Sulfacyl sodium eye drops in Latin. Medicines guide Sulfacyl sodium (sulfacetamide)
Latin name: Sulfacylum-natrium
ATX code: S01AB04
Active substance: Sulfacetamide
Manufacturer: Synthesis, Russia, etc.
Pharmacy leave condition: Without recipe
Price: from 50 to 100 rubles.
"Sulfacyl-sodium", or "Albucid" (other tradename) - a solution with an antibacterial effect. Used in ophthalmology.
Indications for use
"Sulfatsil" is applied externally, against infectious eye lesions. These include:
- Conjunctivitis
- Blepharitis
- Corneal ulcer with purulent lesion
- Keratitis
- Gonorrheal eye lesions in children (20% solution) and adults (30% solution)
- Blennorrhea - treatment and prevention of the disease in newborns (30%).
Doctors often prescribe cold medicine for children.
Compound
One ml of the solution contains 200 or 300 mg of sulfacetamide (20% and 30%, respectively). Additional substances: thiosulfate, hydrochloric acid solution, injection liquid.
Medicinal properties
"Sulfacyl-sodium" (or "Albucid") exhibits moderate bacteriostatic properties against gram-positive and gram-negative bacteria. These bacteria include: pneumococci, chlamydia, streptococci, actinomycetes, gonococci, E. coli.
The aqueous solution is slightly alkaline, so it can be safely used as eye drops. Contact with the conjunctival sac of the eye will not cause any harm. Predominantly albucid for the eyes acts locally on the affected conjunctiva, but part of the active substance is absorbed into the body. The mechanism of action of "Sulfacyl-sodium" is due to the opposition to para-aminobenzoic acid and the binding of dihydropteroate synthetase. This process leads to disruption of the production of tetrahydrofolic acid, which is mainly involved in the synthesis of purine and pyrimidine bases. Due to this mechanism of action, the DNA and RNA of the cells of pathogenic bacteria are disrupted, the process of their reproduction stops.
The average price is from 50 to 100 rubles.
Release forms
1) In a dropper tube, there is a solution of 20% and 30%, 1.5 ml each. The box contains 2 tubes. Easy to use for eye damage. The liquid is transparent, strongly stings the eyes, it is better not to apply on lenses
2) A solution of albucid 20% or 30% with methylcellulose 10% is available in 5 ml or 10 ml vials. The packaging of the drug contains only one vial inside
3) 30% solution of albucid with metabisulphite, available in 5 ml and 10 ml vials.
Mode of application
Eye drops of 1.5 ml can be applied to the conjunctival sac every 4 hours, 1-2 drops. To avoid neonatal blennorrhea, you can drip 2 drops every two hours.
Albucid with methylcellulose and metabisulfate is also used as eye drops. They are used not only for eye damage. They are often prescribed for the common cold in children and adults. From the common cold, the drug helps for the reason that it has a drying effect. Sulfacil-sodium is especially effective in the nose, when the runny nose has become chronic and the snot has acquired a green tint. A drug is dripped into the ear for the treatment of otitis media or with purulent sore throat, if there is a complication in the ear canal.
During pregnancy and breastfeeding
Use during pregnancy did not adversely affect the fetus. Therefore, you can use this drug, but only as directed by your doctor. During the period breastfeeding and simultaneous application eye drops"Albucid" or "Sulfacyl-sodium", no negative changes in health were found in newborns.
Contraindications
The reasons for refusing to use drops include individual intolerance.
Precautionary measures
Do not wear lenses while taking the drug. If there is a strong need for lenses, then you can wear them only 15 minutes after applying the medication.
People with hypersensitivity to diuretics may also be sensitive to albucid.
Interaction with other drugs
When applied topically, the drug is incompatible with silver salt. With novocaine and diacaine, the effect on the body is reduced. Enhances the effect of anticoagulants of indirect action.
Side effects
Sometimes itching, redness and irritation of the eyes can be observed.
Overdose
In case of overdose, severe eye irritation occurs. In this case, you need to stop using the medication.
Terms and conditions of storage
Shelf life - 2 years. After opening the bottle, use the contents for no more than 4 weeks. Store at a temperature of +2 - +8 degrees in the refrigerator.
Analogues
analogues with identical active substance: Sulfacyl sodium-Dia, Sulfacyl sodium-Solopharm.
The only analogue with another active ingredient, but a similar effect:
Irbitsky KhPZ OAO, Russia
Price from 1200 to 1500 rubles.
The active substance, sulfapyridazine, is available as an eye film. Effective against trachoma, conjunctivitis and keratitis.
pros
- The drug has a powerful effect
- Dissolves well
Minuses
- Weakly used drug
- May cause burning in the eye
- Expensive.
