Ventolin for children instructions for use. Dosage form Ventolin easy breathing: syrup

R.03.A.C Selective beta-2-agonists

R.03.A.C.02 Salbutamol

The active substance of this drug is salbutamol sulfate . In addition, it contains tetrafluoroethane - 1 dose.

Release form

In pharmacies you can find Ventolin spray can (Ventolin inhaler). In addition, Ventolin in nebules is sold as solution for inhalation . The medicine can also be found in tablets and in the form syrup .

pharmachologic effect

Bronchodilator means.

Pharmacodynamics and pharmacokinetics

The drug is used to prevent bronchospasms . it bronchodilator , or rather, selective beta-2-agonist . It increases lung capacity and mucociliary clearance , activates the work ciliated epithelium , improves mucus secretion, expands coronary arteries , reduces the content of potassium, acts as hyperglycemic and lipolytic agent , has an effect on glycogenolysis and the release of insulin, increases the risk of occurrence.

The medicine acts quite quickly, almost 5 minutes after application (maximum - after 30-90 minutes). The duration of the effect is about 5 hours.

10-20% of salbutamol after application are in the lower respiratory tract. They are absorbed into the lung tissue and blood, but do not break down. Remaining quantity active substance lingers in the inhaler or in the oropharynx, after which it is swallowed and actively broken down when passing through the liver with transformation into phenolic sulfate .

The degree of connection with plasma proteins is approximately 10%.

Entered into the blood, salbutamol is cleaved within 72 hours in the liver and is excreted mainly in the urine as phenolic sulfate or in an unchanged state. A small part is excreted in the feces.

Indications for use

An inhaler and a solution for it with Ventolin are used for chronic form, and COPD with reversible airway obstruction.

Contraindications

The drug should not be used in chronic heart failure , hypersensitivity to components, childhood up to 18 months, .

Side effects

As a rule, among the side effects noted fingers, the appearance of anxiety. In addition, the following adverse reactions are possible:

• hypersensitivity in the form hypotension , bronchospasm , collapse ;
• hyperactivity;
• paradoxical bronchospasm ;
• muscle cramps;
• hypokalemia ;
• lactic acidosis ;
• strong heartbeat;
• expansion of peripheral vessels;
• extrasystole ;
• supraventricular ;
• irritation of the mucous membrane of the mouth and pharynx.

Application instruction of Ventolin (Way and dosage)

Instructions for the use of Ventolin warns that the medicine must be used correctly, regardless of the form of release, otherwise the treatment process may go wrong.

In addition, the drug must be taken only after consulting a doctor.

The instruction on Ventolin for inhalation in the form of an aerosol informs that for the use of the drug it is necessary to use nebulizer with a mask and endotracheal tube .

Ventolin Nebula, which is sold as an inhaler solution, is used without dilution. The duration of inhalation is about 10 minutes. The drug can be diluted with a sterile solution of sodium chloride (0.9%). It must be used in well-ventilated rooms, as some of the drug enters the environment.

The instructions for Ventolin Nebula for inhalation recommend a dose of 2.5 mg. If necessary, it can be increased to a maximum of 5 mg. Frequency of use - 3-4 times a day. For adult patients, if necessary, in a hospital, the dosage is increased to 40 mg per day.

Aerosol for inhalation is designed for approximately 200 times of use. It can be used by adult patients and children from 2 years of age after appointment by a specialist. For the purpose of long-term maintenance therapy, adults are usually prescribed 200 mcg up to 4 times a day. To prevent bronchospasms in childhood, 100-200 mcg (1-2 inhalations) is used.

The syrup is prescribed to patients in adulthood, 2 ml 3-4 times a day. If necessary, the dosage can be increased to 4 ml.

Overdose

When using the drug in doses above the norm, it is possible hypokalemia , tachycardia nausea, decreased blood pressure, muscle tremor , vomiting, arousal, respiratory alkalosis , headache , hyperglycemia , hypoxemia . In rare cases, they appear tachyarrhythmia , peripheral vasodilation, convulsions, ventricular flutter .

Used for treatment cardioselective beta-blockers , but with caution if history have seizures bronchospasm .

