How to take Almagel green. Enveloping products

The action of the drug is based on the long-term neutralization of continuously released gastric juice, reducing the concentration of hydrochloric acid in it to optimal values.

Due to these properties, the drug is used in the treatment of many diseases of the gastrointestinal tract.

1. Instructions for use

The properties of Almagel are due to its constituent components:

• Aluminum hydroxide neutralizes hydrochloric acid, forming chloride.
• Magnesium hydroxide, along with acid neutralization, counteracts the constipating properties of aluminum chloride.
• Benzocaine, which is part of Almagel A, has a local analgesic effect.

In addition to the main antacid properties, Almagel has gastroprotective, adsorbing and enveloping qualities. D-sorbitol in the composition of the drug has a laxative effect and enhances bile secretion.

The drug does not cause a sharp change in the acidity of the stomach in the direction of an alkaline reaction, and does not affect the pH of the blood, does not provoke the formation of stones in the biliary tract and does not disturb the electrolyte-water balance.

Almagel reacts with hydrochloric acid of the stomach, leading to a decrease in the digestive capacity of gastric juice, without causing its secondary hypersecretion. Additionally, it has an enveloping and adsorbing effect, reducing damage to the mucous membrane. After administration, the drug begins to act after 3-5 minutes, and the effect lasts about 70 minutes.

Indications for use

Almagel is used for the following diseases associated with high acidity:

• Enteritis, duodenitis.
• All forms of gastritis.
• Gastroesophageal reflux disease.
• Post-resection gastritis.
• Pain and discomfort in the abdomen after excessive consumption of coffee, alcohol, medicines, nicotine, wrong diets.
• Fermentative and putrefactive dyspepsia.
• Gastroanastomosis with reflux.

Mode of application

Before use, the bottle with the drug is shaken and taken before meals for 10-15 minutes, after which 15 minutes. do not drink liquid.

If it is necessary to obtain a symptomatic antacid effect, Almagel is taken in the recommended doses after 45-60 minutes. after meals and shortly before sleep.

With insufficient effect, it is permissible to take up to 3 teaspoons, but not more than the maximum allowable daily allowance- 16 spoons.

Maximum doses should not be continued for more than 2 weeks. The course of treatment with usual doses is 2-3 months.

Depending on the form of Almagel, the scheme for taking it is as follows:

• Reception as prescribed by a doctor 1-3 tsp, based on the severity of the case;
• For preventive purposes - 1-2 tsp. in a day;
• Children under 10 years old - 1/3 of the adult dose, from 10 to 15 years old - ½ of the adult dose;
• Treat diseases with nausea, vomiting, pain in the abdomen begin with Almagel A, and when they disappear, they switch to Almagel.

2. Almagel Neo:

• Take 2 scoops 4 times a day and at bedtime. A single dose in some cases can be increased to 4 tablespoons, but not more than 12 per day;
• For children over 10 years old, the dosage is determined by the doctor (usually ½ of the adult dose).

3. Tablets Almagel:

• One-time admission rate - 1-2 pcs. no more than 6 times a day. Optimal time use - 1-2 hours after eating and at bedtime. The standard course of admission is 10-15 days;
• Tablets are prescribed for children from the age of 12.

Release form, composition

Almagel is available in the form of a suspension and tablets, while there are several options for suspensions:

• Almagel(packed in a green box) - consists only of the main components (aluminum and magnesium hydroxide gel).
• Almagel A (packed in a yellow box) - along with the basic components, it includes an analgesic (benzocaine).
• Almagel Neo(packed in a red box) - contains basic components and simethicone, which eliminates gases.

The drug is poured into 170 ml bottles complete with a measuring spoon, Neo Option can be produced in 10 ml sachets. Tablets are packed in boxes of 12 and 24, marked with the letter T.

The qualitative composition of all forms of Almagel is as follows:

1. Almagel:

• Active ingredients: aluminum hydroxide, magnesium hydroxide;
• Excipients: methyl, butyl and propyl parahydroxybenzoate, sodium saccharin, ethanol, sorbitol, hydroxyethyl cellulose, lemon oil, water.

• Active ingredients: algeldrate (aluminum hydroxide in the form of a gel), magnesium hydroxide, benzocaine;
• Auxiliary components: similar to Almagel.

3. Almagel Neo:

• Active ingredients: aluminum hydroxide in the form of a gel, magnesium hydroxide and simethicone;
• Excipients: perhydrol 30%, citric acid monohydrate, sorbitol, propylene glycol, sodium saccharinate, macrogol 4000, ethanol 96%, hyetellose, ethyl parahydroxybenzoate, orange flavor, water.