"Sulfacyl sodium-Dia" and "Sulfacyl sodium-Solopharm"
Diapharm CJSC/SOLOpharm, Russia
Prices from 75 to 95 rubles.
The drugs are available in the form of eye drops. Indications - blenorrhea, infectious lesions of the eyes.
pros
- Fight disease effectively
- Suitable for babies
Minuses
- Pinch the mucosa
- It is not recommended to wear lenses during the period of use of the drug.
| Sulfacyl sodium
Analogues (generics, synonyms)
Sulfacetamide sodium, Albucid-sodium, Sulfacil soluble, Acetopt, Almocetamide, Octsetane, Oftalimide, Prontamide, Sebizon, Sodium sulfacetamide, Sulfaprocul
Recipe (international)
Rp.: Sol. Sulfacyli natrii 20% - 10.0 ml.
D.S. 2 drops 4 times a day.
pharmachologic effect
antibacterial agent for local application in ophthalmology, a sulfanilamide derivative. It has a wide spectrum of antimicrobial activity. It has a bacteriostatic effect. The mechanism of action is associated with competitive antagonism with PABA and competitive inhibition of dihydropteroate synthetase, which leads to disruption of the synthesis of tetrahydrofolic acid, which is necessary for the synthesis of purines and pyrimidines.
Sulfacetamide is active against Gram-positive and Gram-negative bacteria (including pathogenic cocci, Escherichia coli), Chlamydia spp., Actinomyces spp.
Mode of application
For adults: Apply 2-3 drops to the lower conjunctival sac of each eye 5-6 times / day.
For the prevention of blennorrhea in newborns, 2 drops of the solution are instilled into the eyes immediately after birth and 2 drops after 2 hours.
Indications
Purulent ulcers of the cornea
- Conjunctivitis, blepharitis
- Gonorrheal eye diseases in newborns and adults
- Prevention of blennorrhea in newborns.
Contraindications
Hypersensitivity to the components of the drug and sulfonamides in history.
Side effects
Local reactions: itching, redness, swelling.
Release form
Eye drops 20%: vial-drip. 5 ml or 10 ml
Eye drops 20% transparent, colorless or slightly colored.
1 ml:
sulfacetamide 200 mg.
5 ml - polymeric dropper bottles (1) - packs of cardboard.
10 ml - polymeric dropper bottles (1) - packs of cardboard
ATTENTION!
The information on the page you are viewing was created for informational purposes only and does not promote self-treatment in any way. The resource is intended to familiarize healthcare professionals with additional information about certain medicines, thereby increasing their level of professionalism. The use of the drug "" without fail provides for a consultation with a specialist, as well as his recommendations on the method of application and dosage of the medicine you have chosen.
The active substance of the drug - sodium sulfacetamide monohydrate . Additional ingredients: sodium thiosulfate, purified water, hydrochloric acid.
Release form
In pharmacies, you can find Sulfacil Sodium eye drops 20%, 30%, as well as powder in a package.
pharmachologic effect
The medicine has antimicrobial properties.
Pharmacodynamics and pharmacokinetics
Pharmacopoeia indicates that the formula Sulfacyl Sodium is CsHgSaNaOsS-b^O. INN – Sulfacetamide . The Latin recipe will contain the name Sulfacylum-natrium.
Eye drops inhibit absorption PABC and also interfere with the synthesis PABA-containing growth factors microorganisms.
The medicine is characterized antibacterial properties. It acts on streptococci , gonococci , coli , chlamydia , pneumococci , actinomycetes .
An aqueous solution of Sulfacyl Sodium has a slightly alkaline reaction, which allows it to be instilled into conjunctival sac eyes.
Indications for use
Eye drops are used for gonorrheal eye diseases, conjunctivitis , blennore , purulent ulcers of the cornea, blepharitis and other eye diseases. The drug can be used by both children and adults, including for the purpose of prevention blennorey in babies. When purulent processes it stops them and accelerates the healing of the cornea.
Prescribed for therapy streptoderma and staphyloderma , infections provoked coli .
The medicine can be used orally in case of colibacillary infections urinary tract, mastoiditis , puerperal sepsis and others infectious diseases .
Contraindications
Cannot be applied this remedy with hypersensitivity to its components.
Side effects
In some cases, when taking the drug, tissue irritation, including redness, edema century and itching . When using the medicine inside, it is possible allergy and dyspeptic disorders .
