Cough syrup Tussin and Tussin plus: instructions. Tussin and Tussin Plus: instructions for use Use during pregnancy and lactation

Tussin plus- combination drug, has antitussive, mucolytic and expectorant effect.
Guaifenesin is a mucolytic agent that stimulates the secretory cells of the bronchial mucosa that produce neutral polysaccharides, depolymerizes acid mucopolysaccharides, reduces viscosity and increases the volume of sputum, activates the ciliary apparatus of the bronchi, facilitates the removal of sputum and promotes the transition of an unproductive cough into a productive one.
Dextromethorphan is an antitussive that is similar in potency to codeine. It does not have a narcotic, analgesic and hypnotic effect, does not inhibit the respiratory center and the activity of the ciliated epithelium, suppresses cough of any origin.

Indications for use:
Indications for the use of the drug Tussin plus are: diseases respiratory tract with difficult discharge of viscous sputum: pharyngitis, sinusitis, influenza, acute tracheitis, bronchitis of various etiologies (including complicated by bronchiectasis), bronchial asthma, pulmonary tuberculosis, pneumonia, cystic fibrosis; sanitation of the bronchial tree in the pre- and postoperative periods.

Mode of application:
Syrup Tussin plus take orally, after meals, using a teaspoon or measuring cup.
For adults and children over 12 years old - 2 teaspoons every 4 hours.
For children 6-12 years old - 1 teaspoon every 4 hours.
The amount of the drug in a measuring cup up to the TSP mark corresponds to 1 teaspoon (5 ml).

Side effects:
Side effects when using syrup Tussin plus may occur from the gastrointestinal tract: rarely - nausea, vomiting, epigastric pain, diarrhea.
Other: drowsiness.

Contraindications:
Contraindications to the use of syrup Tussin plus are: moist cough with abundant sputum; hypersensitivity to the components of the drug.

Pregnancy:
Prescribed with caution Tussin plus during pregnancy and lactation ( breastfeeding).

Interaction with others medicines:
Can be used simultaneously Tussin plus with bronchodilators, antimicrobials, cardiac glycosides, antitussive drugs.
Codeine makes it difficult to pass loose sputum. The concurrent use of other

mucolytics.

Overdose:
Symptoms of drug overdose Tussin plus: Particularly high doses of guaifenesin may cause nausea and vomiting.
Treatment: measures should be taken to replenish body fluids, monitor the level of electrolytes.
Symptoms caused by dextromethorphan: agitation, dizziness, respiratory depression, impaired consciousness, decreased blood pressure, tachycardia, muscle hypertonicity, ataxia.
Treatment: gastric lavage, reception activated carbon, symptomatic therapy.

Storage conditions:
A drug Tussin plus should be stored in a dry, dark place at temperatures between 15° and 30°C. Storage in the refrigerator is not allowed.

Release form:
Syrup Tussin plus - orange-red color with a slight smell of cherry: in bottles of 118 ml, complete with a measuring cup, in a cardboard box.

Compound:
5 ml syrup Tussin plus contain guaifenesin 100 mg and dextromethorphan hydrobromide 10 mg;
excipients: citric acid, flavor, glycerol, high fructose corn syrup, sodium saccharin, sodium benzoate, cherry flavor, FD&C red #40, water.

Additionally:
Should not be taken Tussin plus for the treatment of persistent cough without a doctor's prescription.
During treatment, it is recommended to take a sufficient amount of liquid.
It is advisable to combine with postural drainage or chest vibration massage.
It is possible to stain the urine pink.
Urinary 5-hydroxyindoleacetic acid (using the nitrosonaphthol reagent) may be falsely elevated due to the effect of guaifenesin metabolites on color (guaifenesin should be discontinued 48 hours prior to urine collection for this test).
Guaifenesin and its metabolites can cause discoloration in the determination of vanillylmandelic acid in the urine and falsely increase the results of the test with it for catechins (Guaifenesin should be stopped 48 hours before urine collection for this test).
If, after 7 days of taking the drug, the cough persists or hyperthermia, skin rash, prolonged headache, sore throat are noted along with the cough, you should consult your doctor.
Caution should be exercised in children aged 2 to 12 years with persistent or chronic cough on the background of bronchial asthma or with increased sputum production (careful medical supervision is required before prescribing guaifenesin).
Do not administer to children under 2 years of age without the advice of a specialist.

