweet fruit suspension well.

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    Anonymous user

    The user left his review anonymously

    My mother had cystitis and bakposev showed that the microbe is sensitive to amoxicillin clavulanate. And the urologist prescribed amoxiclav - the largest dosage 2 times a day. On the second day, terrible diarrhea began. Nothing could stop. The drug was canceled

    Sofia

    Amoxiclav is a very well-known antibiotic with a wide spectrum of action and has shown itself well in the treatment of many bacterial diseases. I warn you that antibiotics are prescribed only by a doctor, it is better not to self-medicate, as this can have a bad effect on our body. You can buy Amoxiclav even in an online pharmacy. The price of the drug depends on the dose. Amoxiclav is well tolerated in my family ... Amoxiclav is a very well-known antibiotic with a wide spectrum of action and has shown itself well in the treatment of many bacterial diseases.
    I warn you that antibiotics are prescribed only by a doctor, it is better not to self-medicate, as this can have a bad effect on our body.
    You can buy Amoxiclav even in an online pharmacy. The price of the drug depends on the dose.
    My family has well tolerated Amoxiclav, no one has ever had any reaction.
    But the effectiveness of taking Amoxiclav is very strong for any disease, and the result is observed already on the second day. The child, in the treatment of otitis, improved already on the second day, he began to complain less about pain in the ear and the temperature decreased on the same day.
    I treated inflammation in the tooth with Amoxiclav. The dentist prescribed me a dosage of 875 mg 2 times a day to relieve inflammation. After the start of the reception, a day later, I felt relief and the tooth stopped bothering me.
    Amoxiclav proved to be effective and strong antibacterial drug, but you need to take it only as directed by a doctor and very carefully. Not only is it very strong, but it can also cause various side effects.

    A strong drug but with a lot of side effects. His father was discharged from prostatitis, sowing showed sensitivity. He began to drink, and within three days diarrhea developed. As a result, I had to give up both drugs and smartprost for a week, the disease dragged on. I used to drink abactal and nolicin, they did not give such an effect.

    For the first time, he fell ill with such a severe infectious sore throat that on the 3rd day of self-treatment he could not eat from the pain and began to choke. I told my wife where all the capsules in the house are hidden (because I manage the home cash register) and went to surrender to the doctors. They wanted to take me straight to the hospital, but... For the first time, he fell ill with such a severe infectious sore throat that on the 3rd day of self-treatment he could not eat from the pain and began to choke. I told my wife where all the capsules in the house are hidden (because I manage the home cash register) and went to surrender to the doctors. They wanted to put me in the hospital right away, but I refused - Amoxiclav 2x was prescribed to me then. Literally after taking 2 tablets in the evening, I already felt relieved, and in the morning I sighed with renewed vigor and went on the mend.

    Although it is considered to be a simple antibiotic, it works great if it hits a point. At least, with his help, my husband cured prostatitis, and he didn’t take anything extra, he just went to smartprost. why drink something stronger if it helps and weak?

    Judging by the fact that amoxiclav is constantly prescribed to children, I thought that this antibiotic is rather weak and harmless. But it turns out that he is even able to defeat prostatitis, at least in combination with smartprost. I do not understand why then it is so often prescribed to children.

    Mikem

    Pharyngitis cured quickly, in a few days. But he caused inflammation of the intestines, which has not been cured for a month and a half. Although Bifiform ate while taking Amoxiclav, and now he just didn’t take anything. 7 weeks of hell, never had such complications with the stomach as after this antibiotic. Pharyngitis cured quickly, in a few days. But he caused inflammation of the intestines, which has not been cured for a month and a half.
    Although Bifiform ate while taking Amoxiclav, and now he just didn’t take anything. 7 weeks of hell, never had such complications with the stomach as after this antibiotic.

    Catherine

    Our daughter will be 4 years old and it’s already summer, and we got so sick that we didn’t even get so sick in winter. There was a terrible cough, a little later I heard that the child began to wheeze. They called the doctor to the house, after listening to the pediatrician said that there was a suspicion of pneumonia. Out of fear, we rushed to the hospital, took a picture, ... Our daughter will be 4 years old and it’s already summer, and we got so sick that we didn’t even get so sick in winter.
    There was a terrible cough, a little later I heard that the child began to wheeze. They called the doctor to the house, after listening to the pediatrician said that there was a suspicion of pneumonia. Out of fright, we rushed to the hospital, took a picture, it turned out that we had bronchitis, which needed to be treated urgently, because if we didn’t have much more, we would get pneumonia.
    Many drugs were prescribed, including the antibiotic Amoxiclav powder. He looks like this. This is Amoxiclav 2S - intended for use in children, can be given from 3 months.

