Otrivin nasal instructions for use. Spray in the nose for children Otrivin: instructions for use and analogues

Pharmacological properties

The therapeutic effect of Otrivin is provided by the active ingredient xylometazoline, which belongs to the group of vasoconstrictor drugs.

Reduces the amount of secreted mucus in the nasopharynx, facilitates its discharge, relieves swelling and irritation of the mucous membranes of the nose.

Indications

  • Symptomatic treatment of nasal congestion in colds, hay fever, other allergic rhinitis, sinusitis.
  • To facilitate the outflow of secretions in diseases paranasal sinuses nose.
  • Auxiliary therapy for otitis media (to eliminate mucosal edema).
  • To facilitate rhinoscopy.

Release form

Nasal spray, dosed 0.1%, 10 ml in a polymer spray bottle; 1 bottle in a cardboard box.

Dosage and administration

Nasal spray 0.1% is prescribed for adults and children over 12 years old, 1 injection in each nasal passage no more than 3 times a day.

The duration of treatment should not exceed 7-10 days.

The spray must be applied as follows:

  1. thoroughly clean the nose before using the drug;
  2. hold the bottle vertically, supporting the bottom with your thumb and placing the tip between two fingers;
  3. slightly tilt the bottle and insert the tip into the nostril;
  4. to carry out injection and at the same time a light breath through the nose;
  5. after use, before capping the tip, clean and dry the tip;
  6. in order to prevent infection, each vial with the drug can only be used by one person.

Children

Spray with an active ingredient concentration of 0.1% is used for adults and children over 12 years of age.

Use during pregnancy or lactation

The drug is not used during pregnancy and breastfeeding.

Application Features

Prolonged use can lead to degenerative processes in the nasal mucosa.

Contraindications

  • Hypersensitivity to xylometazoline or to any other component of the drug;
  • angle-closure glaucoma;
  • transsphenoidal hypophysectomy and surgical interventions with exposure of the meninges in history;
  • dry rhinitis (rhinitis sicca) or atrophic rhinitis.

Side effects

Allergic reactions, headache, blurred vision, increased blood pressure, arrhythmia, burning at the site of application.

Interaction with other medicinal products and other forms of interaction

Joint use with antidepressants and other sympathomimetic drugs should be avoided.

Contraindicated for use in patients receiving MAO inhibitors or who have taken them within the previous 14 days.

Use with caution in patients prone to nosebleeds.

With prolonged use, there is a risk of developing drug-induced rhinitis.

The ability to influence the reaction rate when driving vehicles or operating other mechanisms

The effect on the reaction rate is insignificant, but care should be taken when using the drug and managing potentially dangerous mechanisms.

Overdose

Violation of the heart rate, increased blood pressure, headache. Supportive care is prescribed to relieve symptoms.

It is considered one of the safest medicines for nasal congestion. Children's Otrivin is specially produced for babies from the first day of life. It is sold without a prescription, but it is advisable to use the medicine as prescribed by the pediatrician.

The active substance of Otrivin is Xylometazoline, it has a vasoconstrictive effect. It is this effect that is necessary in order to remove, which creates a feeling, as well as reduce the secretion of mucus. In children's Otrivin, the dosage of Xylometazoline is less than in an adult, because high doses are not required for a child.

Another feature of children's Otrivin is the content of sea water. By chemical properties it is close to the mucous membrane of the human nose, so the drug does not cause irritation and dryness. On the contrary, it moisturizes the nose, and it becomes easier for the little patient to breathe.

The tool is available in several dosage forms - spray, drops and solution for washing the nose. The spray has earned particular popularity because of the ease of administration - the product is evenly distributed over the nasal cavity, and one press on the sprayer is enough to administer.

The dosage of the active substance in children's Otrivin (spray) is 0.05%, the bottle is equipped with a special dispenser that allows you to inject the drug into the nasal cavity.

The drug exerts its action exclusively in the nasal cavity, is not absorbed into the blood, and does not cause systemic side effects.

Indications for Otrivin's use

The drug is used for the symptomatic treatment of nasal congestion.

The drug is used to relieve nasal congestion with the following diseases:

  • and .
  • allergic rhinitis.
  • Sinusitis.
  • Diseases of the deeper parts of the respiratory tract.