Interaction

Ventolin for inhalation is not recommended for use in conjunction with non-selective beta-adrenergic blockers . In patients with this drug also increases the effect of stimulants of the nervous system and tachycardia .

If you combine an aerosol and a solution for inhalation with xanthines , increases the likelihood of tachyarrhythmias . FROM Levodopoy and means for inhalation increases the risk of developing severe ventricular arrhythmias . Together with anticholinergic medicines can increase intraocular pressure. When assigned with diuretics and GKS rises hypokalemic action .

Terms of sale

The drug is sold by prescription only.

Storage conditions

Keep the medicine out of the reach of children and well protected from light. It can not be frozen or heated, the optimum temperature is not higher than 30 ° C.

Best before date

The drug should be stored no longer than 2 years.

Analogues

Analogues of Ventolin, as well as Ventolin Nebula and Ventolin Easy Breathing in pharmacies can be obtained, as a rule, the following:

• fan ;
• Nebutamol ;
• Salamol Steri-Neb ;
• Salamol-Eco ;
• Salamol-Eco Easy Breath ;
• Salbutamol-Intel ;
• Salbutamol-Neo .

All of them have different prices. In many cases, analogues cost less than Ventolin itself.

children

Inhalations for children can be used for cupping seizures bronchospasm at a dosage of 100-200 mcg (1-2 inhalations). Maintenance therapy with Ventolin - up to 200 mcg 4 times a day (2 inhalations). For prevention, 100-200 mcg is used 10-50 minutes before the provoking factor (1-2 inhalations).

For children, spacers "Babyhaler" or "Volumatic" are used.

Clinical Efficiency this tool in children under 18 months when used nebulizer has not been researched.

Ventolin is a bronchodilator drug. It is widely used in the treatment of bronchial asthma at its various stages. As you know, the most powerful bronchodilator is adrenaline, which was used for choking attacks inspired by bronchial asthma until the middle of the 20th century. However, the side effects of this biologically active substance secreted by the adrenal cortex - palpitations, hypertension, agitation - excluded the possibility of its further use as a means of stopping asthma attacks. This is due to the fact that adrenaline interacts both with beta-1-adrenergic receptors, located mainly in the heart, and with beta-2-adrenergic receptors of the bronchi. For this reason, selective beta-2-adrenergic receptors were created, which marked a new era in the treatment of bronchial asthma. The first such drug was salbutamol, which appeared on the world pharmaceutical market in the late 60s of the last century. Ventolin is the original salbutamol from GlaxoSmithKline. Today, Ventolin is the "gold standard" for the relief of asthma attacks. The drug has a strong bronchodilatory effect, preventing or completely eliminating bronchospasm and reducing resistance in the respiratory tract. It does not have a negative effect on the heart and blood vessels (provided that it is used in the dosages indicated in the instructions for use). Increases the lumen of the coronary vessels. Raises the level of glucose in the blood, has a fat-burning effect.

The drug begins to act within 5 minutes after inhalation and reaches a peak of activity after 0.5-1.5 hours. Duration of action - 4-6 hours. The lower respiratory tract reaches only 10-20% of the administered dose. The main losses occur in the inhaler itself, in which part of the dose remains, and the other part settles in the oral cavity and pharynx, after which it is swallowed. Ventolin is contraindicated in individuals with individual intolerance to salbutamol, as well as at the risk of preterm birth. AT pediatric practice the drug is used from the age of two. Inhalations should not be performed more than 4 times a day. If the need for the use of the drug increases, this indicates a worsening of the clinical situation. The rules for operating the inhaler and checking its performance are detailed in the instructions for use. For unstable or severe bronchial asthma, Ventolin should not be the main component of treatment. If the patient notes a weakening of the effect of the drug (determined by the need to use it more often and / or in larger quantities), then he should consult a doctor. Ventolin should be used with caution in individuals with signs of thyroid intoxication. The inhaler must be cleaned in accordance with the instructions for use at least once every 7 days. Joint reception Ventolin with non-selective beta-blockers is not desirable.