The composition contains as auxiliary components: water, red dye No. 40, cherry flavor, sodium benzoate, sodium saccharin, corn syrup with a large amount of fructose, , flavor additive, citric acid.

Release form

Produced in the form of an orange-red syrup with a slight cherry smell in polyethylene terephthalate bottles of 118 milliliters. The set includes a measuring cup.

pharmachologic effect

Is mucolytic agent. Included in the drug dextromethorphan suppresses afferent impulses of increased intensity from the mucous membrane of the respiratory tract, increases the cough threshold, reducing the frequency of dry cough. Although this active ingredient is similar in strength to , it has no analgesic properties, does not inhibit the activity of the ciliated epithelium and the respiratory center.

Guaifenesin due to increased secretion of liquid components of bronchial mucus, increased activity of the ciliated epithelium and depolymerization of acid mucopolysaccharides, it has an expectorant effect.

The duration of the antitussive effect is up to six hours.

Pharmacodynamics and pharmacokinetics

The active components of the drug are rapidly absorbed from the gastrointestinal tract - half an hour after ingestion. They penetrate tissues that contain acidic mucopolysaccharides and are metabolized in the liver. Excreted with sputum with the help of the lungs or in the form of inactive with the help of the kidneys.

Action dextromethorphan begins to appear 15-25 minutes after ingestion and lasts up to six hours. This active ingredient is very rapidly metabolized in the liver and excreted mainly by the kidneys as unchanged dextromethorphan.

Indications for use

The syrup is indicated for diseases of the respiratory tract, accompanied by a cough with difficult expectoration of sputum of increased viscosity:

• acute, colds and ;
• bronchiectasis ;
• different;
• cystic fibrosis ;

Contraindications

The medicine should not be taken with:

• severe organic diseases of the central nervous system;
• children under six years of age;
• wet cough with a lot of sputum;
• in history;
• hypersensitivity to the contents of the syrup.

Do not take simultaneously with other medicines that contain similar active substances.

Side effects

As side effects, there may be:

• (hyperthermia , skin rash );
• hyperexcitability (often in children);
• or ;
• exacerbation ulcers duodenum and stomach ;
• (nausea and ).

Instructions for use (Method and dosage)

According to the instructions for Tussin Plus, the syrup must be taken orally after meals using a measuring cup or a teaspoon.

Overdose

Overdose observed nausea and vomiting, ataxia, muscle hypertonicity, decreased consciousness, impaired consciousness, respiratory depression, and excitation . Treatment consists of gastric lavage, and symptomatic therapy.

Tussin+(trip)