Instructions for use Sulfacyl Sodium (Method and dosage)
For those who are shown Sulfacyl Sodium eye drops, the instructions for use report that instillations should be carried out in conjunctival sac . For adult patients, a dosage of 1-2 drops is prescribed. The agent is applied 5-6 times a day (every 4-8 hours). AT childhood shows a solution of 10 percent and 20 percent. To prevent the development blennorey immediately after birth, babies are instilled with 2 drops of the drug, and then 2 drops every 2 hours.
The drug can also be used in vaseline-based ointments 10-30% in case of blepharitis and eczema eyelid skin.
Instructions for use Sulfacyl Sodium indicates that the duration of therapy directly depends on the severity of the disease. It is not recommended to use the medicine for a longer period without consulting a specialist.
When gonorrheal eye diseases are prescribed combination therapy . A 30% solution is instilled or the affected area is powdered with powder, in addition, the drug is taken by mouth.
infected wounds treated with powder.
The maximum single dosage for adults inside is 2 g, the maximum daily dose is 7 g.
Before the first use of the drops, the cap is screwed to the end. spike on inside pierces a hole in the membrane. Before use, you need to hold the bottle a little in the palm of your hand to heat the product to body temperature. The cap is unscrewed and after light pressure on the body of the vial, the solution is instilled into the eyes. Then the bottle should be closed again.
Overdose
In case of an overdose, redness, swelling of the eyelids, itching are possible. Then continue the use of a lower concentration or completely cancel the drug.
Interaction
If you need to take other drugs in combination with Sulfacyl Sodium, you should consult your doctor.
Bacteriostatic the effect of the drug is reduced when combined with Novocaine , Anestezin and Dekain . And its toxicity increases when interacting with Difenin , salicylates and para-aminosalicylic acid . When used in conjunction with indirect anticoagulants increase in their specific activity is possible.
Do not use drops together with salts of some alkaloids, with products including silver salts, with zinc sulfate, as well as with acids and substances that have an acid reaction.
Terms of sale
The drug is sold without a prescription.
Storage conditions
It is necessary to keep the drug in a dark place. The optimum temperature is 15-25°C.
Best before date
2 years. After the first use, keep the product for no longer than 4 weeks.
Analogues
Coincidence in the ATX code of the 4th level:
The following analogues of the drug are known: Albucid , Acetopt , Oftalemid , Sebizon , Sulfaproculus , Sulfacyl , Sulfacyl soluble , Almocetamide , Octzetan , Prontamide , sobizon , Sulfacetamide Sodium , Sulfacyl Sodium-DIA .
Albucid and Sulfacyl Sodium
What is more efficient Albucid or Sulfacyl Sodium, is often asked on the forums. Experts answer that in fact they are synonyms. In this way, Albucid This is Sulfacyl Sodium. This drug is also available in the form of eye drops and is used for diseases provoked by streptococci , pneumococci , gonococci . However, relatively recently Albucid and Sulfacyl Sodium began to be used for instillation into the nose.
Sulfacyl sodium for children
Sulfacyl Sodium for children is used in a dosage of 2-3 drops (20% solution). The child should be in the "sitting" or "lying" position. You should gently push the eyelids and drip the medicine. It is recommended to start from the place where the inflammation is less pronounced.
When acute otitis media the drug is instilled into the ears. It can be diluted in boiled water 2-4 times.
newborn
Medicine for newborns, as a rule, is instilled immediately after birth to prevent development blennorey .
In addition, Sulfacyl Sodium is often used in the nose of the baby. The doctor prescribes this remedy for prolonged rhinitis, especially when it comes to bacterial infection . It should be borne in mind that if it gets into the nose, the drug can cause a burning sensation, because of which the child begins to act up.
During pregnancy (and lactation)
After consulting a doctor, the medicine can be used for pregnancy . It can also be used during breastfeeding . Apply the drug for pregnancy and lactation necessary in doses prescribed by a specialist. It is not recommended to increase the dosage on your own.
Means used in ophthalmology. Antimicrobial agents. Sulfonamides. ATS code: S01AB04.
pharmachologic effect
Sulfacyl sodium is a broad-spectrum sulfanilamide antimicrobial drug. Has a bacteriostatic effect.
Active against gram-positive and gram-negative cocci, Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringens, bacillus anthracis, Corynebacterium diphtheriae, Yersiniapestis, Chlamydia spp., Actinomyces Israel, Toxoplasma gondii.
Perhaps the development of resistance to sulfacetamide.
Indications for use
As part of complex therapy. Infectious and inflammatory eye diseases caused by bacteria sensitive to the drug: conjunctivitis, blepharitis, purulent corneal ulcers, gonorrheal eye diseases in adults. It is not recommended to use sodium sulfacyl for viral or fungal eye infections. It is only used to treat infections caused by bacteria.