    Inside is a bottle of powder.
    This is Amoxiclav for children in the form of a powder that must be diluted in water before being given to the child.
    The prepared solution is stored for no more than a week, in principle - this is a course of treatment.
    He helped us a lot. The child recovered quickly.

    For the first time I was advised this medicine by a very good dentist. Since then, I have been treating absolutely EVERYTHING with this antibiotic! Any infection is perfectly killed by this remedy. And often, as they say in that movie: one tablet is enough :) Of the side effects, for me personally, there is only a taste of this medicine in saliva, no more side effects ... For the first time I was advised this medicine by a very good dentist. Since then, I have been treating absolutely EVERYTHING with this antibiotic! Any infection is perfectly killed by this remedy. And often, as they say in that movie: one tablet is enough :)
    Of the side effects, for me personally, only the taste of this medicine in saliva, there have never been any other side effects.
    I take exclusively instant quicktab 875/125

    Got sick with ARI. Amoxiclav was prescribed. I felt the effect only on the 3rd day, but along with the decrease in temperature, wonderful side effects came: depression, terrible mood, yellow plaque on the teeth, which you can’t brush off with a brush, and then another month she was treated for dysbacteriosis (both in the intestines and in the vagina). I will no longer take this drug. Got sick with ARI. Amoxiclav was prescribed. I felt the effect only on the 3rd day, but along with a decrease in temperature, wonderful side effects came: depression, a terrible mood, yellow plaque on the teeth, which you can’t brush off, and then another month was treated for dysbacteriosis (both in the intestines and in the vagina).
    I will no longer take this drug.

    Yes, Amoxiclav is a strong antibiotic, but also effective. Regarding whether to give a child, well, the instructions say that it is possible from the first days of life. It is clear that an antibiotic is an antibiotic, but it happens that there is no other way out. I didn’t give it to a child, but I drank it myself with acute bronchitis. Puts... Yes, Amoxiclav is a strong antibiotic, but also effective. Regarding whether to give a child, well, the instructions say that it is possible from the first days of life. It is clear that an antibiotic is an antibiotic, but it happens that there is no other way out. I didn’t give it to a child, but I drank it myself with acute bronchitis. Puts on feet literally in 4-5 days. True, then you cough for another month, but first aid is excellent. And in order to avoid dysbacteriosis, you need to drink probiotics and know which ones, and not any of the list.

    We also caught a sore throat. The pediatrician prescribed Amoxiclav suspension. But she warned that Amoxiclav should be taken with an anti-allergic drug. I had the imprudence to disobey, you know how I thought, they say the child will take an antibiotic, and even shove him with other medicines: (In short, the next day we had a terrible disorder, a rash all over ... We also caught a sore throat. The pediatrician prescribed Amoxiclav suspension. But she warned that Amoxiclav should be taken with an anti-allergic drug. I had the imprudence to disobey, you know how I thought, they say the child will take an antibiotic, and even shove him with other medicines: (In short, the next day we had a terrible disorder, a rash all over our body and on our face. I called the pediatrician, she put me in “I really don’t want” that I’m mocking the child, that it was necessary to give an antihistamine with Amoxiclav and plus some kind of Linex or Bifidum ... So, of course, we cured a sore throat instantly, but we still earned ourselves sores. We consulted with a paid pediatrician and decided to replace Amoxiclav with Summamed. Although he also caused a terrible allergy in the child. And I concluded for myself - any antibiotic is harmful to the child, but here you really need to choose according to priorities, or treat a sore throat and save the child from high temperature or prevent allergies. We chose the first one.

Are there pregnancy restrictions?

Prohibited at breastfeeding

Has restrictions for children

Can be taken by the elderly

Has limitations for liver problems

Has limitations for kidney problems

Amoxiclav is a complex action agent that has antibacterial activity. It is active against various bacteria - mainly gram-positive. The drug is used to treat bacterial infections of various etiologies, which are caused by penicillin-sensitive bacteria.

Amoxiclav belongs to the group of combined penicillins and is not a budget drug. There are analogues that are cheaper, but contain the same active substances or belong to a different group of antibiotics, but have a similar effect.

The effect of the drug in angina

The composition of the drug includes two main substances: amoxicillin and clavulanic acid. The first is the active substance, which belongs to penicillins. It is due to the presence of amoxicillin in the composition that Amoxiclav is able to destroy bacteria.

Clavulanic acid is an excipient that can destroy an enzyme that some types of bacteria synthesize. This enzyme is called beta-lactamase, thanks to its synthesis, the bacterium can inactivate the antibiotic.