Otrivin is also used to reduce the formation of mucus in preparation for rhinoscopy - an examination of the nasal cavity. Children's Otrivin is intended for small patients from the first days of life.

You can use the medicine for preventive purposes - washing the nose during the cold season. This is especially true for younger students and children attending Kindergarten. Otrivin cannot completely protect the baby from infection, but it can reduce its likelihood.

Daily nasal hygiene can also be done with this drug, but others are usually used. dosage forms- drops and solution for washing.

Flushing is necessary to prevent mucus buildup and hard crusts that make it difficult for the baby to breathe. The spray can be applied to a cotton swab and used to clean the nasal passages.

Dosage and rules of use

It is recommended to purchase two products at the same time - Otrivin for children, containing Xylometazoline, and Otrivin Sea based on sea water. Spray Otrivin Sea does not contain any additional substances, except for sea water, and is necessary for preliminary cleaning of the nasal cavity from rough crusts. It is recommended to use it before using Otrivin Children spray.

Before using the spray, you need to blow your nose thoroughly, clean the nasal cavity with Otrivin More or rinse it with another agent, blow your nose thoroughly again. After that, Otrivin spray is injected into the nose using a dispenser.

Application rules:

  • Dosage for patients under 6 years old - one or two injections in each nostril 1/3 times a day. The duration of the course of treatment is not more than 10 days.
  • Children over 6 years old are recommended 2-3 spray injections 3 times a day in each nasal passage.

For adolescents over 12 years of age, an "adult" spray with a dosage of 0.1% is intended.It is advisable to carry out the injection procedure at least half an hour after going outside and at least an hour after returning. The temperature difference can cause hypothermia of the mucosa and provoke a longer course of the disease.

Possible contraindications to treatment

The tool is prohibited for children suffering from atrophic rhinitis - a disease in which degradation and thinning of the nasal mucosa occurs. It is manifested by a feeling of dryness in the nose, an increase and then a decrease in sensitivity to odors,.

In addition, individual hypersensitivity to the components of the drug is possible, and with its manifestations - nasal congestion, itching, pain, skin rashes- Otrivin should be replaced with a spray with a different active ingredient. The most hypoallergenic in this regard can be recognized as Otrivin More spray, which does not cause hypersensitivity reactions.

Children should not use medicine intended for adults.

Also, the medicine should be used with caution in infants - at this age, any treatment should be prescribed by a doctor.This drug should also be avoided in children with congenital heart defects, diabetes, pathologies thyroid gland, glaucoma. Children who have undergone surgery on the membranes of the brain and pituitary gland should not use Otrivin.

Side effects and overdose

Prolonged use may cause discomfort in the nose - burning, dryness, irritation when inhaling hot or cold air, frequent sneezing, swelling of the mucous membrane.

Prolonged or improper use of the remedy leads to the opposite effect - instead of facilitating breathing, it causes a constant.

Other effects that are observed with prolonged use of the drug:

  • Headaches, nausea and vomiting.
  • Visual disturbances - blurred, tired eyes.
  • Violations heart rate, feeling heartbeat.
  • Depressive disorders, insomnia.

It is also possible to increase blood pressure, impaired vascular tone and other pathologies associated with cardiovascular system. If the drug is used incorrectly, an overdose of the drug is possible.

It is manifested by a sharp increase in blood pressure, headache, significant visual impairment, tinnitus, and in severe cases, confusion. Treatment of overdose with Otrivin is symptomatic.

Interaction with other drugs

The agent cannot be combined with other vasoconstrictors for the nasal cavity, regardless of their active substance. In addition, the combination with drugs that affect vascular tone is undesirable - this can lead to an unpredictable reaction.

The combination with antidepressants and monoamine oxidase inhibitors (a class of psychotropic drugs) is highly undesirable.

One of the side effects of Otrivin is depressive state therefore, with simultaneous treatment with antidepressants, their effectiveness may decrease.

Such drugs are rarely used in children, much more often they are prescribed to adults, so children can be used with little or no significant restrictions.

The best analogues of Otrivin for children

Toddlers are often worried about colds, which are accompanied by rhinitis or nasal congestion. There are a number of drugs that modern pharmacology offers, aimed at eliminating this ailment. Consider what Otrivin is for children, as well as instructions for its use.

Otrivin for children is vasoconstrictor drops which is aimed at relieving nasal congestion. Produced in the form of a nasal spray and drops. Active ingredient this medicine- xylometazoline hydrochloride.