4. Almagel T (tablet 0.5 g):

• Active ingredients: aluminum and magnesium hydroxide;
• Excipients: magnesium stearate, mannitol, sorbitol, microcrystal. cellulose.

Interaction with other drugs

When taken simultaneously, Almagel is able to reduce the therapeutic effect of tetracycline antibiotics, digitalis glycosides, ciprofloxacin, isoniazid, indomethacin, beta-blockers, phenothiazines, ketoconazole.

2. Side effects

After taking all types of Almagel, the following side effects may occur:

• Distortion of taste sensations.
• Nausea, vomiting.
• Stomach cramps.
• Drowsiness.

The maximum dose of the drug in combination with a lack of phosphorus intake from food causes manifestations of phosphorus deficiency, activation of calcium excretion in the urine and the development of osteomalacia.

Contraindications

Contraindications for taking the drug are as follows:

• Hypersensitivity to the components of the drug.
• Alzheimer's disease.
• Severe pathologies of kidney function.
• At the age of up to 1 month, up to 10 years Almagel Neo.

During pregnancy

During pregnancy, Almagel is not taken longer than 3 days. When breastfeeding, Almagel is not taken.

3. Terms and conditions of storage

Almagel is stored in a cool place without access to light at tо 1-25оС (optimally at 5-15оС) for 5 years. Freezing of the drug is unacceptable.

4. Price

Depending on the geographical location of the pharmacy and the trade margin, Almagel has the following price:

Average price in Russia:

Average cost in Ukraine

• Almagel - 32-39 UAH;
• Almagel A - 31-47 UAH;
• Almagel Neo - 47-64 UAH;
• Tablets - 32-41 UAH.

5. Analogues

Drugs similar in action to Almagel are the following:

• Maalukol;

Video on the topic: Almagel

6. Reviews

Thanks to the long-term release of Almagel, the network has accumulated about him a large number of reviews. Many people who took the drug speak positively about it, citing its high efficiency and long-term action to eliminate symptoms.

Almagel®, oral suspension - polyethylene terephthalate bottle (bottle) 170 ml with a measuring spoon (spoon), cardboard pack 1- EAN code: 3800009121082- No. P N012742 / 01, 2010-02-26 from Balkanpharma-Troyan (Bulgaria)

Latin name

Active substance

ATX

Pharmacological group

Nosological classification (ICD-10)

Composition and form of release

5 ml of suspension for oral administration contain aluminum hydroxide 300 mg (equivalent to 200 mg aluminum oxide), magnesium hydroxide 100 mg - in 170 ml plastic bottles complete with a dosing spoon, 1 bottle in a cardboard bundle.

Characteristic

Suspension of white or slightly grayish color with a characteristic sweetish taste and smell of lemon.

pharmachologic effect

Neutralizes hydrochloric acid and reduces the activity of pepsin, gastric juice, protects the gastrointestinal mucosa from damaging effects.

Pharmacodynamics

It is evenly distributed over the gastric mucosa and provides long-term gastroprotection. It has buffer-antacid properties: between doses, the pH of gastric juice remains from 4-4.5 to 3.5-3.8. Sorbitol has a choleretic and mild laxative effect. The therapeutic effect appears after 3-5 minutes and lasts 70 minutes.

Pharmacokinetics

Practically not absorbed from the gastrointestinal tract.

Indications for Almagel®

Peptic ulcer of the stomach and duodenum (acute phase), acute or chronic gastritis against the background of normal or increased secretion (acute phase), reflux esophagitis, diaphragmatic hernia, duodenitis, enteritis, gastrointestinal disorders caused by a violation of the diet, taking medications (NSAIDs, glucocorticoids), drinking coffee or alcohol, smoking.

Contraindications

Hypersensitivity, severe renal dysfunction, Alzheimer's disease, neonatal period, breastfeeding.

Use during pregnancy and lactation

During pregnancy, use no longer than 3 days. At the time of treatment should stop breastfeeding.

Side effects

From the digestive tract: taste disturbance, nausea, vomiting, spasm, pain in the epigastric region, constipation.

From the side of metabolism: hypercalciuria, hypermagnesemia, hypophosphatemia.

Others: drowsiness, osteomalacia, dementia and swelling of the extremities (against the background of chronic renal failure).

Interaction

Reduces the effectiveness of tetracyclines, H2-antihistamines, cardiac glycosides, iron salts, ciprofloxacin, phenothiazines, isoniazid, beta-blockers, indomethacin, ketoconazole, etc. (when administered together, an interval between doses of at least 1-2 hours is recommended).

Dosage and administration

Inside, 0.5 hours before meals (for peptic ulcer of the stomach and duodenum between main meals) and at night, adults 1-3 dosing spoons 3-4 times a day. Maintenance dose - 1 dosing spoon 3-4 times a day for 2-3 months. Preventive therapy - 1-2 dosing spoons.