Amoxiclav is convenient in that there are several forms of release - both for oral and parenteral use. For internal use produce tablets and powder. For parenteral - powder vials intended for dilution with saline.

Amoxiclav has several structural analogues. They differ only in the manufacturer, their composition is identical. Below is a list of drugs, the price of which is lower, and the effect that the antibiotic has is identical:

  1. Augmentin. Available in several forms - for oral administration and parenteral administration. For oral administration, tablets and suspension are produced. For parenteral - powder for injection.
  2. Klavam. Available in powder form for suspension. There are no parenteral forms.
  3. clavuxicin. This is a powder that must be diluted for intravenous injections.
  4. Medoklav. Available in the form of tablets and powder for injection.

Below is a list of drugs, the price of which is lower, and the effect of the antibiotic is almost identical. The most budgetary funds are not full structural analogues of Amoxiclav or are based on another active substance.

This is the cheapest analogue of Amoxiclav. It contains only one medicinal substance - amoxicillin. This is the main difference from Amoxiclav.

The antibacterial effect that the drug has is almost the same. Amoxicillin is active against gram-positive and some gram-negative bacteria. Due to the action, the drug is indicated in the presence of the following infectious diseases:

  • bacterial damage to the ENT organs - tonsillitis, acute and chronic form, otitis;
  • inflammation of the lower respiratory tract of a bacterial nature - bronchiolitis, pneumonia;
  • purulent skin lesions.

Bactericidal action of amoxicillin

Amoxicillin is not recommended in cases where other antibiotics have been used for treatment in the last 2 months. In this case, the bacteria may become resistant, and the use of the drug will be ineffective. Other contraindications include impaired liver and kidney function, the development of allergies to any drug from the beta-lactam group.

A single dosage for treatment is 500 mg. You need to repeat the reception 3 times a day with an equal interval - every 8 hours. To use, you need to drink a tablet or capsule with a small amount of liquid. For young children, you can use a suspension, the dosage is calculated depending on the body weight of the child - 20 mg per kilogram of weight.

Taking Amoxicillin can cause side effects. The most common of these are allergic reactions. Taking the medication can cause a rash on the skin, itching, discomfort, redness. Less commonly, an allergy becomes generalized - systemic edema, signs of shock occur.

Less commonly, other adverse reactions develop:

  • dyspeptic phenomena;
  • headache;
  • disturbance of consciousness;
  • change in pulse and pressure.

The drug is an antibacterial agent that belongs to penicillins. The main difference lies in the composition (there is no clavulanic acid) and the form of release.

The main medicinal substance that is part of the drug is amoxicillin. Auxiliary components do not have a therapeutic effect, but only create the desired shape and consistency.

Medication indicated for the treatment of diseases of a bacterial nature, if the infection has the following localization:

  • skin and fiber;
  • respiratory system;
  • digestive tract.

The use of Flemoxin Solutab is not effective if the disease is caused by a bacterium that is able to synthesize specific enzymes against beta-lactams. In these cases, you need to choose another antibacterial agent.

The method of application of the drug is oral. Tablets are washed down with a small amount of liquid or dissolved in warm water. Eating does not affect the absorption of the substance.

On average, it is enough to use 500 mg of the drug three times a day. The interval between taking the tablets should be the same, thanks to this, a stable and constant concentration of the drug substance in the blood is created.

For children, the dose is selected individually. 20-40 mg per kilogram of weight is prescribed, depending on the specific infectious disease. It is not recommended to use an antibiotic as a prophylaxis, that is, in the absence of signs of infection. Also, with the help of the drug can not be treated viral diseases(including SARS).

Contraindications include severe pathology of the liver, urinary system, acute somatic diseases gastrointestinal tract. When taking the drug, there may be a feeling of nausea, vomiting, diarrhea, increased education. Allergies may also develop.

Azithromycin

Azithromycin is not a structural analogue of Amoxiclav, but has a similar effect. The spectrum of its action is quite wide, it applies to the same bacteria.

The main difference is that Azithromycin is not a penicillin, but belongs to the group of macrolides.

This is of practical importance in cases where the patient is allergic to any drug from the beta-lactam group. In this case, structural analogues (drugs from the same group) are contraindicated, and Azithromycin is approved for use.

Azithromycin acts on gram-positive and gram-negative flora, it is most effective in bacterial lesions of the upper respiratory tract:

  • acute inflammation of the tonsils;
  • inflammation of the middle ear;
  • inflammation of the pharynx, larynx.

Available in tablet and capsule form oral administration. For children, Azithromycin is available in the form of a suspension.