Somehow, everything turned out spontaneously ... In general, Vika and I bought 2 bottles of tussin, went to my house, changed clothes, bought cigarettes, grapefruit juice and went to the roof of one building.
Having knocked over 2 jars of tussin, washed down with juice, we began to wait - to wait for the Coming. Under the Tussin, time moves in an extremely incomprehensible way, but I dare to assume that we sat there for an hour and a half or two. I lay, looked at the sky, Vika sang songs, it was very atmospheric, light rain dripped.
Deciding that there was no effect, we decided to go home. I thought that we would walk for an hour and go home to sleep, but no such luck. Of the sensations at that time, I had only a slight relaxation and trembling in my legs, as it was when I fell down the stairs, stoned with a scan :)
Vika had nothing at all, as she said, she was angry and waited. We went home. We walk along Trostenetskaya street, no residential buildings, only the road, the Kommunarka plant, the inscription "TIRE SERVICE" in the manner of "HOLLYWOOD", gg. Vika said "Let's lie down on the grass", I agreed. And I did not see anything unusual in this, as if every day at night I was lying on the grass by the road. We lay down and everything went off with her: each lamp she had was a separate large, bright sun, and these rays extending from it reached the sky and fell on her. I thought that she was kidding and that in fact there was nothing like that, we got up and she suffered.
You know, if you look at a bright light for a long time, and then close your eyes, then this silhouette from the light bulb remains ... Vika began to look at the lanterns, then look at the sky and see a variety of things. I did not believe her, but my condition changed, I was already much happier. She told me to try it too. Of course, I didn’t believe it, I looked at this lantern, looked at the sky and ... and indeed ... I had some kind of bar code in front of me, which then turned into 4 headlights from a jeep driving in the dark, then they turned into some kind of fucking squirrel)) but later I realized that it was a beaver.
We went further. Even then, time passed sooooo slowly. 2 such fuckers are walking around the city at night and looking at every street lamp that comes across. We reached the bridge, Vika saw a very bright light bulb and decided to sit down and look at it, some man walked by and then Vika yelled that she saw a horse and caught it .. Oh, yes, another important thing - Vika constantly told me, that she didn't fit in and that without tussin she would have thought the same way. Well, I believed it ... I thought that yes, indeed ... in real life she could be the same ...
We got to May Day and decided to lie down on the grass again, lay down and it was so gorgeous... some kind of warm earth, the smell of mowed grass, and as Vika said, it was very comfortable for her to lie down. She had never been so comfortable in her life. I thought about it and also felt it: all the muscles were relaxed, nothing interfered anywhere, it didn’t prick, everything was soft and comfortable. I don’t know how long we lay there, but soon we decided to go further on business :) Then I got up. And I realized that I was fucked up. We went out onto the track and even then, if I'm not mistaken, we laughed from everything in a row. that I yawn, my lower jaw is taken away, a dull smile appears on my face, I cover my mouth with my hand and after the words "fuckaaaaat" I start to laugh.
Moreover, it could happen at any moment ... it was like a cough. We moved up the hill, to the Oktyabrskaya. Even then we walked with a drunken gait ... and I felt, at least, drunk. We walked and cried, walked and cried. We got to the prospect, went to the courtyard of the building, where all sorts of Stoves, Benches, etc. shop to go to the toilet. I showed Vika where to go there, she left me, I also decided to go to the toilet. Standing at some thing, unzipping my fly, taking out my penis and exposing the head of the penis, I decided to try to pee. And damn, I just stood there until Vika came!!! I thought about something like that .. and it seemed to me that I stood like that for only three seconds, but it turns out more, much more :)
We came to the Soyuz-Onin, sat on a bench, there were a bunch of people on our right and on the left, I took out cigarettes, took 2 pieces and put them on the bench. We smoked ... smoked and laughed. The people who were on our left left, there was one girl and 2 boys. And one kid in a plaid shirt looked at us and also neighed like a drug addict, Mr. We also decided to go for a walk further, went down to the avenue, one man asked us for a cigarette. Imagine, he comes up to me with huge bolts, asks for a lighter, then Vika jumps up with no smaller pupils and says "This one is better !!" and gives him a lighter and laughs :) He left, we went on, I looked back and then for the first time I realized how slowly everything was dragging on. We walked as much as I usually walk in half a minute. But it seemed to me that we had been walking for half an hour, at least. Somehow we reached the alley on Felix where we sat down and also decided to sit. They sat down, neighing from everything. Then Vika fell silent and said, “Damn, Tyoma, it just dawned on me that I thought that everything that happened to me I could do without Tussin. How could I even think of this?!?” and then such a rzhach began for both of them, which is just fucked up. Then it seemed to me that Vika had one less pigtail and told her that she had fucked her pigtail, she was scared. In fact, the pigtail just hid. We sat like this, sat ... we remembered that we forgot our cigarettes at the Soyuz-online, but it was too lazy to go ...
I didn't want anything: I didn't want to eat, I didn't want to drink, I didn't want to smoke... I was just fine. Such an apathetic state :) And Vika saw a man in glasses, printed on paper, hanging on the window of the Svyaznoy store. As she said later, she was really scared of him. She thought it was a man looking at us from the balcony. We still decided to go for cigarettes, went closer to this man, Vika looked at him, cursed and we went. Yes, by the way, a good Russian mate began to shove out of her :) Through the word, literally. And I had a corral that she generally disgusted me. And not because of the fact that she swears. And I generally stopped liking her outwardly, ggg. Shaw is just awful. But it was just a run.
So, we are going for cigarettes, Vika all the posters began to seem super-real. And the same Nescafe .. and this cup of coffee, she smells it ... And then she wanted to eat. In general, we didn’t go for cigarettes, but we went to the toilet again in the same yard. This time both went :) We decided to go home already. Vika began to show how sober and sane she is. Well, I thought that maybe everything is really good and you can go home. But only then did we notice each other's pupils, and this trembled us. Mom was supposed to leave at 5 in the morning, the clock was somewhere around 4.30. then they realized that we had just messed up and started laughing. Went to the park to sit on a bench. Decide
or wait an hour until my mother is sure to leave. Sat down, I turned on the player and we listen to music, trying to sleep. And then the fucking thought comes to me that my mother is not at home. Well, she’s not here, I was sure that she had left earlier. Came home and it really was like that :) gg
We sat down in the kitchen to drink tea. All I have left is some shabby Chinese tea that leaves a sweet aftertaste when drunk. Vika wanted to eat, I gave her bread and sausages. She takes a bite of the bread and says that he is just a dick, she bites the sausage and says that she is just a dick too. I did not understand then what it meant, I thought that she liked them. But as she explained later, she bit off the bread and realized that there was more than enough taste, there was too much of it and it filled everything. All her receptors began to work hard. She washed it all down with tea and started yelling that it was too minty .. and that it literally burns. Although, in fact, there was no mint. We went to sleep, lay down. When Vika closed her eyes, all sorts of letters and generally strange things appeared. I had some barcodes again, then I had some kind of one inscription in the middle in front of my eyes and the font changed every second. From what Vika had, I remember a glass, a disc hangs on a spit above it and spins. And it has flowers on it. She also had a skeleton of a fish, on the ribs of which a little man was rubbing, which was a lot, like in a kaleidoscope :) We somehow fell asleep. woke up at 12 something.