Children strictly according to the doctor's prescription: up to 10 years old - 1/3 dose for adults, 10-15 years old - 1/2 dose.

The maximum daily dose is 16 dosing spoons, at this dose the duration of treatment is no more than 2 weeks.

Before taking the suspension should be shaken.

In case of a disease accompanied by nausea, vomiting and abdominal pain, treatment begins with Almagel A, and after the disappearance of the listed symptoms, they switch to Almagel.

Overdose

Symptoms: inhibition of gastrointestinal motility.

Treatment: the appointment of laxatives.

Precautionary measures

With prolonged use, it is necessary to ensure sufficient intake of phosphorus with food.

special instructions

With functional disorders accompanied by nausea, vomiting, abdominal pain, treatment begins with Almagel A.

Storage conditions of Almagel®

Keep out of the reach of children.

Shelf life of Almagel®

Last update of the description by the manufacturer

Other options for packaging the drug - Almagel®.

Almagel®, suspension for oral administration - bottle (bottle) 170 ml with a measuring spoon (spoon), cardboard pack 1- EAN code: 3800009120016- No. P N012742 / 01, 2010-02-26 from Balkanpharma-Troyan (Bulgaria) Almagel® , suspension for oral administration - polyethylene terephthalate bottle (bottle) 170 ml with a measuring spoon (spoon), cardboard pack 1- EAN code: 3800009121082- No. P N012742 / 01, 2010-02-26 from Balkanpharma-Troyan (Bulgaria)

Instructions for use:

Pharmacological properties

Almagel is the first antacid drug. Antacids are intended for the treatment of acid-dependent diseases of the gastrointestinal tract by neutralizing the hydrochloric acid contained in the gastric juice. The active component of Almagel, aluminum hydroxide, has become the basis for the production of a number of antacids. Aluminum hydroxide, coming into contact with hydrochloric acid, neutralizes it by forming aluminum chloride. Almagel also contains magnesium hydroxide, which, in addition to neutralizing hydrochloric acid, eliminates the ability of aluminum chloride to provoke constipation. Active application Almagel in medical practice is due to the antacid, enveloping, gastroprotective and adsorbing properties of the drug. Thanks to D-sorbitol, which is part of Almagel, the drug is able to act as a laxative and enhance bile secretion.

The action of Almagel is observed for a long period of time. The drug does not secondarily increase the release of hydrochloric acid and does not cause flatulence, since the regulation of the acidity of hydrochloric acid occurs evenly without the formation of carbon dioxide bubbles. The use of Almagel does not provoke a sharp shift in the pH of the stomach to the alkaline side, does not cause an increase in blood pH, and does not disturb the water-electrolyte balance and does not contribute to stone formation in the urinary tract. The composition of Almagel A also includes benzocaine, which has a pronounced local anesthetic effect in pain syndrome.

Almagel is produced in the form of a gel, which allows the drug to be evenly distributed over the gastric mucosa, thereby providing a more effective and lasting effect. The therapeutic effect begins 3-5 minutes after taking a single dose of the drug and lasts about 70 minutes.

Indications for Almagel's use

Acute gastritis with high acidity;

Peptic ulcer of the stomach and duodenum (period of exacerbation);

Esophagitis;

Enteritis, duodenitis;

food poisoning;

Flatulence;

Hernia of the esophageal opening in the diaphragm;

Abdominal pain or discomfort after excessive intake of nicotine, coffee, alcohol, various medications, dietary disorders.

In the case of the use of non-steroidal anti-inflammatory drugs, it is advisable to use Almagel for prophylactic purposes.

Instructions for use Almagel

This drug is taken exclusively inside, the bottle should be shaken before use. According to the instructions for use, Almagel is prescribed for adults 1-2 teaspoons, with insufficient effect, a single dose is increased to 3 teaspoons. The maximum daily dose of the drug should not exceed 16 teaspoons. Children under 10 years old are prescribed 1/3 of the adult dose, and from 10 to 15 years old - 1/2 of the adult dose. Almagel should be taken 4 times a day 30 minutes before meals and at bedtime. The course of treatment with this drug lasts about 14 days.

The duration of the use of Almagel during pregnancy should not exceed three days.

Therapy should be started with Almagel A if the disease is accompanied by nausea, vomiting and pain. After the disappearance of these symptoms, you should switch to the use of Almagel.

Side effects

Clinical studies have shown that in some cases, the use of Almagel may cause such side effects like vomiting, nausea, taste changes, stomach pain and constipation. When taking high doses of the drug, drowsiness occurs.