The advantage of Azithromycin is a short course of administration. For treatment, it is enough to use 1 tablet per day, 3 days in a row. This does not mean that Azithromycin is a weaker antibiotic than others. On the contrary, the concentration of the drug in the blood is higher, so the drug can be used less often (1 time in 24 hours).

Lower dosages are also used. When prescribing Amoxiclav 1000 mg, the analogue is Azithromycin with the lowest dosage of 250 mg.

Side effects when taking Azithromycin are rare, usually the drug is well tolerated. Severe allergic reactions are not characteristic, unlike penicillins. Dyspepsia may develop - nausea, diarrhea, flatulence. Less common are changes in the heart and blood vessels - tachycardia, decreased pressure, arrhythmias, dizziness.

It is contraindicated to use drugs from the group of macrolides in decompensated diseases of the kidneys and liver, cardiac arrhythmia.

The composition of Amosin includes one active substance - amoxicillin. This is an antibacterial agent from the group of unprotected penicillins. Amosin is not active against microorganisms that are capable of synthesizing beta-lactamase.

Indication for the use of Amosin is the presence of infectious diseases that are caused by bacteria sensitive to amoxicillin. With the help of Amosin, the following diseases can be treated:

  1. Pathologies of the respiratory tract, which are of a bacterial nature. For example, tonsillitis, pharyngitis, bronchitis, pneumonia.
  2. Bacterial lesions of the gastrointestinal tract - enteritis, colitis.
  3. Pathologies of the urinary system - pyelonephritis, cystitis.
  4. Purulent lesions of the skin.

The therapeutic effect of Amosin

Amosin exists only in the form of oral forms. The drug is available in the form of tablets and capsules. Produced for children special form- a suspension that is designed for convenient separation of the dosage and has a pleasant taste.

The daily dosage is selected individually depending on the severity of the disease and general condition sick. At lung diseases and moderate severity enough 1 tablet (500 mg) 3 times a day. In severe infections, a single dosage is increased to 750-1000 mg, the reception is repeated three times a day, after equal intervals of time.

It is contraindicated to use the drug for less than 5 days, as this is fraught with the formation of resistance.

The average duration of therapy is 5-10 days. When taking a medication, undesirable effects may develop - skin rash, itching, nausea, headache. Less commonly, severe manifestations of allergies develop - general edema, suffocation, signs of shock. It is contraindicated to use the drug for allergies to penicillins, diseases of the liver and kidneys.

Ampiox is a combination drug that belongs to the group of penicillins. The composition of the drug includes two active ingredients at once - ampicillin and oxacillin. Thanks to combined composition Ampiox has a stronger effect. Therefore, indications for its appointment are severe infections that may be insensitive to monotherapy.

The main difference from Amoxiclav lies in the composition - the absence of clavulanic acid, a representative of substances from the penicillin group.

Ampiox is prescribed in the presence of the following diseases:

  • bacterial inflammation of the lower respiratory tract - bronchitis, bronchiolitis, pneumonia;
  • infectious diseases of the urinary system - pyelonephritis, pyelitis, cystitis;
  • inflammation of the gallbladder;
  • pustular lesions of the skin.
  • septic conditions.

General information about the drug

Ampiox is not a first-line drug, therefore it is more often used after determining the sensitivity of bacteria to this antibiotic.

Ampiox is available in the form of tablets that are taken orally. A single dosage is often 500 mg (in severe infections it increases to 1000 mg). Reception of tablets is repeated 4 times a day - every 6 hours.

The drug may cause the development adverse reactions. The most common manifestations of allergies are skin rashes, swelling and redness. In rare cases, Quincke's edema develops and anaphylactic shock. Dyspeptic symptoms also develop - nausea, diarrhea, vomiting.

Before using the drug, you need to consult a doctor and make sure that there are no contraindications. Reception of Ampiox is contraindicated in the presence of such diseases:

  • allergies in history;
  • damage to the liver and kidneys.

Oksamp

Oksamp - combination drug, which has a pronounced antibacterial effect. It is a member of the penicillin group. The composition includes 2 active components - ampicillin, oxacillin. Oxamp is active against many bacteria that do not produce beta-lactamase.

Indications for prescribing a medication are the presence of severe infectious diseases that are caused by bacteria. With the help of Oxamp, the following diseases can be treated:

  • organ inflammation respiratory system- bacterial bronchitis, pneumonia, pleurisy;
  • defeat digestive system- cholecystitis, bacterial colitis;
  • blood poisoning;
  • purulent skin lesions, including erysipelas;
  • infectious diseases of the urinary organs - cystitis, pyelitis, cervicitis.