Dosage and administration
For the treatment of conjunctivitis in adults, 1-2 drops of the solution are instilled into the conjunctival sac every hour, in the next 3-4 days - 5-6 times a day.
For the treatment of blepharitis in adults, the frequency of instillations in the first days is up to 6-8 times and decreases to 3-4 times a day as the condition improves, the duration of treatment is 3-5 days.
For the treatment of a purulent corneal ulcer as part of complex therapy in the form of instillations - 5-6 times a day for 5-7 days.
In the treatment of gonorrheal and chlamydial eye diseases in adults as part of complex therapy - 1-2 drops 5-6 times a day for 4-6 weeks. With positive dynamics against the background of ongoing treatment, the number of instillations of drops is reduced in each subsequent week.
Dosage form containing 300 mg/ml active substance, preferably used in adults.
Before use, carefully read this section and follow the steps shown below in the text and in Figures 1-6 in sequence.
Take the bottle out of the package (picture 1). Place the scissors at an angle of 45 degrees to the cap, prying up its lower edge, with an upward movement, remove the aluminum cap together with the rubber cap (Figure 2). Remove the dropper from the package and put it tightly on the vial (Figure 3). Turn the vial upright to remove the air bubble and wait a few seconds. In the case of a large bubble, return the vial to its original position, and then slowly repeat the action by gently tapping the bottom of the vial (Figure 4). Make an instillation by pressing the index finger and thumb on the pipette (Figure 5). Turning the vial over, close the pipette with a special stopper (Figure 6).
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Side effect
In some cases, irritation of the tissues of the eye (redness, itching, swelling of the eyelids, burning, lacrimation), allergic reactions are possible.
Unwanted action message
If you experience any side effects, tell your doctor about it. This also applies to any side effects, whichwhich are not listed in this leaflet.insert. You can also report adverse reactions to the information database on adverse reactions (actions) to medicines, including reports of ineffectiveness medicines, identified on the territory of the state (UE "Center for Expertise and Testing in Healthcare M3 RB",). By reporting adverse reactions, you help to get more information about the safety of the drug.
Contraindications
Hypersensitivity to sulfonamides or excipients in history. Overdose
Symptoms: with frequent use of the drug, redness, itching, swelling of the eyelids, significant irritation of the mucous membrane of the eye is possible.
In this case treatment continue with a solution of sulfacyl at a lower concentration, if necessary, cancel the drug and prescribe symptomatic treatment.
Precautionary measures
For topical use only. Cannot be injected.
Rarely, fatal cases have been reported due to the occurrence of severe reactions to sulfonamides, including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatonecrosis, agranulocytosis, aplastic anemia and others. pathological changes blood systems.
Sensitization to sulfonamides may occur with repeated use, regardless of the route of administration. Sensitization to sulfonamides has been noted in people with no history of hypersensitivity to sulfonamides. At the first sign of hypersensitivity, skin rash or other serious adverse reactions the use of the drug should be discontinued.
Patients with hypersensitivity to furosemide, thiazide diuretics (hydrochlorothiazide), sulfonylurea derivatives (glibenclamide) or carbonic anhydrase inhibitors (diacarb) may have hypersensitivity to sulfacyl.
Possible overgrowth of microorganisms insensitive to sulfacetamide, as well as fungal flora.
The antibacterial activity of the drug is reduced in the presence of high concentrations of para-aminobenzoic acid in the presence of a large number purulent discharge.
It is necessary to stop therapy in case of allergy symptoms, as well as with increased pain and other signs of an infectious-inflammatory process, an increase in the amount of purulent discharge.
Children. This dosage form do not use in children.
Application during bpregnancy and lactation
It is not known what effect sodium sulfacyl may have on the fetus. It is not recommended to use sodium sulfacyl for pregnant women without consulting a doctor. It is not known whether sodium sulfacyl penetrates into breast milk. It is not recommended to use sodium sulfacyl for nursing mothers without consulting a doctor.
Influence on the ability to drive vehicles and otherpotentially dangerous mechanisms
Care must be taken when driving, operating industrial machinery, or performing other hazardous work. Sulfacyl sodium may cause visual impairment. If you experience blurred vision, refrain from hazardous activities.
Interaction with other drugs
When used together with novocaine, dicaine, anesthesin, the bacteriostatic effect of the drug is reduced.
Difenin, PASK, salicylates increase the toxicity of sodium sulfacyl.
When using sodium sulfacyl with indirect anticoagulants, the specific activity of the latter increases.
Holiday conditions
Without recipe.
Manufacturer
RUE "Belmedpreparaty"
Republic of Belarus, 220007, Minsk,
st. Fabriciusa, 30, t./fa.: (+375 17) 220 37 16,
e-mail: [email protected]