Long-term intake of high doses of Almagel with the simultaneous use of food poor in phosphorus can provoke the development of phosphorus deficiency in the body, increased absorption and excretion of calcium in the urine, and the occurrence of osteomalacia.

Contraindications

According to the instructions for use, Almagel should not be prescribed in the following cases:

• with severe impairment of kidney function;
• with Alzheimer's disease;
• children under 10 years old;
• at hypersensitivity to the components of the drug;
• with hypophosphatemia;
• with congenital fructose intolerance.

With caution, the drug is prescribed to lactating women, patients with severe constipation, ulcerative colitis, chronic diarrhea, pain in the stomach of unknown origin.

The expediency of using Almagel during pregnancy is determined by the attending physician.

Additional Information

The shelf life of Almagel is 5 years. It should be stored in a well-closed container in a cool (from 5 to 150C - the optimal storage temperature) and protected from light.

Almagel Neo is one of the types of Almagel, one of the actions of which is aimed at reducing the formation of gases in the intestines. Adsorption of intestinal gases and their absorption by the mucous membrane occurs due to simethicone, which is contained in Almagel Neo. This drug is recommended for diseases of the gastrointestinal tract, accompanied by flatulence.

Almagel is one of the first antacid drugs on the pharmacological market, which has been produced for over 40 years.

This drug has antacid, adsorbent and gastroprotective properties. The medicine is intended for the treatment of peptic ulcer of the stomach and duodenum, acute and chronic gastritis, slit hernia and other diseases of the stomach.

Also used as a mild laxative.

Composition and form of release

All 3 types of Almagel have a neutralizing effect on gastric juice, form a protective layer on the surface of the gastric mucosa. Thus, protecting the inflamed mucosa from the aggressive effects of gastric juice.

Almagel

Composition of active ingredients:

• aluminum hydroxide;
• magnesium hydroxide.

Features of the drug:

aluminum hydroxide- when interacting in the lumen of the stomach with hydrochloric acid of gastric juice, it neutralizes the latter, thereby reducing the acidity of the stomach. Aluminum hydroxide also reduces the secretion of the stomach enzyme - pepsin. This property reduces the aggressiveness of gastric juice.

magnesium hydroxide- by analogy with aluminum hydroxide, it reacts to neutralize hydrochloric acid. Magnesium hydroxide also has a laxative effect, thereby neutralizing the effect of aluminum hydroxide, which can cause slowing of peristalsis and constipation.

Almagel Neo

Composition of active ingredients:

• aluminum hydroxide;
• magnesium hydroxide;
• Simethicone.

What is the difference: this drug contains the same components as Almagel, but it also contains simethicone. Simethicone is a drug that prevents increased gas formation. In diseases of the stomach and duodenum, the entire digestive process is disturbed, which contributes to the activity intestinal microflora and active formation of gases in the intestines.

Almagel A

Composition of active ingredients:

• aluminum hydroxide;
• magnesium hydroxide;
• Benzocaine.

What is the difference: it contains the same components as Almagel, but additionally it contains benzocaine, which has an analgesic (freezing) effect on the mucous membranes. Thanks to benzocaine, it is possible to get rid of soreness caused by inflammation of the mucous membranes of the esophagus, stomach or duodenum.

Indications for use

The drug is mainly prescribed for diseases of the gastrointestinal tract. Among them, the most frequent are:

• peptic ulcer stomach (GU) and peptic ulcer of the duodenum (PUD) - an acute period and a period of exacerbation;
• acute inflammatory disease gastric mucosa (gastritis) with impaired acid-forming function;
• food poisoning with toxins;
• esophagitis - an inflammatory disease of the esophageal mucosa;
• duodenitis - an inflammatory disease of the duodenum;
• enteritis - inflammatory bowel disease;
• hernia in the region of the esophageal opening in the diaphragm;
• flatulence;
• symptomatic treatment of pain and discomfort in the epigastric region, which occur after an error in the diet (alcohol abuse, smoking, addiction to coffee and excessive medication);
• intake for prevention.

The last point would be appropriate in terms of preventing the re-development of ulcers in the gastrointestinal tract against the background of the use of non-steroidal anti-inflammatory drugs and hormones (glucocorticosteroids).

Pharmacodynamics and pharmacokinetics

Almagel is an antacid. Antacids neutralize the hydrochloric acid found in gastric juice, making them effective for treating acid-related diseases. Another component of the drug, aluminum hydroxide, also neutralizes the acid. In addition, the product contains magnesium hydroxide, which not only reduces the acidity of the stomach, but also eliminates the ability of aluminum hydroxide to cause constipation. Benzocaine has an analgesic effect, so the drug effectively copes with pain.