It also contains the following additional ingredients:

  • sodium dihydrophosphate dihydrate;
  • sodium hydrogen phosphate dodecahydrate;
  • benzalkonium chloride;
  • sorbitol;
  • hypromellose;
  • sodium chloride;
  • purified water.

In appearance, this drug is a clear liquid with a subtle odor.

You can buy Otrivin for children in every pharmacy without a prescription. Its average price varies within 150 rubles. or 60 UAH.

Otrivin is prescribed for the treatment of children in such situations:

  • elimination of signs of rhinitis in ARVI and other respiratory pathologies;
  • in the treatment of otitis;
  • preparation for surgical intervention in diseases of the upper respiratory tract;
  • for more active removal of mucus with sinusitis.

Is Otrivin addictive? This drug is not suitable for long-term use as it may indeed be habit-forming.


Instructions for use

How to use Otrivin? To alleviate the condition of the baby, the following manipulations should be carried out:

  • Rinse nasal cavity the child with the help of an aspirator and ask him to blow his nose;
  • put the baby on one side, drip 1-2 drops into the nose, wait a couple of minutes, and then do the same manipulation on the other side.

Drops act instantly, nasal congestion disappears almost immediately. The duration of action of Otrivin is about 10 hours. After this time, if necessary, drip the nose again.

The duration of such treatment should be no more than 5 days. This time is enough to cure a runny nose in a baby.

Otrivin Baby

Given pharmacy remedy used for infants and children up to a year. This is a specialized complex, which includes not only drops, but also an aspirator for cleansing the nose. Otrivin Baby is prescribed not only for the treatment of colds, but also to alleviate the condition of allergic rhinitis.

How to use Otrivin Baby? Step-by-step instruction:

  1. First of all, you need to drip the baby's nose saline solution into each nostril. This helps to thin the mucus for more comfortable removal.
  2. After treating the nose with a solution, it is required to remove the accumulated mucus using an aspirator with a disposable tip. To do this, plant the child or leave it in a reclining position if it is a baby. Insert the tip of the aspirator into the nostril, the mother should bring the other end to her lips. Carefully, slowly suck out the mucus. It is easy to control its amount, since the aspirator tube is transparent. Manipulation should be done from the second nostril.
  3. After the accumulated mucus is completely removed, nothing will prevent the child from breathing comfortably.

This procedure for the baby should be carried out no more than 2 times a day.


This medicinal preparation applies to older children - not younger than 6 years. The main indications for the use of Otrivin with menthol are:

  • removal of redness and swelling;
  • elimination pain and congestion;
  • accumulation of fluid in the hearing aid;
  • moisturizing the ear walls;
  • excessive dryness in the mucous membranes;
  • improvement of blood circulation in the inflamed part.

Many pediatricians prescribe Otrivin menthol drops for the symptomatic treatment of a hearing aid. The medicine should be used in this way:

  • remove wax from ears cotton swab;
  • hold the vial in hot water to warm the medicine;
  • put the baby on its side;
  • pull back the ear a little for faster penetration;
  • drip into the ear, according to the dosage prescribed by the attending physician;
  • repeat the manipulation with the second ear.

On average, the dosage for children is 1-2 drops no more than 2 times a day.


Contraindications for use

These nasal drops for children have a number of contraindications that should be considered before using them. The drug should not be used in such cases:

  • atrophic rhinitis;
  • persistent high blood pressure;
  • violation of the heart rhythm;
  • dysfunction of the thyroid gland;
  • transferred operations on the brain;
  • glaucoma.

But these signs are observed in children in extremely rare cases, so Otrivin is suitable for the treatment of almost every child.

When using this medicinal product In rare cases, the following side effects may occur:

  • swelling, rashes or itching in the form of an allergy;
  • headache;
  • sleep disturbance;
  • increased blood pressure;
  • burning and tingling;
  • nausea with vomiting.

It's important to know! When side effects you need to stop using Otrivin, and then immediately contact your doctor!


Analogues

Let's spend comparative characteristic the most common analogues and Otrivin.