Pharmacology

Selective agonist of β 2 -adrenergic receptors. In therapeutic doses, it acts on β 2 -adrenergic receptors of bronchial smooth muscles and has a short-term (4 to 6 hours) bronchodilatory effect on β 2 -adrenergic receptors with a rapid onset of action (within 5 minutes) with reversible airway obstruction.

It has a pronounced bronchodilating effect, preventing or stopping bronchospasm, reduces resistance in the airways. Increases VC. Increases mucociliary clearance (in chronic bronchitis up to 36%), stimulates mucus secretion, activates the functions of the ciliated epithelium.

In the recommended therapeutic doses, it does not adversely affect the cardiovascular system, does not cause an increase in blood pressure. To a lesser extent, compared to medicines of this group, has a positive chrono - and inotropic effect. Causes expansion of the coronary arteries.

It has a number of metabolic effects: it reduces the concentration of potassium in plasma, affects glycogenolysis and insulin release, has a hyperglycemic (especially in patients with bronchial asthma) and lipolytic effect, increases the risk of acidosis.

Pharmacokinetics

absorption and metabolism

After inhalation, 10-20% of the dose of salbutamol reaches the lower respiratory tract. The rest of the dose remains in the inhaler or is deposited in the oropharynx and then swallowed. The fraction deposited in the respiratory tract is absorbed into the lung tissues and blood, but is not metabolized in the lungs.

Distribution

The binding of salbutamol to plasma proteins is 10%.

Metabolism

When released into the systemic circulation, salbutamol undergoes hepatic metabolism and is excreted mainly by the kidneys in unchanged form or in the form of phenolic sulfate. The swallowed part of the inhalation dose is absorbed from the gastrointestinal tract and undergoes significant first-pass metabolism through the liver, turning into phenolic sulfate. Unchanged salbutamol and the conjugate are excreted primarily by the kidneys.

breeding

Introduced in/in salbutamol has a T 1/2 4-6 hours. Excreted partly by the kidneys and partly as a result of metabolism to inactive 4 "-O-sulfate (phenolic sulfate), which is also excreted mainly by the kidneys Only a small part of the administered dose of salbutamol is excreted through the intestine. Most of the dose of salbutamol administered to the body intravenously, orally or inhaled by, excreted excreted within 72 hours.

Release form

Aerosol for inhalation dosed in the form of a white or almost white suspension.

Excipients: propellant GR106642X (1,1,1,2-tetrafluoroethane, HFA 134a, norflurane); does not contain chlorofluorocarbons.

200 doses - aluminum inhalers (1) with a plastic dosing device with a protective cap - packs of cardboard.

Dosage

The drug Ventolin is intended only for inhalation administration by inhalation through the mouth.

An increased need for the use of beta2-adrenergic agonists may be a sign of exacerbation of asthma. In such a situation, it may be necessary to re-evaluate the patient's treatment regimen with consideration of the advisability of prescribing simultaneous therapy with corticosteroids.

Since an overdose may be accompanied by the development of adverse reactions, the dose or frequency of use of the drug can be increased only on the recommendation of a doctor.

The duration of action of salbutamol in most patients is 4 to 6 hours.

A spacer may be used in patients who have difficulty synchronizing inspiration with a pressurized metered dose inhaler.

In children and infants receiving Ventolin, it is advisable to use a pediatric spacer device with a face mask.

For the relief of an attack of bronchospasm in adults, the recommended dose is 100 or 200 mcg; children - 100 mcg, if necessary, the dose can be increased to 200 mcg. It is not recommended to use the Ventolin inhaler more than 4 times / day. The need for such frequent use of additional doses of Ventolin or sharp increase dose indicates a worsening of asthma.

To prevent attacks of bronchospasm associated with exposure to an allergen or caused by physical activity, adults - 200 mcg 10-15 minutes before exposure to a provoking factor or exercise; children - 100 mcg 10-15 minutes before exposure to a provoking factor or load, if necessary, the dose can be increased to 200 mcg.

With long-term maintenance therapy for adults - up to 200 mcg 4 times / day; children - up to 200 mcg 4 times / day.

Rules for the use of an inhaler

Checking the inhaler

Before using the inhaler for the first time or if the inhaler has not been used for a week or more, you should remove the cap from the mouthpiece by slightly squeezing the cap from the sides, shake the inhaler well and spray twice into the air in order to make sure the inhaler is working properly.