Almagel reduces the secretion of pepsin and reduces the activity of gastric juice, converting aluminum chloride into alkaline aluminum salts. The drug acts without the formation of carbon dioxide bubbles, so it does not cause flatulence. In addition, sorbitol has a laxative effect and enhances the separation of bile. By stimulating the synthesis of prostaglandins, the remedy protects the gastric mucosa. Exposure to magnesium hydroxide and aluminum hydroxide reduces the likelihood of inflammatory, erosive-hemorrhagic lesions from the use of irritating drugs.

Aluminum salts are absorbed into the intestine in a small amount, and magnesium ions - by 10%, but their concentration in the blood remains practically unchanged. The drug also contains benzocaine, which has almost no effect on the body, because it is absorbed in a minimal amount. The effect of Almagel for pain in the stomach occurs after 5 minutes, and its duration depends on the rate of gastric emptying. Yes, when using medicinal product on an empty stomach, the action lasts up to 60 minutes, and after application an hour after the last meal - up to 3 hours.

Instructions for use and regimen

Almagel

The drug is taken orally. Before each dose, the suspension must be thoroughly homogenized by shaking the vial.

Treatment

The drug is taken 45-60 minutes after meals and in the evening before bedtime.

Adults and children over 15 years of age are prescribed 5-10 ml (1-2 measuring spoons) 3-4 times a day. If necessary, a single dose can be increased to 15 ml (3 measuring spoons). Children aged 10 to 15 years are prescribed at a dose equal to half the adult dose.

After achieving a therapeutic effect, the daily dose is reduced to 5 ml (1 scoop) 3-4 times a day for 15-20 days.

Prevention

5-15 ml 15 minutes before taking drugs with an irritating effect.

Almagel A

inside. As prescribed by a doctor, 1-3 dosing (tea) spoons, depending on the severity of the case, 3-4 times a day half an hour before meals and in the evening before bedtime.

In children, the drug is used strictly according to the doctor's prescription: children under 10 years old are prescribed 1/3 dose for adults, and children from 10 to 15 years old - 1/2 dose for adults.

In diseases accompanied by nausea, vomiting and abdominal pain, treatment begins with Almagel A, and after the disappearance of these symptoms, they switch to Almagel.

The vial should be shaken before taking.

Almagel Neo

adults

Inside, 2 scoops of suspension with orange flavor 4 times a day 1 hour after meals and in the evening before bedtime. If necessary, a single dose can be increased to 4 scoops, but the maximum daily dose should not exceed 12 scoops.

Children over 10 years old

The dosage is determined by the attending physician - usually 1/2 dose for adults.

The course of treatment is no more than 4 weeks. Before taking the suspension must be homogenized by shaking the vial. It is advisable to take Almagel Neo undiluted. It is not recommended to take liquid within half an hour after taking the drug.

Side effects

Green Almagel and yellow Almagel A in isolated cases, they lead to the development of nausea, vomiting, stomach cramps, changes in taste, epigastric pain and constipation. These side effects are quickly eliminated by simply reducing the dose of the drug. When used in high doses, the suspension may cause drowsiness as a side effect.

Long-term use may reduce the concentration of phosphorus in the blood, leading to bone destruction (osteomalacia). In patients with kidney failure Almagel can provoke swelling of the extremities, dementia (dementia) and an increase in the concentration of magnesium in the blood.

Almagel Neo when taken in medium doses, it can cause allergies, nausea, vomiting, constipation or diarrhea. Use in high doses can lead to the development of the following side effects:

• a decrease in the concentration of phosphorus and calcium in the blood, resulting in bone destruction, osteoporosis and a tendency to fracture;
• increase in the concentration of magnesium and aluminum in the blood;
• increased concentration of calcium in the urine;
• deposition of calcium salts in the tubules of the kidneys (nephrocalcinosis);
• violation of the normal functioning of the kidneys;
• encephalopathy.

People suffering from renal insufficiency, in addition to the above symptoms, may experience thirst, a decrease in pressure and a decrease in reflexes as side effects of Almagel Neo.

Tablets Almagel T capable of provoking the development of side effects only when used in high dosages. To side effect tablets include thirst, discoloration of feces and constipation.

Overdose

In the case of a single use of an increased dosage of Almagel A, no other symptoms were noted, except metallic taste in oral cavity, flatulence and constipation.

With prolonged systemic use of the drug in high doses, the following symptoms may occur:

• bradycardia;
• neuromuscular paralysis;
• nausea and vomiting;
• changes in ECG parameters;
• anuria;
• the formation of kidney stones;
• drowsiness;
• numbness and pain in the muscles;
• severe intestinal obstruction;
• fatigue;
• respiratory depression;
• decrease in reflex function;
• hypoventilation;
• kidney failure;
• coma;
• heart failure.