The drug is taken orally with a small amount of water. The daily dosage is selected individually. On average, 1 tablet (250 mg) is prescribed 4 times a day. If necessary, the dosage can be adjusted and increased. Tablets should be taken 1 hour before or after meals, as food intake does not affect the absorption of the drug. The course of therapy ranges from 7 to 14 days, the duration is selected individually.

When taking the medication, complications may develop. The most common are allergic reactions. Manifested in the form of rashes on the skin, itching, swelling of the skin and subcutaneous tissue. In severe cases, edema also captures the respiratory organs, while shortness of breath or suffocation develops. With the development of generalized complications, you need to stop taking the drug and seek medical help.

Nausea, vomiting, abdominal pain are less common. With prolonged use of Oxampa, dysbacteriosis may develop. Before using the medication, you need to familiarize yourself with the list of contraindications. It is forbidden to take Oksamp with a history of allergies, liver pathology, intolerance to any of the components.

Amoxiclav belongs to the category of broad-spectrum antibacterial agents. Thanks to this, the drug allows you to treat most bacterial infections. The medicine has contraindications and side effects, therefore it is prescribed exclusively by a doctor. In some cases, it is required to choose analogues cheaper than amoxiclav.

Characteristics of the drug

The composition of the drug includes an antibacterial component - amoxicillin trihydrate. It also contains clavulanic acid, which is an enzyme inhibitor. The drug belongs to the group of penicillins. It is produced in several forms - tablets, powders for injection and for the manufacture of suspensions.

The substance has an extensive spectrum of action and belongs to penicillins. The presence of clavulanic acid in the composition guarantees the resistance of the antibacterial component to the activity of β-lactamase produced by microorganisms.

The structure of clavulanic acid is similar to the structure of beta-lactam antibiotics, and therefore it also has an antibacterial effect. The composition of the drug makes it effective against major strains of bacteria.

Amoxiclav is prescribed for infectious and inflammatory pathologies. These include:

  • infections of the otolaryngological organs and upper respiratory tract - otitis media, sinusitis, tonsillitis, pharyngitis, etc.;
  • lesions of the urinary system - prostatitis, cystitis;
  • diseases of the lower respiratory tract - bronchitis and pneumonia;
  • infectious gynecological pathologies;
  • biliary tract damage - cholecystitis, cholangitis;
  • lesions of the epithelium and soft tissues;
  • infectious lesions of bone structures and connective tissues;
  • odontogenic diseases.

In general, adults and children weighing over 40 kg should drink 1 tablet at a dosage of 375 mg every 8 hours. Such treatment helps to cope with mild infections or pathologies of moderate severity. It is also quite possible to take 1 tablet every 12 hours at a dosage of 500 mg and 125 mg additionally.

  • In more complex cases and infectious lesions of the respiratory system, you need to drink 1 tablet every 8 hours with a dosage of 500 mg and 125 mg additionally.
  • In addition, the following dosage can be used: 1 tablet of 875 mg and 125 mg every 12 hours.

Depending on the pathology, the antibiotic is taken for 5-14 days. The doctor selects treatment depending on individual characteristics.

List of cheap analogues of Amoxiclav

This drug costs from 220 rubles. Analogues of amoxiclav are very diverse. They have a similar mechanism of action and the same active ingredients. So, according to the principle of impact on the body, it is worth highlighting the following analogues:

  • ampioks - costs about 70 rubles;
  • oxamp - will cost about 215 rubles;
  • klamosar - will cost 350 rubles.

Depending on the active ingredients, you can choose the following substances:

  • medoclave - costs about 280 rubles;
  • augmentin - costs about 260 rubles;
  • arlet - costs about 200 rubles;
  • ecoclave - will cost 200 rubles;
  • flemoklav solutab - will cost about 300 rubles;
  • amoxicillin - the cost is from 37 to 100 rubles.

Reviews of amoxiclav analogues confirm their high efficiency. However, these funds are not always cheaper. Therefore, when choosing a drug with a similar mechanism of action, it is necessary to take into account the dosage and the number of tablets in the package. Medical advice is also important.

Amoxiclav or amoxicillin

Amoxiclav or amoxicillin - which is better? This question is asked by many people. Both drugs are classified as penicillins and contain amoxicillin. At the same time, clavulanic acid is additionally present in the composition of amoxiclav. Due to this, the spectrum of action is significantly expanded.

As a result, when choosing amoxicillin or amoxiclav, it should be borne in mind that the second agent helps to cope with more severe infections. Amoxicillin does not eliminate beta-lactamase, which is its main disadvantage.

It can be concluded that amoxiclav is considered more effective means. At staph infection its action is much superior to amoxicillin. The key advantage of this tool is only its cost. Amoxicillin is much cheaper than amoxiclav.