Using an inhaler

1. Remove the cap from the mouthpiece by slightly squeezing the cap from the sides.

2. Inspect the mouthpiece inside and out to make sure it is clean.

3. Shake the inhaler well.

4. Hold the inhaler between the index and thumb in a vertical position with the bottom up, while the thumb should be located on the base under the mouthpiece.

5. Take a slow deep exhalation, clasp the mouthpiece with your lips, without squeezing it with your teeth.

6. While inhaling as deeply as possible through the mouth, simultaneously press the top of the inhaler to release one inhaled dose of salbutamol.

7. Hold your breath for a few seconds, remove the mouthpiece from your mouth, then exhale slowly.

8. To receive the second dose, holding the inhaler in a vertical position, wait about 30 seconds and then repeat steps. 3-7.

9. Close the mouthpiece tightly with a protective cap.

Steps 5, 6, and 7 should not be rushed. You should start inhaling as slowly as possible, just before pressing the inhaler valve. The first few times it is recommended to practice in front of a mirror. If "fog" is visible coming out of the top of the inhaler or from the corners of the mouth, then you should start all over again from stage 2.

If the doctor has given other instructions for using the inhaler, then the patient must strictly follow them. If the patient has difficulty using the inhaler, he should consult a doctor.

Cleaning the inhaler

The inhaler must be cleaned at least once a week.

1. Remove the metal cartridge from the plastic case and remove the mouthpiece cover.

2. Thoroughly rinse the plastic body and mouthpiece cover under running warm water.

3. Dry the plastic body and the mouthpiece cover completely both outside and inside. Avoid overheating.

4. Place the metal cartridge in the plastic case and put on the mouthpiece cover.

Do not immerse the metal can in water.

Overdose

Symptoms: signs and symptoms of an overdose of salbutamol are transient phenomena, pharmacologically mediated by stimulation of beta-adrenergic receptors, such as a decrease in blood pressure, tachycardia, muscle tremor, nausea, vomiting. The use of large doses of salbutamol can cause metabolic changes, including hypokalemia, it is necessary to control the concentration of potassium in the blood serum. With the use of high doses, as well as with an overdose of short-acting beta-agonists, the development of lactic acidosis was observed, therefore, in case of an overdose, control over an increase in serum lactate and the possibility of developing metabolic acidosis may be indicated (especially if tachypnea persists or worsens, despite the elimination of other signs of bronchospasm, such as like wheezing).

Interaction

Salbutamol is not contraindicated in patients receiving MAO inhibitors.

In patients with thyrotoxicosis, Ventolin enhances the effect of CNS stimulants, tachycardia.

Theophylline and other xanthines, when used simultaneously with salbutamol, increase the likelihood of developing tachyarrhythmia.

Simultaneous appointment with anticholinergics (including inhalation) may increase intraocular pressure.

Diuretics and corticosteroids enhance the hypokalemic effect of salbutamol.

Side effects

The adverse reactions presented below are listed according to the damage to organs and organ systems and the frequency of occurrence. The frequency of occurrence is defined as follows: very often (> 1/10), often (> 1/100 and< 1/10), нечасто (>1/1 000 and< 1/100), редко (>1/10 000 and< 1/1 000), очень редко (< 1/10 000, включая отдельные случаи). Категории частоты были сформированы на основании клинических исследований препарата и пострегистрационного наблюдения.

From the immune system: very rarely - hypersensitivity reactions, including angioedema, urticaria, bronchospasm, decreased blood pressure and collapse.

On the part of metabolism and nutrition: rarely - hypokalemia. Therapy with beta 2 agonists can lead to clinically significant hypokalemia.

From the nervous system: often - tremor, headache; very rarely - hyperactivity.

From the side of the heart: often - tachycardia; infrequently - a feeling of palpitations; very rarely - arrhythmias (including atrial fibrillation, supraventricular tachycardia and extrasystole).

From the side of the vessels: rarely - peripheral vasodilation.

On the part of the respiratory system, chest organs and mediastinum: very rarely - paradoxical bronchospasm.