Which is better: Otrivin or Nazivin

Both of these drugs belong to the group of vasoconstrictors. They relieve swelling in the mucous membrane of the nasal cavity, and also eliminate inflammation. The difference between Otrivin and Nazivin is only in the form of release of these drugs. The tool in question is presented in a greater number and variety of forms. Nizivin is available only in the form of drops for children. Also different and active substance. Nazivin active ingredient is oxymetazoline hydrochloride. But, despite this, they have an identical effect on the children's body.


Which is better: Otrivin or Vibrocil

Vibrocil also belongs to a number of vasoconstrictor drugs. It contains 2 active ingredients: phenylephrine and dimethindene maleate. That is, Vibrocil has both a vasoconstrictor and anti-allergic effect at the same time. If we compare these drugs, then their effectiveness depends on the severity of rhinitis. Otrivin has an immediate effect, which allows you to quickly alleviate the condition with severe rhinitis. But it has more side effects than Vibrocil. Therefore, many experts consider Vibrocil the safest drug for treating children. The drops in question are used in cases where the child needs to immediately alleviate the condition.

In spite of a large number of benefits of Otrivin, its use in the treatment of a child must be agreed with the attending physician. But keep in mind that it can be addictive. Therefore, the drug is not suitable for long-term treatment.

solution (nosal drops) 0.05%: fl. 10 ml with cap-drip.
Reg. No: 6625/04/09/14 dated 09/29/2014 - Canceled

Excipients: sodium dihydrogen phosphate dihydrate, sodium hydrogen phosphate dodecahydrate, sodium chloride, disodium edetate, benzalkonium chloride, methylhydroxypropylcellulose 4000mPa x S, sorbitol 70%, purified water.

10 ml - plastic bottles (1) with a dropper cap - packs of cardboard.

Description of the medicinal product OTRIVIN ® drops 0.05% created in 2011 on the basis of instructions posted on the official website of the Ministry of Health of the Republic of Belarus. Date of update: 05/22/2012


pharmachologic effect

Xylometazoline belongs to the group of local vasoconstrictors (decongestants) with α-adrenomimetic action:

  • causes constriction of the blood vessels of the nasal mucosa, thus eliminating swelling and hyperemia of the nasal mucosa and nasopharynx. Facilitates nasal breathing with rhinitis.

Otrivin ® is well tolerated by patients even with sensitive mucous membranes. Otrivin ® has a balanced pH characteristic of the nasal cavity. The composition of the drug includes moisturizing ingredients - sorbitol and methylhydroxypropylcellulose, which can reduce the symptoms of irritation and dryness of the nasal mucosa that occur with prolonged use of xylometazoline.

In therapeutic concentrations, it does not irritate the mucous membrane, does not cause hyperemia. The action occurs within a few minutes and lasts for 12 hours.

Pharmacokinetics

At topical application practically not absorbed, plasma concentrations are so low that they cannot be determined by modern analytical methods.

Dosing regimen

intranasally

For infants and children under 6 years of age- 1-2 drops in each nasal passage 1-2 times / day; should not be used more than 3 times / day.

For children over 6 years old: 2-3 drops in each nasal passage 3-4 times / day.

Before using the drug in infants and children under the age of 6 years, you should consult a specialist.

Before use, clean the nasal passages.

Side effects

With frequent and / or prolonged use - irritation and / or dryness of the mucous membrane of the nasopharynx, burning, tingling, sneezing, hypersecretion.

Rarely - swelling of the nasal mucosa, palpitations, tachycardia, arrhythmias, increased blood pressure, headache, vomiting, insomnia, visual impairment; depression (with prolonged use of high doses).

Use in children

Children under 6 years of age should use the drug under adult supervision. Before using the drug in infants and children under the age of 6 years, you should consult a specialist.

special instructions

Do not use continuously for more than 10 days:

  • prolonged or excessive use may cause increased secretion of mucus and swelling of the mucous membrane.

It should be used with caution in patients with hypersensitivity to sympathomimetics, which is manifested by symptoms such as insomnia, dizziness, tremor, cardiac arrhythmia and high blood pressure.

Rarely, in young children, anxiety and insomnia may occur when using the drug, in which case you should consult a specialist.

Children under 6 years of age should use the drug under adult supervision.

Impact on ability to drive vehicle or equipment

Xylometazoline, in dosages exceeding those recommended, may affect the ability to drive a vehicle or operate machinery.