Mom had already arrived and, having examined each other's eyes, we decided that Vika needed to go to Lisa, and I needed to see her off :) I bought cigarettes, we sat down near the church on Independence Square. We recalled yesterday and at some point I noticed that Vika was looking at my eyes, I look at her eyes and pupils and they became normal .. and I say "Your eyes ...". some kind of childish, sincere joy filled us, that Vika even jumped and squealed:) we sat with her, chatted and realized that our pupils had become small. Too small :) But nothing, small ones are better than big ones. I put her on a trolley bus and went home, where my pupils dilated again, then Vika called and said that she had the same thing :)

Conclusion: you can try in life :) The first time I didn’t like it at all, but this time everything was gorgeous. The main thing is a good company. It's good that we were on the street and not at home. Usually people, having accepted something, turn on music or watch a movie, and half of the action goes to stupidity. We chatted and laughed at each other over ourselves. Time passed incredibly slowly. Vika asked, "Do you remember when we just started drinking tussin on the roof? It seems to me that a year has passed."
Although, about this, Vika and I were also stupid: time goes slowly or quickly. It was difficult to understand then, but now it is impossible to describe at all :)

"Tussin plus" is a drug for the treatment of cough, which has a complex effect. It consists of two active component. The tool is used as a method of therapy for respiratory pathologies caused by inflammation or an infectious process. The medication is prescribed to eliminate dry cough.

General characteristics and composition of the drug

Today, Tussin Plus is considered one of the most popular drugs for combating respiratory ailments. This medicinal product is manufactured by Health Life. The composition of the drug includes two active components:

1. Guaifenesin.
2. Dextromethorphan hydrobromide.

In addition, in the manufacture of the drug, additional ingredients are used, such as:

• glycerol;
• corn syrup;
• lemon acid;
• cherry flavoring;
• menthol;
• sodium saccharin;
• water.