Amoxiclav or Augmentin - what to choose

Augmentin or Amoxiclav - which is better? This question very relevant. These substances are structural analogues. They have the same composition, and therefore the indications, contraindications and other features are the same.

When choosing augmentin or amoxiclav, it is worth considering that the only fundamental difference is the manufacturer. Also, the funds have a slight difference in price. Tableted forms of drugs cost about the same, while powder for making a suspension is cheaper for Augmentin.

Amoxiclav or sumamed

Sumamed or amoxiclav - which is better? Answering this question, you need to understand that the drugs are completely different and belong to different pharmacological groups. This is due to the fact that the substances have different active ingredients.

When choosing sumamed or amoxiclav, it is worth considering age restrictions. So, amoxiclav can be used from birth, while sumamed is given starting from 6 months.

As for the cost, amoxiclav will be cheaper. However, sumamed implies a shorter course of therapy. Usually this substance is prescribed for 3 days, while penicillin antibiotics it is recommended to drink within a week. The speed of action of sumamed allows to reduce the duration of the pathology.

Amoxiclav or Flemoklav

Flemoklav is considered a fairly common analogue of amoxiclav. It can be found in almost every pharmacy. This remedy is a structural analogue of amoxiclav, since it contains the same ingredients - amoxicillin trihydrate and clavulanic acid.

Flemoklav can be used for infectious lesions of the respiratory system - bronchitis or pneumonia. It can also be used to treat skin pathologies and infections of the pelvic organs.

Amoxiclav or Flemoxin Solutab

When choosing amoxiclav or flemoxin solutab, it is worth considering that the second remedy includes only amoxicillin. Its scope is smaller, since amoxiclav additionally contains clavulanic acid.

Answering the question what to choose - amoxiclav or flemoxin, it should be noted that both substances are included in the category of penicillins. They are often used for bacterial infection of the respiratory system.

Practice shows that flemoxin very successfully copes with sinusitis, bronchitis, acute non-purulent otitis media. It can also be safely used for tonsillitis and bronchopneumonia. The tool is safe, and therefore it is often prescribed even to young children.

Amoxiclav or oxamp - comparison

Comparing amoxiclav and oxamp, it must be taken into account that the drugs have different active substances. So, oxampa contains oxacillin and ampicillin. This remedy is successfully used for infections of the respiratory system, lesions of the skin and pelvic organs. It is also often used for preventive purposes.

Contraindications include high sensitivity to the components of the drug, mononucleosis and lymphocytic leukemia. It is important to consider that the substance can provoke the development of dysbacteriosis, skin rashes, allergies, leukopenia.

Amoxiclav or amoxivan

Amoxiclav is similar in composition to amoxiclav. Therefore, it can be safely used for infectious skin lesions, pathologies of ENT organs, inflammatory processes in the respiratory organs.

Also included in the indications infectious diseases urinary system. Apply the remedy for prophylactic purposes after surgery.

At the same time, amoxivan has many contraindications. These include colitis, stomatitis, allergies. Also, the substance can affect the nervous and circulatory systems.

Amoxiclav or fibell

Fibell also belongs to the penicillin group and is highly effective. It can be used to treat various infectious pathologies. The tool has the same side effects as all other analogs of amoxiclav.

To achieve the desired results, it is very important to strictly follow the instructions. Before starting the use of the drug, it is advisable to consult a doctor.

Amoxiclav or tazocin

Tazocin contains other active ingredients, namely tazobactam and piperacillin. The medicine should be used in the presence of various infectious diseases - respiratory, genitourinary or circulatory systems.

The action of tazocine is aimed at suppressing complex infectious and inflammatory processes. However, the substance has a large number of side effects. Therefore, before starting therapy, you should consult a doctor.

Amoxiclav or bactoclav

Bactoclav is considered a fairly common remedy, which is classified as a semi-synthetic antibiotic. The composition of these substances are identical. Bactoclava contains the same ingredients - amoxicillin and clavulanic acid.

Usually, this substance is prescribed for severe infectious lesions of the respiratory tract, skin, and genitourinary system. Side effects and contraindications for these drugs are also the same.

Amoxiclav is considered very effective tool which helps to cope with infectious pathologies. In this case, quite often there is a need to choose inexpensive analogues. To achieve a good result, before starting therapy, you should consult a doctor.

And moxiclav is an effective combined antibiotic of the penicillin series, which is used in otolaryngology, gynecology, and maxillofacial surgery. The drug has a wide spectrum of antibacterial action against penicillin-sensitive bacterial strains, of which more than forty are known.