Preparation: OTRIVIN ®

Active ingredient: xylometazoline
ATX code: R01AA07
KFG: Vasoconstrictor drug for local use in ENT practice
ICD-10 codes (indications): H66, H68, J00, J01, J30.1, J30.3, Z51.4
KFU code: 24.05.01
Reg. number: P No. 011649/05
Date of registration: 11.09.08
The owner of the reg. acc.: NOVARTIS CONSUMER HEALTH S.A. (Switzerland)

PHARMACEUTICAL FORM, COMPOSITION AND PACKAGING

? Dosed nasal spray (with menthol and eucalyptus) 0.1% in the form of a white opalescent liquid with the smell of menthol and eucalyptus.

Excipients: sodium dihydrophosphate dihydrate, sodium hydrogen phosphate dodecahydrate, sodium chloride, benzalkonium chloride (in the form of a 50% solution), sorbitol 70%, disodium edetate, levomenthol (menthol), cineol (eucalyptol), macrogol glyceryl hydroxystearate, purified water.

10 ml - polyethylene bottles with a dosing device (1) complete with a tip and a protective cap - packs of cardboard.

INSTRUCTION FOR THE SPECIALIST.
The description of OTRIVIN spray is approved by the manufacturer.

PHARMACHOLOGIC EFFECT

Vasoconstrictor drug for local use in ENT practice. Xylometazoline has an alpha-adrenergic action. It causes narrowing of the blood vessels of the nasal mucosa, thus eliminating swelling and hyperemia of the nasopharyngeal mucosa. Facilitates nasal breathing in rhinitis.

The drug is well tolerated by patients with sensitive mucous membranes, its effect does not interfere with the separation of mucus. The drug has a balanced pH characteristic of the nasal cavity.

In therapeutic concentrations, it does not irritate the mucous membrane, does not cause hyperemia.

The action occurs within a few minutes after application and lasts for 12 hours.

PHARMACOKINETICS

When applied topically, it is practically not absorbed, plasma concentrations are so small that they cannot be determined by modern analytical methods.

INDICATIONS

Acute respiratory diseases with the phenomena of rhinitis;

Acute allergic rhinitis;

Pollinosis;

Sinusitis;

Eustachitis;

Otitis media (to reduce swelling of the mucous membrane of the nasopharynx);

Preparation of the patient for diagnostic manipulations in the nasal passages.

DOSING MODE

Adults and children over 6 years old- 1 injection in each nasal passage (if necessary, can be used repeatedly), usually 3-4 injections per day are sufficient.

Duration of application - no more than 10 days in a row.

SIDE EFFECT

Local reactions: with frequent and / or prolonged use - irritation and / or dryness of the mucous membrane of the nasopharynx, burning, tingling, sneezing, hypersecretion; rarely - swelling of the nasal mucosa.

System reactions: with frequent and / or prolonged use - nausea; rarely - tachycardia, palpitations, arrhythmia, increased blood pressure, headache, dizziness, vomiting, insomnia, blurred vision, allergic reactions, with prolonged use of the drug in high doses - depression.

CONTRAINDICATIONS

Arterial hypertension;

Tachycardia;

Severe atherosclerosis;

Glaucoma;

atrophic rhinitis;

Hyperthyroidism;

Surgical interventions on the meninges (in history);

Children's age up to 6 years;

Hypersensitivity to the components of the drug.

FROM caution used in patients with diabetes mellitus, cardiovascular diseases, hypersensitivity to adrenergic drugs, accompanied by symptoms of insomnia, dizziness, cardiac arrhythmia, tremor, high blood pressure.

PREGNANCY AND LACTATION

During pregnancy and lactation, the drug should be used only after a thorough assessment of the risk-benefit ratio for the mother and fetus, it is not allowed to exceed the recommended doses.

SPECIAL INSTRUCTIONS

Influence on the ability to drive vehicles and control mechanisms

Xylometazoline does not affect the ability to drive vehicles and control mechanisms.

OVERDOSE

Symptoms: increased side effects (increased blood pressure, increased heart rate, sometimes confusion).

Treatment: conducting symptomatic therapy.

DRUG INTERACTIONS

Incompatible with MAO inhibitors and tricyclic antidepressants.

TERMS AND CONDITIONS OF DISCOUNT FROM PHARMACIES

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of the reach of children at a temperature not exceeding 25°C. Shelf life - 2.5 years.