Syrup "Tussin plus" is available in bottles of 118 milliliters.

The medicine has an orange-red tint and a faint cherry aroma. The product has a sweet taste. Many patients claim that this property makes it convenient to use.

Features of the drug

The syrup suppresses coughing fits and promotes the removal of sputum from the respiratory system. The components that make up this medication make the mucus more liquid. Due to this, it is easily removed from the bronchi. Together with sputum, bacteria and viruses are released from the body, which provoke the disease. The person's condition is improving. Thus, the drug is recommended by experts to eliminate attacks of dry cough in patients with infectious and viral pathologies of the respiratory system.

For childhood diseases (for example, whooping cough), Tussin Plus syrup is also prescribed. The composition of the drug includes substances that do not have analgesic or hypnotic properties. They do not have a depressing effect on the respiratory center. The components that are used in the manufacture of the product do not provoke drug dependence and addiction. Additional ingredients (corn syrup, glycerin) help to moisturize and soften the pharyngeal mucosa, reduce the feeling of discomfort and tissue irritation. The medicine works for about 3-4 hours. The drug is rapidly absorbed from the gastrointestinal tract. It is metabolized in the liver and excreted in the sputum. Inactive drug metabolites are excreted by the kidneys.

In what cases is the remedy prescribed?

In the presence of respiratory pathologies that are infectious, viral or inflammatory in nature and are accompanied by a dry cough without sputum, Tussin Plus is recommended. Instructions for use indicates that this medicine is used for therapy with the following pathologies:

• acute form laryngitis or pharyngitis;
• inflammatory processes in sinus sinuses, trachea;
• tuberculosis;
• bronchial asthma;

• flu
• cystic fibrosis;
• inflammatory processes in the lungs or bronchi.

Contraindications to the use of the drug

The drug should not be used in the presence of the following conditions:

1. The patient is under two years of age.
2. Severe pathologies of the central nervous system.
3. Ulcers of the digestive organs.
4. Postponed bleeding of the gastrointestinal tract.
5. Wet cough with discharge a large number sputum.

The drug is not prescribed in the presence of hypersensitivity to the ingredients that make up its composition.

Additional Information

It is not recommended to use "Tussin Plus" at the same time as preparations containing the same components that are part of this medication. The use of the drug at any time of gestation is contraindicated.

This is due to the fact that the active ingredients that are used in the production of syrup have a negative impact on the health of the expectant mother and child. If necessary, the use of the drug during lactation, the process of breastfeeding should be stopped.

How to use the medicine correctly?

If the specialist does not prescribe a specific dosage of the medication to the patient, it must be measured using a measuring cup, which is in the package with the Tussin Plus preparation.

The instructions for use indicate that such a mixture is recommended to be consumed three times a day. Children from two to six years old are given half a teaspoon of the remedy. The medication is drawn up to the mark of 0.5 ml on a measuring cup. For patients aged 6 to 13, a higher dose of medication is recommended. It is equal to one teaspoon of syrup. The medication is taken every 4 hours. Persons from twelve years of age and older are prescribed medicine in the amount of two measuring cups. The duration of therapy with this drug is three to four days. However, if necessary, the course of its administration is increased. This decision must be made by a specialist depending on the condition of a particular patient.

Side effects while taking the medication

Most patients tolerate this drug quite well. However, some patients show signs allergic reaction. They are associated with hypersensitivity to the components that make up the drug. In this case, patients experience the following symptoms:

• feeling of nausea and bouts of vomiting;
• dizziness;

• itching skin;
• rashes, the appearance of urticaria;
• decrease in blood pressure.

If a patient develops these symptoms, the doctor decides whether to stop the course of therapy and replace the drug.

Medicines with a similar effect

In the event of the appearance of signs of individual intolerance, the specialist selects means that are safe for the patient and give a similar effect. The medicine "Tussin plus" has the following analogues:

1. "Padeviks".
2. "Codeterp".
3. "Glycodin".
4. "Thedein".
5. "Kodarin".
6. "Codepsin".