In pharmacies there are analogues of Amoxiclav cheaper, which can be purchased by prior agreement with the doctor. Also, replacement will be required in case of individual intolerance to the auxiliary components of silicon dioxide, magnesium stearate, crospovidone.

Before choosing an analogue drug, it is necessary to clarify its dosage, frequency and duration of use. It is not uncommon for a cheaper medicine to be taken longer according to the instructions, thus the price difference does not justify itself, and sometimes it can cost more.

The action of Amoxiclav is due to the active components that make up its composition:

  • Amoxicillin is a substance with a wide antibacterial action, which is classified as a semi-synthetic penicillin.
  • clavulanic acid is able to ensure the resistance of amoxicillins to the effects of special substances that produce pathogenic microorganisms. This component is characterized by its own mild antibacterial activity.

The drug is active against gram-positive aerobes, gram-negative bacteria, anaerobic gram-positive microorganisms, gram-negative anaerobes.

After oral administration, both active substances show rapid absorption, which is not affected by food intake.

Achievement of the maximum concentration is observed 60 minutes after the use of the drug.

The active substances are distinguished by the following characteristics:

  • They are unable to cross the blood-brain barrier.
  • Distributed in the lungs, uterus, ovaries, muscle tissue, tonsils, middle ear, pleural, synovial and peritoneal fluid, liver, prostate, gallbladder, saliva, bronchial secretions.
  • They can cross the placental barrier and be excreted in breast milk.

The half-life is up to 90 minutes.

Indications for use

The list of indications is wide. According to the instructions for use, the drug is used in the diagnosis of:

  • Chronic and acute sinusitis.
  • pharyngeal abscess.
  • Otitis media.
  • Inflammation of the lungs.
  • Tonsillitis.
  • Pharyngitis.
  • cholecystitis.
  • Cholangitis.
  • Abscesses of the mammary glands.
  • Odontogenic infections, including periodontitis.
  • Connective and bone tissue infections.
  • Gonorrhea, including those provoked by exposure to gonococcal infection.
  • Chronic and acute bronchitis accompanied by the addition of superinfection.
  • Infections of the urinary system.
  • Mixed infection caused by exposure to gram-positive and gram-negative microorganisms.

The drug is also prescribed to prevent the development of complications after surgical interventions affecting the pelvic organs, abdominal cavity, kidneys, heart, bile ducts.

Dosage table for adults and children

Tablets should be taken at the beginning of a meal with plenty of liquid. The dosage is selected taking into account the age of the patient and the therapeutic result provided. The course of admission is up to 2 weeks.

Contraindications and side effects

Amoxiclav is not prescribed for:

  • Individual intolerance to active or auxiliary components, as well as penicillins, cephalosporins and other beta-lactam antibiotics.
  • Infectious mononucleosis and lymphocytic leukemia.
  • A history of cholestatic jaundice or other liver dysfunction associated with the use of amoxicillin and clavulanic acid.
  • Special care is required in the treatment of lactating women, patients with kidney failure, severe renal dysfunction, a history of pseudomembranous colitis.

The drug can provoke the development of mild, transient adverse reactions from the digestive tract, nervous, urinary and hematopoietic systems, allergies. In rare cases, superinfection may develop.

The cost of the drug

The price of Amoxiclav in January 2018 is:

  • Tablets 375 mg (250 + 125 mg), 15 pcs.- from 200 rubles, 625 mg (500+125mg), 14 pcs. – from 360 rubles, 1000 mg (875 + 125 mg), 14 pcs.- from 420 rubles.
  • Soluble tablets 625 mg, 14 pcs. - from 380 rubles, 1000 mg, 14 pcs. - from 440 rubles.
  • Tablets 2X 625 mg, 15 pcs. - from 360 rubles.
  • Powder for the preparation of a suspension 125 + 31.25 mg, 100 ml - from 120 rubles, 250 + 62.5 mg, 100 ml - from 280 rubles.
  • Powder for solution for injection, 5 pcs. - from 840 rubles.

List of cheaper analogues of Amoxiclav

As already mentioned, the current active substances Amoxiclav are amoxicillin (the main active ingredient) and clavulanic acid (necessary to protect amoxicillin from the effects of toxic substances produced by bacteria).

From this it follows that the best replacement for the original drug will be a drug that copies its structure, in other words - containing both of these substances.

The list of cheaper structural analogues of Amoxiclav is as follows:

  • Arlette - from 219 rubles;
  • Rapiclav - from 255 rubles;
  • Medoklav - from 280 rubles;
  • Ecoclave tab - from 286 rubles;
  • Flemoklav Solutab - from 285 rubles;
  • Panclave from - 280 rubles;
  • Klamosar - from 360 rubles.