In extremely severe cases of intoxication, there may be:

• hospitalization;
• intake of sorbents;
• gastric lavage;
• artificial stimulation of the gag reflex;
• symptomatic treatment.

Contraindications

All variants of Almagel have both general contraindications for use, and their own individual, characteristic of a particular form of the drug. Contraindications to the use of each form of Almagel are shown in the table:

In addition, Almagel A (yellow), due to the presence of benzocaine, cannot be taken simultaneously with sulfanilamide preparations (Biseptol, etc.).

Almagel Neo has relative contraindications, in the presence of which it should be used with caution and under close monitoring of the patient's condition. These relative contraindications are:

• breastfeeding period;
• liver pathology;
• alcoholism;
• traumatic brain injury;
• pathology of the brain;
• epilepsy;
• age under 10 years;
• teenagers aged 10 - 18 years.

Almagel or Phosphalugel?

On sale in pharmacies you can find another analogue of Almagel - Phosphalugel. Let's consider what is better Almagel or Phosphalugel?

Many people confuse these medicines, as they are very similar in composition. That is why it is very difficult to say which of the antacids is better. However, it should be noted that Phosphalugel has more properties. This allows you to assign it to various areas(not only as a symptomatic drug for diseases of the gastrointestinal tract). It can act as an absorbent and enveloping substance.

Unlike Almagel, Phosphalugl does not disrupt the metabolism of phosphates and calcium. This property allows a longer drug intake. In addition, Phosphalugel can be prescribed to pregnant women, children infancy and elderly patients. However, to say that some drug is better is definitely impossible. The treatment of each patient is selected individually by the doctor.

Almagel or Maalox?

Both Almagel and Maalox are a liquid dosage form - a suspension. In addition, the composition of both drugs is almost identical. Both of them contain as the main active ingredient aluminum and magnesium hydroxide. Therefore, you can choose any drug that a person likes more for some reason of a subjective nature.

However, if the pathology of the gastrointestinal tract is accompanied by a strong and pronounced pain syndrome, then it is better to prefer Almagel A suspension, which has the best anesthetic effect. In the presence of severe gas formation and bloating, the most preferred option is Almagel Neo, which contains a substance that eliminates this particular painful symptom. If there is no pronounced pain syndrome or gas formation, then you can choose any drug, depending on personal preferences.

special instructions

Long-term therapy must necessarily be accompanied by a meal rich in phosphorus. The manufacturer does not recommend taking more than 16 dosage spoons per day. If necessary, treatment with such high doses, the course should last no more than 14 days.

The drug is able to block the absorption of most drugs, which negatively affects their effectiveness. The recommended time interval between taking Almagel A and other drugs is 1-2 hours.

drug interaction

Medicines, the effectiveness of which decreases when taken together with Almagel A:

1. Isoniazid;
2. digitalis glycosides;
3. Tetracycline and all tetracycline antibiotics;
4. iron salts;
5. antihistamines;
6. beta blockers;
7. Phenothiazines;
8. Ciprofloxacin;
9. Ketoconazole.

Analogues

Structural analogues for the active substance:

• Agiflux;
• Almol;
• Alumag;
• Almagel A;
• Almagel Neo;
• Anacid forte;
• gastracid;
• Maalox;
• Maalox mini;
• Rivolox.

Analogues for pharmacological group(antacids):

• Additive calcium;
• Aktal;
• Alfogel;
• Alugastrin;
• Anacid forte;
• Antarite;
• Becarbon;
• Gastal;
• Gasterin;
• gastric;
• Gastroromazole;
• Gaviscon;
• Gaviscon forte;
• Gelusil;
• Gelusil varnish;
• Gelusil;
• Gestid;
• Daigin;
• calcium carbonate;
• Magalfil 800;
• Magnatol;
• Magnistad;
• magnesium oxide;
• Milk of magnesium;
• sodium bicarbonate;
• sodium bicarbonate;
• Relzer;
• Rennie;
• RioFast;
• Rokzhel;
• Rutacid;
• Simalgel VM;
• Scoralite;
• Talcid;
• Tams;
• Tannacomp;
• Tisacid;
• Topalkan;
• Phosphalugel;
• Andrews antacid.

How much does Almagel cost

Almagel is sold in pharmacies at various prices. It must be remembered that fluctuations in the cost of the same form of the drug depend not only on the pricing policy of the pharmacy chain, but also on the manufacturer. The fact is that Almagel is produced by various pharmaceutical concerns, for example, SOPHARMA, ACTAVIS and BALKANPHARMA-TROYAN AD. The cheapest will be Almagel produced by the Bulgarian corporation BALKANPHARMA-TROYAN AD. However, the quality of suspensions from all manufacturers is approximately the same, there are no strong differences. Therefore, when choosing Almagel, it is better to buy a drug from the manufacturer that is least counterfeited. Since these data may differ from each other depending on the region, it is best to consult a pharmacist who has information on this issue.