One of the main selection criteria medicinal product patients is its financial availability. How much does Tussin Plus cost? Average price for this remedy in Russian Federation is approximately 180 rubles.

Opinion of buyers about the effectiveness of the drug

You can find a lot of reviews about Tussin Plus. It should be emphasized that most of them indicate positive properties this medicine. Patients claim that the remedy is quite effective and safe to use (subject to strict adherence to the instructions). Some people claim that the drug helps to cope with a cough even in cases where other medicines do not give a tangible result. The syrup, according to consumers, turned out to be more effective than analogues that have a higher price. It is often used as a treatment for infections. respiratory system in persons childhood.

In young patients, against the background of the use of the drug, improvement quickly occurs. Coughing attacks disappear, mucus leaves the bronchi. The infection process stops and the child recovers.

However, not all patients believe that the medication is effective. Some people have used it for several days without seeing any noticeable improvement. There are patients who were dissatisfied with the taste of the syrup. Not everyone likes the composition of the medicine either. Others consider it insufficiently natural and safe for the body. The unnatural shade of the syrup also raises doubts among consumers. They believe that this color is due to the presence of additional artificial additives (dyes), which adversely affect human health. In addition, the tool can not be used to treat small patients under the age of two.

Conclusion

"Tussin plus" is a syrup that is used as a method of treating dry cough in various pathologies of the respiratory system. The medicine helps to remove mucus from the bronchi and moisturize the tissues of the larynx. According to many consumers, the product is highly effective. In addition, the price of this medication is low. However, it should be remembered that the drug can cause symptoms of individual intolerance. In this case, it is necessary to contact a specialist to prescribe another medication with a similar effect, which will not provoke undesirable reactions of the body.

It is not recommended to change the medicine and the treatment regimen on your own. During the course of therapy with this syrup, the patient may experience side effects in the form of violations of activity digestive system, dizziness, rash. In such a situation, it is also necessary to stop taking the medication and decide on the choice of another drug.

In this article, you can read the instructions for using the drug Tussin. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Tussin in their practice are presented. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications were observed and side effects, possibly not declared by the manufacturer in the annotation. Tussin analogues in the presence of existing structural analogues. Use for the treatment of cough, including dry cough for colds, flu and SARS in adults, children, as well as during pregnancy and lactation. The composition of the drug.

Tussin- mucolytic and expectorant, reduces the viscosity of sputum, facilitates its removal and promotes the transition of an unproductive cough into a productive one. The duration of action with a single dose is 3.5-4 hours.

Guaifenesin has an expectorant effect by increasing the secretion of liquid components of bronchial mucus, depolymerization of acid mucopolysaccharides, and increasing the activity of the ciliated epithelium.

Dextromethorphan suppresses excessively intense afferent impulses from the mucous membrane of the respiratory tract, increases the cough threshold, reducing the intensity of dry, irritating cough. Dextromethorphan is a D-isomer of levorphanol, similar in strength to codeine, but does not have analgesic properties, does not inhibit the respiratory center and the activity of the ciliated epithelium. The duration of antitussive action is 5-6 hours.

Compound

Guaifenesin + excipients (Tussin).

Guaifenesin + Dextromethorphan hydrobromide + excipients (Tussin Plus).

Pharmacokinetics

Guaifenesin is rapidly absorbed from the gastrointestinal tract (25-30 minutes after ingestion). Penetrates into tissues containing acidic mucopolysaccharides. Metabolized in the liver. Excreted by the lungs (with sputum) and kidneys as inactive metabolites.

Dextromethorphan is rapidly absorbed from the gastrointestinal tract and its effect begins to appear after 15-30 minutes. Dextromethorphan is metabolized primarily by liver enzymes, undergoing O-demethylation, N-demethylation and partial binding to glucuronic acid and sulfates. In humans, (+)-3-hydroxy-g4-methylmorphinan, (+)-3-hydroxymorphinan, and traces of the unmetabolized drug may be detected in the urine after oral administration.