On the part of the gastrointestinal tract: infrequently - irritation of the mucous membrane of the oral cavity and pharynx.

On the part of the musculoskeletal and connective tissue: infrequently - muscle cramps.

Indications

Bronchial asthma:

• relief of symptoms of bronchial asthma when they occur;
• prevention of attacks of bronchospasm associated with exposure to an allergen or caused by physical activity;
• use as one of the components in long-term maintenance therapy of bronchial asthma.

Other chronic lung diseases associated with reversible airway obstruction, including chronic obstructive pulmonary disease (COPD), chronic bronchitis, emphysema.

Bronchodilators should not be the sole or main component of the treatment of unstable or severe bronchial asthma. In the absence of a response to salbutamol in patients with severe bronchial asthma, glucocorticosteroid therapy is recommended in order to achieve and maintain disease control. Failure to respond to salbutamol therapy may indicate a need for urgent medical advice or treatment.

Contraindications

• management of preterm birth;
• threatened abortion;
• hypersensitivity to the components of the drug.

Salbutamol should be used with caution in patients with thyrotoxicosis, tachyarrhythmia, myocarditis, heart defects, aortic stenosis, coronary heart disease, severe chronic heart failure, arterial hypertension, pheochromocytoma, decompensated diabetes mellitus, glaucoma.

Application features

Use during pregnancy and lactation

During pregnancy, the drug should be prescribed only if the expected benefit of therapy for the mother outweighs the potential risk to the fetus.

During post-registration surveillance, rare cases of various malformations in children, including the formation of a "cleft palate" and malformations of the limbs, were identified while taking salbutamol during pregnancy. In some of these cases, mothers took multiple concomitant medications during pregnancy. Due to the absence of a permanent nature of defects and the background incidence of congenital anomalies, which is from 2 to 3%, a causal relationship with the drug has not been established.

Salbutamol is likely to pass into breast milk and is therefore not recommended for use in breastfeeding women unless the expected benefit to the mother outweighs the potential risk to the baby. There is no data on whether salbutamol present in breast milk has a harmful effect on the newborn.

Fertility

There are no data on the effect of salbutamol on human fertility. In preclinical studies, no adverse effects on animal fertility have been identified.

Application for violations of liver function

Application for violations of kidney function

Use in children

May be used in children if indicated.

special instructions

Bronchodilators should not be the sole or main component of the treatment of unstable or severe bronchial asthma.

An increased need for the use of short-acting bronchodilators, in particular beta2-adrenergic agonists, to alleviate the symptoms of bronchial asthma indicates a worsening of the course of the disease. In such cases, the patient's treatment plan should be reviewed. Sudden and progressive worsening of bronchial asthma may pose a potential threat to the life of the patient, therefore, in such situations, the advisability of prescribing or increasing the dose of glucocorticosteroids should be considered. In patients at risk, daily monitoring of peak expiratory flow is recommended.

Therapy with beta 2-adrenergic agonists, especially when administered parenterally or by nebulizer, can lead to hypokalemia.

Particular caution is recommended in the treatment of severe attacks of bronchial asthma, since in these cases hypokalemia may increase as a result of the simultaneous use of xanthine derivatives, glucocorticosteroids, diuretics, and also due to hypoxia. In such situations, it is recommended to control the concentration of potassium in the blood serum.

As with the use of other means for inhalation therapy, when taking salbutamol, paradoxical bronchospasm may develop with increased wheezing immediately after the use of the drug. This condition requires immediate treatment using an alternative formulation of salbutamol or another short-acting inhaled bronchodilator. The drug Ventolin should be immediately discontinued, the patient's condition should be assessed and, if necessary, another fast-acting bronchodilator should be prescribed to continue treatment.

If there is no effect from the use of a previously effective dose of inhaled salbutamol for at least 3 hours, the patient should consult a doctor about the need to take any additional measures.

Patients should be instructed on the correct use of the Ventolin inhaler.

Influence on the ability to drive vehicles and control mechanisms

Content

Bronchial asthma is a dangerous pathology that requires constant monitoring from a person. To prevent bronchospasm, accompanied by suffocation, you must always carry a drug that has a bronchodilator effect. One of the best drugs in this group is Ventolin.