The cost of various dosage forms Almagel for ease of comparison and selection is reflected in the table:

Storage conditions

The shelf life of Almagel is 5 years. It should be stored in a well-closed container in a cool (from 5 to 150C - the optimal storage temperature) and protected from light.

Almagel A (aluminum hydroxide + magnesium hydroxide + benzocaine) is an antacid drug "enhanced" by the addition of an anesthetic. The drug neutralizes free hydrochloric acid in the stomach, which reduces the digestive capacity of gastric juice. The so-called "acid rebound" - the development of secondary gastric hypersecretion - the drug does not cause. It has a local anesthetic, enveloping and adsorbing effect, neutralizes the influence of aggressive factors on the mucous membrane of the gastrointestinal tract. The drug begins to act after 3-5 minutes from the moment of administration and provides a persistent and pronounced therapeutic effect for 70 minutes. During all this time, Almagel A provides a stable neutralization of the constantly produced gastric juice and reduces the concentration of hydrochloric acid in it to the required limits. Aluminum hydroxide (algedrate) inhibits the release of pepsin, neutralizes hydrochloric acid with the formation of aluminum chloride, which, in turn, entering the intestine and swallowing the alkaline "spirit of freedom" there, turns into an alkaline salt. Magnesium hydroxide also neutralizes hydrochloric acid, forming magnesium chloride. The antagonistic attitude of magnesium hydroxide in relation to the tendency of aluminum hydroxide to cause constipation ensures the smooth functioning of the physiological "conveyor" of the digestive tract. The third in turn, but not in importance component of Almagel A - benzocaine - has a long and pronounced local anesthetic effect. Sorbitol included in the preparation as an auxiliary substance facilitates bile excretion and exhibits a mild laxative effect, harmoniously complementing the action of magnesium hydroxide. Almagel A smoothly but surely shifts the pH to the “alkaline” side, “anchoring” it within the physiological limits from 3.5 to 4.5. The drug forms a protective shell, ensuring uniform distribution on the gastric mucosa active substances, and has a long local effect without the formation of carbon dioxide in the stomach, which, in turn, causes flatulence, discomfort in the epigastric region and secondary hypersecretion of hydrochloric acid.

Almagel neo is practically non-toxic and does not have teratogenic and mutagenic effects. In isolated cases in newborns whose mothers long time took the drug, there was an increase in tendon reflexes. In addition, in newborns there is a risk of a pathological increase in the amount of magnesium in the blood plasma, especially in a state of dehydration, and therefore long-term use of the drug for pregnant women and newborns is not recommended.

Almagel A is practically not absorbed in the gastrointestinal tract. The drug does not violate the water-salt balance and does not create any prerequisites for the appearance of alkalosis and other metabolic disorders. Almagel A does not irritate the urogenital tract and does not contribute to the formation of stones even with a long course of medication. Available as a suspension for oral administration. A measuring spoon is included in the package with the drug to ensure dosing accuracy. A single dose for adults is 1-3 scoops (their number is determined by the severity of the clinical case). Multiplicity of reception - 3-4 times a day 30 minutes before meals and at bedtime. The maximum daily dose is 16 tablespoons. In children, the drug is used exclusively on prescription and under medical supervision: children under 10 years old take a third of the "adult" dose, children from 10 to 15 years old - half. In diseases that are clinically manifested by nausea, vomiting and abdominal pain, pharmacotherapy begins with Almagel A, then the patient is transferred to Almagel. The bottle must be shaken before use. It is not recommended to take any other medicines 1-2 hours before taking Almagel A and after the same time after it.

Pharmacology

The instruction was approved by the Pharmacological Committee of the Ministry of Health of Russia on 03/02/2001.

Almagel A neutralizes free hydrochloric acid in the stomach, which leads to a decrease in the digestive activity of gastric juice. Does not cause secondary hypersecretion of gastric juice. It has a local anesthetic, adsorbing and enveloping effect, reduces the effect of damaging factors on the mucous membrane.

The therapeutic effect after taking the drug occurs after 3-5 minutes and lasts an average of 70 minutes.

Almagel A provides long-term local neutralization of continuously separated gastric juice and reduces the content of hydrochloric acid in it to the optimal limits for treatment. Aluminum hydroxide inhibits the secretion of pepsin, neutralizes hydrochloric acid, forming aluminum chloride, which in the alkaline environment of the intestine turns into alkaline aluminum salts. Magnesium hydroxide also neutralizes hydrochloric acid, turning into magnesium chloride. Thus, the effect of aluminum hydroxide, which causes constipation, is counteracted. Magnesium hydroxide and magnesium chloride are resorbed to a small extent and practically do not affect the concentration of magnesium ions in the blood.