Indications

Cough with difficult expectoration of sputum inflammatory diseases upper respiratory tract:

• with acute viral infections and colds;
• with flu;
• with acute laryngitis, pharyngitis, tracheitis, bronchitis.

Release forms

Other dosage forms, be it tablets or solution, does not exist.

Instructions for use and dosing regimen

Syrup Tussin

Use no more than 4-6 single doses per day. The drug must be taken after meals.

Single dose: children from 2 to 6 years old - 1/2 -1 teaspoon (50-100 mg) with an interval of 6-8 hours. Children from 6 to 12 years old - 1-2 teaspoons (100-200 mg) 3- 4 times a day. Children from 12 years old and adults - 2-4 teaspoons (200-400 mg) 3-4 times a day.

Syrup Tussin Plus

Take orally after meals with a teaspoon or measuring cup.

For adults and children over 12 years old - 2 teaspoons every 4 hours.

For children (6-12 years old) - 1 teaspoon every 4 hours.

Side effect

• dyspepsia (nausea, vomiting);
• diarrhea;
• exacerbation peptic ulcer stomach and duodenum;
• dizziness;
• headache;
• drowsiness or insomnia;
• hyperexcitability (especially in children);
• allergic reactions (skin rash, urticaria, hyperthermia).

Contraindications

• severe organic diseases of the central nervous system;
• peptic ulcer of the stomach and duodenum;
• gastric bleeding (history);
• wet cough with copious sputum;
• simultaneous administration of drugs containing substances that are part of the drug Tussin Plus;
• children's age up to 2 years (Tussin), and up to 6 years (Tussin Plus);
• hypersensitivity to the components of the drug.

Use during pregnancy and lactation

Use with caution during pregnancy and lactation.

Use in children

Tussin Plus is contraindicated in children under 6 years old, Tussin - in children under 2 years old.

special instructions

It is possible to stain the urine pink.

Urinary 5-hydroxyindoleacetic acid (using the nitrosonaphthol reagent) may be falsely elevated due to the effect of guaifenesin metabolites on color (guaifenesin should be discontinued 48 hours prior to urine collection for this test).

Guaifenesin and its metabolites can cause discoloration in the determination of vanillylmandelic acid in the urine and falsely increase the results of the test with it for catechins (Guaifenesin should be stopped 48 hours before urine collection for this test).

Tussin Plus comes with a dosing cup with graduations 1 TSP = 1 teaspoon = 5 ml.

Influence on the ability to drive vehicles and control mechanisms

During the period of treatment, care should be taken when performing work that requires concentration, increased speed of motor and mental reactions, and also refrain from drinking alcohol.

drug interaction

Tussin Plus is compatible with bronchodilators, antimicrobial agents, cardiac glycosides.

Tussin Plus is not prescribed simultaneously with antitussives (including those containing codeine) and mucolytic agents.

Incompatible with drugs that inhibit MAO (including furazolidone, procarbazine, selegiline), which, when used simultaneously, can cause an adrenergic crisis, collapse, coma, dizziness, agitation, increased blood pressure, hyperpyrexia, intracranial bleeding, drowsiness, nausea, spasms , tremor.

Amiodarone, fluoxetine, quinidine, inhibiting the cytochrome P450 system, can increase the concentration of the drug in the blood.

Tobacco smoke can lead to an increase in the secretion of glands against the background of inhibition of the cough reflex.

Tussin's analogues

Structural analogues according to active substance:

• Coldrex broncho;
• Synetos.

Analogues for pharmacological group(antitussives):

• Alex Plus;
• Bronchitusen Vramed;
• Broncholine sage;
• Broncholitin;
• Bronchoton;
• Bronchocin;
• Glycodin;
• Grippostad Good Knight;
• Codelac;
• Codelac Broncho;
• Codelac phyto;
• Codelmixt;
• Codipront;
• Codterpin;
• Cofanol;
• Neo Codion;
• Neo Codion for adults;
• Neo Codion for children;
• Padevix;
• paracodamol;
• Rengalin;
• Tedein;
• Terasil D;
• Terkodin;
• Terpincode;
• Tussin plus;
• Fervex for dry cough.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.