Composition and form of release

The pharmacological action of Ventolin is due to its composition. Active ingredient the drug affects beta-2 receptors, causing bronchial dilatation. The antiallergic property is explained by the reduction in the release of histamine from mast cells. The drug is produced in several dosage forms: a solution for inhalation in nebulizers, tablets, syrup and an aerosol can with a spray mouthpiece. The composition of Ventolin, which is indicated in the instructions:

Ventolin - a hormonal drug or not

Obstruction (narrowing) of the airways is dangerous disease, therefore, with its progression, therapy is often required hormonal means. Beta-2-agonist Ventolin does not belong to this group of drugs, therefore it is safe for health. Main active substance salbutamol acts directly on the receptors of the bronchial muscles, contributing to its relaxation.

Indications for use

The drug Ventolin is prescribed for various diseases of the respiratory system and their complications. According to the instructions, the indications for the use of the drug are as follows:

• relief of asthma attacks;
• Chronical bronchitis;
• prevention of bronchospasm, which is caused by excessive exercise or allergies;
• chronic obstructive disease lungs;
• application in the composition complex therapy in the maintenance treatment of asthma;
• emphysema.

Method of application and dosage

According to the instructions, beta-adrenergic receptor Ventolin is prescribed for adults and children from 2 years of age. According to the indications, the drug can be used for infants infancy, for pregnant women, during lactation, but if the benefits of treatment outweigh the health risks of these patient groups. Each form of the drug has its own dosage and method of application.

Ventolin aerosol

Used to inhale medication through the mouth. Assign Ventolin for inhalation to adult patients and the elderly in a daily dosage of not more than 800 mcg. To stop an attack, the drug is prescribed in a single dose of 100 to 200 mcg. To prevent bronchospasm, 2 inhalations (200 mcg) are recommended before the expected contact with the allergen or before physical activity. With long-term maintenance therapy, 100 to 200 mcg is prescribed up to 4 times a day. The duration of treatment with Ventolin is not determined by the instructions, but by the doctor individually.

Ventolin in nebules

Do not use Ventolin solution for nebulizer as a solution for injection or oral administration. The drug is intended for use by inhalation using an inhaler and face mask, endotracheal or T-tube. Intermittent pressure ventilation solution may be used (under medical supervision). The recommended dosage at home is 2.5-5 mg 4 times a day, in the hospital - up to 40 mg daily dose.

Tablets

According to the instructions Bronchodilator Ventolin in tablet form is prescribed for adults and children from 2 years of age. The average dosage for adults is 2-4 mg 3-4 times a day. If necessary, the dose can be increased to 8 mg 4 times a day (maximum 32 g). Long-acting tablets are prescribed 4-6 mg every 12 hours. The course of treatment is prescribed by the doctor individually in each case.

Syrup

Assign to adult patients and children from 2 years. A syrup of 150 mg is taken orally half an hour before meals. Dosage for adults - 4 ml 3 times a day. In case of urgent need, the amount of the drug can be increased to 8 ml, but not more than 3 times a day. A syrup of 50 ml is prescribed for adults, 2 ml 2 times a day.

special instructions

If the prescribed dosage of the drug does not bring relief, you should consult a doctor. An increased need for a drug indicates an exacerbation of the pathological process. In this case, the patient needs to adjust the treatment, since the deterioration of the condition poses a threat to his life. The drug is used with caution in thyrotoxicosis. In the treatment of attacks of bronchospasm, hypokalemia may increase, especially with the simultaneous use of glucocorticosteroids, diuretics, xanthine derivatives.

The appointment of the drug during pregnancy and breastfeeding is carried out in the most extreme cases. The medication should be used with caution, as sometimes hyperglycemia and / or tachycardia occurs in the mother and child. There were no special studies on the effect of the drug on the fetus, but doctors recorded deviations in the embryonic development of the baby in mothers who used this medicine while carrying a child. Officially, the connection of Ventolin with these pathologies has not been established.