Of them Russian analogues this is:

  • Arlet is manufactured by Sintez AKOMP.
  • Ecoclave is an analogue of Amoxiclav in tablets, as well as in the form of a powder for the preparation of a suspension from Avva Rus.

Both drugs differ in budgetary cost and can be used as a replacement for Amoxiclav by prior agreement with the doctor.

Below we consider effective substitutes original drug according to the principle of impact on the body and containing only one active substance - amoxicillin.

Augmentin or Amoxiclav - which is better

Agumentin is a drug similar to Amoxiclav in composition, dosage, and spectrum of pharmacological activity.

The cost of a course of treatment with Augmentin will cost about 5-10% more. Both drugs are available in several dosage forms, which allows you to choose the right tool for the treatment of both adults and children.

Indications, contraindications, possible adverse drug reactions are similar, so Augmentin can be used as a replacement for Amoxiclav.

Particular attention should be paid to the dosage of drugs: quantitative content active components substitute should be exactly the same as the dosage recommended by the doctor.

Amoxiclav or Amoxicillin - which is better

Amoxicillin is a one-component drug, while Amoxiclav additionally contains clavulanic acid, which enhances the stability of amoxicillin and expands the spectrum of action of the drug.

A suitable drug is selected taking into account the pathogen that provokes the pathological process.

Amoxicillin may be less effective against a number of pathogens, most of which have developed resistance to this substance.

Therefore, the drug is practically not used to treat staphylococcal infections, but is prescribed to eliminate streptococci. Amoxiclav has a higher cost than Amoxicillin.

Sumamed or Amoxiclav

Sumamed and Amoxiclav are drugs with different active ingredients.

Sumamed contains azithromycin, a macrolide antibiotic, which has similar indications for use, but a different mechanism of pharmacological action.

Both drugs can provoke the development of dyspeptic disorders. Amoxiclav is more likely to cause development allergic reactions and may also have a negative effect on the central nervous system.

Among the advantages of Sumamed, a shorter course of treatment can be noted (in some cases, a single or three times the use of tablets is sufficient).

This is due to the ability of the active substance to accumulate in peripheral tissues and penetrate directly into the focus of the inflammatory reaction. The cost of Sumemad exceeds the price of Amoxiclav.

Amoxiclav or Flemoxin Solutab

Flemoxin Solutab is often offered in pharmacies as a drug similar to Amoxiclav. These drugs are not exact structural analogues, since Flemoxin contains only amoxicillin.

Flemosin solutab is presented in the form of soluble tablets, Amoxiclav has a similar release form.

However, the original has a more extensive list of indications for use, according to reviews, and is easier to tolerate by some categories of patients.

What is better Azithromycin or Amoxiclav

Despite the differences in the chemical structure of the active substances, both drugs have a similar list of indications for use.

Amoxiclav begins to act faster: after 60 minutes, while azithromycin may take up to 120 minutes.

In some cases, the doctor may prescribe the combination of these drugs, for example, during complex therapy hospital pneumonia.

Unlike Amoxiclav, azithromycin-based drugs are active against:

  • Mycoplasma, provoking, atypical pneumonia.
  • Koch's sticks, which cause tuberculosis.
  • Certain types of legionella.

In the event that resistance of pathogenic microorganisms to amoxicillin is observed, azithromycin may become the drug of choice.

Suprax or Amoxiclav

Amoxiclav and Suprax (an antibiotic of the cephalosporin series) are antibacterial drugs that are different in composition and mechanism of action.

Suprax is effective in the treatment of patients with chronic obstructive pulmonary disease, more convenient to use. It is one of the most modern, effective antibiotics, which can be considered as a substitute for the ineffectiveness of Amoxiclav.

The advantage of Amoxiclav is the ability to use the drug in the treatment of children under one year old.

Flemoclav or Amoxiclav

Both drugs are equivalent replacements for each other, and are almost the same in price. When prescribing an analogue, one should not forget about coordinating the dosage necessary for the patient.

Klacid or Amoxiclav

Klacid is a drug based on clarithromycin, which is well tolerated by patients, is rapidly distributed in tissues and body fluids, accumulating to a greater extent in the tissue area.

May be used in the treatment of patients with impaired renal function. Unlike Amoxiclav, it has a more convenient dosage regimen and a wider spectrum of action.

Macrolides can provoke the development of adverse reactions in the form of sleep disturbances, increased anxiety, irritability, and hearing impairment. Both drugs have similar indications for taking, Klacid is additionally prescribed to patients with peptic ulcer stomach.