Benzocaine has an effective and long-lasting local analgesic effect in severe pain syndrome.

Sorbitol, which is part of the preparation, promotes increased secretion of bile and exhibits a slight laxative effect, complementing the action of magnesium hydroxide.

Almagel A does not sharply increase the pH of the contents of the stomach, buffering its value from 4.0–4.5 to 3.5–3.8 (physiological value) between doses. The drug forms a protective layer, ensuring uniform distribution on the gastric mucosa active substances and provides long-term local action without the subsequent formation of carbon dioxide in the stomach, which, in turn, is the cause of flatulence, a feeling of heaviness in the epigastric region and a secondary increase in the secretion of hydrochloric acid.

According to the classification of Hodge and Sterner, the drug for oral administration refers to slightly toxic agents and does not have embryotoxic, teratogenic and mutagenic effects. In some cases, increased tendon reflexes were noted in newborns whose mothers took the drug for a long time. In addition, in newborns there is a risk of developing hypermagnesemia, especially in a state of dehydration, therefore, prolonged use of the drug by pregnant women and newborns is not recommended.

Pharmacokinetics

Release form

Suspension for oral administration white or almost white color, with a characteristic smell of lemon; during storage, a layer of clear liquid may form on the surface, with vigorous shaking of the vial, the homogeneity of the suspension is restored.

Excipients: sorbitol - 801.15 mg, gietellose - 15.26 mg, methyl parahydroxybenzoate - 10.9 mg, propyl parahydroxybenzoate - 1.363 mg, butyl parahydroxybenzoate - 1.363 mg, sodium saccharinate dihydrate - 0.818 mg, lemon oil - 1.635 mg, purified ethanol 96% - 98.1 mg, water - up to 5 ml.

170 ml - bottles (1) complete with dosing spoon - packs of cardboard.

Dosage

inside. As prescribed by the doctor, 1-3 dosing (tea) spoons, depending on the severity of the case, 3-4 times / day half an hour before meals and in the evening before bedtime.

In diseases accompanied by nausea, vomiting and abdominal pain, treatment begins with Almagel A, and after the disappearance of these symptoms, they switch to Almagel.

The vial should be shaken before taking.

Interaction

With the simultaneous use of Almagel A, it can reduce the therapeutic effect of tetracycline antibiotics, histamine H 2 receptor blockers, digitalis glycosides, iron salts, ciprofloxacin, phenothiazines, isoniazid, beta-blockers, indomethacin and ketokenazole, etc.

Side effects

In some cases, when taking the drug, there may be a change in taste sensations, nausea, vomiting, stomach cramps, pain in the epigastric region and constipation, which disappear after a dose reduction. At high doses, it may cause drowsiness.
Long-term treatment with the use of high doses of the drug and food poor in phosphorus can lead in predisposed patients to the development of phosphorus deficiency in the body, increased resorption and excretion of calcium in the urine and the occurrence of osteomalacia. Therefore, with prolonged use of the drug, it is necessary to ensure sufficient intake of phosphorus with food.
In patients with chronic renal failure, in addition to osteomalacia, edema of the extremities, dementia and hypermagnesemia can be observed.

Indications

• peptic ulcer of the stomach and duodenum in the acute phase;
• acute gastritis and chronic gastritis with increased and normal secretory function in the acute phase;
• duodenitis;
• enteritis;
• hiatal hernia;
• reflux esophagitis;
• functional bowel disorders, colitis;
• discomfort and pain in the epigastrium with errors in the diet, after drinking coffee, nicotine, alcohol;
• prophylactically in the treatment of corticosteroids and NSAIDs.

In the complex of therapeutic measures, Almagel A is prescribed to patients with diabetes.

Contraindications

• hypersensitivity to the components of the drug;
• severe impairment of kidney function;
• Alzheimer's disease;
• early childhood(up to 1 month).

Do not administer simultaneously with sulfonamides due to the presence of benzocaine in the preparation.

Application features

Use during pregnancy and lactation

Avoid prescribing to nursing mothers.

Application for violations of kidney function

Use in children

Contraindicated: early childhood (up to 1 month).

In children, the drug is used strictly according to the doctor's prescription: children under 10 years old are prescribed 1/3 dose for adults, and children from 10 to 15 years old - 1/2 dose for adults.

special instructions

The interval between taking Almagel A and other medicines should be 1-2 hours.

With prolonged use of the drug, it is necessary to ensure sufficient intake of phosphorus with food.