In childhood

Due to the lack of information on the effectiveness of the drug in early childhood, Ventolin is not prescribed for babies under 1.5 years old. Children's dosages of different dosage forms:

• aerosol: relief of an attack - 100-200 mcg once, prevention of bronchospasm - 100 mcg in 15 minutes, maintenance therapy - 100-200 mcg up to 4 times a day;
• solution for inhalation: 2.5–5 mg no more than 4 times a day;
• tablets: up to 12 years - 1-2 mg, over 12 years - 2-4 mg 3-4 times a day;
• syrup: 2 ml 2-3 times a day.

drug interaction

The instructions indicate that it is not recommended to use the drug together with non-selective beta-blockers (proprapronol). It is also contraindicated in patients undergoing treatment with monoamine oxidase inhibitors (MAOIs). During the use of Ventolin in thyrotoxicosis, tachycardia may occur.

With simultaneous use with Theophylline and other xanthines, the likelihood of developing tachyarrhythmia increases. Joint use with anticholinergic substances contributes to an increase in intraocular pressure. Use with Levodopa and other means for inhalation anesthesia contributes to the occurrence of severe arrhythmias.

Side effects

When using Ventolin, you may experience adverse reactions organism from different systems and organs. Among them:

• immune system: lowering blood pressure, bronchospasm, urticaria, hypotension, collapse;
• metabolism: hypokalemia, glycogenolysis, lactic acidosis (lactic acidosis), insulin secretion decreases.
• nervous system: limb tremor, headache;
• heart: tachycardia, palpitations, arrhythmia, extrasystole;
• gastrointestinal tract: irritation of the mucous membrane of the pharynx, mouth;
• musculoskeletal system: convulsions.

Overdose

The best antidotes for an overdose of Ventolin are cardioselective β-blockers (Atenolol, Bisoprolol). Most common symptoms when the permissible dose is exceeded:

• low blood pressure;
• muscle cramps;
• ventricular flutter;
• excitation;
• hyperkalemia;
• respiratory alkalosis;
• hypoxemia;
• hallucinations;
• expansion of peripheral vessels.

Contraindications

According to the instructions for use, Ventolin has a number of contraindications. Do not prescribe the drug in the following conditions:

• threatened abortion;
• management of preterm birth;
• hypersensitivity to any of the components of the drug.

There are diseases in which the medicine should be used with caution. Relative contraindications include:

• diabetes;
• severe heart failure;
• ischemia;
• heart defects;
• thyrotoxicosis;
• myocarditis;
• tachyarrhythmia;
• arterial hypertension;
• glaucoma.

Terms of sale and storage

The drug is dispensed by prescription. Store at a temperature not exceeding 30 ° C, out of the reach of children and pets. Do not expose the medication to direct sunlight and freeze. The shelf life of the medicinal product is 2 years from the date of manufacture.

Analogues

If necessary, the doctor can replace Ventolin with a similar medication. Direct analogues of the drug are:

• Fan. Used to relieve asthma attacks, with chronic obstructive bronchitis and other diseases that occur with bronchospasm. According to the instructions - you can not drink alcohol while taking Ventilor.
• Nebutamol. Assign to inhibit hyperactivity of the bronchial tree, relieve spasm of smooth muscles of the bronchi, rapid sputum discharge. Do not use medication for patients with a high risk of developing allergic reactions.
• Salbutamol. The drug is prescribed for the relief and prevention of an attack of bronchial asthma. Do not use in epilepsy, insufficiency of liver and / or kidney function, during pregnancy.
• Salamol-Eco. Bronchodilator drug that stimulates beta 2-adrenergic receptors. When used, there is a risk of developing a low concentration of potassium in the blood.

Price

Did you find an error in the text?
Select it, press Ctrl + Enter and we'll fix it!

• R03 MEDICINES USED IN OBSTRUCTIVE RESPIRATORY DISEASES
  • R03A ADRENERGIC DRUGS FOR INHALATION USE
    • R03AC Selective beta-2-adrenergic agonists
      • R03AC02 Salbutamol

Indications for use

• bronchospastic syndrome,
• bronchial asthma (including nocturnal - prolonged forms) - prevention and relief,
• COPD (including chronic bronchitis, emphysema).

Contraindications

• Hypersensitivity to Ventolin,
• children's age (under 2 years old - for oral solution and syrup, under 4 years old - for inhalation powder and metered-dose aerosol without a spacer).
• management of preterm birth
• threatened abortion.

Use with caution

Salbutamol should be used with caution in patients with thyrotoxicosis, tachyarrhythmia, myocarditis, heart defects, aortic stenosis, coronary heart disease, severe chronic heart failure, arterial hypertension, pheochromocytoma, decompensated diabetes mellitus, glaucoma.
Ventolin tablets, syrup and aerosol are prescribed with extreme caution during lactation, because the safety of the drug for infants has not been studied enough.

Use during pregnancy and during breastfeeding

During pregnancy and lactation, according to the doctor's decision on the appropriateness of his appointment.

Dosage and administration

With bronchospasm, Ventolin is prescribed for inhalation for adult patients at a dose of 100-200 mcg per dose.
For prophylactic purposes, 200 mcg is prescribed three to four times a day.
If the patient is going to be exposed to an allergen or exercise stress, the recommended dosage of the drug is 200 mcg 15 minutes before the expected irritant effect.

To stop attacks of bronchospasm in children, the use of Ventolin should be in the following doses:
2-6 years - 1-2 mg;
6-12 years - 2 mg;
Over 12 years old - 2-4 mg.
Prophylactic doses involve the use of 100-200 mcg three times a day.

Ventolin for inhalation should not be used more than 4 times in 24 hours.
Elderly patients are advised to adhere to a dose of 2 mg, which should be taken three times a day.
Ventolin Nebula is used for inhalation, the dosages of which are as follows:
For adults: 2.5 mg up to 4 times a day, while the maximum allowable dose is 5 mg;
For children from one and a half years: maximum 2.5 mg up to 4 times a day.

In order to properly use Ventolin Nebula, you must follow these steps:
Remove the nebula from the package;
Shake a little and turn until opening, holding the top edge;
Insert the nebula into the nebulizer with the open side down and press lightly;
Assemble the design of the nebulizer;
Use for inhalation.
In general, the number of doses of this form of medication should not exceed 8-10 times.
If the treatment does not bring the expected results, it is necessary to review and adjust its scheme.
Spacers can be used to increase the effectiveness of the drug.

The drug in the form of a syrup is prescribed 2 ml 3-4 times a day for adult patients, while if necessary, you can increase the dose to 4 ml.

The drug in tablets is taken in such doses as:
Adult patients: 1-2 tablets three to four times a day (maximum 4 tablets per dose);
Elderly patients: 1 piece 3-4 times a day;
Children from 2 to 6 years old: 0.5-1 tablet with the same frequency of administration as in adults and the elderly;
Children from 6 to 12 years old: 1 tablet per dose, multiplicity - as for adults;
Children over 12 years old: the dosage and frequency of taking Ventolin is the same as in adults.

Side effect

Headache;
Slight tremor of the limbs (hands);
Vasodilation and increased heart rate;
Paradoxical bronchospasm;
Excitation and excessive increase in activity in children;
Violation of the heart rhythm;
Allergic symptoms: bronchospasm, angioedema, arterial hypotension.

Overdose

Tachycardia;
Decreased blood pressure;
Excitation;
Vomit;
tachyarrhythmia;
muscle tremor;
hallucinations;
convulsions;
In the blood: lactic acidosis, hypokalemia, leukocytosis, hypophosphatemia;
Respiratory alkalosis.
In case of overdose medicine carry out symptomatic treatment, prescribe drugs from the group of cardioselective beta-blockers.

Interaction with other drugs

Ventolin should not be combined with non-selective beta-blockers. It enhances the action of drugs that stimulate the central nervous system. It also increases the risk of developing arrhythmias against the background of the use of cardiac glycosides. The drug is not contraindicated in patients taking MAO inhibitors. The likelihood of tachyarrhythmias increases when taken with theophylline and other xanthines. The combination of the drug with drugs for inhalation pain relief and levodopa can provoke ventricular arrhythmias. Simultaneous use with anticholinergics may cause an increase in intraocular pressure. Such side effect Ventolin, as hypokalemia, may increase when taking diuretics and glucocorticosteroids.